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https://www.readbyqxmd.com/read/28814901/prediction-of-drug-related-problems-in-diabetic-outpatients-in-a-number-of-hospitals-using-a-modeling-approach
#1
Ghaith M Al-Taani, Sayer I Al-Azzam, Karem H Alzoubi, Feras W Darwish Elhajji, Michael G Scott, Hamzah Alfahel, Mamoon A Aldeyab
OBJECTIVE: Drug-related problems (DRPs) are considered a serious, expensive, and important undesirable complication of health care. However, as current health care resources are limited, pharmacist DRP services cannot be provided to all patients. Using a modeling approach, we aimed to identify risk factors for DRPs so that patients for DRP-reduction services can be better identified. METHODS: Patients with diabetes from outpatient clinics from five key university-affiliated and public hospitals in Jordan were assessed for DRPs (drug without an indication, untreated indication, and drug efficacy problems)...
2017: Drug, Healthcare and Patient Safety
https://www.readbyqxmd.com/read/28814375/influencers-of-generic-drug-utilization-a-systematic-review
#2
REVIEW
Jennifer N Howard, Ilene Harris, Gavriella Frank, Zippora Kiptanui, Jingjing Qian, Richard Hansen
INTRODUCTION: With an increase in prescription drug spending and rising drug costs there is a need to encourage the use of generic prescription drugs. However, maximizing generic drug use is not possible without the public's positive perception and meeting their informational needs about generic drugs. Thus, improving the public's confidence in, and knowledge of generic drugs on the market is critical. The objective of this systematic review is to examine and evaluate the studies focusing on the nature and extent of key factors influencing generic drug use in the United States in order to help guide policy, education and practice interventions...
August 4, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28813502/addressing-the-challenge-of-high-priced-prescription-drugs-in-the-era-of-precision-medicine-a-systematic-review-of-drug-life-cycles-therapeutic-drug-markets-and-regulatory-frameworks
#3
Toon van der Gronde, Carin A Uyl-de Groot, Toine Pieters
CONTEXT: Recent public outcry has highlighted the rising cost of prescription drugs worldwide, which in several disease areas outpaces other health care expenditures and results in a suboptimal global availability of essential medicines. METHOD: A systematic review of Pubmed, the Financial Times, the New York Times, the Wall Street Journal and the Guardian was performed to identify articles related to the pricing of medicines. FINDINGS: Changes in drug life cycles have dramatically affected patent medicine markets, which have long been considered a self-evident and self-sustainable source of income for highly profitable drug companies...
2017: PloS One
https://www.readbyqxmd.com/read/28811088/primary-prevention-aspirin-use-in-high-risk-patients-a-pharmacist-intervention-and-comparison-of-risk-stratification-tools
#4
Scott A Coon, Amie D Brooks, Stephen E Wolff
OBJECTIVES: The objectives of this project are 1) to describe aspirin use for primary prevention in an underserved, minority population; 2) to determine the impact of a pharmacist-led intervention on the prevalence of aspirin use for primary prevention; and 3) to compare aspirin indications based on Framingham Risk Score (FRS) and atherosclerotic cardiovascular disease (ASCVD) risk score. METHODS: Men and women age 45-79 and 55-79 years, respectively, without ASCVD were screened for aspirin use...
August 12, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28811014/assessing-need-for-pharmacist-involvement-to-improve-care-coordination-for-patients-on-lai-antipsychotics-transitioning-from-hospital-to-home-a-work-system-approach
#5
Olufunmilola Abraham, Michelle N Myers, Amanda L Brothers, Jamie Montgomery, Bryan A Norman, Tanya Fabian
BACKGROUND: The use of Long-Acting Injectable (LAI) antipsychotic medications has increased for patients with Serious Mental Illness (SMI). Care coordination for this population is complex, and pharmacist involvement may improve and support long-term medication adherence and patient outcomes. OBJECTIVES: (1) Examine pharmacists' role in addressing care coordination and adherence challenges for patients taking Long-Acting Injectable (LAI) antipsychotics; and (2) explore patients' medication use experiences with LAI antipsychotics and educational needs...
September 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28807658/self-reported-participation-in-voluntary-nonprescription-syringe-sales-in-california-s-central-valley
#6
Robin A Pollini
OBJECTIVES: California Senate Bill 41 (SB41), effective January 2012, is a human immunodeficiency virus/hepatitis C virus prevention measure designed to expand syringe access among injection drug users (IDUs) by allowing pharmacies to sell syringes without a prescription. This study assesses self-reported implementation of SB41 and characterizes barriers amenable to intervention. DESIGN: Interviewer-administered survey. SETTING AND PARTICIPANTS: Fresno and Kern Counties, CA...
August 11, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/28805984/self-medication-misuse-in-the-middle-east-a-systematic-literature-review
#7
REVIEW
Malak M Khalifeh, Nicholas D Moore, Pascale R Salameh
Regulations usually distinguish between prescription-only (POM) and over-the-counter (OTC) medicines. The former requires medical prescription; the latter are available for SM of common minor or easily treated ailments. However, in the Eastern Mediterranean countries, theoretical prescription medicines can easily be purchased without a prescription, as self-medication (SM) resulting in potential misuse and unnecessary risk for patients. The magnitude of this activity is uncertain. The aim of this article, therefore, is to undertake a comprehensive review to identify the different types of medicines that can easily be purchased as SM in Middle East and recognized as misused...
August 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28795519/outcomes-costs-and-stakeholders-perspectives-associated-with-the-incorporation-of-community-pharmacy-services-into-the-national-health-insurance-system-in-thailand-a-systematic-review
#8
REVIEW
Narong Asayut, Phayom Sookaneknun, Surasak Chaiyasong, Kritsanee Saramunee
OBJECTIVES: Identify costs, outcomes and stakeholders' perspectives associated with incorporation of community pharmacy services into the Thai National Health Insurance System and their values to all stakeholders. METHODS: Using a combination of search terms, a comprehensive literature search was performed using the Thai Journal Citation Index Centre, Health System Research Institute database, PubMed and references from recent reviews. Identified studies were published between January 2000 and December 2014...
August 9, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28793078/impact-of-interventions-to-promote-the-use-of-generic-drugs-a-systematic-review
#9
Marília Cruz Guttier, Marysabel Pinto Telis Silveira, Vera Lucia Luiza, Andréa Dâmaso Bertoldi
The need to increase access to medicines, coupled with the limited acceptance of generics has sparked the search for effective interventions to promote it. This systematic review aimed to conduct a survey on interventions to promote the use of generic drugs and its impact. Randomized clinical trials, non-randomized controlled trials, controlled before-after studies and interrupted time series were included. The analysis of the impact of interventions and quality of evidence followed Cochrane's guidelines. Impact of interventions was rated from "very large" to "very small" and the quality of evidence was rated from "high" to "very low"...
August 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28791786/emergency-department-provider-perspectives-on-benzodiazepine-opioid-co-prescribing-a-qualitative-study
#10
Howard S Kim, Danielle M McCarthy, Jason A Hoppe, D Mark Courtney, Bruce L Lambert
OBJECTIVE: Benzodiazepines and opioids are prescribed simultaneously (i.e. "co-prescribed") in many clinical settings, despite guidelines advising against this practice and mounting evidence that concomitant use of both medications increases overdose risk. This study sought to characterize the contexts in which benzodiazepine-opioid co-prescribing occurs and providers' reasons for co-prescribing. METHODS: We conducted focus groups with ED providers (resident and attending physicians, advanced practice providers, and pharmacists) from three hospitals using semi-structured interviews to elicit perspectives on benzodiazepine-opioid co-prescribing...
August 9, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28789606/-pharming-out-support-a-promising-approach-to-integrating-clinical-pharmacists-into-established-primary-care-medical-home-practices
#11
Kimberly D Brunisholz, Jeff Olson, Jonathan W Anderson, Emily Hays, Peggy M Tilbury, Bradley Winter, Josh Rickard, Sharon Hamilton, Gregory Parkin
Objective Embedding clinical pharmacists into ambulatory care settings needs to be assessed in the context of established medical home models. Methods A retrospective, observational study examined the effectiveness of the Intermountain Healthcare Collaborative Pharmacist Support Services (CPSS) program from 2012-2015 among adult patients diagnosed with diabetes mellitus (DM) and/or high blood pressure (HBP). Patients who attended this program were considered the intervention (CPSS) cohort. These patients were matched using propensity scores with a reference group (no-CPSS cohort) to determine the effect of achieving disease management goals and time to achievement...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28783816/association-of-dissemination-of-an-educational-communication-tool-with-docusate-administration
#12
Darren Pasay, Micheal Guirguis, Rhonda Shkrobot, Jeremy Slobodan, Lauren Bresee
Importance: A clear message and call to action can affect the use of a medication with limited efficacy. Objectives: To assess the association of the dissemination of an educational document about the lack of efficacy of docusate with docusate administration and whether changing docusate administration was associated with a change in administration of comparable laxatives. Design, Setting, and Participants: In this quasi-experimental, pre-post study of all acute care and continuing care facilities serviced by Alberta Health Services in Alberta, Canada, an interrupted time series analysis was performed to examine the association of an educational communication tool with docusate administration from June 1, 2014, through May 31, 2016...
August 7, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28781821/usefulness-of-a-pharmacist-outpatient-service-for-s-1-adjuvant-chemotherapy-in-patients-with-gastric-cancer
#13
Michio Kimura, Makiko Go, Mina Iwai, Eiseki Usami, Hitomi Teramachi, Tomoaki Yoshimura
S-1 adjuvant chemotherapy is an outpatient treatment for gastric cancer. To evaluate the role of the pharmacist outpatient service in increasing medication adherence and reducing adverse events associated with S-1, the present study retrospectively analyzed prescription recommendations from pharmacists to physicians and the persistence rate of S-1 adjuvant chemotherapy use in patients with gastric cancer. A total of 40 subjects who utilized the pharmacist outpatient service between November 2014 and March 2016 comprised the pharmacist group; and 94 patients who underwent S-1 adjuvant chemotherapy for gastric cancer between September 2012 and October 2014, but not as pharmacist outpatients, comprised the control group...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28780910/drug-related-problems-in-community-dwelling-primary-care-patients-screened-positive-for-dementia
#14
D Wucherer, J R Thyrian, T Eichler, J Hertel, I Kilimann, S Richter, B Michalowsky, I Zwingmann, A Dreier-Wolfgramm, C A Ritter, S Teipel, W Hoffmann
BACKGROUND: Older people have a higher risk of drug-related problems (DRPs). However, little is known about the prevalence of DRPs in community-dwelling people who screened positive for dementia. Our study aimed to determine (1) the prevalence and types of DRPs and (2) the socio-demographic and clinical variables associated with DRPs in people screened positive for dementia in primary care. METHODS: The Dementia: life- and person-centered help in Mecklenburg-Western Pomerania (DelpHi-MV) study is a general practitioner (GP)-based cluster-randomized controlled intervention study to implement and evaluate an innovative concept of collaborative dementia care management in the primary care setting in Germany...
August 7, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28766816/improving-adherence-to-multiple-medications-in-older-people-in-primary-care-selecting-intervention-components-to-address-patient-reported-barriers-and-facilitators
#15
Deborah E Patton, Cathal A Cadogan, Cristín Ryan, Jill J Francis, Gerard J Gormley, Peter Passmore, Ngaire Kerse, Carmel M Hughes
BACKGROUND: Medication adherence is vital to ensuring optimal patient outcomes, particularly amongst multimorbid older people prescribed multiple medications. Interventions targeting adherence often lack a theoretical underpinning and this may impact on effectiveness. The theoretical domains framework (TDF) of behaviour can aid intervention development by systematically identifying key determinants of medication adherence. OBJECTIVES: This study aimed to (i) identify determinants (barriers, facilitators) of adherence to multiple medications from older people's perspectives; (ii) identify key domains to target for behaviour change; and (iii) map key domains to intervention components [behaviour change techniques (BCTs)] that could be delivered in an intervention by community pharmacists...
August 1, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28765104/a-technological-innovation-to-reduce-prescribing-errors-based-on-implementation-intentions-the-acceptability-and-feasibility-of-myprescribe
#16
Chris Keyworth, Jo Hart, Hong Thoong, Jane Ferguson, Mary Tully
BACKGROUND: Although prescribing of medication in hospitals is rarely an error-free process, prescribers receive little feedback on their mistakes and ways to change future practices. Audit and feedback interventions may be an effective approach to modifying the clinical practice of health professionals, but these may pose logistical challenges when used in hospitals. Moreover, such interventions are often labor intensive. Consequently, there is a need to develop effective and innovative interventions to overcome these challenges and to improve the delivery of feedback on prescribing...
August 1, 2017: JMIR Human Factors
https://www.readbyqxmd.com/read/28764191/knowledge-and-perception-about-pharmacovigilance-among-pharmacy-students-of-universities-in-sana-a-yemen
#17
Gamil Qasem Othman, Mohamed Izham Mohamed Ibrahim, Mohammed Alshakka, Mukhtar Ansari, Farouk Al-Qadasi, Abdulsalam M Halboup
INTRODUCTION: Pharmacists in community or hospital setting play a key role in reporting Adverse Drug Reaction (ADRs) during practice. Under reporting is considered as a profession malpractice worldwide. AIM: To determine the level of knowledge and perception about phramacovigilance and ADRs reporting among final year pharmacy students of Universities in Sana'a Yemen. MATERIALS AND METHODS: A cross-sectional study design was conducted among 385 final year pharmacy students...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28760311/-targeted-pharmacist-led-medication-order-review-in-hospital-assessment-of-a-selection-method-for-drug-prescriptions
#18
C Jarre, J Bouchet, M Hellot-Guersing, A-S Leromain, C Derharoutunian, A Gadot, R Roubille
OBJECTIVES: The aim of this study was to assess a selection method for drug prescriptions developed at the hospital level that allows to target pharmacist-led medication order review for at-risk patients and drugs. METHODS: A one-month study has been conducted on all targeted medication orders in 19 care units. Selection criteria have been identified: biological criteria, alert medications and drug interactions. Pharmacists' interventions proposed during medication order review were listed and the possible links to the selection criteria were determined...
July 28, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28756965/drug-related-problems-in-geriatric-rehabilitation-patients-after-discharge-a-prevalence-analysis-and-clinical-case-scenario-based-pilot-study
#19
Johanna Freyer, Lucie Hueter, Lysann Kasprick, Thomas Frese, Ralf Sultzer, Susanne Schiek, Thilo Bertsche
BACKGROUND: Geriatric patients bear a high risk for having drug-related problems (DRPs). Transitions of care are especially susceptible to these DRPs. OBJECTIVE: To highlight the prevalence of DRPs in geriatric patients' post-discharge medication lists and to assess physicians' ability to identify DRPs by using clinical case scenarios. METHODS: A sequential prospective mixed-method study was performed. In a DRP prevalence analysis, an expert panel of clinical pharmacists analyzed DRPs in post-discharge medication lists of long-term hospitalized patients from a German inpatient geriatric rehabilitation center...
July 25, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28743529/implementation-of-a-patient-navigator-program-to-reduce-30-day-heart-failure-readmission-rate
#20
REVIEW
Katherine E Di Palo, Khusbu Patel, Manaf Assafin, Ileana L Piña
With increasing awareness to provide personalized care our institution applied the American College of Cardiology (ACC) Patient Navigator Program to identify hospitalized heart failure (HF) patients and improve transitions and outcomes. Utilizing a Navigator Team (NT) composed of a nurse and clinical pharmacist, we delivered evidenced-based interventions and hypothesized this approach would improve identification of HF inpatients and reduce the 30-day all-cause readmission rate. Patients were followed from admission to discharge and received at least one intervention, tailored to the patient's health literacy and social needs...
July 22, 2017: Progress in Cardiovascular Diseases
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