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https://www.readbyqxmd.com/read/30551142/cytological-and-molecular-aspects-of-the-ageing-sperm
#1
Donatella Paoli, Giulia Pecora, Francesco Pallotti, Fabiana Faja, Marianna Pelloni, Andrea Lenzi, Francesco Lombardo
STUDY QUESTION: Is ageing associated with a decline in semen quality and molecular changes to human sperm? SUMMARY ANSWER: Semen quality declines with advancing age and characteristic molecular changes take place during the ageing process, including increased sperm DNA damage, altered sperm protamination and altered seminal plasma miRNA profile. WHAT IS KNOWN ALREADY: During ageing, the reproductive system is exposed to physiological changes and potentially damaging factors that may impair testicular function...
December 14, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30522016/er-shen-wan-extract-alleviates-polyuria-and-regulates-aqp-2-and-avpr-2-in-a-rat-model-of-spleen-kidney-yang-deficiency-induced-diarrhea
#2
Rui Xiong, Yidan Li, Kaixuan Zheng, Tingting Zhang, Mingyang Gao, Yun Li, Yumei Lian, Da Chen, Changjiang Hu
ETHNOPHARMACOLOGICAL RELEVANCE: Er Shen Wan (ESW), has been empirically used for treating spleen-kidney Yang deficiency (SKYD) syndrome in Traditional Chinese medicine (TCM) for centuries and shows a variety of activities. The medicinal formula is a mixture of two component herbs, Psoraleae Fructus (PF, Bu-Gu-Zhi in Chinese) and Myristicae Semen (MS, Rou-Dou-Kou in Chinese). The current study was designed to evaluate ESWP antidiuretic treatment of polyuria and to explore potential mechanisms of renal water metabolism in the rat model of SKYD-induced diarrhea...
December 3, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/30517657/high-risk-human-papillomavirus-in-semen-is-associated-with-poor-sperm-progressive-motility-and-a-high-sperm-dna-fragmentation-index-in-infertile-men
#3
Luca Boeri, Paolo Capogrosso, Eugenio Ventimiglia, Filippo Pederzoli, Walter Cazzaniga, Francesco Chierigo, Edoardo Pozzi, Massimo Clementi, Paola Viganò, Emanuele Montanari, Francesco Montorsi, Andrea Salonia
STUDY QUESTION: Does the presence of human papillomavirus (HPV) in semen impact seminal parameters and sperm DNA quality in white European men seeking medical help for primary couple's infertility? SUMMARY ANSWER: HPV seminal infections involving high-risk (HR) genotypes are associated with impaired sperm progressive motility and sperm DNA fragmentation (SDF) values. WHAT IS KNOWN ALREADY: HPV is commonly present in semen samples. However, whether the presence of HPV in semen is actually associated with impaired sperm parameters and SDF values have yet to be elucidated...
December 4, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30515955/the-duration-of-infertility-affects-semen-parameters-in-primary-infertile-men-results-of-a-single-centre-cross-sectional-study
#4
Luca Boeri, Eugenio Ventimiglia, Paolo Capogrosso, Angela Pecoraro, Filippo Pederzoli, Walter Cazzaniga, Edoardo Pozzi, Massimo Alfano, Paola Viganò, Emanuele Montanari, Francesco Montorsi, Andrea Salonia
OBJECTIVE: To assess the relationship between the duration of infertility (DI) and the seminal parameters of a cohort of White-European primary infertile men. PATIENTS AND METHODS: Data from 1644 infertile men were analysed. Patients were grouped according to the self-reported DI into 12-month time frames. Semen analysis values were assessed based on 2010 World Health Organisation reference criteria. Descriptive statistics tested the difference in clinical, hormonal and seminal parameters between groups...
December 4, 2018: BJU International
https://www.readbyqxmd.com/read/30515618/association-between-parental-anthropometric-measures-and-the-outcomes-of-intracytoplasmic-sperm-injection-cycles
#5
Amanda Setti, Gabriela Halpern, Daniela Braga, Rita Figueira, Assumpto Iaconelli, Edson Borges
PURPOSE: To study the association between body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR), and response to controlled ovarian stimulation, semen quality, and intracytoplasmic sperm injection (ICSI) outcomes. METHODS: This prospective observational study included data from 402 couples undergoing ICSI between January/2010-September/2016. Participants had their weight, height, waist, and hip measured before ICSI treatment...
