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https://www.readbyqxmd.com/read/30255454/coolhair-a-prospective-randomized-trial-to-investigate-the-efficacy-and-tolerability-of-scalp-cooling-in-patients-undergoing-neo-adjuvant-chemotherapy-for-early-breast-cancer
#1
Katharina Smetanay, Philippe Junio, Manuel Feißt, Julia Seitz, Jessica Cecile Hassel, Luisa Mayer, Lina Maria Matthies, Arina Schumann, André Hennigs, Jörg Heil, Christof Sohn, Dirk Jaeger, Andreas Schneeweiss, Frederik Marmé
PURPOSE: Chemotherapy-induced alopecia (CIA) is a distressing side effect for women with breast cancer undergoing chemotherapy. Scalp cooling is a method aiming to prevent CIA, but its efficacy is not well defined. Randomized trials until recently and at the time this trial was designed have been lacking. METHODS: Patients undergoing (neo)adjuvant chemotherapy for early breast cancer (EBC) were randomized to scalp cooling (CAP) or observation (NoCAP). All patients received 18-24 weeks of anthracycline- and/or taxane-based chemotherapy...
September 25, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/30147638/a-slow-cooling-rate-in-situ-cell-for-long-duration-studies-of-mineral-precipitation-in-cold-aqueous-environments-on-earth-and-other-planetary-bodies
#2
Stephen P Thompson, Hilary Kennedy, Sarah J Day, Annabelle R Baker, Benjamin M Butler, Emmal Safi, Jon Kelly, Andrew Male, Jonathan Potter, Tom Cobb, Claire A Murray, Chiu C Tang, Aneurin Evans, Ronaldo Mercado
Liquid oceans and ice caps, along with ice crusts, have long been considered defining features of the Earth, but space missions and observations have shown that they are in fact common features among many of the solar system's outer planets and their satellites. Interactions with rock-forming materials have produced saline oceans not dissimilar in many respects to those on Earth, where mineral precipitation within frozen seawater plays a significant role in both determining global properties and regulating the environment in which a complex ecosystem of extremophiles exists...
August 1, 2018: Journal of Applied Crystallography
https://www.readbyqxmd.com/read/30143301/thermal-modelling-of-controlled-scalp-hypothermia-using-a-thermoelectric-cooling-cap
#3
Mark Baldry, Victoria Timchenko, Chris Menictas
This study presents a novel, thermoelectric cryotherapy cap that aims to provide effective and controlled scalp cooling to prevent hair loss for chemotherapy patients. The cap's design consists of multiple thermoelectric coolers (TECs) evenly spaced and bonded to a soft thermal interface material, tightly fitted to a patient's head. A numerical model is developed to assess the performance of alternative cap designs in relation to their ability to achieve hair follicle hypothermia. Under ideal conditions, 26...
August 2018: Journal of Thermal Biology
https://www.readbyqxmd.com/read/30130407/radiative-cooling-of-surface-modified-gold-nanorods-upon-pulsed-infrared-photoexcitation
#4
Shao-Syuan Guo, Li-Kang Chu
Transient infrared emissions of gold nanorods capped with various materials (AuNR@X, X = CTAB, PSS, mPEG, and SiO2 ) upon ∼70-μs pulsed 1064 nm excitation of their longitudinal surface plasmonic bands were collected with a time-resolved step-scan Fourier-transform spectrometer. Comparing the observed emission contours with the blackbody radiation spectra revealed that parts of the additional emission intensity at low wavenumbers (1300-1000 cm-1 ) were attributed to the vibrational modes of the capping materials, suggesting that the photothermal energy of AuNRs can be thermalized not only via blackbody radiation but also via radiative and nonradiative processes of the capping materials...
September 6, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29967546/synchronous-tropical-and-polar-temperature-evolution-in-the-eocene
#5
Margot J Cramwinckel, Matthew Huber, Ilja J Kocken, Claudia Agnini, Peter K Bijl, Steven M Bohaty, Joost Frieling, Aaron Goldner, Frederik J Hilgen, Elizabeth L Kip, Francien Peterse, Robin van der Ploeg, Ursula Röhl, Stefan Schouten, Appy Sluijs
Palaeoclimate reconstructions of periods with warm climates and high atmospheric CO2 concentrations are crucial for developing better projections of future climate change. Deep-ocean1,2 and high-latitude3 palaeotemperature proxies demonstrate that the Eocene epoch (56 to 34 million years ago) encompasses the warmest interval of the past 66 million years, followed by cooling towards the eventual establishment of ice caps on Antarctica. Eocene polar warmth is well established, so the main obstacle in quantifying the evolution of key climate parameters, such as global average temperature change and its polar amplification, is the lack of continuous high-quality tropical temperature reconstructions...
