keyword
https://read.qxmd.com/read/38512368/the-predictive-value-of-systemic-inflammatory-markers-in-902-patients-with-tunneled-hemodialysis-catheter
#21
JOURNAL ARTICLE
Melis Baykara Ulusan, Emine Meltem, Ilhan Nahit Mutlu, Kivilcim Ulusan
AIM: This study aimed to assess the predictive role of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and mean platelet volume, on catheter survival in chronic hemodialysis patients, analyzing both infectious and non-infectious complications. METHODS: A retrospective analysis encompassed 1279 tunneled catheter insertion procedures involving 902 patients between March 2014 and October 2018. Patients were categorized into two main groups: (i) initial placement and (ii) exchange...
March 21, 2024: Journal of Nephrology
https://read.qxmd.com/read/38512367/donor-transmitted-cystinuria-in-a-renal-transplant-recipient
#22
JOURNAL ARTICLE
Prathap K Simhadri, Pradeep K Vaitla, Rachana Marathi, Abdul Khan
Cystinuria is an autosomal recessive disorder associated with defective proximal tubular reabsorption of divalent amino acids. It leads to increased cystine, ornithine, lysine, and arginine excretion in the urine. Cystine is insoluble in physiological pH, and cystinuria leads to crystalluria and nephrolithiasis. We present a case of acquired cystinuria in a renal transplant recipient, that is, to the best of our knowledge, the first case of acquired cystinuria ever documented in the literature.
March 21, 2024: Journal of Nephrology
https://read.qxmd.com/read/38507633/investigation-of-igg-titers-in-hemodialysis-patients-and-controls-following-administration-of-the-covid-19-vaccine
#23
JOURNAL ARTICLE
Manizheh Jozpanahi, Roghayeh Jafari, Mohammad Moharrer, Pouria Mahmoudi, Seyedeh Pegah Saeed, Hosein Dinmohammadi
INTRODUCTION: End-Stage Renal Disease (ESRD) patients necessitate dialysis when kidney transplantation is not feasible. Hemodialysis patients exhibit higher mortality rates compared to the general population due to uremia and an increased burden of comorbidities. In this vulnerable population, defective innate and adaptive immunity contribute to infectious diseases being a leading cause of hospitalization and mortality. Given the COVID-19 pandemic and the potential for a diminished antibody response to the COVID-19 vaccine among dialysis patients, this study aimed to measure IgG antibody titers in this patient group following COVID-19 vaccination and compare them to healthy individuals...
March 18, 2024: International Tinnitus Journal
https://read.qxmd.com/read/38496140/refractory-ischemic-priapism-following-hemodialysis
#24
Abdalhai Alshoubi, Farris Al-Qawasmi
Priapism, characterized by prolonged and painful penile erection, is a rare urological emergency with diverse etiologies. We present a case of refractory ischemic priapism following hemodialysis in a 57-year-old male with a history of type II diabetes mellitus, hypertension, and end-stage renal disease. Despite standard conservative management, the patient's condition persisted, necessitating penile distal shunting through an intracorporeal dilatation plus Al-Ghorab corporoglandular shunt. Blood gas analysis of corpus cavernosum blood revealed severe acidosis and hypoxemia, emphasizing the systemic impact of ischemic priapism...
February 2024: Curēus
https://read.qxmd.com/read/38494779/unusual-urothelial-tumors-and-refractory-uremia-due-to-balkan-endemic-nephropathy-a-case-report
#25
REVIEW
Gevorg Arabyan, Raphi Hambartzhumian, Anthony Lim, Marrey Quizon, Julia Oberndorf, Michael A Sanford
Balkan endemic nephropathy (BEN) is a rare progressive chronic renal disease found in residents living along the Balkan peninsula. We present a 92-year-old female who complained initially of cardio-respiratory symptoms and was found to have an acute hypoxemic respiratory failure with hypervolemia. The patient underwent computed tomography imaging and was found to have bilateral pleural effusions and moderate left-sided renal atrophy with left-sided hydronephrosis. The patient underwent diuresis for fluid overload and was treated with broad-spectrum antibiotics for hospital-acquired pneumonia...
2024: Journal of Investigative Medicine High Impact Case Reports
https://read.qxmd.com/read/38493318/transplant-renal-artery-stenosis-a-case-report-and-literature-review
#26
JOURNAL ARTICLE
Nasser Simforoosh, Amirhossein Nayebzade, Meisam Ghaedi
Transplant renal artery stenosis is the most common vascular complication that turns out following kidney transplantation and can lead to graft dysfunction and even its loss. The present report, describes A patient with end-stage renal disease who underwent living related renal transplantation. He had oliguria and creatinine rise in the post-operative course but all doppler ultrasonography (DUS) during the 2 months post-operation for the renal graft showed a normal mean resistive index in the graft renal artery...
