Tae-Young Kim, Anna Kim, Yam Prasad Aryal, Shijin Sung, Elina Pokharel, Sanjiv Neupane, So-Young Choi, Jung-Hong Ha, Jae-Kwang Jung, Hitoshi Yamamoto, Chang-Hyeon An, Jo-Young Suh, Wern-Joo Sohn, Youngkyun Lee, Il-Ho Jang, Derek D Norman, Gabor J Tigyi, Seo-Young An, Jae-Young Kim
Lipid biosynthesis is recently studied its functions in a range of cellular physiology including differentiation and regeneration. However, it still remains to be elucidated in its precise function. To reveal this, we evaluated the roles of lysophosphatidic acid (LPA) signaling in alveolar bone formation using the LPA type 2 receptor (LPAR2) antagonist AMG-35 (Amgen Compound 35) using tooth loss without periodontal disease model which would be caused by trauma and usually requires a dental implant to restore masticatory function...
January 2024: Journal of Cellular Physiology