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https://www.readbyqxmd.com/read/30341660/surgical-considerations-in-a-paediatric-case-of-a-large-skull-base-epithelioid-haemangioendothelioma
#1
Suyi Ooi, Matthew Gutman, Chris Xenos, Ronil Chandra, Catriona McLean
Intracranial epithelioid haemangioendothelioma (EHE) is a rare intermediate grade vascular tumour with heterogeneous clinical and histopathological behaviour. We present the surgical considerations of an exceptionally large skull-based EHE in an 11-year old female who presented to our institution with headaches and a protuberance over the left parietal area. Magnetic resonance imaging (MRI) demonstrated a left sided 10.5 × 6.6 × 11.1 cm extra-axial tumour arising from the parieto-temporaloccipital region which was continuous with the calvarium...
October 19, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/30339049/treating-moderate-plaque-psoriasis-prospective-6-month-chart-review-of-patients-treated-with-apremilast
#2
Melissa L F Knuckles, Eugenia Levi, Jennifer Soung
PURPOSE: Apremilast, an oral phosphodiesterase 4 inhibitor, was effective in clinical trials in patients with moderate plaque psoriasis (affected body surface area [BSA] 5% to 10%). However, findings from real-world clinical practice are limited. MATERIALS AND METHODS: An online survey and chart review was conducted among US dermatologists during October 2015 to identify clinical characteristics and 6-month treatment outcomes among patients with moderate psoriasis treated with apremilast...
October 19, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/30338514/interventions-for-reducing-inflammation-in-familial-mediterranean-fever
#3
REVIEW
Bin Wu, Ting Xu, Youping Li, Xi Yin
BACKGROUND: Familial Mediterranean fever, a hereditary auto-inflammatory disease, mainly affects ethnic groups living in the Mediterranean region. Early studies reported colchicine as a potential drug for preventing attacks of familial Mediterranean fever. For those people who are colchicine-resistant or intolerant, drugs such as rilonacept, anakinra, canakinumab, etanercept, infliximab, thalidomide and interferon-alpha might be beneficial. This is an updated version of the review. OBJECTIVES: To evaluate the efficacy and safety of interventions for reducing inflammation in people with familial Mediterranean fever...
October 19, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/30338480/high-prevalence-of-adrenal-insufficiency-at-diagnosis-and-headache-recovery-in-surgically-resected-rathke-s-cleft-cysts-a-large-retrospective-single-center-study
#4
Fabienne Langlois, Anamaria Manea, Dawn Shao Ting Lim, Shirley McCartney, Christine G Yedinak, Justin S Cetas, Maria Fleseriu
BACKGROUND: Rathke's cleft cysts (RCC) are lesions that arise from Rathke's pouch. Though frequently incidental, resulting symptoms in a minority of cases are indicators for surgical resection, which may prove beneficial. OBJECTIVE: To characterize a cohort of surgically-resected RCC cases at Oregon Health & Science University; tabulate associated hormonal imbalances and symptoms, possible symptom reversal with surgery, determine recurrence risk; identify predictors of recurrence and headache improvement...
October 18, 2018: Endocrine
https://www.readbyqxmd.com/read/30337090/a-new-clinical-score-for-cranial-computed-tomography-in-emergency-department-non-trauma-patients-definition-and-first-validation
#5
Marcello Covino, Emanuele Gilardi, Alberto Manno, Benedetta Simeoni, Veronica Ojetti, Chiara Cordischi, Evelina Forte, Luigi Carbone, Simona Gaudino, Francesco Franceschi
INTRODUCTION: Well recognized guidelines are available for the use of cranial computed tomography (CCT) in traumatic patients, while no definitely accepted standards exists to for CCT in patients without history of head injury. The aim of this study is to propose an easy clinical score to stratify the need of CCT in emergency department (ED) patients with suspect non-traumatic intracranial pathology. METHODS: We retrospectively evaluated patients presenting to the ED for neurological deficit, postural instability, acute headache, altered mental status, seizures, confusion, dizziness, vertigo, syncope, and pre-syncope...
September 19, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/30335472/diagnostic-and-classification-tools-for-chronic-headache-disorders-a-systematic-review
#6
Rachel Potter, Katrin Probyn, Celia Bernstein, Tamar Pincus, Martin Underwood, Manjit Matharu
Background or aim Despite guidelines and the International Classification of Headache Disorders (ICHD-III beta) criteria, the diagnosis of common chronic headache disorders can be challenging for non-expert clinicians. The aim of the review was to identify headache classification tools that could be used by a non-expert clinician to classify common chronic disorders in primary care. Methods We conducted a systematic literature review of studies validating diagnostic and classification headache tools published between Jan 1988 and June 2016 from key databases: MEDLINE, ASSIA, Embase, Web of Knowledge and PsycINFO...
