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Zheng-gang Liu

Chi Li, Wen-Ya Feng, Ai-Wei Lin, Guo Zheng, Yan-Chun Wang, Yan-Jun Han, Jian-Min Zhong, Jing Bi, Qiong Luo, Fang-Chao Zhao, Ping Jin, Ling-Yun Guo, Na Li, Jie Yu, Xiao-Tao Yang, Jun Liang, Ji-Kui Deng, Yong-Jun Li, Yu-Jiao Wang, Xiong-Ying Yu, Dong-Meng Wang, Liang Ru, Juan Chen, Yong-Hong Yang, Qiao-Zhi Yang, Gang Liu
OBJECTIVE: To explore the clinical characteristics and etiology of bacterial meningitis (BM) in Chinese children. METHOD: BM cases in children 28days to 18 years old were collected from January 2014-December 2016 and screened according to World Health Organization standards. Clinical features, pathogens, and resistance patterns were analyzed. RESULTS: Overall, 837 cases were classified into five age groups: 28 days-2 months (17.0%), 3-11 months (27...
July 6, 2018: International Journal of Infectious Diseases: IJID
Xian-Kai Wei, Yi Xiong, Xiao-Ning Li, Min Zheng, Yan Pan, Xiao-Xia He, Jing-Jing Liang, Cheng Liu, Yi-Zhi Zhong, Lian-Bin Zou, Lie-Feng Zheng, Jian-Gang Guo, Chang-Ting Li, Sheng-Bin Huang, Jia-Zhong Gan, Zhen-Mu Meng, Jian Yang, Hai-Bo Tang, Qi Liu, Ting Rong Luo
BACKGROUND: Guangxi is the province most seriously affected by rabies virus (RABV) in China. Those most affected by RABV each year are people in rural areas, where dogs are the main cause of human infection with the virus. METHODS: In this study, we established a rabies vaccination demonstration program that included eradication, core, and peripheral areas. This program was implemented for 9 years and comprised three stages: 12 counties in the first stage (2008-2010), 21 counties in the second stage (2011-2013), and then extending to all counties of Guangxi Province in the third stage (2014-2016)...
August 10, 2018: BMC Infectious Diseases
Xiaolong Hu, Gang Liu, Yimeng Li, Yuting Wei, Shaobi Lin, Shuqiang Liu, Yunlin Zheng, Defu Hu
The gut microbiota plays a key role in the nutritional ecology of ruminants, and host diet has a significant effect on these microbial communities. Longitudinal studies assessing variation of seasonal microbiota in animals can provide a comparative context for interpreting the adaptive significance of such changes. However, few studies have investigated the effects of seasonally-related dietary shifts on the gut microbial communities of endangered forest musk deer (FMD), and the national breeding programs need this information to promote the growth of captive populations...
2018: Frontiers in Microbiology
Shiwei Guo, Suizhi Gao, Rendong Liu, Jing Shen, Xiaohan Shi, Sijia Bai, Huan Wang, Kailian Zheng, Zhuo Shao, Chuanyu Liang, Siying Peng, Gang Jin
A patient-derived xenograft (PDX) approach, which relies on direct transplantation of tumor specimens into an immunocompromised animal, is a commonly used method for investigating tumor therapy predictions in vivo. This study evaluated influencing factors, including clinical, oncological, and genetic variables, for a pancreatic PDX model in mice. Tumor specimens were obtained from 121 patients with pancreatic ductal adenocarcinoma who underwent surgical resection at the Changhai Pancreatic Surgery Medical Center (Shanghai, China) between April 2016 and February 2017...
August 9, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Zhi-Xia Yue, Rui-Qi Gao, Chao Gao, Shu-Guang Liu, Xiao-Xi Zhao, Tian-Yu Xing, Jing Niu, Zhi-Gang Li, Hu-Yong Zheng, Wei Ding
Background: Cajal body (CB) is a nucleic organelle where small nuclear ribonucleoproteins undergo modification, maturation, splicing and/or assembly. Coilin is the marker structural protein of CBs. The expression level and cellular localization of coilin is sensitive to chemotherapeutic reagents, such as cisplatin. The gene of cyclin-dependent kinase inhibitor 1B (p27) is located with a high incidence translocation region of leukemic chromosomes, and its expression was of prognosis values in a variety of adult leukemia types...
