Read by QxMD icon Read


Rishabh Verma, Paula Matich, David Symmons, Venkat Vangaveti
Antiemetics are medications that are frequently used in the pre-hospital setting. However, recent evidence indicates that antiemetics are ineffective in reducing undifferentiated nausea scores and vomiting rates. The aim of this study is to evaluate the efficacy and safety of antiemetics administered in the pre-hospital setting. This is a systematic review employing PRISMA guidelines of seven studies selected that included randomised controlled trials and prospective studies, investigating the use of antiemetics in the pre-hospital setting...
August 14, 2018: Emergency Medicine Australasia: EMA
William Eggleston, Ross W Sullivan, Lauren Pacelli, Christine Podolak, Michael Keenan, Susan Wojcik
BACKGROUND AND AIMS: Expanded access to naloxone has been identified as a key intervention for reducing opioid related morbidity and mortality. It is not known which naloxone device will result in rapid, successful administration when administered by community members. The aims of this study were to estimate and compare 1) the rate of successful administration and 2) time to successful administration for single step nasal spray, multi-step atomized nasal spray, and intramuscular simulated naloxone by community members...
August 14, 2018: Addiction
Tuncay Küme, Ferzane Mercan, Hatice Topsakal, Çiğdem Karakükcü, Mehmet Şeneş, Aslı Pınar, Mukaddes Gürler, Hakan Kalafat, Belgin Ünal, Alain G Verstraete, Yeşim Hamurtekin, Ahmet Aydınlı, Yasemin Şenol, Muhammed Ertuğrul Eğin, Alper Cihan, Elif Güler Kazancı, Eyüp Gümüş
BACKGROUND: The aim of this study is to assess the results of inspections in the last 3 years on drug abuse testing in medical laboratories according to the last regulations in Turkey. MATERIALS AND METHODS: The on-site inspections of medical laboratories for drugs abuse testing performed in Alcohol and Drug Addiction Treatment Centers in 2014-2016 are described, and laboratory processes and performance were evaluated. The performance of 35 laboratories in 2014, 62 laboratories in 2015, 94 laboratories in 2016 were scored as the sum of the scores for all answers in the inspection form...
August 14, 2018: Drug Testing and Analysis
Florentine Schreiner, Gurpreet Anand, Felix Beuschlein
Endocrine active adrenal tumors are associated with a relevant risk of complications during surgery, either due to direct hemodynamic effects of the hormone excess or due to hormone related comorbidities. Over the last decades, careful preoperative evaluation and improved peri-interventional medical management of affected patients has resulted in a significant reduction of perioperative complications. In addition, improvement in anesthesia and surgical techniques with the feasibility of laparoscopic adrenalectomy have contributed to reduce morbidity...
August 14, 2018: Experimental and Clinical Endocrinology & Diabetes
Hilmi Erdem Sumbul, Ayse Selcan Koc
BACKGROUND: We aimed to determine whether there is an increase in aortic intima-media thickness values measured from the abdominal aorta in addition to the traditional carotid intima-media thickness in patients with primary hyperparathyroidism and to determine the parameters closely related to aortic intima-media thickness. METHODS: This perspective study included 65 primary hyperparathyroidism patients and 30 healthy-controls. Routine laboratory tests for the diagnosis of hyperparathyroidism and vascular ultrasound examinations were performed...
August 14, 2018: Experimental and Clinical Endocrinology & Diabetes
Erin Rothwell, Erin Johnson, Bob Wong, Nancy C Rose, Gwen Latendresse, Roger Altizer, Jose Zagal, Marcela Smid, Abby Watson, Jeffrey R Botkin
PURPOSE:  This project developed and evaluated the efficacy of a game decision aid among pregnant women about prenatal screening in a randomized controlled study. METHOD:  Participants were recruited from an obstetric clinic of an academic urban medical center and randomized ( n  = 73) to one of two study groups: the control group ( n  = 39) that used a brochure or the intervention group ( n  = 34) that also used a game decision aid. RESULT:  Participants who played the game had higher knowledge scores ( m  = 21...
August 14, 2018: American Journal of Perinatology
Angelo Antonini, Wolfgang H Jost
Development of motor fluctuations and dyskinesia characterizes the transition from the early to the advanced Parkinson stage. Current oral therapeutic strategies aim at increasing the number of levodopa administrations and extending its benefit by the association of enzyme blockers (MAO- and COMT-inhibitors) and dopamine agonists. However, as disease progresses, mobility becomes progressively dependent on levodopa absorption and plasma bioavailability, resulting in disabling motor complications. If patients continue to experience off time with functional impact on activities of daily living after best oral medication adjustments, implementation of infusion therapies with apomorphine or levodopa, and surgical techniques should be considered...
August 14, 2018: Fortschritte der Neurologie-Psychiatrie
Christian Núñez, Christian Stephan-Otto, Judith Usall, Miquel Bioque, Antonio Lobo, Ana González-Pinto, Laura Pina-Camacho, Eduard Vieta, Josefina Castro-Fornieles, Roberto Rodriguez-Jimenez, Anna Butjosa, Joost Janssen, Bibiana Cabrera, Mara Parellada, Miquel Bernardo
Although there is recent evidence that cells from the peripheral immune system can gain access to the central nervous system in certain conditions such as multiple sclerosis, their role has not been assessed in psychosis. Here, we aimed to explore whether blood cell count was associated with brain volume and/or clinical symptomatology. A total of 218 participants (137 first-episode psychosis patients [FEP] and 81 healthy controls [HC]) were included in the study. For each participant, a T1 structural image was acquired, from which brain tissue volumes were calculated...
August 10, 2018: Schizophrenia Bulletin
Bente Mertz Nørgård, Bjarne Magnussen, Jens Fedder, Punyanganie S de Silva, Sonja Wehberg, Sonia Friedman
Backgroud: Women with inflammatory bowel disease (IBD) might have an increased tendency to choose an elective abortion due to a fear that their fetus could be harmed by use of medications, disease flares during pregnancy, or for genetic reasons. We examined the risk of elective abortions in women with ulcerative colitis (UC) and Crohn's disease (CD) compared with women without IBD. Methods: This nationwide cohort study, based on Danish health registries, comprises all registered pregnancies from 1996 through 2015...
August 10, 2018: Inflammatory Bowel Diseases
Gianfranco Frojo, Aaron Dotson, Kara Christopher, Sumesh Kaswan, Herluf Lund
Background: Anesthesia for elective ambulatory procedures must provide appropriate pain control while minimizing perioperative risk. Local anesthesia in combination with oral sedation provides a safe office-based method of anesthesia for rhytidectomy. Objectives: The purpose of this analysis was to identify the incidence of traditional outcome parameters in ambulatory rhytidectomy performed with local anesthesia and oral sedation. Methods: A retrospective chart review was performed on all patients who underwent office-based rhytidectomy under local anesthesia with oral sedation from February 2011 to May 2017...
August 13, 2018: Aesthetic Surgery Journal
Alejandro Iregui, Karen Ha, Katharine Meleney, David Landman, John Quale
Objectives: Carbapenemase-producing Enterobacteriaceae are important nosocomial pathogens in many medical centres. Surveillance is needed to track trends and detect emergence of new carbapenemases. Methods: Single-patient isolates of Enterobacteriaceae were gathered from seven medical centres in New York City over a 3 month period in 2017. Susceptibility testing was performed and isolates were screened for selected carbapenemases. Additional isolates referred to our laboratory in 2018 were also tested...
August 10, 2018: Journal of Antimicrobial Chemotherapy
Andrew D Haddow
No abstract text is available yet for this article.
August 11, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Danielle E McCarthy, Mark Versella
Introduction: Non-adherence to pharmacotherapies complicates studies of comparative pharmacotherapy effectiveness. Modeling adherence and abstinence simultaneously may facilitate analysis of both treatment acceptability and effectiveness. Methods: Secondary analyses of a three-arm randomized comparative trial of nicotine patch, varenicline, and combination nicotine patch and lozenge among adult daily smokers (N=1086) were conducted. Adherence rates collected via interactive voice response systems during the first 27 days of quitting were compared across treatment conditions...