July 2018: Nature
https://www.readbyqxmd.com/read/29923063/persistent-major-alopecia-following-adjuvant-docetaxel-for-breast-cancer-incidence-characteristics-and-prevention-with-scalp-cooling
#6
M Martín, J C de la Torre-Montero, S López-Tarruella, K Pinilla, A Casado, S Fernandez, Y Jerez, J Puente, I Palomero, R González Del Val, M Del Monte-Millan, T Massarrah, C Vila, B García-Paredes, J A García-Sáenz, A Lluch
BACKGROUND: Persistent alopecia (PA) after docetaxel has been recently described. The aim of our study is to establish the incidence and characteristics of PA following adjuvant docetaxel for breast cancer (BC) and to test the ability of scalp cooling in prevention. PATIENTS AND METHODS: BC patients receiving adjuvant chemotherapy followed or not by endocrine therapy (and a control group receiving only endocrine therapy) were interviewed in a single institution at 1...
June 19, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29805513/effect-of-mild-hypothermia-on-expression-of-inflammatory-factors-in-surrounding-tissue-after-minimally-invasive-hematoma-evacuation-in-the-treatment-of-hypertensive-intracerebral-hemorrhage
#7
Jianhua Zhao, Qing Mao, Zhongxin Qian, Jun Zhu, Zhun Qu, Chao Wang
Mild hypothermia combined with minimally invasive hematoma evacuation was evaluated in the treatment of hypertensive intracerebral hemorrhage to reduce inflammatory response of brain tissue around hematoma and ameliorate brain function, and to investigate its safety, effectiveness and feasibility. A total of 206 patients with acute spontaneous hypertensive intracerebral hemorrhage were collected clinically and randomly divided into minimally invasive hematoma evacuation group (group A) and mild hypothermia combined with minimally invasive hematoma evacuation (group B)...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29764556/-extra-longtime-continuous-chest-compression-to-rescue-cardiopulmonary-arrest-a-case-report-and-the-literature-review
#8
Yan Zhang, Tianxue Yue, Kexin Sun, Jiang Wang, Ruiwu Zhu
The new cardiopulmonary resuscitation (CPR) guideline emphasize the importance of chest compression, which was considered as the first step to CPR. The duration for CPR is usually limited to 30 minutes. With the development of new technology and evidence-based medicine, the success of extra longtime CPR has become possible, which is of great significance to some patients with cardiac arrest (CA), but the time limit has not been determined. On February 23rd in 2016, a 76-year-old female patient with respiratory and cardiac arrest who was on the third day after transurethral resection of bladder tumor (TUR-BT) was admitted to the intensive care unit of the General Hospital of Fushun Mining Bureau...
May 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29757650/analytical-model-for-diffusive-evaporation-of-sessile-droplets-coupled-with-interfacial-cooling-effect
#9
Tuan A H Nguyen, Simon R Biggs, Anh V Nguyen
Current analytical models for sessile droplet evaporation do not consider the nonuniform temperature field within the droplet and can overpredict the evaporation by 20%. This deviation can be attributed to a significant temperature drop due to the release of the latent heat of evaporation along the air-liquid interface. We report, for the first time, an analytical solution of the sessile droplet evaporation coupled with this interfacial cooling effect. The two-way coupling model of the quasi-steady thermal diffusion within the droplet and the quasi-steady diffusion-controlled droplet evaporation is conveniently solved in the toroidal coordinate system by applying the method of separation of variables...