December 5, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/30515344/simultaneous-quantification-of-six-bioactive-components-in-decoction-of-ziziphi-spinosae-semen-using-ultrahigh-performance-liquid-chromatography-coupled-with-triple-quadrupole-mass-spectrometry
#6
Xiao Liu, Xiaochai Zhu, Hui Zhu, Li Xie, Jia Ma, Yinghui Xu, Qigang Zhou, Zejun Wu, Baochang Cai
This paper was conducted to develop a method containing ultrahigh performance liquid chromatography coupled with triple-quadrupole tandem mass spectrometry for simultaneous quantification of six bioactive components in the decoction of Ziziphi spinosae Semen. Analysis was performed on an Agilent ZORBAX Extend-C18 column (2.1 × 100 mm, 1.8  μ m) and eluted with a mobile phase system consisting of acetonitrile and water under a gradient program with a flow rate of 0.3 ml/min. The injection volume was 2  μ l...
2018: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/30515064/hypospermia-improvement-in-dogs-fed-on-a-nutraceutical-diet
#7
Francesco Ciribé, Riccardo Panzarella, Maria Carmela Pisu, Alessandro Di Cerbo, Gianandrea Guidetti, Sergio Canello
Male dog infertility may represent a serious concern in the canine breeding market. The aim of this clinical evaluation was to test the efficacy of a commercially available nutraceutical diet, enriched with Lepidium meyenii, Tribulus terrestris, L-carnitine, zinc, omega-3 (N-3) fatty acids, beta-carotene, vitamin E, and folic acid, in 28 male dogs suffering from infertility associated with hypospermia. All dogs received the diet over a period of 100 days. At the end of the evaluation period, no adverse effects, including head and tail anomalies percentage onset, were reported...
2018: TheScientificWorldJournal
https://www.readbyqxmd.com/read/30509667/scrotal-infrared-digital-thermography-predicts-effects-of-thermal-stress-on-buffalo-bubalus-bubalis-semen
#8
Maneesh Kumar Ahirwar, Mukund Amritrao Kataktalware, Heartwin Amaladhas Pushpadass, Sakthivel Jeyakumar, Soumitra Jash, Sayyad Nazar, Letha Devi G, John P Kastelic, Kerekoppa Puttaiah Ramesha
The objective was to use scrotal infrared digital thermography to evaluate effects of thermal stress on semen quality of Murrah buffalo (Bubalus bubalis) breeding bulls. Ejaculates from 109 Murrah bulls maintained at three semen stations were evaluated for: ejaculate volume, sperm concentration (SCON), initial motility (IM), percent live sperm (LIVE), acrosome integrity of fresh semen (AIFS), plasma membrane integrity of fresh semen (PMIFS), head abnormalities of fresh semen (HAFS), midpiece abnormalities of fresh semen (MPAFS), tail abnormalities of fresh semen (TAFS), post-thaw motility (PTM), acrosome integrity of post-thawed semen (AIPT) and plasma membrane integrity of post-thawed semen (PMIPT)...
December 2018: Journal of Thermal Biology
https://www.readbyqxmd.com/read/30475967/effect-of-nut-consumption-on-semen-quality-and-functionality-in-healthy-men-consuming-a-western-style-diet-a-randomized-controlled-trial
#9
Albert Salas-Huetos, Rocío Moraleda, Simona Giardina, Ester Anton, Joan Blanco, Jordi Salas-Salvadó, Mònica Bulló
Background: Human semen quality has declined in industrialized countries. Pollution, smoking, and the consumption of a Western-style diet are all hypothesized as potential causes. Objective: We evaluated the effect of chronic consumption of nuts on changes in conventional semen parameters and the potential mechanisms implicated. Design: The FERTINUTS study was a 14-wk randomized, controlled, parallel trial. A total of 119 healthy men, aged 18-35 y, were allocated to 1 of 2 intervention groups: one group was fed the usual Western-style diet enriched with 60 g of a mixture of nuts/d (nut group), and the other was fed the usual Western-style diet avoiding nuts (control group)...
November 1, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/30466985/withania-somnifera-indian-ginseng-in-male-infertility-an-evidence-based-systematic-review-and-meta-analysis
#10
REVIEW
Sharanbasappa Durg, Shivakumar Badamaranahalli Shivaram, Sachin Bavage
BACKGROUND: Withania somnifera Dunal, commonly known as Indian ginseng, has been in use since ancient times as anti-stress agent, aphrodisiac, for impotence and infertility treatment. PURPOSE: To evaluate the efficacy and safety of W. somnifera treatment in infertile men. STUDY DESIGN: An evidence-based systematic review and meta-analysis using Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. METHODS: Published literature was searched in PubMed/MEDLINE, EMBASE, Scopus, the Cochrane Library, and DHARA...
November 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/30462692/association-between-paternal-smoking-at-the-time-of-pregnancy-and-the-semen-quality-in-sons
#11
Jonatan Axelsson, Sally Sabra, Lars Rylander, Anna Rignell-Hydbom, Christian H Lindh, Aleksander Giwercman
BACKGROUND: Maternal smoking during pregnancy has repeatedly been associated with decreased sperm counts in sons. Nevertheless, our team recently detected a lower total sperm count in the sons of smoking fathers as compared to sons of non-smoking fathers. Since paternal and maternal tobacco smoking often coincide, it is difficult to discriminate whether effects are mediated paternally or maternally when using questionnaire- or register-based studies. Therefore, getting an objective measure of the maternal nicotine exposure level during pregnancy might help disentangling the impact of paternally and maternally derived exposure...
2018: PloS One
https://www.readbyqxmd.com/read/30452659/anogenital-distance-is-associated-with-semen-quality-but-not-reproductive-hormones-in-1106-young-men-from-the-general-population
#12
L Priskorn, A K Bang, L Nordkap, M Krause, J Mendiola, T K Jensen, A Juul, N E Skakkebaek, S H Swan, N Jørgensen
STUDY QUESTION: Is anogenital distance (AGD) associated with semen quality and reproductive hormones in men from the general population? SUMMARY ANSWER: Short AGD measured from the anus to the base of scrotum (AGDAS) was associated with reduced sperm counts and morphology but not with sperm motility or reproductive hormones. WHAT IS KNOWN ALREADY: AGD is longer in males than in females. In rodents, AGD is a well-established and sensitive marker of disruption during the masculinization programming window in utero and it has been suggested to be so in humans as well...
November 17, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30448091/the-relationship-between-sperm-dna-fragmentation-free-radicals-and-antioxidant-capacity-with-idiopathic-repeated-pregnancy-loss
#13
Narges Kamkar, Fariba Ramezanali, Marjan Sabbaghian
More than two consecutive miscarriages in less than 20 weeks of gestation is defined as recurrent spontaneous miscarriage. Various causes such as uterine anatomical anomalies, genetic factors, and infectious and endocrine disorders have been reported for RPL. However, approximately 50% of the causes are unknown, which can be due to male factors. Several studies have been done on semen parameters to determine the unknown causes and risk factors for miscarriages, however, only studying common semen parameters have not been sufficient...
November 14, 2018: Reproductive Biology
https://www.readbyqxmd.com/read/30416195/effect-of-bariatric-surgery-on-semen-parameters-a-systematic-review-and-meta-analysis
#14
Yong Wei, Quanbing Chen, Wenhui Qian
BACKGROUND The present systematic review and meta-analysis was performed to explore the possible effect of bariatric surgery on semen parameters. MATERIAL AND METHODS Studies on the effect of bariatric surgeries on semen parameters were collected by searching Cochrane Library, PUBMED, EMBASE, MEDLINE, and CNKI databases. We extracted information on essential data and outcome measures, including study design, bariatric surgery, and semen parameters at baseline and after the surgery from the included studies, and STATA 12...
November 12, 2018: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/30407511/association-between-bmi-and-semen-quality-an-observational-study-of-3966-sperm-donors
#15
Jixuan Ma, Li Wu, Yun Zhou, Hai Zhang, Chengliang Xiong, Zhe Peng, Wei Bao, Tianqing Meng, Yuewei Liu
STUDY QUESTION: What is the relationship between abnormal BMI and semen quality? SUMMARY ANSWER: Underweight was significantly associated with lower sperm concentration, total sperm number and total motile sperm count, while overweight was significantly associated with lower semen volume, total sperm number and total motile sperm count. WHAT IS KNOWN ALREADY: Abnormal BMI has been associated with lower semen quality, but the results remain somewhat controversial...