2018: Cancer Cell International
Jiao-Sheng Zhang, Gang Liu, Wen-Shuang Zhang, Hai-Yan Shi, Gen Lu, Chang-An Zhao, Chang-Chong Li, Yan-Qi Li, Ya-Nan Shao, Dai-Yin Tian, Ming-Jie Ding, Chun-Yan Li, Li-Juan Luo, Xiao-Yan Dong, Ping Jin, Ping Wang, Chun-Mei Zhu, Chuan-Qing Wang, Yue-Jie Zheng, Ji-Kui Deng, Mike Sharland, Ying-Fen Hsia, Kun-Ling Shen, Yong-Hong Yang
BACKGROUND: Children as a population have high antimicrobial prescribing rates which may lead to high resistance of bacteria according to data from some single-center surveys of antibiotic prescribing rates in China. The acquirement of baseline data of antibiotic prescribing is the basis of developing intervention strategies on inappropriate antimicrobial prescriptions. Few studies show clearly the pattern and detailed information on classes of antibiotics and distribution of indications of antibiotic prescriptions in children in China...
July 30, 2018: World Journal of Pediatrics: WJP
Ziyi Liu, Le Wang, Gang Hua, Qilin Zhang, Zhenxing Niu, Ying Wu, Nanning Zheng
It is a challenging task to extract segmentation mask of a target from a single noisy video, which involves object discovery coupled with segmentation. To solve this challenge, we present a method to jointly discover and segment an object from a noisy video, where the target disappears intermittently throughout the video. Previous methods either only fulfill video object discovery, or video object segmentation presuming the existence of the object in each frame. We argue that jointly conducting the two tasks in a unified way will be beneficial...
July 30, 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
Xiaohui Ma, Yaru Liu, Weiming Song, Zheng Wang, Xiangyu Liu, Gang Xie, Sanping Chen, Shengli Gao
A novel one-dimensional azido-cobalt(ii) compound, [Co2(1-mbt)2(N3)4]n (1) (1-mbt = 1-((2-propyl-imidazol-1-yl)methyl)-benzo[1,2,3]triazole), was solvothermally synthesized. X-ray crystal structure analysis demonstrates that two crystallographically independent Co(ii) atoms in the asymmetrical unit of compound 1 exhibit a rectangular pyramid geometry. The 3D supermolecular network of 1 consists of well-isolated 1D metal chains in which the azido bridging ligands assume an unusual pattern of combination with the Co(ii) centre as the sign of [-EE-EO-EO-EO-]n...
July 30, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
Yu-Qing Liu, Zhi-Ji Chen, Gang Li, Dan Lai, Peng Liu, Yun Zheng
The aim of this study was to evaluate the early and sustained effects of tinnitus educational counseling on chronic primary tinnitus and related problems. A descriptive longitudinal cohort study was conducted with 159 adult patients suffering from chronic primary tinnitus and sleep problems. All patients received tinnitus educational counseling, sleep adjustment, and vegan dietary advice. At short-term assessment within 3 months and long-term follow-up at 6-26 months, perceived changes in tinnitus were assessed with the Tinnitus Handicap Inventory (THI) and the Tinnitus Evaluation Questionnaire (TEQ), respectively...
2018: BioMed Research International
Hu Hong-Qiang, Shu Mang-Qiao, Xue Fen, Liu Shan-Shan, Cao Hui-Juan, Hou Wu-Gang, Yan Wen-Jun, Peng Zheng-Wu
Hyperbaric oxygen (HBO) preconditioning (PC) has been suggested as a feasible method to provide neuroprotection from postoperative cognitive dysfunction (POCD). However, whether HBO-PC can ameliorate cognitive deficits induced by isoflurane, and the possible mechanism by which it may exert its effect, has not yet been clarified. In the present study, middle-aged mice were exposed to isoflurane anesthesia (1.5 minimal alveolar concentration [MAC]) for 2 h to establish a POCD model. After HBO preconditioning, cognitive function and expression of hippocampal sirtuin 1 (Sirt1), nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase 1 (HO-1) were evaluated 24 h following isoflurane treatment, in the presence or absence of Sirt1 knockdown by short hairpin RNA (shRNA)...
