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Vitamin AND D AND Testosterone

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https://www.readbyqxmd.com/read/30074968/monitoring-blood-biomarkers-and-training-load-throughout-a-collegiate-soccer-season
#1
Robert A Huggins, Andrea R Fortunati, Ryan M Curtis, David P Looney, Chris A West, Elaine C Lee, Maren S Fragala, Mathew L Hall, Douglas J Casa
Huggins, RA, Fortunati, AR, Curtis, RM, Looney, DP, West, CA, Lee, EC, Fragala, MS, Hall, ML, and Casa, DJ. Monitoring blood biomarkers and training load throughout a collegiate soccer season. J Strength Cond Res XX(X): 000-000, 2018-This observational study aimed to characterize the responses of a comprehensive panel of biomarkers, observed ranges, training load (TL) metrics, and performance throughout the collegiate soccer season (August-November). Biomarkers (n = 92) were collected before the start of pre-season (PS), in-season weeks (W)1, W4, W8, and W12 in NCAA Division I male soccer players (n = 20, mean ± SD; age = 21 ± 1 years, height = 180 ± 6 cm, body mass = 78...
August 2, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/30047068/pharmacological-interventions-to-improve-muscle-mass-muscle-strength-and-physical-performance-in-older-people-an-umbrella-review-of-systematic-reviews-and-meta-analyses
#2
REVIEW
Anton De Spiegeleer, David Beckwée, Ivan Bautmans, Mirko Petrovic
BACKGROUND: Sarcopenia, defined as the pathological decline in muscle mass, muscle strength and physical performance with aging, has become one of the geriatric giants because of its increasing prevalence and devastating health effects. The Belgian Society of Gerontology and Geriatrics (BSGG) is currently developing evidence-based guidelines for the prevention and therapy of sarcopenia for use in broad clinical practice. This systematic review summarizes the results of the Working Group on Pharmacology...
July 25, 2018: Drugs & Aging
https://www.readbyqxmd.com/read/30034922/interfacing-complex-laboratory-instruments-during-a-change-to-epic-beaker
#3
Gregory David Scott, Cary Schrandt, Chandler C Ho, Michael C Chung, Daniel Zhou, Run Zhang Shi
Background: Implementing a laboratory-developed test sometimes requires incorporating an unconventional device into the laboratory information system (LIS) and customizing an interface to reduce transcription error and improve turnaround time. Such a custom interface is a necessity for complicated high-volume tests such as 25-OH Vitamin D by liquid chromatography-tandem mass spectrometry (LC-MS/MS) when there is no vendor-or LIS-supplied interface available. Here, we describe our work and experience interfacing a API 5000 LC-MS/MS instrument with our newly implemented LIS, Epic Beaker, using a combination of in-house scripting software and a middleware vendor, Data Innovations...
2018: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/30019416/independent-association-of-serum-vitamin-d-with-anti-mullerian-hormone-levels-in-women-with-polycystic-ovary-syndrome
#4
Ho Yan Queenie Wong, Hang Wun Raymond Li, Karen Siu Ling Lam, Sidney Tam, Chi Chung Shek, Chi Yan Vivian Lee, William Shu Biu Yeung, Pak Chung Ho, Ernest Hung Yu Ng
OBJECTIVE: This study aimed at investigating the association of serum vitamin D (25(OH)D) and anti-Mullerian hormone (AMH) levels in women with polycystic ovary syndrome (PCOS) as well as non-PCOS healthy ovulatory women and the possible confounding effects of adiposity and androgen. METHOD: This was a cross-sectional study conducted on serum samples collected from 451 women diagnosed with PCOS as well as 244 age-matched healthy ovulatory women in a tertiary gynaecology out-patient clinic and a family planning clinic...
July 18, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29982837/improvements-in-semen-quality-sperm-fatty-acids-and-reproductive-performance-in-aged-ross-breeder-roosters-fed-a-diet-supplemented-with-a-moderate-ratio-of-n-3-n-6-fatty-acids
#5
Reza Safari Asl, Farid Shariatmadari, Mohsen Sharafi, Mohammad Amir Karimi Torshizi, Abdolhossein Shahverdi
The purpose of this study was to evaluate the effects of dietary n-3: n-6 fatty acid (FA) ratios and vitamin E (vitE) on the semen quality, FA composition, hormonal responses, and reproductive performance of aged roosters. Thirty-six Ross broiler breeder roosters were assigned to a 3 × 2 factorial design with 3 n-3: n-6 FA ratios (0.09, 0.16, and 0.23) based on the inclusion of 3 oil sources (canola, canola/fish, and fish) and 2 vitE levels (0 and 200 mg/kg). During the 60 d of treatment, semen parameters, FAs composition of sperm, lipid peroxidation, and hormonal responses were monitored...