June 12, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29529389/management-of-chemotherapy-induced-alopecia-with-scalp-cooling
#10
Megan Kruse, Jame Abraham
Chemotherapy-induced alopecia is a common and distressing adverse effect of many types of chemotherapy. Scalp cooling has been used since the 1970s for prevention of chemotherapy-induced alopecia; however, most data regarding this treatment modality are retrospective in nature, and use in the United States has been limited by safety concerns, specifically the potential for scalp metastases. Two prospective studies of scalp-cooling systems performed in the United States were published within the last year and add evidence supporting the efficacy and safety of scalp cooling in preventing chemotherapy-induced alopecia in patients receiving chemotherapy for solid tumor malignancies...
March 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29214505/efficacy-and-safety-of-three-cryotherapy-devices-for-wart-treatment-a-randomized-controlled-investigator-blinded-comparative-study
#11
Imko Walczuk, Frank Eertmans, Bart Rossel, Agnieszka Cegielska, Eggert Stockfleth, Andre Antunes, Els Adriaens
INTRODUCTION: Cutaneous warts are common skin lesions, caused by human papillomavirus. For years, liquid nitrogen is the cryogen of choice for wart treatment. Alternatively, several cryogenic devices for home treatment are commercially available. The present trial assessed efficacy and safety of a novel nitrous oxide-based cryogenic device for home use (EndWarts Freeze® in Europe, Compound W® Nitro-Freeze in the USA). METHODS: This investigator-blinded, controlled, randomized study compared the nitrous oxide device (test product) with a dimethylether propane-based product (Wartner® ; comparator 1)...
June 2018: Dermatology and Therapy
https://www.readbyqxmd.com/read/29148703/bond-energy-driven-low-or-high-angle-grain-boundary-movement-mediated-synthesis-of-porous-se-te-for-use-in-water-splitting-reactions
#12
Anup Kumar Sasmal, Arpan Kumar Nayak, Prashant Kartikeya, Debabrata Pradhan, Tarasankar Pal
Herein, for the first time, we applied the metal-metal-bond-energy factor to the evolution of a porous Se-Te alloy. The porous Se-Te material has been prepared from the constituents' elemental states, through only a heating-cooling process in silicone oil without the use of any reagent, surfactant, or capping agent. Surprisingly, the reaction occurred at a much lower temperature (240 °C) than the mp (450 °C) of Te0 . The reaction's nucleation and growth by means of varied bond energy have been clarified for the first time...
December 6, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28906503/release-of-irretrievable-abutment-healing-caps-using-cooling-proof-of-concept-and-clinical-recommendations
#13
Kifah Blal, Ori Rimon, Nardy Casap
PURPOSE: To study the relation between irretrievable abutment healing caps (AHCs), temperature, and the torque required to remove the AHCs from implants. MATERIALS AND METHODS: Twenty implants, 13 mm long and 4.2 mm in diameter, were inserted into four acrylic boxes and covered with acrylic resin. An AHC was screwed into each implant, using a 30 N/cm torque. The acrylic blocks were placed in a 37°C water bath, and subsequently, a block was removed from the bath, the AHCs were cooled, and the torque needed to release each AHC from the implant was measured using a torque wrench...
September 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28671600/low-cost-and-rapid-fabrication-of-metallic-nanostructures-for-sensitive-biosensors-using-hot-embossing-and-dielectric-heating-nanoimprint-methods
#14
Kuang-Li Lee, Tsung-Yeh Wu, Hsuan-Yeh Hsu, Sen-Yeu Yang, Pei-Kuen Wei
We propose two approaches-hot-embossing and dielectric-heating nanoimprinting methods-for low-cost and rapid fabrication of periodic nanostructures. Each nanofabrication process for the imprinted plastic nanostructures is completed within several seconds without the use of release agents and epoxy. Low-cost, large-area, and highly sensitive aluminum nanostructures on A4 size plastic films are fabricated by evaporating aluminum film on hot-embossing nanostructures. The narrowest bandwidth of the Fano resonance is only 2...
July 2, 2017: Sensors
https://www.readbyqxmd.com/read/28654061/the-inverted-heart-model-for-interstitial-transudate-collection-from-the-isolated-rat-heart
#15
Kezhe Tan, Zhaoping Ding, Bodo Steckel, Sonja Hartwig, Stefan Lehr, Xiaoming Deng, Jürgen Schrader
The present protocol describes a unique approach that enables the collection of cardiac transudate (CT) from the isolated, saline-perfused rat heart. After isolation and retrograde perfusion of the heart according to the Langendorff technique, the heart is inverted into an upside-down position and is mechanically stabilized by a balloon catheter inserted into the left ventricle. Then, a thin latex cap - previously cast to match the average size of the rat heart - is placed over the epicardial surface. The outlet of the latex cap is connected to silicon tubing, with the distal opening 10 cm below the base level of the heart, creating slight suction...
