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https://www.readbyqxmd.com/read/30551447/nano-hydroxy-apatite-chitosan-gelatin-scaffolds-enriched-by-a-combination-of-platelet-rich-plasma-and-fibrin-glue-enhance-proliferation-and-differentiation-of-seeded-human-dental-pulp-stem-cells
#1
Ali Sadeghinia, Soodabeh Davaran, Roya Salehi, Zahra Jamalpoor
The purpose of this study was to investigate the effects of Fibrin Glue (FG) and activated platelet-rich plasma (a-PRP) on the proliferation and osteogenic differentiation of human dental pulp stem cells (h-DPSCs). Therefore, we planned to investigate in vitro behavior of porous composite scaffolds based on chitosan-gelatin/nanohydroxyapatite (CS-G/nHA) treated with FG and a-PRP. The porous structure of CS-G/nHA was prepared using combination of particle leaching and freeze-drying methods. The a-PRP was prepared from the centrifugation of whole blood activated with calcium chloride...
January 2019: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/30544388/radiculoplasty-with-reconstruction-using-3d-printed-artificial-dura-mater-for-the-treatment-of-symptomatic-sacral-canal-cysts-two-case-reports
#2
Bin Liu, Zhenyu Wang, Guozhong Lin, Jia Zhang
RATIONALE: Currently, interventional injection of albumin glue and nerve sleeve plasty by cyst excision is the main treatment for sacral cysts. However, albumin glue can only be used in patients with partial cystic neck stenosis, and surgical treatment may result in postoperative complications such as numbness and cyst recurrence. Here, a modified radiculoplasty is presented, in which the lamina is restored with the nerve root wrapped with 3-dimensional (3D)-printed artificial dura mater...
December 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30543731/transplantation-of-bone-marrow-derived-mesenchymal-stem-cells-platelet-rich-plasma-and-fibrin-glue-for-periodontal-regeneration
#3
Mahdieh Rezaei, Shahram Jamshidi, Anna Saffarpour, Mahdi Ashouri, Reza Rahbarghazi, Amir Reza Rokn, Pouriya Motahari
Appropriate regeneration of periodontal tissues is the primary purpose of periodontal disease treatment. The present study assessed the impact of three key regenerative elements-platelet-rich plasma (PRP), canine bone marrow mesenchymal stem cells (cBM-MSCs), and fibrin glue-on periodontal regeneration. In each of the study's five dogs, Class II furcation defects were established on the buccal surface of five teeth. One tooth (five total) from each dog was placed into one of five groups: (1) PRP + fibrin glue, (2) PRP + fibrin glue + cBM-MSCs, (3) fibrin glue, (4) cBM-MSCs + fibrin glue, and (5) control (no treatment)...
January 2019: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/30523143/osseous-versus-nonosseous-spinal-epidural-arteriovenous-fistulas-experiences-of-13-patients
#4
Y Song, S H Cho, D W Lee, J J Sheen, J H Shin, D C Suh
BACKGROUND AND PURPOSE: Spinal epidural arteriovenous fistulas are rare vascular malformations. We present 13 patients with spinal epidural arteriovenous fistulas, noting the various presenting symptom patterns, imaging findings related to bone involvement, and outcomes. MATERIALS AND METHODS: Among 111 patients with spinal vascular malformations in the institutional data base from 1993 to 2017, thirteen patients (11.7%) had spinal epidural arteriovenous fistulas...
December 6, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/30480634/a-step-by-step-procedure-for-bone-regeneration-using-calcium-phosphate-scaffolds-from-site-preparation-to-graft-placement
#5
Antonello Maria Messina, Luca Marini, Daniel S Oh, Ettore Marini
Hydroxyapatite (HA) is the main mineral component of bone and teeth. HA is often used as a bone substitute and especially in its granular form it is osteoconductive and osseointegrating as shown by many investigations in animals and humans. HA granules are used for filling bone defects, but they have poor handling qualities and retention at the surgical site, leading to graft voids between the granules and bone tissue and resulting in mechanical instability. Furthermore HA implantation is not constantly followed by favorable results, especially when it is carried out for augmentation of the alveolar ridge...
November 22, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/30428307/modular-core-shell-polymeric-nanoparticles-mimicking-viral-structures-for-vaccination
#6
Bo Lou, Ans De Beuckelaer, Eger Boonstra, Dandan Li, Bruno G De Geest, Stefaan De Koker, Enrico Mastrobattista, Wim E Hennink
Recent advances in the development of protein-based vaccines have expanded the opportunities for preventing and treating both infectious diseases as well as cancer. However, the development of readily and efficient antigen delivery systems capable of stimulating strong cytotoxic T-lymphocyte (CTL) responses remains a challenge. With the attempt to closely mimic the properties of viruses in terms of their size and molecular organization, we constructed RNA (which is a ligand for Toll-like receptor 7 (TLR7) and TLR8) and antigen-loaded nanoparticles resembling the structural organization of viruses...
November 11, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/30418400/use-of-cyanoacrylate-glue-for-replacing-orbital-bone-after-lateral-orbitotomy-a-pilot-study
#7
Md Shahid Alam
No abstract text is available yet for this article.