July 3, 2018: Poultry Science
https://www.readbyqxmd.com/read/29942920/suspected-testosterone-producing-tumor-in-a-patient-taking-biotin-supplements
#6
Heather M Stieglitz, Nichole Korpi-Steiner, Brooke Katzman, Jennifer E Mersereau, Maya Styner
A perimenopausal woman presented with palpitations, hirsutism, and inability to lose weight. Laboratory tests revealed an unusual endocrine hormonal profile including pituitary hormones (TSH, ACTH, and prolactin) below reference intervals and gonadal (testosterone) and adrenal (cortisol) hormones above reference intervals. Ultimately, after a comprehensive workup including a scheduled surgical procedure, abnormal laboratories were determined due to biotin interference. Biotin (vitamin B7) is a water-soluble vitamin and essential cofactor for the metabolism of fatty acids, glucose, and amino acids...
June 1, 2018: Journal of the Endocrine Society
https://www.readbyqxmd.com/read/29927841/association-between-sex-hormones-and-ambulatory-blood-pressure
#7
Monik C Jiménez, Lu Wang, Julie E Burnig, JoAnn E Manson, John P Forman, Howard D Sesso
INTRODUCTION: Higher levels of total testosterone and lower levels of sex hormone-binding globulin (SHBG) have been associated with increased blood pressure (BP) in women with an inverse association between total testosterone and BP among men. Fewer studies have examined associations with 24-h ambulatory blood pressure (ABP), blunted nocturnal BP decline or the role of dehydroepiandrosterone sulfate (DHEAS), a precursor to androgens. METHODS: Baseline blood samples were assayed for 229 normotensive men (≥50 years) and women (≥55 years) participating in the VITamin D and OmegA-3 TriaL...
June 20, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29892563/prevalence-of-hypovitaminosis-d-and-its-association-with-hypoadiponectinemia-and-hyperfollistatinemia-in-saudi-women-with-na%C3%A3-ve-polycystic-ovary-syndrome
#8
Osama Adnan Kensara
Aims: The association between vitamin D and polycystic ovary syndrome (PCOS) is an active area of growing research. However, data in Saudi Arabia are scarce. This study aimed to define serum 25-hydroxyvitamin D (25(OH)D) levels among Saudi women with naïve PCOS, and to investigate the associations of their 25(OH)D status with their serum adiponectin and follistatin levels, along with indices of insulin resistance and hormonal deteriorations. Methods: In this case-control observational study, 63 women with PCOS and 65 age-and body mass index (BMI)-matched control women were assessed...
June 2018: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/29859385/the-influences-of-vitamin-d-and-omega-3-co-supplementation-on-clinical-metabolic-and-genetic-parameters-in-women-with-polycystic-ovary-syndrome
#9
Mehri Jamilian, Mansooreh Samimi, Naghmeh Mirhosseini, Faraneh Afshar Ebrahimi, Esmat Aghadavod, Rezavan Talaee, Sadegh Jafarnejad, Shahrzad Hashemi Dizaji, Zatollah Asemi
OBJECTIVE: The aim of this study was to evaluate the effect of the co-administration of vitamin D and omega-3 fatty acid on clinical, metabolic and genetic parameters in women with polycystic ovary syndrome (PCOS). METHODS: This randomized, double-blinded, placebo-controlled clinical trial was conducted on 60 subjects, aged 18-40 years old with PCOS. Subjects were randomly allocated to take either 50,000 IU vitamin D every 2 weeks plus 2000 mg/day omega-3 fatty acid from fish oil (n = 30) or placebo (n = 30) for 12 weeks...
October 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29765521/long-term-deficiency-of-vitamin-d-in-germ-cell-testicular-cancer-survivors
#10
Lucia Nappi, Margaret Ottaviano, Pasquale Rescigno, Ladan Fazli, Martin E Gleave, Vincenzo Damiano, Sabino De Placido, Giovannella Palmieri
Background: Cisplatin-based chemotherapy significantly improved the survival of patients with germ cell testicular cancer. However, long term side effects of chemotherapy have non-negligible impact on the quality of life of these young patients, who have a long life expectancy after being successfully treated. Materials and Methods: 25-OH vitamin D, testosterone, FSH and LH of patients with testicular cancer were retrospectively evaluated and for each patient clinical information were collected...
