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Yi-Chuan Xiao

Ben-Rui Zhao, Bao-Quan Yao, Chuan-Peng Qian, Gao-You Liu, Yi Chen, Rui-Xue Wang, Tong-Yu Dai, Xiao-Ming Duan
A high-efficiency and high-brightness Ho:YAG master-oscillator power-amplifier (MOPA) system dual-end pumped by Tm:YLF lasers was demonstrated. The maximum output power of 231 W at a wavelength of 2090.7 nm was achieved with pulse repetition frequency of 10 kHz and pulse width of 22.9 ns, corresponding to pulse energy of 23.1 mJ and peak power of ∼1  MW. The extraction efficiency of the amplifier system was more than 60%. The beam quality factor M2 was measured to be ∼1.05. Using the Ho:YAG MOPA system as the pump source, the ZnGeP2 optical parametric oscillator delivered an output power of 110 W, corresponding to slope efficiency of 62%...
December 15, 2018: Optics Letters
Jun Xiao, Jian-Hong Zhong, Sheng-Hong Wei, Zai-Sheng Ye, Fu-Sheng Gong, Chang Wang, Yi Zeng, Lu-Chuan Chen
BACKGROUND: Cancer associated fibroblasts (CAFs) are known to be crucial constituents of cancer microenvironment (CME) and play an important role in initiation, progression and metastasis of various types of cancer, such as oral cancer, pancreatic cancer, and gastric cancer. CAFs are usually derived from normal fibroblasts (NFs), but the mechanism of the transition in gastric cancer has not yet been fully elucidated. METHODS: qRT-PCR and western blot were employed to investigate differences of miR-141 and STAT4 expression respectively...
November 28, 2018: Experimental and Molecular Pathology
Gui-Yuan Xiao, Bin Peng, Ying Hu, Dou Qu, Min-Qing Lai, Yu Gong, Feng-Lan Zhao, Hong Yi, Yu Jia, Wei-Kang Zhou, Shan-Chuan Lei, Sha-Li Wang, Jing Xia, Deng-Zhi Lv, Shan Geng, Rong-Li Bai, Xiao-Ni Zhong
With the objective of investigating the characteristics influencing high-risk sexual behaviours in elderly men (60-74 years of age) in Chongqing, China, a total of 1433 healthy elderly men with sexual intercourse frequencies of one to six times/month who were willing to participate in the questionnaires were studied at four hospitals. We measured serum testosterone levels and performed follow-ups every six months, with a total of 1128 elderly men followed up after two years. We also investigated socio-economic and demographic characteristics (age, education, income, location, marital status and number of marriages), types of sexual partners, age differences with fixed sexual partners, frequency of sexual intercourse, combined basic age-related diseases, sexually transmitted infections (STIs) education, elderly self-care ability and high-risk sexual behaviours (frequency of sexual intercourse and number of sexual partners) using questionnaires...
November 28, 2018: International Journal of STD & AIDS
Tian-Ju Wan, Yi-Chuan Yu, Xiao-Gang Zhao, Ping Tang, Yong-Shu Gong
Background: Some patients still complain of residual dizziness after successful canalith repositioning procedure (CRP) for benign paroxysmal positional vertigo (BPPV). Previous study found that compared to the low-dose betahistine, the high-dose betahistine could yield better efficacy in treating residual dizziness. Therefore, this study was conducted to assess whether the addition of cognitive behavioral therapy (CBT) could make low-dose betahistine produce similar results to high-dose betahistine in treating residual dizziness...
2018: Neuropsychiatric Disease and Treatment
Z K Lin, W J Song
Wu Jinshou()[(1785-1795)-(1844-1851)]once wanted to take the imperial examination, but in late Qing Dynasty, under the depressed situation of economics and politics, he was trapped in countryside as many lower intellectuals, and chose medicine as another way to earn a living. In fact, he was both a doctor and a literatus. He kept friends with scholars, such as Zhang Tingji, Yao Wentian, Lu Changchun, Wei Guangfu, and scholar-physicians like Chen XIshu, Lu zeng and also Xu Jin's family, famous doctors at that time...
July 28, 2018: Zhonghua Yi Shi za Zhi, Chinese Journal of Medical History
Chuan-Yi Peng, Yan-Ling Zhang, Wei Song, Ya-Ning Lv, Qian Xu, Ping Zheng, Zhu-Zheng Zhang, Xiao-Chun Wan, Ru-Yan Hou, Hui-Mei Cai
BACKGROUND: Confirmation of food labeling that claims production in a small geographic region is critical to traceability, quality control and brand protection. In the current study, isotope ratio mass spectrometry (IRMS) was used to generate profiles of δ13 C and δ15 N to determine if the stable isotope signatures of Keemun black tea differ within the three counties that claim production. Other factors (cultivar type, leaf maturity and manufacturing process) were considered for their potential effects...