June 20, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28141719/-more-than-meets-the-eye-when-the-neonatal-course-may-impact-several-years-out
#16
Fadiyla Dopwell, John Maypole, Bharati Sinha, Heidi Currier, William DeBassio, Marilyn Augustyn
Nadia is a 7-year-old girl who you have followed since her discharge from the Neonatal Intensive Care Unit (NICU). Her parents are here today for an urgent visit with behavioral concerns, such as inattention, hyperactivity, and aggression.Nadia is a former 40-weeker born through vacuum-assisted vaginal delivery at 9 pounds 7 ounces. Her delivery was complicated with shoulder dystocia, which resulted in resuscitation. Her Apgar scores were 1, 3, and 4 at 1, 5, and 10 minutes, respectively. After intubation and stabilization on mechanical ventilation, Nadia was transferred to the NICU...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28059257/calculation-of-temperature-profiles-in-solid-state-laser-disks-mounted-on-multi-layered-heat-spreaders-using-hankel-transforms
#17
Norman Hodgson, Andrea Caprara
The main challenge in disk laser design is the realization of efficient heat removal from the pumped area by optimizing the heat spreader design and the water impingement cooling. This generally requires the calculation of the temperature distribution in the disk by numerically solving the heat conduction equation using finite element algorithms. We have developed a simple method to calculate disk temperature profiles that is based on analytically solving the heat conduction equation in Hankel transform space...
December 20, 2016: Applied Optics
https://www.readbyqxmd.com/read/27981953/the-fabrication-and-thermal-properties-of-bismuth-aluminum-oxide-nanothermometers
#18
Chiu-Yen Wang, Shih-Hsun Chen, Ping-Hsin Tsai, Chung-Han Chiou, Sheng-Jen Hsieh
Bismuth (Bi) nanowires, well controlled in length and diameter, were prepared by using an anodic aluminum oxide (AAO) template-assisted molding injection process with a high cooling rate. A high performance atomic layer deposition (ALD)-capped bismuth-aluminum oxide (Bi-Al2 O3 ) nanothermometer is demonstrated that was fabricated via a facile, low-cost and low-temperature method, including AAO templated-assisted molding injection and low-temperature ALD-capped processes. The thermal behaviors of Bi nanowires and Bi-Al2 O3 nanocables were studied by in situ heating transmission electron microscopy...
January 27, 2017: Nanotechnology
https://www.readbyqxmd.com/read/27934447/design-and-performance-validation-of-a-conductively-heated-sealed-vessel-reactor-for-organic-synthesis
#19
David Obermayer, Desiree Znidar, Gabriel Glotz, Alexander Stadler, Doris Dallinger, C Oliver Kappe
A newly designed robust and safe laboratory scale reactor for syntheses under sealed-vessel conditions at 250 °C maximum temperature and 20 bar maximum pressure is presented. The reactor employs conductive heating of a sealed glass vessel via a stainless steel heating jacket and implements both online temperature and pressure monitoring in addition to magnetic stirring. Reactions are performed in 10 mL borosilicate vials that are sealed with a silicone cap and Teflon septum and allow syntheses to be performed on a 2-6 mL scale...
December 2, 2016: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/27905699/green-light-vaporization-of-the-prostate-is-it-an-adult-technique
#20
REVIEW
Aldo Brassetti, Cosimo DE Nunzio, Nicolas B Delongchamps, Cristian Fiori, Francesco Porpiglia, Andrea Tubaro
INTRODUCTION: Intending to overcome transurethral resection of the prostate (TURP) in terms of safety maintaining its efficacy profile, have led to the introduction of minimally invasive laser therapies to treat men with lower urinary tract symptoms (LUTS) secondary to benign prostatic obstruction (BPO), each one with its unique properties. The aim of this review was to analyze and summarize all the existing data regarding the 180 W Xcelerated Performance System (XPS) photoselective vaporization of the prostate (PVP)...
April 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
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