keyword
https://read.qxmd.com/read/37904091/neurobiological-mechanisms-of-ect-and-tms-treatment-in-depression-study-protocol-of-a-multimodal-magnetic-resonance-investigation
#21
JOURNAL ARTICLE
Leila Marie Frid, Ute Kessler, Olga Therese Ousdal, Åsa Hammar, Jan Haavik, Frank Riemer, Marco Hirnstein, Lars Ersland, Vera Jane Erchinger, Eivind Haga Ronold, Gyrid Nygaard, Petter Jakobsen, Alexander R Craven, Berge Osnes, Renata Alisauskiene, Hauke Bartsch, Stephanie Le Hellard, Anne-Kristin Stavrum, Ketil J Oedegaard, Leif Oltedal
BACKGROUND: Noninvasive neurostimulation treatments are increasingly being used to treat major depression, which is a common cause of disability worldwide. While electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) are both effective in treating depressive episodes, their mechanisms of action are, however, not completely understood. ECT is given under general anesthesia, where an electrical pulse is administered through electrodes placed on the patient's head to trigger a seizure...
October 30, 2023: BMC Psychiatry
https://read.qxmd.com/read/37845431/brain-tissue-oxygen-and-bold-fmri-under-different-levels-of-neuronal-activity
#22
JOURNAL ARTICLE
D P Aksenov, K Rutila, L Li, M J Miller, D A Gascoigne, N A Serdyukova, E D Doubovikov, R A Linsenmeier, A Drobyshevsky
Localized increases in neuronal activity are supported by the hemodynamic response, which delivers oxygen to the brain tissue to support synaptic functions, action potentials and other neuronal processes. However, it remains unknown if changes in baseline neuronal activity, which are expected to reflect neuronal metabolic demand, alter the relationship between the local hemodynamic and oxygen behaviour. In order to better characterize this system, we examine here the relationship between brain tissue oxygen (PO2 ) and hemodynamic responses (BOLD functional MRI) under different levels of neuronal activity...
2023: Advances in Experimental Medicine and Biology
https://read.qxmd.com/read/37790816/carpal-tunnel-release-with-ultrasound-guidance-intermediate-term-clinical-outcomes-and-magnetic-resonance-imaging-findings
#23
JOURNAL ARTICLE
Grace E Nicholas, Jen Galloway, Jennifer Hawley, Joseph C McGinley
PURPOSE: The purpose of this study was to report intermediate-term outcomes following carpal tunnel release using ultrasound guidance and wide-awake local anesthesia no tourniquet, including a subset of patients with preoperative and postoperative magnetic resonance imaging (MRI). METHODS: In this observational study, patients with carpal tunnel syndrome were treated with carpal tunnel release using ultrasound guidance and wide-awake local anesthesia no tourniquet in a procedure room at a single center...
September 2023: Journal of hand surgery global online
https://read.qxmd.com/read/37762729/clinical-outcomes-and-quality-of-life-after-patent-foramen-ovale-pfo-closure-in-patients-with-stroke-transient-ischemic-attack-of-undetermined-cause-and-other-pfo-associated-clinical-conditions-a-single-center-experience
#24
JOURNAL ARTICLE
Salvatore Evola, Emmanuele Antonio Camarda, Oreste Fabio Triolo, Daniele Adorno, Alessandro D'Agostino, Giuseppina Novo, Eustaquio Maria Onorato
INTRODUCTION: The aim of this study was to assess clinical outcomes and quality of life after PFO closure in patients with previous stroke/TIA of undetermined cause and in patients with other complex PFO-associated clinical conditions. METHODS: Between July 2009 and December 2019 at our University Cardiology Department, 118 consecutive patients underwent a thorough diagnostic work-up including standardized history taking, clinical evaluation, full neurological examination, screening for thrombophilia, brain magnetic resonance imaging (MRI), ultrasound-Doppler sonography of supra-aortic vessels and 24 h ECG Holter monitoring...
September 5, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37738120/in%C3%A2-vivo-functional-brain-mapping-using-ultra-high-field-fmri-in-awake-common-marmosets
#25
JOURNAL ARTICLE
Alessandro Zanini, Audrey Dureux, Azadeh Jafari, Kyle M Gilbert, Peter Zeman, Miranda Bellyou, Alex Li, Cheryl Vander Tuin, Stefan Everling
The common marmoset (Callithrix jacchus) is gaining attention in the field of cognitive neuroscience. The development of an effective protocol for fMRI data acquisition in awake marmosets is a key factor in developing reliable comparative studies. Here, we describe a protocol to obtain fMRI data in awake marmosets using auditory and visual stimulation. We describe steps for surgical and anesthesia procedures, MRI training, and positioning the marmosets within an MRI-compatible body restraint. We then detail fMRI scanning and preprocessing of functional images...
