Hideo Kato, Yukihiro Hamada, Shotaro Takano, Shinsuke Ikeda, Yoshinori Seto, Kazuhiko Matsushita, Koji Yamada, Katsufumi Uchiyama
BACKGROUND: The use of antibiotic-loaded bone cement (ALBC) as a mean for preventing deep surgical site infections (SSI) after total joint replacement is controversial. Therefore, we have conducted a meta-analysis to evaluate the prophylactic effect of ALBC for SSI prevention in patients undergoing arthroplasty. This study was conducted to revise treatment guidelines for MRSA infections in Japan. METHODS: PubMed (Medline), Scopus, Embase, Web of Science and Cochrane library were searched for relevant articles comparing preventive effect of ALBC for patients undergoing primary total joint arthroplasty by August 2022...
March 12, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy