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https://www.readbyqxmd.com/read/28736826/impact-of-respiratory-motion-and-acquisition-settings-on-spect-liver-dosimetry-for-radioembolization
#1
Remco Bastiaannet, Max A Viergever, Hugo W A M de Jong
PURPOSE: Respiratory motion may impose significant inaccuracies on emission activity estimation in quantitative SPECT. This effect may be a major issue in dosimetry as used in management of liver radioembolization. The purpose of this study was to investigate the impact of respiratory motion on radioembolization liver dosimetry for different SPECT acquisition settings. METHODS: In a series of SPECT/CT Monte Carlo simulations using several digital XCAT phantoms, the following parameters were varied: breathing/non-breathing, liver tumor size (0...
July 24, 2017: Medical Physics
https://www.readbyqxmd.com/read/28730902/relationships-between-adolescent-body-mass-index-physical-activity-and-sensory-processing-patterns-relations-entre-l-indice-de-masse-corporelle-l-activit%C3%A3-physique-et-les-sch%C3%A3-mes-d-int%C3%A3-gration-sensorielle-des-adolescents
#2
Joan Ziegler Delahunt, Lisa A Mische Lawson
BACKGROUND: Trends show a significant decline with adolescent physical activity (PA). Knowledge regarding how sensory-processing patterns and body mass index (BMI) relate to adolescents' PA participation is scarce. PURPOSE: This study investigated if relationships exist between adolescent BMI, sensory processing, and PA participation. METHOD: This correlational study collected data from 141 adolescents who completed the Adolescent/Adult Sensory Profile and the Physical Activity Questionnaire-Adolescent...
June 2017: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://www.readbyqxmd.com/read/28726873/local-decomposition-of-imaginary-polarizabilities-and-dispersion-coefficients
#3
Ignat Harczuk, Balazs Nagy, Frank Jensen, Olav Vahtras, Hans Ågren
We present a new way to compute the two-body contribution to the dispersion energy using ab initio theory. By combining the complex polarization propagator method and the LoProp transformation, local contributions to the Casimir-Polder interaction is obtained. The full dispersion energy in dimer systems consisting of pairs of molecules including H2, N2, CO, CH4, pyridine, and benzene is investigated, where anisotropic as well as isotropic models of dispersion are obtained using a decomposition scheme for the dipole-dipole polarizability...
July 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28718392/efficient-body-fat-estimation-using-multistage-pair-ranked-set-sampling
#4
M Mahdizadeh, Ehsan Zamanzade
Rank-based sampling methods are applicable in settings where precise measurements are expensive, but small sets of units can be accurately ranked at negligible cost. This article introduces one such a design, called multistage pair ranked set sampling. It mitigates ranking burden associated with a competitor scheme, namely multistage ranked set sampling. The mean estimator in multistage pair ranked set sampling is unbiased, and under perfect rankings has variance no larger than its simple random sampling counterpart...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/28712283/stereotactic-radiotherapy-of-the-prostate-fractionation-and-utilization-in-the-united-states
#5
Joseph P Weiner, David Schwartz, Meng Shao, Virginia Osborn, Kwang Choi, David Schreiber
PURPOSE: To analyze the utilization and fractionation of extreme hypofractionation via stereotactic body radiotherapy (SBRT) in the treatment of prostate cancer. MATERIALS AND METHODS: Data was analyzed on men diagnosed with localized prostate cancer between 2004-2012 and treated with definitive-intent radiation therapy, as captured in the National Cancer Database. This database is a hospital-based registry that collects an estimated 70% of all diagnosed malignancies in the United States...
June 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28711049/quantitative-estimation-of-localization-errors-of-3d-transition-metal-pseudopotentials-in-diffusion-monte-carlo
#6
Allison L Dzubak, Jaron T Krogel, Fernando A Reboredo
The necessarily approximate evaluation of non-local pseudopotentials in diffusion Monte Carlo (DMC) introduces localization errors. We estimate these errors for two families of non-local pseudopotentials for the first-row transition metal atoms Sc-Zn using an extrapolation scheme and multideterminant wavefunctions. Sensitivities of the error in the DMC energies to the Jastrow factor are used to estimate the quality of two sets of pseudopotentials with respect to locality error reduction. The locality approximation and T-moves scheme are also compared for accuracy of total energies...
July 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28708611/upflow-anaerobic-sludge-blanket-and-aerated-constructed-wetlands-for-swine-wastewater-treatment-a-pilot-study
#7
F Masi, A Rizzo, N Martinuzzi, S D Wallace, D Van Oirschot, P Salazzari, E Meers, R Bresciani
Swine wastewater management is often affected by two main issues: a too high volume for optimal reuse as a fertilizer and a too high strength for an economically sustainable treatment by classical solutions. Hence, an innovative scheme has been tested to treat swine wastewater, combining a low cost anaerobic reactor, upflow anaerobic sludge blanket (UASB), with intensified constructed wetlands (aerated CWs) in a pilot scale experimental study. The swine wastewater described in this paper is produced by a swine production facility situated in North Italy...