August 9, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
Kirill Kosilov, Sergay Loparev, Irina Kuzina, Liliya Kosilova, Alexandra Prokofyeva
Objective: To study the effect of socioeconomic status (SES) on health-related quality of life (HRQoL) among persons with overactive bladder (OAB). Design: A randomized HRQoL study was conducted from the year 2014 until the year 2016 based on the OAB pathology department of the regional clinical diagnostics center. Setting: The medical institutions where the study was conducted had outpatient care. Participants: The simple response frequency was 81%...
August 11, 2018: International Journal for Quality in Health Care
Michael Asamoah-Boaheng, Eric Y Tenkorang, Osei Sarfo-Kantanka
Background: Type 2 diabetes affects an increasing number of Ghanaians. The timing of the onset of diabetes is linked to several other co-morbid conditions, yet no study has examined the timing of the onset of type 2 diabetes in Ghana. Methods: To fill this gap in the literature, this study applied logit models to data extracted from the medical records at the Diabetes Clinic of the Komfo Anokye Teaching Hospital in Kumasi, Ghana. Gender-specific models were also estimated...
August 11, 2018: International Health
Chuan-Chia Chang, Nian-Sheng Tzeng, Che-Yi Chao, Chin-Bin Yeh, Hsin-An Chang
Background: The efficacy of fronto-temporal transcranial direct current stimulation (tDCS) in treating auditory verbal hallucinations (AVHs) and other psychopathological symptoms of schizophrenia patients has been examined in a small number of clinical trials with limited sample sizes, but the results are mixed. Fronto-temporal tDCS has also been demonstrated to enhance patients' insight into their mental illness in an open-label pilot study. The current investigation aimed to investigate the therapeutic effects of fronto-temporal tDCS on the severity of AVHs, other schizophrenia symptoms and insight in a large double blind, randomized, sham-controlled trial...
August 9, 2018: International Journal of Neuropsychopharmacology
Thomas Martens, Martin Kostolny, Helen Spencer, Nagarajan Muthialu
Pulmonary arterial hypertension after arterial switch operation for transposition of the great arteries is rare. Lung transplantation can be the last option in cases of failed medical therapy. We report 2 paediatric patients who underwent lung transplantation for this indication. Altered hilar anatomy, mediastinal adhesions and haemostatic control represent the main technical challenges. Volume-reduction surgery is sometimes necessary to address altered cardiopulmonary relationships while expanding the donor pool...
August 9, 2018: Interactive Cardiovascular and Thoracic Surgery
S Mellinger, D Dias, N Flores, A Palavecino, G Vigo, D Burgos, F Tomas, I Rollan, G Herrera, J Floridia, C Furlan, F Frissia, A Aleman, J Perez Frías, J Casali, M Burgos
INTRODUCTION: Multiple Sclerosis (MS) is one of the leading causes of disability in young adults. Its prevalence varies according to different countries. In Argentina there is a wide heterogeneity regarding data published in different areas of the country. Prevalence established in most studies is 17 cases per 100,000 inhabitants; however, most of the available data comes from studies that took place in Buenos Aires. There is little or no information from other provinces, especially from Northwest of Argentina (NOA), where there are no studies of the disease prevalence...
July 31, 2018: Multiple Sclerosis and related Disorders
K Milton, J Chau, B McGill, A Bauman
OBJECTIVES: The media is a substantial vehicle for conveying public health messages to the public. This study examined the extent to which the publication of special issues in a high-impact medical journal in 2012 and 2016 generated media interest in physical activity and health in the UK and explored the main issues that were reported. STUDY DESIGN: This is a systematic narrative review of print media. METHODS: Relevant print news articles were identified by searching Factiva and Google News...
August 11, 2018: Public Health
Khalid Eljaaly, Samah Alshehri, Sandipan Bhattacharjee, Jaffar A Al-Tawfiq, Asad E Patanwala
OBJECTIVE: Antimicrobial agents are commonly used in ambulatory care settings. Our objective was to examine national-level patterns of contraindications between oral antibacterial or antifungal agents and patients' other oral medications in the U.S ambulatory care setting. METHODS: This cross-sectional study included multiple year pooled data (2003-2011) from the National Ambulatory Medical Care Survey (NAMCS) and the National Hospital Ambulatory Medical Care Survey (NHAMCS Outpatient Department)...
August 11, 2018: Clinical Microbiology and Infection
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"