November 9, 2018: Journal of the Science of Food and Agriculture
Jiang-Nan Wu, Wei-Rong Gu, Xi-Rong Xiao, Yi Zhang, Xiao-Tian Li, Chuan-Min Yin
BACKGROUND/OBJECTIVES: Gestational weight gain (GWG) recommendations for pregnant women with gestational diabetes mellitus (GDM) in China are lacking. The present study aims to examine whether specific GWG targets for women with GDM can improve pregnancy outcomes in comparison with GWG according to the Institute of Medicine (IOM) targets. SUBJECTS/METHODS: Pregnant women diagnosed with GDM were selected from a retrospective cohort study of 8299 singleton pregnant women aged 18-45 years in 2012 (n = 1820)...
October 30, 2018: European Journal of Clinical Nutrition
Jun-Chi Xu, Fei Gao, Yi-An Liu, Xiao-Long Zhang, Hui Chen, Xiao-Yan Zhu, Hua-Feng Song, Feng Qian, Ming Li, Chen Yang, Chuan-Wu Zhu, Ping Xu
This study analysed the biological significance of TLT-2 on CD8+ T cells in hepatitis B patients and provided a theoretical basis for the potential role of TLT-2 as an immune regulator. Flow cytometry sorting, isobaric tags for relative and absolute quantitation and short hairpin RNAs were used to analyse the function of TLT-2 on CD8+ T cells in hepatitis B patients. The TLT-2 expression levels in the acute hepatitis B and chronic hepatitis B groups were significantly higher than that in the healthy control group and were positively correlated with ALT and AST...
October 25, 2018: Clinical and Experimental Medicine
Yi-Ning Qiu, Guo-Hui Wang, Fen Zhou, Jin-Jin Hao, Li Tian, Long-Fei Guan, Xiao-Kun Geng, Yu-Chuan Ding, He-Wen Wu, Ke-Zhong Zhang
BACKGROUND: The increasing epidemic of fine particulate matter (PM2.5) is a serious threat to human health. It induces the occurrence of liver fibrosis, but its molecular mechanism is not yet clear. The molecular mechanisms of PM2.5 inducing liver fibrosis were investigated in this study. METHODS: The cell viability of LX-2 cells and primary hepatic stellate cells (HSCs) was detected using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay...
January 15, 2019: Ecotoxicology and Environmental Safety
Yi Hou, Xuemei Cao, Xiangnan Hu, Xinyu Li, Xiaoqin Shi, Hongying Wang, Chuan Peng, Jiayu Li, Jibin Li, Qifu Li, Chaodong Wu, Xiaoqiu Xiao
Traditional thiazolidinediones (TZDs), such as rosiglitazone, are peroxisome proliferator-activated receptor γ (PPARγ) potent agonists that can be used to treat type 2 diabetes but carry unwanted effects, including increased risk for fracture. The present work aimed to compare the insulin-sensitizing efficacies and bone-loss side effects of CMHX008, a novel TZDs-like PPARγ partial agonist, with those of rosiglitazone. A TR-FRET PPARγ competitive binding assay was used to compare the binding affinity between CMHX008 and rosiglitazone...
September 2018: Genes & Diseases
Jian Zhou, Hui-Chuan Sun, Zheng Wang, Wen-Ming Cong, Jian-Hua Wang, Meng-Su Zeng, Jia-Mei Yang, Ping Bie, Lian-Xin Liu, Tian-Fu Wen, Guo-Hong Han, Mao-Qiang Wang, Rui-Bao Liu, Li-Gong Lu, Zheng-Gang Ren, Min-Shan Chen, Zhao-Chong Zeng, Ping Liang, Chang-Hong Liang, Min Chen, Fu-Hua Yan, Wen-Ping Wang, Yuan Ji, Wen-Wu Cheng, Chao-Liu Dai, Wei-Dong Jia, Ya-Ming Li, Ye-Xiong Li, Jun Liang, Tian-Shu Liu, Guo-Yue Lv, Yi-Lei Mao, Wei-Xin Ren, Hong-Cheng Shi, Wen-Tao Wang, Xiao-Ying Wang, Bao-Cai Xing, Jian-Ming Xu, Jian-Yong Yang, Ye-Fa Yang, Sheng-Long Ye, Zheng-Yu Yin, Bo-Heng Zhang, Shui-Jun Zhang, Wei-Ping Zhou, Ji-Ye Zhu, Rong Liu, Ying-Hong Shi, Yong-Sheng Xiao, Zhi Dai, Gao-Jun Teng, Jian-Qiang Cai, Wei-Lin Wang, Jia-Hong Dong, Qiang Li, Feng Shen, Shu-Kui Qin, Jia Fan
Background: Hepatocellular carcinoma (HCC) (about 85-90% of primary liver cancer) is particularly prevalent in China because of the high prevalence of chronic hepatitis B infection. HCC is the fourth most common malignancy and the third leading cause of tumor-related deaths in China. It poses a significant threat to the life and health of Chinese people. Summary: This guideline presents official recommendations of the National Health and Family Planning Commission of the People's Republic of China on the surveillance, diagnosis, staging, and treatment of HCC occurring in China...