July 21, 2018: Physiology & Behavior
Yun Lu, Qiyue Yu, Yuanxiang Gao, Yunpeng Zhou, Guangwei Liu, Qian Dong, Jinlong Ma, Lei Ding, Hongwei Yao, Zhongtao Zhang, Gang Xiao, Qi An, Guiying Wang, Jinchuan Xi, Weitang Yuan, Yugui Lian, Dianliang Zhang, Chunbo Zhao, Qin Yao, Wei Liu, Xiaoming Zhou, Shuhao Liu, Qingyao Wu, Wenjian Xu, Jianli Zhang, Dongshen Wang, Zhenqing Sun, Yuan Gao, Xianxiang Zhang, Jilin Hu, Maoshen Zhang, Guanrong Wang, Xuefeng Zheng, Lei Wang, Jie Zhao, Shujian Yang
Magnetic resonance imaging (MRI) is the gold standard for confirming a pelvic lymph node metastasis diagnosis. Traditionally, medical radiologists have analyzed MRI image features of regional lymph nodes to make diagnostic decisions based on their subjective experience; this diagnosis lacks objectivity and accuracy. This study trained a faster region-based convolutional neural network (Faster R-CNN) with 28,080 MRI images of lymph node metastasis, allowing the Faster R-CNN to read those images and to make diagnoses...
July 19, 2018: Cancer Research
Zi-Yi Jin, Gina Wallar, Jin-Yi Zhou, Jie Yang, Ren-Qiang Han, Pei-Hua Wang, Ai-Min Liu, Xiao-Ping Gu, Xiao-Feng Zhang, Xu-Shan Wang, Ming Su, Xu Hu, Zheng Sun, Gang Li, Li-Na Mu, Qing-Yi Lu, Xing Liu, Li-Ming Li, Na He, Ming Wu, Jin-Kou Zhao, Zuo-Feng Zhang
Garlic consumption has been associated inversely with esophageal cancer (EC); however, its interactions with tobacco smoking and alcohol consumption have never been evaluated in an epidemiological study. We evaluated the potential interactions between garlic intake and tobacco smoking as well as alcohol consumption in a population-based case-control study with 2969 incident EC cases and 8019 healthy controls. Epidemiologic data were collected by face-to-face interviews using a questionnaire. The adjusted odds ratio (OR) and 95% confidence interval (CI) were estimated and additive and multiplicative interactions were evaluated using unconditional logistic regression models, adjusting for potential confounding factors...
July 11, 2018: European Journal of Cancer Prevention
Zhi-Ling Li, Yi-Xi Liu, Zheng Jiao, Gang Qiu, Jian-Quan Huang, Yu-Bo Xiao, Shu-Jin Wu, Chen-Yu Wang, Wen-Juan Hu, Hua-Jun Sun
The main goal of our study was to characterize the population pharmacokinetics of vancomycin in critically ill Chinese neonates to develop a pharmacokinetic model and investigate factors that have significant influences on the pharmacokinetics of vancomycin in this population. The study population consisted of 80 neonates in the neonatal intensive care unit (ICU) from which 165 trough and peak concentrations of vancomycin were obtained. Nonlinear mixed effect modeling was used to develop a population pharmacokinetic model for vancomycin...
2018: Frontiers in Pharmacology
Xun-Chang John Zhang, Gang Liu, Fenli Zheng
Tracking sediment source and movement is essential to fully understanding soil erosion processes. The objectives of this study were to identify dominant erosion process and to characterize the effects of upslope interrill erosion on downslope interrill and rill erosion in a preformed interrill-rill system. A coarse textured soil with 2% clay and 20% silt was packed into a physical model of a scaled small watershed, which was divided into eight topographic units and was tagged with eight rare earth element (REE) oxides...
June 1, 2018: Science of the Total Environment
Jun Yan, Xiaoling Zheng, Zhangyuanzhu Liu, Wenju Liu, Dajia Lin, Dexin Chen, Kai Li, Wei Jiang, Zhiming Li, Ning Zuo, Gang Chen, Jianping Lu, Jianxin Chen, Guoxin Li, Chris Xu, Shuangmu Zhuo
BACKGROUND:  Confocal laser endomicroscopy (CLE) requires fluorescence agents, the use of which leads to blurred images and low diagnostic accuracy owing to fluorescein leakage. We aimed to explore whether multiphoton imaging (MPI) could serve as a better method of optical biopsy. METHODS:  First, a pilot study was performed to set up the optical diagnostic criteria of MPI for benign or malignant colorectal lesions in 30 patients. Then, a blinded study was conducted to compare the sensitivity, specificity, and accuracy of MPI versus CLE imaging in 79 patients...