April 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29745981/evaluation-of-biochemical-endocrine-and-metabolic-biomarkers-for-the-early-diagnosis-of-polycystic-ovary-syndrome-among-non-obese-saudi-women
#11
Maha H Daghestani
OBJECTIVE: To investigate the potential of selected biochemical, endocrine, and metabolic biomarkers for early diagnosis of polycystic ovary syndrome (PCOS) among non-obese women. METHODS: A prospective observational cross-sectional study was conducted at three medical centers in Makkah, Saudi Arabia, between July 15 and September 20, 2017. Eligible participants were non-obese women diagnosed with PCOS according to the Rotterdam criteria (n=44) and non-obese normo-ovulatory women without signs of PCOS (control group; n=44)...
August 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29745000/impact-of-serum-25-oh-vitamin-d-level-on-lower-urinary-tract-symptoms-in-men-a-step-towards-reducing-overactive-bladder
#12
Sangjun Yoo, Sohee Oh, Hyung Suk Kim, Han Seok Choi, Juhyun Park, Sung Yong Cho, Hwancheol Son, Hyeon Jeong, Hae Won Lee, Min Chul Cho
OBJECTIVES: To evaluate the impact of serum vitamin D level on male lower urinary tract symptoms (LUTS). PATIENTS AND METHODS: Men with LUTS who visited the outpatient clinic of the urology department at one of two hospitals between March 2014 and April 2017 were eligible for inclusion in the study. The impact of vitamin D on LUTS was evaluated using multivariate analysis to adjust for age, body mass index, prostate-specific antigen, testosterone, glycated haemoglobin, physical activity and prostate volume...
May 9, 2018: BJU International
https://www.readbyqxmd.com/read/29683475/pharmacological-interventions-for-the-prevention-of-insufficiency-fractures-and-avascular-necrosis-associated-with-pelvic-radiotherapy-in-adults
#13
REVIEW
Qurrat U van den Blink, Kate Garcez, Caroline C Henson, Susan E Davidson, Claire E Higham
BACKGROUND: Pelvic radiotherapy is a treatment delivered to an estimated 150,000 to 300,000 people annually across high-income countries. Fractures due to normal stresses on weakened bone due to radiotherapy are termed insufficiency fractures. Pelvic radiotherapy-related interruption of the blood supply to the hip is termed avascular necrosis and is another recognised complication. The reported incidences of insufficiency fractures are 2.7% to 89% and risk of developing avascular necrosis is 0...
April 23, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29669566/apa-i-polymorphism-in-vdr-gene-is-related-to-metabolic-syndrome-in-polycystic-ovary-syndrome-a-cross-sectional-study
#14
Betânia Rodrigues Santos, Sheila Bunecker Lecke, Poli Mara Spritzer
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrine disorder determined by polygenic traits as well as environmental factors. Lower vitamin D levels have been detected in PCOS women and related to hormone and metabolic disturbances. Vitamin D acts in tissues through the vitamin D receptor (VDR). VDR gene variants have been associated with worse metabolic profile in the general population. We investigated the genotype and haplotype distribution of the Bsm-I (rs1544410), Apa-I (rs7975232), and Taq-I (rs731236) VDR gene polymorphisms in PCOS and non-hirsute women from southern Brazil...
April 18, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/29560610/investigating-the-effect-of-testosterone-by-itself-and-in-combination-with-letrozole-on-1-25-dihydroxy-vitamin-d-and-fgf23-in-male-rats
#15
F Saki, S R Kasaee, F Sadeghian, F Koohpeyma, G H R Omrani
BACKGROUND: Testosterone deficiency might be associated with vitamin D levels in hypogonadal men, but it is not clear whether testosterone can affect vitamin D and fibroblast growth factor-23 (FGF23), either directly or indirectly via aromatization to estradiol. We aimed to investigate the role of testosterone on vitamin D metabolism and serum FGF23 in male rats. METHODS: A total of 48 male rats were divided into 4 equal groups: sham; O, orchiectomy; O + T, orchiectomized rats treated with testosterone; and O + T + L, orchiectomized rats treated with combination of testosterone and letrozole...