September 2018: Liver Cancer
Guo-Yi Su, Chuan-Bing Wang, Hao Hu, Jun Liu, Hong-Yuan Ding, Xiao-Quan Xu, Fei-Yun Wu
OBJECTIVES: To evaluate the effect of laterality, gender, age and body mass index (BMI) on fat fraction (FF) measurements of both parotid glands (PGs) and submandibular glands (SMGs) by using: Iterative decomposition of water and fat with echo asymmetry and least-squares estimation method (IDEAL-IQ). METHODS: A total of 87 healthy participants were enrolled in our study. IDEAL-IQ image was scanned using a 3.0 T scanner. Paired t test was performed to compare the difference on FF of both PGs and SMGs between left and right side...
October 26, 2018: Dento Maxillo Facial Radiology
Yi-Pin Lv, Liu-Sheng Peng, Qi-Hong Wang, Na Chen, Yong-Sheng Teng, Ting-Ting Wang, Fang-Yuan Mao, Jin-Yu Zhang, Ping Cheng, Yu-Gang Liu, Hui Kong, Xiao-Long Wu, Chuan-Jie Hao, Weisan Chen, Jiang Zhu, Bin Han, Qiang Ma, Ke Li, Quanming Zou, Yuan Zhuang
Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, their precise mechanism of communication in gastric cancer remains largely unclear. Here, we found that patients with GC showed a significantly higher mast cell infiltration in tumors. Mast cell levels increased with tumor progression and independently predicted reduced overall survival. Tumor-derived adrenomedullin (ADM) induced mast cell degranulation via PI3K-AKT signaling pathway, which effectively promoted the proliferation and inhibited the apoptosis of GC cells in vitro and contributed to the growth and progression of GC tumors in vivo, and the effect could be reversed by blocking interleukin (IL)-17A production from these mast cells...
October 10, 2018: Cell Death & Disease
Zheng Li, Zhen-Wei Zhang, Shao-Xiao Yu, Jia-Chuan Zhuang, Yu-Hai Ke, Yi Xiong, Hui-Xin Lin, Wen-Feng Chen
Background: Arterialized vein flap is a kind of unphysiological flap. Unphysiological reconstruction of blood circulation leads to higher load than that supported by physiological flap and is the culprit of flap swelling, blood stasis, skin blistering, and necrosis after flap grafting. To resolve the multiple disadvantages of traditional flap grafting, by introducing the principles of fluid mechanics, shunt-decompression surgery is prepared to decline the circulation preload and improve the prognosis of arterialized vein flap grafting...
2018: Cancer Cell International
Wei Fan, Xiu Kui Gao, Xi Sheng Rao, Yin Pu Shi, Xiao Ceng Liu, Fei Ya Wang, Yu Fen Liu, Xiao Xia Cong, Min Yi He, Shui Bo Xu, Wei Liang Shen, Yue Shen, Shi Gui Yan, Yan Luo, Boon Chuan Low, Hongwei Ouyang, Zhang Bao, Li Ling Zheng, Yi Ting Zhou
The regenerative process of injured muscle is dependent on the fusion and differentiation of myoblast cells derived from muscle stem cells. Hsp70 is important for maintaining skeletal muscle homeostasis and regeneration but the precise cellular mechanism remains elusive. Here we found that Hsp70 was upregulated during myoblast differentiation. Depletion or inhibition of Hsp70/Hsc70 impaired myoblast differentiation. Importantly, overexpression of p38MAPKα, but not AKT1, rescued the impairment of myogenic differentiation in Hsp70- or Hsc70-depleted myoblasts...
October 1, 2018: Molecular and Cellular Biology
Jin-Peng Wang, Ji-Gao Yu, Jing Li, Peng-Chuan Sun, Li Wang, Jia-Qing Yuan, Fan-Bo Meng, Sang-Rong Sun, Yu-Xian Li, Tian-Yu Lei, Yu-Xin Pan, Wei-Na Ge, Zhen-Yi Wang, Lan Zhang, Xiao-Ming Song, Chao Liu, Xue-Qian Duan, Shao-Qi Shen, Yang-Qin Xie, Yue Hou, Jin Zhang, Jian-Yu Wang, Xiyin Wang
The genome of kiwifruit (Actinidia chinensis) was sequenced previously, the first in the Actinidiaceae family. It was shown to have been affected by polyploidization events, the nature of which has been elusive. Here, we performed a reanalysis of the genome and found clear evidence of 2 tetraploidization events, with one occurring ∼50-57 million years ago (Mya) and the other ∼18-20 Mya. Two subgenomes produced by each event have been under balanced fractionation. Moreover, genes were revealed to express in a balanced way between duplicated copies of chromosomes...