July 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28705085/international-survey-of-als-experts-about-critical-questions-for-assessing-patients-with-als
#8
Mamede De Carvalho, Adam Ryczkowski, Peter Andersen, Marta Gromicho, Julian Grosskreutz, Magdalena Kuźma-Kozakiewicz, Susanne Petri, Maria Piotrkiewicz, Gabriel Miltenberger Miltenyi
OBJECTIVE: To define an applicable dataset for ALS patient registries we weighted specific clinical items as scored by worldwide ALS experts. METHODS: Sixty participants were invited based on relevant clinical work, publications and personal acquaintance. They rated 160 clinical items consensually agreed by the members of our project, incorporating specialists from five European Centres. Scoring scheme was defined as: 1 - essential; 2 - important; 3 - not very important...
July 13, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28698501/energy-harvesting-based-body-area-networks-for-smart-health
#9
Yixue Hao, Limei Peng, Huimin Lu, Mohammad Mehedi Hassan, Atif Alamri
Body area networks (BANs) are configured with a great number of ultra-low power consumption wearable devices, which constantly monitor physiological signals of the human body and thus realize intelligent monitoring. However, the collection and transfer of human body signals consume energy, and considering the comfort demand of wearable devices, both the size and the capacity of a wearable device's battery are limited. Thus, minimizing the energy consumption of wearable devices and optimizing the BAN energy efficiency is still a challenging problem...
July 10, 2017: Sensors
https://www.readbyqxmd.com/read/28691694/context-dependent-adaptation-improves-robustness-of-myoelectric-control-for-upper-limb-prostheses
#10
Gauravkumar K Patel, Janne Mathias Hahne, Claudio Castellini, Dario Farina, Strahinja Dosen
OBJECTIVE: Dexterous upper-limb prostheses are available today to restore grasping, but an effective and reliable feed-forward control is still missing. The aim of this work was to improve the robustness and reliability of myoelectric control by using context information from sensors embedded within the prosthesis. APPROACH: We developed a context-driven myoelectric control scheme (cxMYO) that incorporates the inference of context information from proprioception (inertial measurement unit) and exteroception (force and grip aperture) sensors to modulate the outputs of myoelectric control...
July 10, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28688027/pharmacokinetics-of-fentanyl-and-its-derivatives-in-children-a-comprehensive-review
#11
REVIEW
Victoria C Ziesenitz, Janelle D Vaughns, Gilbert Koch, Gerd Mikus, Johannes N van den Anker
Fentanyl and its derivatives sufentanil, alfentanil, and remifentanil are potent opioids. A comprehensive review of the use of fentanyl and its derivatives in the pediatric population was performed using the National Library of Medicine PubMed. Studies were included if they contained original pharmacokinetic parameters or models using established routes of administration in patients younger than 18 years of age. Of 372 retrieved articles, 44 eligible pharmacokinetic studies contained data of 821 patients younger than 18 years of age, including more than 46 preterm infants, 64 full-term neonates, 115 infants/toddlers, 188 children, and 28 adolescents...
July 7, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28682837/closed-loop-and-decision-assist-guided-fluid-therapy-of-human-hemorrhage
#12
Gabriel Hundeshagen, George C Kramer, Nicole Ribeiro Marques, Michael G Salter, Aristides K Koutrouvelis, Husong Li, Daneshvari R Solanki, Alexander Indrikovs, Roger Seeton, Sheryl N Henkel, Michael P Kinsky
OBJECTIVES: We sought to evaluate the efficacy, efficiency, and physiologic consequences of automated, endpoint-directed resuscitation systems and compare them to formula-based bolus resuscitation. DESIGN: Experimental human hemorrhage and resuscitation. SETTING: Clinical Research Laboratory. SUBJECTS: Healthy volunteers. INTERVENTIONS: Subjects (n = 7) were subjected to hemorrhage and underwent a randomized fluid resuscitation scheme on separate visits 1) formula-based bolus resuscitation; 2) semiautonomous (decision assist) fluid administration; and 3) fully autonomous (closed loop) resuscitation...
July 4, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28682267/a-novel-authentication-and-key-agreement-scheme-for-implantable-medical-devices-deployment
#13
Mohammad Wazid, Ashok Kumar Das, Neeraj Kumar, Mauro Conti, Athanasios V Vasilakos
Implantable medical devices (IMDs) are man-made devices, which can be implanted in the human body to improve the functioning of various organs. The IMDs monitor and treat physiological condition of the human being (for example, monitoring of blood glucose level by insulin pump). The advancement of information and communication technology (ICT) enhances the communication capabilities of IMDs. In healthcare applications, after mutual authentication, a user (for example, doctor) can access the health data from the IMDs implanted in a patient's body...