March 20, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29548752/vitamin-d-is-associated-with-bioavailability-of-androgens-in-eumenorrheic-women-with-prior-pregnancy-loss
#16
Daniel L Kuhr, Lindsey A Sjaarda, Zeina Alkhalaf, Ukpebo R Omosigho, Matthew T Connell, Robert M Silver, Keewan Kim, Neil J Perkins, Tiffany L Holland, Torie C Plowden, Enrique F Schisterman, Sunni L Mumford
BACKGROUND: Prior studies have reported mixed results regarding relationships between vitamin D, androgens, and sex hormone-binding globulin in patients with polycystic ovary syndrome. However, less is known regarding these associations in eumenorrheic, premenopausal women. OBJECTIVE: Our objective was to study the relationships between serum vitamin D and androgen biomarkers in eumenorrheic women with a history of pregnancy loss who were attempting pregnancy. STUDY DESIGN: This was an analysis of a cohort of 1191 participants from the Effects of Aspirin in Gestation and Reproduction trial (2006-2012)...
June 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29546692/vitamin-d-supplementation-does-not-prevent-the-testosterone-decline-in-males-with-advanced-heart-failure-the-evita-trial
#17
Armin Zittermann, Jana B Ernst, Sylvana Prokop, Uwe Fuchs, Jens Dreier, Joachim Kuhn, Cornelius Knabbe, Heiner K Berthold, Ioanna Gouni-Berthold, Jan F Gummert, Jochen Börgermann, Stefan Pilz
PURPOSE: Observational studies indicate a positive association between circulating 25-hydroxyvitamin D (25OHD) and testosterone (T) concentrations. Because low 25OHD concentrations and T deficiency are considered to be a generalized phenomenon in patients with advanced heart failure (HF), we aimed to investigate whether vitamin D supplementation has beneficial effects on T indices in these patients. METHODS: In a pre-specified secondary analysis of the EVITA (effect of vitamin D on mortality in heart failure) randomized controlled trial, we analyzed in male subjects with 25OHD concentrations < 75 nmol/L the effect of a daily vitamin D3 supplement of 4000 IU for 3 years (n = 71) vs...
March 15, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29535939/a-prospective-observational-study-of-osteoporosis-in-men
#18
Narendra Kotwal, Vimal Upreti, Amit Nachankar, K V S Hari Kumar
Context: The number of men afflicted with osteoporosis is unknown. Aims: This study aims to determine the prevalence of osteoporosis in men. Settings and Design: This was a prospective, observational study. Subjects and Methods: A total of 200 male attendants of patients attending endocrine outpatient department and who were >55 years were recruited for the study. All the patients with osteopenia and osteoporosis were advised lifestyle interventions, supplementation with calcium carbonate (1000-1500 mg/day) and 25-hydroxyl-Vitamin D (400-600 IU/day) and bisphosphonates if indicated...
January 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29531528/vitamin-d-and-male-sexual-function-a-transversal-and-longitudinal-study
#19
Giacomo Tirabassi, Maurizio Sudano, Gianmaria Salvio, Melissa Cutini, Giovanna Muscogiuri, Giovanni Corona, Giancarlo Balercia
Background: The effects of vitamin D on sexual function are very unclear. Therefore, we aimed at evaluating the possible association between vitamin D and sexual function and at assessing the influence of vitamin D administration on sexual function. Methods: We retrospectively studied 114 men by evaluating clinical, biochemical, and sexual parameters. A subsample ( n = 41) was also studied longitudinally before and after vitamin D replacement therapy. Results: In the whole sample, after performing logistic regression models, higher levels of 25(OH) vitamin D were significantly associated with high values of total testosterone and of all the International Index of Erectile Function (IIEF) questionnaire parameters...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29527916/the-influence-of-testosterone-on-the-expression-and-function-of-vitamin-d-3-receptor-vdr-protein-in-the-porcine-ovarian-follicle
#20
M Herian, M R Luck, M Grzesiak
Recently it has been shown that vitamin D(3) acting via its cognate receptor (VDR) regulates the growth, differentiation and function of female reproductive tissues including ovary. The aim of the study was to examine the effect of testosterone (T) and its antagonist 2-hydroxyflutamide (HF) on VDR protein expression and function in porcine ovarian follicles. Medium size antral follicles expressing great amount of androgen receptors and represent high steroidogenic activity were used in this research. After 6 h incubation of whole follicles with T, HF or T+HF, immunohistochemical analysis of VDR revealed its nuclear localization in granulosa and theca interna cells in control and experimental groups...
July 17, 2018: Physiological Research
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