November 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/30412179/-a-variant-of-the-modification-of-the-rhinosurgical-intervention-with-the-use-of-the-hemostatic-glue
#8
A D Morozov
The objective of the present study was to evaluate the dynamics of the nasal breathing function and the quality of life in the patients following septoplastic surgery with the use of the classical method in comparison with the application of the latex tissue glue. The study included 58 patients presenting with diagnosis of deflected septum of the nose and vasomotor rhinitis. The following methods were employed for the purpose: anterior active rhinomanometry, evaluation of the transport function of the nasal cavity, and the questionnaire study for the determination of the patients' quality of life...
2018: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/30411215/a-new-affordable-and-easy-to-make-pelvic-model-for-training-in-complex-urogynecological-laparoscopic-procedures
#9
Tamara Serdinšek, Branka Žegura Andrić, Igor But
INTRODUCTION AND HYPOTHESIS: Our aim was to introduce a new affordable and easy-to-make pelvic model for training in complex urogynecological laparoscopic procedures. METHODS: We modified a commercial female pelvic model consisting of sacrum, coccyx, two hip bones, the pubic symphysis, the fifth lumbar vertebra with intervertebral disc, and certain pelvic ligaments. We used sponge foam paper, felt fabric pieces, chenille stems, foam, plastic ties, fabric glue, and a thick, coated wire to create pelvic floor, uterus/vaginal cuff, bladder, both ureters, and anterior longitudinal and pectineal ligaments...
November 8, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/30374697/establishment-of-widely-applicable-dna-extraction-methods-to-identify-the-origins-of-crude-drugs-derived-from-animals-using-molecular-techniques
#10
Hiroaki Nakanishi, Katsumi Yoneyama, Yoshie Hayashizaki, Masaaki Hara, Aya Takada, Kazuyuki Saito
We established widely applicable DNA extraction methods to identify the origins of crude drugs derived from animals. Twenty-one samples including 17 kinds of crude drug derived from animals were examined. DNA was extracted from most of the crude drugs by adjustment of the QIAamp® DNA Mini Kit. DNA extraction was performed successfully using phenol to remove impurities after applying a proteinase treatment. DNA extraction was performed successfully by decalcification treatment using ethylenediaminetetraacetic acid (EDTA), before applying the proteinase treatment for crude drugs having high calcium content, such as those from oyster shell and cuttlefish bone...
October 29, 2018: Journal of Natural Medicines
https://www.readbyqxmd.com/read/30340603/the-potent-anti-inflammatory-effect-of-guilu-erxian-glue-extracts-remedy-joint-pain-and-ameliorate-the-progression-of-osteoarthritis-in-mice
#11
Yen-Jung Chou, Jiunn-Jye Chuu, Yi-Jen Peng, Yu-Hsuan Cheng, Chin-Hsien Chang, Chieh-Min Chang, Hsia-Wei Liu
BACKGROUND: Osteoarthritis (OA) is a slow progressing, degenerative disorder of the synovial joints. Guilu Erxian Glue (GEG) is a multi-component Chinese herbal remedy with long-lasting favorable effects on several conditions, including articular pain and muscle strength in elderly men with knee osteoarthritis. The present study aimed to identify the effects of Guilu Erxian Paste (GE-P) and Liquid (GE-L) extracted from Guilu Erxian Glue in anterior cruciate ligament transection (ACLT)-induced osteoarthritis mice, and to compare the effectiveness of different preparations on knee cartilage degeneration during the progression of osteoarthritis...
October 19, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/30321966/a-prospective-evaluation-of-bone-marrow-aspirate-concentrate-and-microfracture-in-the-treatment-of-osteochondral-lesions-of-the-talus
#12
Evelyn P Murphy, Niall P McGoldrick, Mark Curtin, Stephen R Kearns
BACKGROUND: The term osteochondral lesion (OCL) refers to a defect involving the chondral surface and or subchondral bone. These lesions are associated with ankle injuries with bony and soft tissue and cause pain, decreased range of motion, swelling and impact adversely on quality of life. To date the standard treatment has been isolated microfracture (BMS). The aim of this study was to compare the outcomes of BMS alone to BMS augmented with bone marrow aspirate concentrate (BMAC) in the treatment of ankle OCLs...
February 22, 2018: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/30283715/one-burr-hole-craniotomy-modified-presigmoid-approach-in-helsinki-neurosurgery
#13
Joham Choque-Velasquez, Juha Hernesniemi
Background: In this video abstract, we present a one burr-hole craniotomy for a modified presigmoid approach developed in Helsinki Neurosurgery to access the space extended to both middle and posterior fossa. Thus, indications for this approach are lesions that extend to both middle and posterior fossa, petroclival tumors, basilar tip aneurysms located extremely low below the posterior clinoid process, trunk basilar aneurysms, and bypass procedures from the P2 segment of the posterior cerebral artery...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/30282426/use-of-resorbable-mesh-and-fibrin-glue-for-restoration-in-comminuted-fracture-of-anterior-maxillary-wall
#14
Jae-Hyuk Yang, Suk Choo Chang, Jin Yong Shin, Si-Gyun Roh, Nae-Ho Lee
BACKGROUND: The facial bone has a complex structure compared to other bones, and various types of fractures can occur due to its characteristics. Among them, in comminuted fractures of anterior maxillary wall, multiple depressed and impacted bony segments cannot be reduced easily when performing internal fixation using plates and screws or wires, and inadequate restoration leads to a range of complications. This paper introduces an alternative technique using a resorbable mesh with fibrin glue to restore comminuted fractures of anterior maxillary wall...