June 29, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28668056/girsanov-reweighting-for-path-ensembles-and-markov-state-models
#14
L Donati, C Hartmann, B G Keller
The sensitivity of molecular dynamics on changes in the potential energy function plays an important role in understanding the dynamics and function of complex molecules. We present a method to obtain path ensemble averages of a perturbed dynamics from a set of paths generated by a reference dynamics. It is based on the concept of path probability measure and the Girsanov theorem, a result from stochastic analysis to estimate a change of measure of a path ensemble. Since Markov state models (MSMs) of the molecular dynamics can be formulated as a combined phase-space and path ensemble average, the method can be extended to reweight MSMs by combining it with a reweighting of the Boltzmann distribution...
June 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28668053/magnitude-of-pseudopotential-localization-errors-in-fixed-node-diffusion-quantum-monte-carlo
#15
Jaron T Krogel, P R C Kent
Growth in computational resources has lead to the application of real space diffusion quantum Monte Carlo to increasingly heavy elements. Although generally assumed to be small, we find that when using standard techniques, the pseudopotential localization error can be large, on the order of an electron volt for an isolated cerium atom. We formally show that the localization error can be reduced to zero with improvements to the Jastrow factor alone, and we define a metric of Jastrow sensitivity that may be useful in the design of pseudopotentials...
June 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28666752/dosing-of-caspofungin-based-on-a-pharmacokinetic-pharmacodynamic-index-for-the-treatment-of-invasive-fungal-infections-in-critically-ill-patients-on-continuous-venovenous-haemodiafiltration
#16
Alejandro Pérez-Pitarch, Rafael Ferriols-Lisart, Gerardo Aguilar, Carlos Ezquer-Garín, F Javier Belda, Beatriz Guglieri-López
INTRODUCTION: The objective of this study was to evaluate the efficacy of different dosages of caspofungin in the treatment of invasive candidiasis and aspergillosis, in relation to the probability of pharmacokinetic/pharmacodynamic target attainment, using modelling and Monte Carlo simulations in critically ill adult patients on continuous haemodiafltration. METHODS: Critically ill adult patients on continuous venovenous haemodiafiltration treated with caspofungin were analysed...
June 27, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28657178/1-cyclohexyl-x-methoxybenzene-derivatives-novel-psychoactive-substances-seized-on-the-internet-market-synthesis-and-in-vivo-pharmacological-studies-in-mice
#17
Anna Fantinati, Andrea Ossato, Sara Bianco, Isabella Canazza, Fabio De Giorgio, Claudio Trapella, Matteo Marti
INTRODUCTION: Among novel psychoactive substances notified to EMCDDA and Europol were 1-cyclohexyl-x-methoxybenzene stereoisomers (ortho, meta, and para). These substances share some structural characteristics with phencyclidine and tramadol. Nowadays, no information on the pharmacological and toxicological effects evoked by 1-cyclohexyl-x-methoxybenzene are reported. The aim of this study was to investigate the effect evoked by each one stereoisomer on visual stimulation, body temperature, acute thermal pain, and motor activity in mice...
May 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28656519/where-are-we-headed-with-neuromodulation-for-overactive-bladder
#18
REVIEW
Kaitlin Jaqua, Charles R Powell
Overactive bladder (OAB) affects millions of people around the world and decreases quality of life for those affected. Over the past two decades, significant advances in treatment have transformed the lives of those with OAB. Sacral neuromodulation (SNM), posterior tibial nerve stimulation (PTNS), and dorsal genital nerve stimulation are the most effective contemporary treatment modalities. New techniques and bio-sensing schemes offer promise to advance therapy beyond what is currently available. Current neuromodulation techniques do not use real-time data from the body or input from the patient...
August 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28655454/mlc-tracking-for-lung-sabr-reduces-planning-target-volumes-and-dose-to-organs-at-risk
#19
Vincent Caillet, Paul J Keall, Emma Colvill, Nicholas Hardcastle, Ricky O'Brien, Kathryn Szymura, Jeremy T Booth
PURPOSE: Assess the dosimetric impact of multi-leaf collimator (MLC) tracking and mid-ventilation (midV) planning compared with the internal target volume (ITV)-based planning approach for lung Stereotactic Ablative Body Radiotherapy (SABR). METHOD: Ten lung SABR patients originally treated with an ITV-based plan were re-planned according to MLC tracking and midV planning schemes. All plans were delivered on a linac to a motion phantom in a simulated treatment with real lung motions...
June 24, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28653595/cohort-differences-in-exercise-adherence-among-primary-care-patients-referred-for-mental-health-versus-physical-health-conditions
#20
Patrick Tobi, Philip Kemp, Elena Schmidt
Aim To compare the characteristics of mental health and physical health participants attending an exercise referral scheme (ERS) and investigate associations with their adherence to exercise. BACKGROUND: While people referred to an ERS with a mental health diagnosis have similar initial rates of uptake as physical health participants, they are more likely to drop out. Comparisons of the groups to understand their differences and how these might impact on their adherence have been limited by the typically low numbers of mental health referrals in many schemes...
June 27, 2017: Primary Health Care Research & Development
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