July 11, 2018: Endoscopy
Zheng Guan, Xin Shen, Yong-Jian Zhang, Xiao-Gang Li, Yan-Feng Gao, Jing Tan, Hui Yuan, Jing-Jie Liu
Since there were a few articles to report the treatment of severe pulmonary vasoconstriction induced by protamine in cardiac surgery, we described the use of epoprostenol to reverse this condition.A total of 5 cases of severe pulmonary vasoconstriction induced by protamine in cardiac surgery were reviewed. The demographic, clinical data and treatment process were obtained. All the patients were followed up.Severe pulmonary vasoconstriction was occurred 4 to 10 minutes after protamine infusion. The primary sign was sudden hypotension, the pulmonary artery pressure was increased gradually, the arterial oxygen partial pressure was decreased in all the patients...
July 2018: Medicine (Baltimore)
Yuanli Zhou, Xuanguo Zhang, Chao Li, Xin Yuan, Lihua Han, Zheng Li, Xiaobin Tan, Jie Song, Gang Wang, Xiaobin Jia, Liang Feng, Xiting Qiao, Jiping Liu
Fraxini Cortex (also known as Qinpi, QP) has been used for the treatment of hyperuricemia with a significant difference on efficacy of QP from different regions. However, it`s still unknown whether proportion of components is the key and why same kind of herbs have different therapeutic effects. In this study, different sources of QP were collected from Shaanxi Qinpi extracts (SQPE), Henan Qinpi extracts (HQPE), Hebei Qinpi extracts (GQPE) provinces in China. Rat model of hyperuricemia with hypoxanthine combined with potassium oxonate were established to determine the levels of blood urea nitrogen (BUN), serum uric acid (SUA), urine uric acid (UUA) and creatinine (Cr)...
July 2, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Juan Wang, Jin-Xing Liu, Chun-Hou Zheng, Ya-Xuan Wang, Xiong-Zhen Kong, Chang-Gang Weng
Tumor samples clustering based on biomolecular data is a hot issue of cancer classifications discovery. How to extract the valuable information from high dimensional genomic data is becoming an urgent problem in tumor samples clustering. In this paper, we introduce manifold regularization into low-rank representation model and present a novel method named Mixed-norm Laplacian regularized Low-Rank Representation (MLLRR) to identify the differentially expressed genes for tumor clustering based on gene expression data...
November 3, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
Yu Chen, Weifeng Tang, Chao Liu, Jing Lin, Yafeng Wang, Sheng Zhang, Gang Chen, Xiongwei Zheng
Purpose: The miRNA-146a rs2910164 C>G polymorphism may contribute to the development of cancer. However, the association between this polymorphism and the risk of esophagogastric junction adenocarcinoma (EGJA) remains unclear. In the present study, we carried out a case-control study to explore the potential relationship between miRNA-146a rs2910164 C>G polymorphism and EGJA risk. Patients and methods: In total, 1,063 EGJA patients and 1,677 cancer-free controls were enrolled...
2018: Cancer Management and Research
Ke Zheng, Jin-Xiang Tan, Fan Li, Hong-Yuan Li, Xiao-Hua Zeng, Bin-Lin Ma, Jiang-Hua Ou, Hui Li, Sui-Sheng Yang, Ai-Mei Jiang, Qing Ni, Jian-Lun Liu, Jin-Ping Liu, Hong Zheng, Yue-Yang, Rui Ling, Jian-Jun He, Zhi-Gang Li, Jian Zeng, Tian-Ning Zou, Jun Jiang, Zhang-Jun Song, Qi-Lun Liu, Guo-Sheng Ren
BACKGROUND AND PURPOSE: Breast cancer is now recognized as a clinically heterogeneous disease with a wide spectrum of epidemiological and clinicopathologic features. We aimed to evaluate whether epidemiological and clinicopathologic features are associated with the histological tumor grade of breast carcinomas in Western China. METHODS: We retrospectively collected data from the Western China Clinical Cooperation Group and assessed associations between clinicopathologic factors and histological tumor grade in 8619 female breast cancer patients...
August 2018: Translational Oncology
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