September 21, 2023: STAR protocols
https://read.qxmd.com/read/37728441/computed-tomography-measured-epicardial-adipose-tissue-and-psoas-muscle-attenuation-new-biomarkers-to-predict-major-adverse-cardiac-events-mace-and-mortality-in-patients-with-heart-disease-and-critically-ill-patients-part-i-epicardial-adipose-tissue
#26
JOURNAL ARTICLE
Jeroen Walpot, Paul Van Herck, Caroline M Van de Heyning, Johan Bosmans, Samia Massalha, Manu L N G Malbrain, Hein Heidbuchel, João R Inácio
Over the last two decades, the potential role of epicardial adipocyte tissue (EAT) as a marker for major adverse cardiovascular events has been extensively studied. Unlike other visceral adipocyte tissues (VAT), EAT is not separated from the adjacent myocardium by a fascial layer and shares the same microcirculation with the myocardium. Adipocytokines, secreted by EAT, interact directly with the myocardium through paracrine and vasocrine pathways. The role of the Randle cycle, linking VAT accumulation to insulin resistance, and the relevance of blood flow and mitochondrial function of VAT, are briefly discussed...
2023: Anaesthesiology Intensive Therapy
https://read.qxmd.com/read/37712335/anesthesia-related-brain-microstructure-modulations-detected-by-diffusion-magnetic-resonance-imaging
#27
JOURNAL ARTICLE
Thomas Beck Lindhardt, Christian Stald Skoven, Luca Bordoni, Leif Østergaard, Zhifeng Liang, Brian Hansen
Recent studies have shown significant changes to brain microstructure during sleep and anesthesia. In vivo optical microscopy and magnetic resonance imaging (MRI) studies have attributed these changes to anesthesia and sleep-related modulation of the brain's extracellular space (ECS). Isoflurane anesthesia is widely used in preclinical diffusion MRI (dMRI) and it is therefore important to investigate if the brain's microstructure is affected by anesthesia to an extent detectable with dMRI. Here, we employ diffusion kurtosis imaging (DKI) to assess brain microstructure in the awake and anesthetized mouse brain (n = 22)...
September 15, 2023: NMR in Biomedicine
https://read.qxmd.com/read/37707861/feasibility-and-implementation-of-a-4d-free-breathing-variable-density-stack-of-stars-functional-magnetic-resonance-urography-in-young-children-without-sedation
#28
JOURNAL ARTICLE
Jakob Spogis, Christoph Katemann, Shuo Zhang, Michael Esser, Ilias Tsiflikas, Jürgen Schäfer
BACKGROUND: Functional magnetic resonance urography (MRU) is well established in the diagnostic workup of urinary tract anomalies in children, providing comprehensive morphological and functional information. However, dynamic contrast-enhanced images acquired in the standard Cartesian k-space manner are prone to motion artifacts. A newly introduced 4D high spatiotemporal resolution dynamic contrast-enhanced magnetic resonance imaging based on variable density elliptical centric radial stack-of-stars sharing technique has shown improved image quality regarding motions under free breathing...
September 15, 2023: Investigative Radiology
https://read.qxmd.com/read/37700753/generation-of-a-whole-brain-hemodynamic-response-function-and-sex-specific-differences-in-cerebral-processing-of-mechano-sensation-in-mice-detected-by-bold-fmri
#29
JOURNAL ARTICLE
Hui-Fen Chen, Henriette Lambers, Nina Nagelmann, Martin Sandbrink, Daniel Segelcke, Esther Pogatzki-Zahn, Cornelius Faber, Bruno Pradier
BOLD fMRI has become a prevalent method to study cerebral sensory processing in rodent disease models, including pain and mechanical hypersensitivity. fMRI data analysis is frequently combined with a general-linear-model (GLM) -based analysis, which uses the convolution of a hemodynamic response function (HRF) with the stimulus paradigm. However, several studies indicated that the HRF differs across species, sexes, brain structures, and experimental factors, including stimulation modalities or anesthesia, and hence might strongly affect the outcome of BOLD analyzes...
2023: Frontiers in Neuroscience
https://read.qxmd.com/read/37664278/non-functioning-pituitary-macroadenoma-resection-in-twin-pregnancy-a-case-report
#30
Anup Bista, Dipesh Mishra, Suson Ghimire, Prakriti Bhandari, Sudan Puri
Non-functioning pituitary adenomas (NFPAs) are rare in females of reproductive age. We present the case of a 37-year-old pregnant woman in her second trimester with a diagnosis of symptomatic pituitary macroadenoma with twin pregnancy. Magnetic resonance imaging (MRI) confirmed a well-defined macroadenoma compressing the optic chiasm, thus necessitating surgery. The patient underwent transnasal transsphenoidal resection of the tumor under general anesthesia. Anesthesia management posed challenges due to concurrent considerations of pregnancy and neurosurgery...