September 28, 2018: iScience
Xin-Xin Shen, Fang-Zhou Qiu, Gui-Xia Li, Meng-Chuan Zhao, Ji Wang, Chen Chen, Li Zhao, Ju-Ju Qi, Hong Liu, Yi Zhang, Xiao-Zhou He, Le Wang, Zhi-Shan Feng, Xue-Jun Ma
Some serotypes of enterovirus (EV) may lead to transient and symptomatic gastrointestinal infections while others are commensal residents of the human gut. To determine whether certain EV types are more often associated with diarrhea, we conducted a preliminary study on the prevalence of EV serotypes and common diarrhea viruses in fecal samples of diarrhea children and healthy controls. EV was tested with one step nest polymerase chain reaction and typed by direct sequencing while common causative diarrhea viruses rotavirus (RV), norovirus (NoV), adenovirus (AdV), bocavirus (HBoV), and astrovirus (AstV) were screened with multiplex PCR assays...
September 25, 2018: Archives of Virology
Zhi-Qin Liang, Tao-Tao Zhuang, Ali Seifitokaldani, Jun Li, Chun-Wei Huang, Chih-Shan Tan, Yi Li, Phil De Luna, Cao Thang Dinh, Yongfeng Hu, Qunfeng Xiao, Pei-Lun Hsieh, Yuhang Wang, Fengwang Li, Rafael Quintero-Bermudez, Yansong Zhou, Peining Chen, Yuanjie Pang, Shen-Chuan Lo, Lih-Juann Chen, Hairen Tan, Zheng Xu, Suling Zhao, David Sinton, Edward H Sargent
Copper-based materials are promising electrocatalysts for CO2 reduction. Prior studies show that the mixture of copper (I) and copper (0) at the catalyst surface enhances multi-carbon products from CO2 reduction; however, the stable presence of copper (I) remains the subject of debate. Here we report a copper on copper (I) composite that stabilizes copper (I) during CO2 reduction through the use of copper nitride as an underlying copper (I) species. We synthesize a copper-on-nitride catalyst that exhibits a Faradaic efficiency of 64 ± 2% for C2+ products...
September 20, 2018: Nature Communications
Wei-Ji Weng, Chun Yang, Xian-Jian Huang, Yong-Ming Zhang, Jin-Fang Liu, Jie-Min Yao, Zi-Heng Zhang, Xue-Song Wu, Tao Mei, Chuan-Dong Zhang, Jun Jia, Xiao-Feng Shi, Qing Mao, Jun-Feng Feng, Guo-Yi Gao, Ji-Yao Jiang
A prospective observational study collected temperature data from 51 patients in 11 neurosurgical centers and follow-up outcome information at 6 months in 49 patients. Brain temperature (Tbr ) was measured directly by an intraventricular temperature sensor. Axillary temperature (Tax ) and rectal temperature (Tre ) were measured by electric thermometers. Tbr was 0.4 to 1.5°C higher than body temperature. Tre correlated well with the Tbr (coefficient: 0.7378; p < 0.05). Among all patients, Glasgow Coma Scale (GCS) scores on admission were significantly lower in the patients with post-operatively extreme peak temperature (Tpeak , < 37°C or >39°C in first 24 h) and major temperature variation (Tvari > 1°C in first 12 h; p < 0...
October 10, 2018: Journal of Neurotrauma
Tian-Shu Yang, Zong-Quan Zhou, Yi-Lin Hua, Xiao Liu, Zong-Feng Li, Pei-Yun Li, Yu Ma, Chao Liu, Peng-Jun Liang, Xue Li, Yi-Xin Xiao, Jun Hu, Chuan-Feng Li, Guang-Can Guo
The faithful storage and coherent manipulation of quantum states with matter-systems would enable the realization of large-scale quantum networks based on quantum repeaters. To achieve useful communication rates, highly multimode quantum memories are required to construct a multiplexed quantum repeater. Here, we present a demonstration of on-demand storage of orbital-angular-momentum states with weak coherent pulses at the single-photon-level in a rare-earth-ion-doped crystal. Through the combination of this spatial degree-of-freedom (DOF) with temporal and spectral degrees of freedom, we create a multiple-DOF memory with high multimode capacity...
August 24, 2018: Nature Communications
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