September 2018: Archives of Craniofacial Surgery
https://www.readbyqxmd.com/read/30233739/iliac-bone-biopsy-complicated-by-hematoma-hemostasis-achieved-with-glue-injection
#15
Robert Pugh, Bryan Wessel, Omar S Zuberi, Martin S Vyleta
Serious hemorrhage after a bone biopsy is a rare complication of the procedure. Due to the infrequency of this complication, there is limited literature available regarding the treatment. Here, we present a case of a 70-year-old male who developed a symptomatic gluteal hematoma after an iliac bone lesion biopsy. Hemostasis was achieved by injecting an N-butyl cyanoacrylate glue solution into the bone cannulation site under CT-guidance.
December 2018: Radiology case reports
https://www.readbyqxmd.com/read/30220068/allergy-to-surgical-implants
#16
REVIEW
Karin A Pacheco
Surgical implants are essential elements of repair procedures to correct worn out joints, damaged spinal components, heart and vascular disease, and chronic pain. However, many of the materials that provide stability, flexibility, and durability to the implants are also immunogenic. Fortunately, allergic responses to surgical implants are infrequent. When they do occur, however, the associated pain, swelling, inflammation, and decreased range of motion can significantly impair the implant function. Given the high numbers of joint replacements performed in the developed world, allergic reactions to orthopedic implants form the largest category of allergic responses...
September 15, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/30187637/comparison-of-the-regenerative-effect-of-adipose-derived-stem-cells-fibrin-glue-scaffold-and-autologous-bone-graft-in-experimental-mandibular-defect-in-rabbit
#17
Davood Mehrabani, Azizollah Khodakaram-Tafti, Hanieh Shaterzadeh-Yazdi, Barbad Zamiri, Mahsa Omidi
BACKGROUND/AIMS: One of the main concerns for maxillofacial and orthopedic surgeons is finding a method to improve regeneration of large craniofacial bone defects. The aim of this study was to investigate the healing and regenerative effects of fibrin glue associated with adipose-derived stem cells (ADSCs) and fibrin glue scaffold alone with autologous bone grafts in experimental mandibular defects of the rabbit. METHODS: Bilateral uni-cortical osteotomies were performed in the mandible of 20 male Dutch rabbits...
September 6, 2018: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/30011257/therapeutic-efficacy-of-spherical-aggregated-human-bone-marrow-derived-mesenchymal-stem-cells-cultured-for-osteochondral-defects-of-rabbit-knee-joints
#18
Byung Hoon Lee, Jong Nam Park, Eun Ju Lee, Young Wan Moon, Joon Ho Wang
BACKGROUND: Engraftment and longevity of transplanted cells are crucial for stem cell-based cartilage treatment. PURPOSE: To determine whether cultured spherical cell masses of human bone marrow-derived mesenchymal stem cells (hBM-MSCs) could improve engraftment at defect sites and to examine their corresponding effects on osteochondral regeneration. STUDY DESIGN: Controlled laboratory study. METHODS: A cylindrical osteochondral defect (5 mm wide × 5 mm deep) was created in trochlear grooves of rabbit knees...
July 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29995003/round-window-occlusion-affects-bone-conduction-in-cadaver-heads
#19
Keguang Chen, Huiying Lyu, Dongming Yin, Lin Yang, Tianyu Zhang, Peidong Dai
OBJECTIVE: To explore the feasibility of ear mold glue in the molding of round window occlusion (RWO) in cadaver heads and to study the effect on bone conduction (BC). METHODS: Ten cadaver heads were selected to establish RWO model. Ear mold glue was used to immobilize round window niche. The vibration properties of the stapes footplate (VST) in response to the acoustic stimulation, and the vibration properties of the stapes footplate and cochlear promontory (VCP) in response to the B-71 stimulation were assessed by laser Doppler vibrometer in both pre-RWO and post-RWO...
August 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29872877/-children-collect-bones-teaching-aids-and-propaganda-material-on-bone-collections-and-bone-utilisation-used-in-german-schools-during-the-third-reich
#20
Elisabeth Vaupel, Florian Preiß
In the nineteenth and early twentieth centuries bones were an essential raw material for the German chemical industry, vital to the production of fertilizer, glue, gelatine, soap and other products. As most of this material was imported, the German school system during the "Third Reich" took the utilisation of bones as an example to illustrate the relevance of the four-year plan of 1936 and its policy of economic self-sufficiency. The school children were encouraged to collect bones from domestic sources and bring them to the collecting points in the schools...
June 5, 2018: NTM
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