August 2023: Curēus
https://read.qxmd.com/read/37652419/application-value-of-magnetic-resonance-imaging-medical-technology-in-the-perioperative-management-of-brain-gliomas-impact-on-anesthesia-and-prognosis
#31
JOURNAL ARTICLE
Jing Cui, Lan Yao, Changyu Lu, Zongsheng Xu, Lunxu Li
OBJECTIVE: To assess the utility of magnetic resonance imaging (MRI) medical technology in the perioperative management of brain gliomas and its impact on anesthesia and prognosis. METHODS: An observational, retrospective comparative study was conducted. We selected 60 patients who underwent glioma resection at our hospital from January 2019 to January 2020. Patients were divided into two groups based on admission order: the experimental group (EG) and the control group (CG), with 30 cases each...
September 1, 2023: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/37639306/rapidly-deteriorating-degenerative-cervical-myelopathy-following-ventricular-shunt-revision-for-hydrocephalus-case-report
#32
Tanzil Rujeedawa, Oliver Mowforth, Mark Kotter, Benjamin Davies
A female patient in her early 40s presented with a several-month history of gait unsteadiness and dragging her left leg. She had a background of congenital hydrocephalus, treated with a ventriculoatrial shunt. On examination, she had increased tone and brisk reflexes in the lower limbs and a positive Hoffmann sign. A computed tomography (CT) scan and shunt series x-rays identified hydrocephalus secondary to a disconnected shunt. Magnetic resonance imaging (MRI) of her cervical spine was also performed as part of the workup for her presenting symptoms and demonstrated features compatible with degenerative cervical myelopathy (DCM)...
August 28, 2023: Interactive Journal of Medical Research
https://read.qxmd.com/read/37582301/spatial-and-spectral-components-of-the-bold-global-signal-in-rat-resting-state-functional-mri
#33
JOURNAL ARTICLE
Nmachi Anumba, Eric Maltbie, Wen-Ju Pan, Theodore J LaGrow, Nan Xu, Shella Keilholz
PURPOSE: In resting-state fMRI (rs-fMRI), the global signal average captures widespread fluctuations related to unwanted sources of variance such as motion and respiration, as well as widespread neural activity; however, relative contributions of neural and non-neural sources to the global signal remain poorly understood. This study sought to tackle this problem through the comparison of the BOLD global signal to an adjacent non-brain tissue signal, where neural activity was absent, from the same rs-fMRI scan obtained from anesthetized rats...
December 2023: Magnetic Resonance in Medicine
https://read.qxmd.com/read/37405456/cardiac-magnetic-resonance-imaging-to-determine-single-ventricle-function-in-a-pediatric-population-is-feasible-in-a-large-trial-setting-experience-from-the-single-ventricle-reconstruction-trial-longitudinal-follow-up
#34
JOURNAL ARTICLE
Jon Detterich, Michael D Taylor, Timothy C Slesnick, Michael DiLorenzo, Anthony Hlavacek, Christopher Z Lam, Shagun Sachdeva, Sean M Lang, M Jay Campbell, Jennifer Gerardin, Kevin K Whitehead, Rahul H Rathod, Mark Cartoski, Shaji Menon, Felicia Trachtenberg, Russell Gongwer, Jane Newburger, Caren Goldberg, Adam L Dorfman
The Single Ventricle Reconstruction (SVR) Trial was a randomized prospective trial designed to determine survival advantage of the modified Blalock-Taussig-Thomas shunt (BTTS) vs the right ventricle to pulmonary artery conduit (RVPAS) for patients with hypoplastic left heart syndrome. The primary aim of the long-term follow-up (SVRIII) was to determine the impact of shunt type on RV function. In this work, we describe the use of CMR in a large cohort follow up from the SVR Trial as a focused study of single ventricle function...
July 5, 2023: Pediatric Cardiology
https://read.qxmd.com/read/37377015/transcranial-direct-current-stimulation-reverses-stroke-induced-network-alterations-in-mice
#35
JOURNAL ARTICLE
Stefan J Blaschke, Susan Vlachakis, Niklas Pallast, Helene L Walter, Lukas J Volz, Dirk Wiedermann, Gereon R Fink, Mathias Hoehn, Markus Aswendt, Michael Schroeter, Maria A Rueger
BACKGROUND: Beyond focal effects, stroke lesions impact the function of distributed networks. We here investigated (1) whether transcranial direct current stimulation (tDCS) alters the network changes induced by cerebral ischemia and (2) whether functional network parameters predict the therapeutic efficacy of tDCS in a mouse model of focal photothrombotic stroke. METHODS: Starting 3 days after stroke, cathodal tDCS (charge density=39.6 kC/m²) was applied over 10 days in male C57Bl/6J mice under light anesthesia over the lesioned sensory-motor cortex...
August 2023: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/37311324/atypical-intradural-extramedullary-spinal-schwannoma-causing-cauda-equina-syndrome-a-case-report-and-literature-review
#36
Dong-Ju Lim
INTRODUCTION: Spinal schwannomas are slow-growing benign tumors that are generally asymptomatic. However, we describe an atypical case in which an intradural extramedullary schwannoma presented as an acute cauda equina syndrome. PRESENTATION OF CASE: This was a 58-year-old woman with a 2-month history of severe low back pain and worsening neurological deficits and a 2-day period of acute onset of lower extremity numbness and urinary incontinence. Physical and neurological examination revealed significant lower extremity weakness, tenderness on palpation of the spine, positive straight leg test bilaterally, decreased sensation below the L4 dermatome, reduced sphincter tone, saddle anesthesia, decreased deep tendon reflexes, and loss of sphincter control, consistent with compression of the cauda equina...
June 10, 2023: International Journal of Surgery Case Reports
https://read.qxmd.com/read/37259903/technical-notes-and-clinical-outcomes-of-full-endoscopic-interbody-fusion-via-transforaminal-approach-for-hard-disc-herniations-in-thoracolumbar-junction
#37
JOURNAL ARTICLE
Zheng Cao, Zhen-Zhou Li, Hong-Liang Zhao, Jia-Liang Zhu, Shu-Xun Hou
OBJECTIVE: Obtaining sufficient decompression and solid fusion and avoiding approach-related injuries simultaneously are still challenging for the treatment of hard disc herniation in thoracolumbar junction. A combined full-endoscopic decompression and interbody fusion via a transforaminal approach was used to achieve this goal. The purpose of this study was to introduce the technical notes and clinical outcomes of this novel technique. METHODS: Twenty segments of hard disc herniations in the thoracolumbar junction of 14 patients treated with full-endoscopic interbody fusion via the transforaminal approach between January 2018 and September 2021 were analyzed...
June 1, 2023: Orthopaedic Surgery
https://read.qxmd.com/read/37140648/stereotactic-robot-assisted-mri-guided-laser-interstitial-thermal-therapy-thalamotomy-for-medically-intractable-parkinson-s-disease-tremor-technical-note-and-preliminary-effects-on-2-cases
#38
JOURNAL ARTICLE
Mickael Aubignat, Mélissa Tir, Martial Ouendo, Jean-Marc Constans, Michel Lefranc
BACKGROUND: Medically intractable Parkinson's disease (PD) tremor is a common difficult clinical situation with major impact on patient's quality of life (QOL). Deep brain stimulation (DBS) is an effective therapy but is not an option for many patients. Less invasive lesional brain surgery procedures, such as thalamotomy, have proven to be effective in these indications. Here, we describe the technical nuances and advantages of stereotactic robot-assisted MRI-guided laser interstitial thermal therapy (MRIg-LITT) thalamotomy for medically intractable PD tremor...
June 2023: Acta Neurochirurgica
https://read.qxmd.com/read/37098063/parvalbumin-interneuron-activity-drives-fast-inhibition-induced-vasoconstriction-followed-by-slow-substance-p-mediated-vasodilation
#39
JOURNAL ARTICLE
Thanh Tan Vo, Geun Ho Im, Kayoung Han, Minah Suh, Patrick J Drew, Seong-Gi Kim
The role of parvalbumin (PV) interneurons in vascular control is poorly understood. Here, we investigated the hemodynamic responses elicited by optogenetic stimulation of PV interneurons using electrophysiology, functional magnetic resonance imaging (fMRI), wide-field optical imaging (OIS), and pharmacological applications. As a control, forepaw stimulation was used. Stimulation of PV interneurons in the somatosensory cortex evoked a biphasic fMRI response in the photostimulation site and negative fMRI signals in projection regions...
May 2, 2023: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/37095440/ultrasonographic-images-of-spina-bifida-before-obstetric-anesthesia-a-case-series
#40
JOURNAL ARTICLE
Mayuko Doi, Yasuyoshi Sakurai, Daisuke Sakamaki, Soichiro Tanaka, Nobuyuki Katori, Shoichi Uezono
BACKGROUND: Spina bifida is a relatively common congenital malformation. As the functional prognosis of patients with spina bifida has improved over time, the number of cases resulting in pregnancy and delivery has increased. Lumbar ultrasonography has become a standard and helpful technique before neuraxial anesthesia. We believe that it might be valuable if we use lumbar ultrasonography to evaluate pregnant women with spina bifida before obstetric anesthesia. CASE PRESENTATION: We performed lumbar ultrasonography to evaluate four pregnant women with spina bifida...
April 24, 2023: BMC Anesthesiology
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