October 18, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/30334864/unique-stroke-symptoms-in-women-a-review
#7
Renee Colsch, Glenda Lindseth
BACKGROUND: Research suggests that there is a delay in recognizing unique stroke symptoms in women by both healthcare professionals and the general population. The purpose of this review was to identify and summarize the most relevant literature regarding recognition and assessment of unique stroke symptoms in women. METHODS: Literature review using PubMed, CINAHL, ERIC, MEDLINE, PsycINFO, and Google Scholar was used to search literature describing unique stroke symptoms...
October 16, 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/30334463/thunderclap-headache-an-update
#8
Chih-Wen Yang, Jong-Ling Fuh
Thunderclap headache (TCH) is an excruciating headache that reaches maximal intensity within a minute. It has numerous potential etiologies, the most concerning of which is subarachnoid hemorrhage (SAH) due to high morbidity and mortality. Thus, patients with TCH must be evaluated urgently to identify the underlying cause and initiate prompt therapy. Areas covered: This paper reviews PubMed-listed research articles and presents an update of the clinical features, diagnostic evaluation, and possible causes of TCH...
October 18, 2018: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/30332974/complications-of-immunoglobulin-therapy-and-implications-for-treatment-of-inflammatory-neuropathy-a-review
#9
Ahmed Abbas, Yusuf A Rajabally
Intravenous immunoglobulin (IVIg) forms a cornerstone of effective treatment for acute and chronic inflammatory neuropathies, with a class I evidence base in Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP) and multifocal motor neuropathy (MMN). It is generally considered to be a safe therapy however there are several recognised complications which are reviewed in this article. Most adverse events are immediate and mild such as headache, fever and nausea although more serious immediate reactions such as anaphylaxis may rarely occur...
October 17, 2018: Current Drug Safety
https://www.readbyqxmd.com/read/30332512/prevalence-predictive-factors-and-clinical-course-of-persistent-pain-associated-with-teeth-displaying-periapical-healing-following-non-surgical-root-canal-treatment-a-prospective-study
#10
R Philpott, K Gulabivala, R Leeson, Y-L Ng
AIMS: To investigate the prevalence, pain catastrophizing and other predictive factors, and clinical course of persistent pain/discomfort associated with teeth displaying periapical healing following non-surgical root canal treatment (NSRCT). METHODOLOGY: One-hundred-ninety-eight patients (264 teeth) who had NSRCT were reviewed at 5-14 months, post-operatively. Teeth with persistent post-treatment pain or discomfort, plus evidence of periapical healing were further monitored 0...
October 17, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/30328517/hemicrania-continua-a-clinical-perspective-on-diagnosis-and-management
#11
REVIEW
Amit Mehta, Priyanka Chilakamarri, Adeel Zubair, Deena E Kuruvilla
PURPOSE OF REVIEW: Hemicrania Continua (HC) is a daily and persistent form of headache that is characterized by side-locked pain which is continuous, varies in severity and can be associated with conjunctival injection, lacrimation, nasal congestion, rhinorrhea, eyelid edema, forehead or facial sweating and miosis and/or ptosis. RECENT FINDINGS: Functional imaging studies have shown activation of subcortical structures such as the posterior hypothalamus and dorsal rostral pons, which are known to disinhibit the trigeminal autonomic reflex, a reflex responsible for autonomic outflow through trigeminal efferents...
October 17, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/30328500/anti-neutrophil-cytoplasmic-antibody-associated-hypertrophic-cranial-pachymeningitis-and-otitis-media-a-review-of-literature
#12
REVIEW
Anquan Peng, Xinming Yang, Weijing Wu, Zian Xiao, Dinghua Xie, Shenglei Ge
BACKGROUND AND OBJECTIVE: It has been recognized that anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides may lead to hypertrophic pachymeningitis (HP) or intractable otitis media (OM). To our knowledge, few cases of coexistent ANCA-related HP and OM have been described previously. To increase awareness of this disease, we reviewed the literature describing patients with HP and intractable OM in a population with AAV to guide clinical decision making for otolaryngologists...
October 17, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/30327583/-albizia-adianthifolia-botany-medicinal-uses-phytochemistry-and-pharmacological-properties
#13
REVIEW
Alfred Maroyi
The bark, leaves, and roots of Albizia adianthifolia are highly sought after in tropical Africa as herbal medicines. Therefore, the aim of this study was to review the botany, medicinal uses, phytochemistry, and pharmacological properties of A. adianthifolia so as to provide baseline data required for evaluating the therapeutic potential of the species. Information on the botanical profile, medicinal uses, phytochemistry, and pharmacological properties of A. adianthifolia was undertaken using databases such as ScienceDirect, SciFinder, Pubmed, Google Scholar, Medline, SCOPUS, EThOS, ProQuest, OATD, and Open-thesis...