March 17, 2024: Urology Journal
https://read.qxmd.com/read/38492684/the-effect-of-niacinamide-supplementation-on-phosphate-concentrations-in-dutch-dialysis-patients-a-randomised-crossover-trial
#27
JOURNAL ARTICLE
Lara Schepers, Inez Jans, Gerda K Pot, Arend-Jan Smilde, Julia M Hofstra, Nicole M de Roos
OBJECTIVE: Hyperphosphatemia is a common complication in patients with kidney failure, despite the use of phosphate binders (PBs). Vitamin B3, either in the form of niacin or niacinamide (NAM), shows potential as "add-on" treatment to reduce serum phosphate concentrations in this population. NAM seems to lack many of the side-effects that are observed with niacin. The aim of this study was to investigate whether NAM is an effective and acceptable treatment in reducing serum phosphate concentrations in patients with kidney failure...
March 14, 2024: Journal of Renal Nutrition
https://read.qxmd.com/read/38492168/residents-satisfaction-and-suggestions-to-improve-nephrology-residency-in-italy-and-comparison-with-the-organization-in-other-european-countries
#28
JOURNAL ARTICLE
Adolfo Marco Perrotta, Silverio Rotondi, Maria Amicone, Irene Cirella, Rossella Siligato, Simone Fontana, Carmen Sivo, Anna Rita Vestri, Giovanni Gambaro, Giorgina Barbara Piccoli, Sandro Mazzaferro
BACKGROUND: In Italy, nephrology residency is available in twenty-one nephrology schools, each with its own strengths and weaknesses. The present study is aimed at exploring the residents' satisfaction with their training programs. METHODS: Between April 20th and May 19th, 2021, a questionnaire on residency satisfaction consisting of 49 items was sent to 586 residents and 175 recently certified specialists (qualified to practice as nephrologists in 2019 and 2020), with a response rate of 81% and 51%, respectively...
March 16, 2024: Journal of Nephrology
https://read.qxmd.com/read/38490516/role-of-peritoneal-equilibration-test-in-assessing-folate-transport-during-peritoneal-dialysis
#29
JOURNAL ARTICLE
Yu-Ling Lin, Yi-Che Lee, Chih-Chung Lee, Mei-Hsuan Wu
BACKGROUND: Low plasma folate levels have been reported in patients undergoing hemodialysis and peritoneal dialysis (PD) in clinical studies. However, folate transport has never been mentioned as a factor contributing to low plasma folate levels in patients undergoing PD. The peritoneal equilibrium test (PET) assesses the plasma creatinine level and glucose transport abilities. This study aimed to evaluate the association between plasma folate levels and folate transport during PD based on PET grades...
March 13, 2024: Journal of Renal Nutrition
https://read.qxmd.com/read/38490032/vaginal-peritoneum-fistula-through-pouch-of-douglas-during-peritoneal-dialysis-case-report-and-literature-review
#30
Francisco Aguilar-Espinosa, José Armando Álvarez-Maldonado, Luis Andrés Isaías-Velazquez, Jorge Alberto Martínez-Mejía, Oscar Daniel Mejía-Sierra, Erika Diana Barba-Jaramillo
INTRODUCTION: Peritoneal dialysis is the preferred approach for kidney replacement therapy. A peritoneal-vaginal fistula is a rare complication associated with peritoneal dialysis. CASE PRESENTATION: A 69-year-old woman with a history of type two diabetes and systemic arterial hypertension for twenty years is scheduled to undergo the surgical placement of a Tenckoff catheter to begin renal replacement therapy. After having thirty dialysis sessions, she was discharged to continue therapy at home...
March 11, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38489957/quantification-of-endogenous-angiotensin-1-10-1-9-1-8-1-7-and-1-5-in-human-plasma-using-micro-uhplc-ms-ms-outlining-the-importance-of-the-pre-analytics-for-reliable-results
#31
JOURNAL ARTICLE
Jonathan Maurer, Anke de Groot, Léon Martin, Eric Grouzmann, Grégoire Wuerzner, Philippe J Eugster
Angiotensin peptides (ANGs) play a central role in the renin-angiotensin-aldosterone system, rendering them interesting biomarkers associated with hypertension. Precise quantification of circulating ANGs holds the potential to assess the activity of angiotensin-converting enzyme (ACE), a key protease targeted by widely prescribed drugs, namely ACE inhibitors. This ability could pave the way for personalised medicine, offering insights into the prescription of inhibitors targeting either the proteases or the receptors within the system...
March 9, 2024: Journal of Pharmaceutical and Biomedical Analysis
https://read.qxmd.com/read/38489143/clinical-effect-of-roxadustat-vs-erythropoietin-in-non-dialysis-ckd-with-diabetes-a-single-center-propensity-score-matching-analysis
#32
JOURNAL ARTICLE
Chen Jin, Yan Ren, Minmin Wang, Xiao Hu, Yiwei Shang, Yiwen Li, Bin Zhu, Qiang He, Lina Shao
PURPOSE: Renal anemia is a common complication of chronic kidney disease. Currently, recombinant human erythropoietin and roxadustat are the main treatments. In China, diabetic kidney disease is the primary cause of chronic kidney disease. However, high-quality evidence on the efficacy of roxadustat in patients with non-dialysis-dependent chronic kidney disease and diabetes mellitus is scarce. This study aimed to assess the clinical effect of roxadustat in such patients. METHODS: Patients with non-dialysis-dependent anemia and diabetes mellitus who received roxadustat or recombinant human erythropoietin for ≥ 4 weeks were enrolled...
March 15, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38482569/long-term-mortality-in-patients-with-end-stage-renal-disease-undergoing-hemodialysis-and-peritoneal-dialysis-a-propensity-score-matching-retrospective-study
#33
JOURNAL ARTICLE
Pengjie Zhang, Liru Xun, Nan Bao, Ding Tong, Bin Duan, Du Peng
BACKGROUND: Hemodialysis (HD) and peritoneal dialysis (PD) are effective ways to treat end-stage renal disease (ERSD). This study aimed to investigate the differences in survival and the factors that influence it in patients with end-stage renal disease treated with HD or PD. METHODS: We retrospectively analyzed factors related to all-cause death with renal replacement therapy and compared the long-term mortality between HD and PD strategies in patients with ESRD who started HD or PD treatment in our renal HD center between January 1, 2008, and December 1, 2021...
December 2024: Renal Failure
https://read.qxmd.com/read/38470035/collaborative-approach-toward-transplant-candidacy-for-obese-end-stage-renal-disease-patients
#34
JOURNAL ARTICLE
Shauna Levy, Abdallah Attia, Mahmoud Omar, Nicole Langford, Adarsh Vijay, Hoonbae Jeon, Carlos Galvani, Mary T Killackey, Anil S Paramesh
BACKGROUND: An elevated Body Mass Index (BMI) is a major cause of transplant preclusion for patients with End Stage Renal Disease (ESRD). This phenomenon exacerbates existing socioeconomic and racial disparities and increases the economic burden of maintaining patients on dialysis. Metabolic Bariatric Surgery (MBS) in such patients is not widely available. Our center created a collaborative program to undergo weight loss surgery before obtaining a kidney transplant. STUDY DESIGN: We studied the outcomes of these patients post MBS and transplant surgery...
March 12, 2024: Journal of the American College of Surgeons
https://read.qxmd.com/read/38463060/prevalence-and-clinical-characteristics-of-hyperuricemia-among-patients-with-chronic-kidney-disease-under-haemodialysis-in-a-tertiary-care-center-a-cross-sectional-study
#35
JOURNAL ARTICLE
Ayush Mohan Bhattarai, Shekhar Gurung, Ayush Adhikari, Saurab Karki, Bishnu Deep Pathak, Bishal Regmi, Manoj Khadka, Gopal Kumar Yadav, Somika Basnet
BACKGROUND: Hyperuricemia is common in chronic kidney disease patients. This study aimed to investigate the prevalence and clinical characteristics of hyperuricemia in patients with chronic kidney disease undergoing haemodialysis. MATERIALS AND METHODS: This cross-sectional study was conducted among 104 patients with chronic kidney disease who visited the haemodialysis unit of a tertiary centre hospital from 11 September 2022, to 11 November 2022. A convenience sampling technique was used...
March 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38450843/the-effect-of-primary-renal-disease-upon-outcomes-after-renal-transplant
#36
JOURNAL ARTICLE
Shona Garland, Kairi Pullerits, Chukwuma A Chukwu, Rajkumar Chinnadurai, Rachel Middleton, Philip A Kalra
BACKGROUND: This study investigated whether nature of primary renal disease affects clinical outcomes after renal transplantation at a single center in the United Kingdom. METHODS: This was a retrospective cohort study of 961 renal transplant recipients followed up at a large renal center from 2000 to 2020. Separation of diseases responsible for end-stage kidney disease included glomerulonephritis, diabetic kidney disease, hypertensive nephropathy, autosomal dominant polycystic kidney disease, unknown cause, other causes and chronic pyelonephritis...
March 2024: Clinical Transplantation
https://read.qxmd.com/read/38448815/relationship-between-serum-phosphorus-and-mortality-in-non-dialysis-chronic-kidney-disease-patients-evidence-from-nhanes-2001-2018
#37
JOURNAL ARTICLE
Zhongcheng Fan, Rugang Li, Miaoxia Pan, Yangyang Jiang, Ying Li, Li Liu, Yang Li
BACKGROUND: Hyperphosphatemia is common in chronic kidney disease (CKD), associated with higher mortality in dialysis patients. Its impact in non-dialysis patients, especially those with preserved kidney function, remains uncertain. METHODS: A prospective cohort study was conducted using data from the National Health and Nutrition Examination Survey (2001-2008). Serum phosphorus was analyzed as a continuous variable, or categorized into three groups: < 3...
March 6, 2024: BMC Nephrology
https://read.qxmd.com/read/38448299/association-between-cyp4a11-and-ephx2-genetic-polymorphisms-and-chronic-kidney-disease-progression-in-hypertensive-patients
#38
JOURNAL ARTICLE
Miguel A Suárez-Santisteban, Gracia Santos-Díaz, Vanesa García-Bernalt, Ana M Pérez-Pico, Esther Mingorance, Raquel Mayordomo, Pedro Dorado
BACKGROUND: There are evidence indicating that some metabolites of arachidonic acid produced by cytochromes P450 (CYP) and epoxide hydroxylase (EPHX2), such as hydroxyeicosatetraenoic acids (HETEs), epoxyeicosatrienoic acids (EETs) or dihydroxyeicosatrienoic acids (DHETEs), play an important role in blood pressure regulation and they could contribute to the development of hypertension (HT) and kidney damage. Therefore, the main aim of the study was to evaluate whether the genetic polymorphisms of CYP2C8, CYP2C9, CYP2J2, CYP4F2, CYP4F11 and EPHX2, responsible for the formation of HETEs, EETs and DHETEs, are related to the progression of impaired renal function in a group of patients with hypertension...
March 5, 2024: Nefrología
https://read.qxmd.com/read/38446386/kidney-transplants-from-elderly-donors-what-we-have-learned-20%C3%A2-years-after-the-crystal-city-consensus-criteria-meeting
#39
REVIEW
Alberto Mella, Ruggero Calvetti, Antonella Barreca, Giovanni Congiu, Luigi Biancone
Based on the current projection of the general population and the combined increase in end-stage kidney disease with age, the number of elderly donors and recipients is increasing, raising crucial questions about how to minimize the discard rate of organs from elderly donors and improve graft and patient outcomes. In 2002, extended criteria donors were the focus of a meeting in Crystal City (VA, USA), with a goal of maximizing the use of organs from deceased donors. Since then, extended criteria donors have progressively contributed to a large number of transplanted grafts worldwide, posing specific issues for allocation systems, recipient management, and therapeutic approaches...
March 6, 2024: Journal of Nephrology
https://read.qxmd.com/read/38446385/physical-activity-and-exercise-programs-for-kidney-patients-an-italian-survey-of-nephrology-centres
#40
JOURNAL ARTICLE
Francesca Bulighin, Filippo Aucella, Vincenzo Bellizzi, Adamasco Cupisti, Teresa Faga, Giovanni Gambaro, Giuseppe Regolisti, Alda Storari, Alessandro Capitanini, Yuri Battaglia
BACKGROUND: Data on exercise activities in place, and on the interest for developing them in Nephrology Services in Italy is limited. To address this gap, we carried out this cross-sectional study to investigate the status of physical activity and exercise programs available in Italian Nephrology Centres. Additionally, research priorities on this topic were examined. METHODS: We developed a 14-item electronic survey, which consisted of multiple-choice questions covering exercise training programs, physical assessment, barriers to exercise practice and to exercise programs, exercise and physical activity counselling practices, perceived exercise benefits, literature evidence, and research priorities...
March 6, 2024: Journal of Nephrology
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