November 8, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30403786/endocrine-disruption-of-androgenic-activity-by-perfluoroalkyl-substances-clinical-and-experimental-evidence
#16
Andrea Di Nisio, Iva Sabovic, Umberto Valente, Simone Tescari, Maria Santa Rocca, Diego Guidolin, Stefano Dall'Acqua, Laura Acquasaliente, Nicola Pozzi, Mario Plebani, Andrea Garolla, Carlo Foresta
Background: Considerable attention has been paid to perfluoroalkyl compounds (PFCs) because of their worldwide presence in humans, wildlife, and environment. A wide variety of toxicological effects is well supported in animals, including testicular toxicity and male infertility. For these reasons, the understanding of epidemiological associations and of the molecular mechanisms involved in the endocrine-disrupting properties of PFCs on human reproductive health is a major concern. Objective: To investigate the relationship between PFCs exposure and male reproductive health...
November 6, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/30396773/no-independent-associations-between-preconception-paternal-dietary-patterns-and-embryonic-growth-the-predict-study
#17
Elsje C Oostingh, Iris de Vos, Annelies C Ham, Elske M Brouwer-Brolsma, Sten P Willemsen, Alex J Eggink, Eric A P Steegers, Régine P M Steegers-Theunissen
BACKGROUND & AIM: Several studies show the importance of periconceptional maternal dietary patterns on human embryonic growth. Healthy paternal nutrition has been associated with better semen quality and fecundability, however, evidence on the impact on pregnancy outcome is limited. Therefore, the aim of this study was to investigate the association between preconception paternal dietary patterns and first trimester embryonic growth using the parameters longitudinal crown-rump length (CRL) and embryonic volume (EV)...
October 24, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/30391831/patterns-of-expression-of-sperm-and-seminal-plasma-micrornas-in-boar-semen
#18
Vanmathy Kasimanickam, Mary Buhr, Ramanathan Kasimanickam
Although sperm and seminal plasma differ in their origin, biophysical and biochemical properties of seminal plasma influence the sperm function. Seminal plasma is a fluid medium containing substances from testes, epididymides and accessory glands. Composition of seminal plasma varies among animal species and in boars, prostate and bulbourethral glands are major contributors to the volume and contents. While the origin of some components of seminal plasma are known, the source of recently discovered seminal plasma microRNAs remains unknown, in part due to the difficulty of recovering and characterizing RNA from porcine sperm and seminal plasma...
October 26, 2018: Theriogenology
https://www.readbyqxmd.com/read/30389382/secular-trends-in-semen-parameters-among-men-attending-a-fertility-center-between-2000-and-2017-identifying-potential-predictors
#19
Lidia Mínguez-Alarcón, Paige L Williams, Yu-Han Chiu, Audrey J Gaskins, Feiby L Nassan, Ramace Dadd, John Petrozza, Russ Hauser, Jorge E Chavarro
BACKGROUND: Multiple meta-analyses have shown sperm count declines in Western countries spanning eight decades. Secular trends in other parameters remain unclear, as are potential predictors of these trends. OBJECTIVE: To analyze secular trends in semen quality and to evaluate whether factors previously found to be related to semen quality were responsible for these patterns. METHODS: This is a prospective study including 936 men of couples seeking infertility treatment who provided 1618 semen samples at a single center (2000-2017)...
October 30, 2018: Environment International
https://www.readbyqxmd.com/read/30368128/evaluation-of-the-effect-of-mating-intrauterine-deposition-of-raw-seminal-plasma-or-seminal-plasma-purified-%C3%AE-ngf-on-endometrial-vascularization-in-llamas
#20
Felipe Urra, Marcelo H Ratto, Mauricio Silva
The aim of this study was to evaluate the endometrial vascularization area (EVA) of both uterine horns in llamas subjected to different intrauterine treatments resembling physiological conditions after a single mating. Llamas with a growing follicle (≥8 mm) were randomly assigned to: a) single mating with a fertile male (mating; positive control; n = 6); b) intramuscular administration of 50 μg of gonadorelin acetate plus an intrauterine infusion of 4 ml of PBS (GnRH; negative control; n = 4); c) intrauterine infusion of 4 ml of raw llama seminal plasma (SP; n = 4) or d) intrauterine infusion of 10 mg of β-NGF purified from llama semen diluted in 4 ml of PBS (spβ-NGF; n = 6)...
October 9, 2018: Theriogenology
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