2018: TheScientificWorldJournal
https://www.readbyqxmd.com/read/30323785/prevention-of-brain-metastases
#14
REVIEW
Joseph A Bovi
The incidence of brain metastases is projected to rise because survival rates of lung cancer, breast cancer, and melanoma continue to improve (1). The brain is being identified as a sanctuary site for harboring metastases despite excellent control of extracranial disease. This is thought to occur because the drug therapies that control extracranial disease have limited central nervous system (CNS) penetration. The development of brain metastases is a devastating diagnosis affecting both quality of life (QOL) and survival...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/30323603/remitting-long-standing-major-depression-in-a-multiple-sclerosis-patient-with-several-concurrent-conditions
#15
Navzer D Sachinvala, Angeline Stergiou, Duane E Haines
In this report, we discuss the case of an multiple sclerosis (MS) patient, age 62, who learned to attain and sustain euthymia despite his ailments. He has Ehlers Danlos Syndrome (EDS), asthma, MS, urticaria, and major depression (MD). Despite thriving limitations, the patient is an accomplished scientist, who struggled for > twelve years to emerge from being confined to bed and wheel chair with MS, to walking with crutches, scuba diving, writing manuscripts, and living a positive life. Through former educators, he reacquired problem-solving habits to study the literature on his illnesses; keep records; try new therapies; and use pharmaceutical, nutritional, physical, and psychological methods to attain euthymia...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/30320718/septic-cavernous-sinus-thrombosis-associated-with-orbital-cellulitis-a-report-of-6-cases-and-review-of-literature
#16
Sara V Branson, Elysa McClintic, R Patrick Yeatts
PURPOSE: To describe risk factors, clinical parameters, treatment, and prognosis for patients with septic cavernous sinus thrombosis presenting with orbital cellulitis. METHODS: Retrospective case series of 6 patients identified with septic cavernous sinus thrombosis and orbital cellulitis confirmed by magnetic resonance imaging at a tertiary care center from January 1980 to December 2016. Medical records were reviewed for demographics, risk factors, symptoms, etiology, radiographic diagnosis, complications, treatments, and outcomes...
October 9, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/30318075/the-debate-over-neurotransmitter-interaction-in-aspartame-usage
#17
REVIEW
Arbind Kumar Choudhary, Yeong Yeh Lee
Aspartame (NutraSweet®, Equal®) is a widely used artificial sweetener, has been reported to be accountable for neurological and behavioural disturbances in people. Upon ingestion, aspartame is hydrolyzed in gut and provides its metabolite; such as essential amino acid phenylalanine (Phy) (50%), aspartic acid (40%), and methanol (10%). Altered brain neurochemical compositions [such as dopamine (DA), norepinephrine (NE), and serotonin (5-HT)] have long been a concern and being involved in observed neurophysiological symptom (such as headaches, memory loss, mood changes, as well as depression) in aspartame consumers...
October 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/30315974/bilateral-vertebral-artery-dissection-and-unilateral-carotid-artery-dissection-in-a-case-of-ehlers-danlos-syndrome-type-iv
#18
Tomotaka Ohshima, Shigeru Miyachi, Taiki Isaji, Naoki Matsuo, Reo Kawaguchi, Masakazu Takayasu
BACKGROUND: Ehlers-Danlos syndrome is a rare genetic connective tissue disorders, but the vascular type (Type IV) typically poses the greatest risk to patients. We report a case of multiple cranial artery dissection, which was successfully treated with carotid artery stenting. CASE DESCRIPTION: A 50-year-old woman presented with recurrent severe headaches caused by bilateral vertebral artery dissections that were treated conservatively at our hospital. However, she developed right cervical pain and dizziness at 3 days after admission, and a magnetic resonance angiogram revealed dissection of the right internal carotid artery...
October 10, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30314664/the-effects-of-acetazolamide-on-exercise-performance-at-sea-level-and-in-hypoxic-environments-a-review
#19
REVIEW
Alexander M Posch, Stewart Dandorf, David C Hile
Lowlanders rapidly ascending to high altitude (>2500 m) often develop acute mountain sickness (AMS). While acclimatization is the most effective method of reducing symptoms of AMS (ie, headache, fatigue, nausea, gastrointestinal distress, etc.), it may take several days to become fully acclimated. Prophylactic use of acetazolamide (AZ), a carbonic anhydrase inhibitor, has become a popular alternative to staged acclimatization because it can be a less time-consuming method of reducing symptoms of AMS. While numerous studies have shown the effectiveness of AZ in mitigating the symptoms of AMS, a review of the existing literature regarding the effects of AZ on submaximal and maximal exercise performance at sea level and at altitude has not been performed...
October 9, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/30313065/richter-s-syndrome-of-the-central-nervous-system-diagnosed-concurrently-with-chronic-lymphocytic-leukaemia-a-case-report-and-literature-review
#20
Liye Xu, Jin Cheng Song, Xiu Hua Sun, Zi Fen Gao, Li Lv, Jie Zhu
RATIONALE: Central nervous system (CNS) infiltration of Richter's syndrome (RS) is rare and only a few cases were discussed. Of these published cases, either they were accompanied with lymph node involvement or with a history of chronic lymphocytic leukemia (CLL). To our knowledge, this is the first published case of RS of the brain and meninges diagnosed concurrently with CLL in the absence of any evidence of lymphoma outside of the CNS. PATIENT CONCERNS: A 67-year-old female presented with slurred speech, headache, and left-sided hemiparesis...
October 2018: Medicine (Baltimore)
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