Alexander H Choi, Melanie Delgado, Kong Y Chen, Stephanie T Chung, Amber Courville, Sara A Turner, Shanna Yang, Kayla Airaghi, Irene Dustin, Patrick McGurrin, Tianxia Wu, Mark Hallett, Debra J Ehrlich
BACKGROUND: A ketogenic diet (KD) may benefit people with neurodegenerative disorders marked by mitochondrial depolarization/insufficiency, including Parkinson's disease (PD). OBJECTIVE: Evaluate whether a KD supplemented by medium chain triglyceride (MCT-KD) oil is feasible and acceptable for PD patients. Furthermore, we explored the effects of MCT-KD on blood ketone levels, metabolic parameters, levodopa absorption, mobility, nonmotor symptoms, simple motor and cognitive tests, autonomic function, and resting-state electroencephalography (rsEEG)...
April 1, 2024: BMC Neurology