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Anaesthesia and tumor recurrence

Praveen Kumar Jayakumar, Jayakumar Paramasivam, Naveen Kumar Jayakumar, Gayathri Praveen Kumar, Alex Mathews Muruppel
BACKGROUND AND AIMS: An out-patient surgical procedure in the paediatric age group is a tough task for a surgeon, more so when compounded with mentally challenging conditions like cerebral palsy. Every step involved, either administration of local anaesthesia or handling sharp surgical instruments around the face or achieving haemostasis, can be a challenge, with compromise on patient safety. Neither undue restraint nor general anaesthesia is advisable, considering the magnitude of the procedure...
March 31, 2015: Laser Therapy
Fiona Desmond, Janet McCormack, Niall Mulligan, Maurice Stokes, Donal J Buggy
BACKGROUND: Live animal studies using an inoculation model of breast cancer indicate that anaesthetic drugs and techniques differentially affect cancer metastasis, inversely related to Natural Killer (NK) cell and T lymphocyte levels. Clinical histological studies demonstrate that the distribution of these immune cells and macrophages in intra-tumoral cancer tissue can predict prognosis and response to therapy. No study has evaluated whether the anaesthetic technique influences human breast cancer immune cell infiltration...
March 2015: Anticancer Research
Leena-Maija Aaltonen, Noora Rautiainen, Jaana Sellman, Kauko Saarilahti, Antti Mäkitie, Heikki Rihkanen, Jussi Laranne, Leenamaija Kleemola, Tuija Wigren, Eeva Sala, Paula Lindholm, Reidar Grenman, Heikki Joensuu
OBJECTIVE: Early laryngeal cancer is usually treated with either transoral laser surgery or radiation therapy. The quality of voice achieved with these treatments has not been compared in a randomized trial. METHODS AND MATERIALS: Male patients with carcinoma limited to 1 mobile vocal cord (T1aN0M0) were randomly assigned to receive either laser surgery (n=32) or external beam radiation therapy (n=28). Surgery consisted of tumor excision with a CO2 laser with the patient under general anaesthesia...
October 1, 2014: International Journal of Radiation Oncology, Biology, Physics
J Morris, M Callstrom
PURPOSE: To demonstrate the feasibility in treating primary and metastatic lesions to the cervical spine and paraspinal soft tissues using CT-guided cryoablation. To share techniques of avoiding/displacing critical structures and the role of intraprocedural neural monitoring including motor and sensory evoked potentials. MATERIALS AND METHODS: CT-guided cryoablation of primary and metastatic lesions involving the cervical spine performed by the authors were retrospectively reviewed...
July 2014: Journal of Neurointerventional Surgery
Vijay Ebenezer, Balakrishnan Ramalingam
BACKGROUND: The keratocystic odontogenic tumors is a benign but one of most aggressive developmental cyst with many distinguishing clinical and histologic features and high recurrence rate. In the given study, authors have studied and presented their experience of managing Keratocystic odontogenic tumour. The aim of the study was to define an appropriate treatment protocol for the management of KCOT. MATERIALS AND METHODS: Total 8 patients, whose histopathological reports confirmed Gorlin - Goltz syndrome and KCOT, with age between 10 - 50 years, were selected from cases being treated at Sree Balaji Dental College, Chennai, India...
March 2014: Journal of Clinical and Diagnostic Research: JCDR
Jun Li, Zhanjun Shi, Juehua Jing
Neurothekeomas are unusual benign soft tissue tumors of the peripheral nervous system, which commonly occur on the head, neck and upper extremities of young females in the second and third decades of life. This is the first case report of neurothekeoma developing simultaneously in the thoracic and lumbar area in a 51-year-old male. The two tumors were completely excised along the capsule under local anaesthesia and the incisions were closed in layers following adequate hemostasis. Histopathologically, the examination of the microscopic slides from the thoracic and lumbar masses revealed the presence of spindle and similar epithelioid cells arranged in fascicles, often in a geographical pattern, in a background of myxoid stroma...
January 2014: Molecular and Clinical Oncology
Sumit Gupta, C Vasu Reddy, Shyam Thapa Chettri, Smriti Karki
Thyroid surgery evolution is important with a lots of hurdles faced by many surgeons to reach the present stage. The complications from the olden days reduced with improvement in understanding the disease process, development of antibiotics, anaesthesia and now restricted mainly to hypoparathyroidism and recurrent laryngeal nerve injuries. A retrospective analysis of thyroid surgeries performed at BP Koirala Institute of Health Sciences centre from 2007 to 2011 Clinicopathological features and complications were analyzed...
April 2013: Indian Journal of Otolaryngology and Head and Neck Surgery
Shinji Yamaguchi, Madoka Inui, Takashi Takeoka, Kenya Okumura, Toshiro Tagawa
Calcifying epithelioma, a benign tumor derived from the hair apparatus and consisted of hair matrix cells, is relatively prevalent in females. We report a case of right preauricular calcifying epithelioma that was incidentally detected at the examination of multiple facial fractures and became an old lesion without symptoms for 40 years. The patient who was a 42-year-old male visited our department for the first time in October 2011 with a chief complaint of multiple facial fractures. Radiographic imaging demonstrated fracture lines at the anterior and posterior walls of the left maxillary sinus and zygomatic arch and revealed a mass at a right preauricular area...
2013: Case Reports in Dentistry
Patrick Y Wuethrich, George N Thalmann, Urs E Studer, Fiona C Burkhard
BACKGROUND: A beneficial effect of regional anesthesia on cancer related outcome in various solid tumors has been proposed. The data on prostate cancer is conflicting and reports on long-term cancer specific survival are lacking. METHODS: In a retrospective, single-center study, outcomes of 148 consecutive patients with locally advanced prostate cancer pT3/4 who underwent retropubic radical prostatectomy (RRP) with general anesthesia combined with intra- and postoperative epidural analgesia (n=67) or with postoperative ketorolac-morphine analgesia (n=81) were reviewed...
2013: PloS One
Hua Fan, Han-zhong Li, Yu-shi Zhang, Xue-bin Zhang, Bing-bing Shi
To investigate the clinicopathological characteristics of metanephric adenoma (MA), we analyzed the clinical and pathological data of metanephric adenoma. A 39-year old woman with asymptomatic right kidney tumor for 4 years was admitted to the hospital. A tumor with the largest diameter of 28 mm in the right kidney was homogeneously enhanced on CT. The tumor was distinctly increased as compared with 4 years before. The diagnosis was right kidney tumor. Nephron-sparing surgery was given after general anaesthesia...
August 18, 2013: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Dariusz Kaczmarczyk, Dorota Jesionek-Kupnicka, Marcin Kubiak, Alina Morawiec-Sztandera
Liposarcoma is the most common soft tissue malignant tumor. It mostly arises in the subcutaneous tissue of shoulders, limbs and neck, and retroperitoneal space, but head occurrence is very rare. Atypical lipomatous tumor (ALT) is a well-differentiated liposarcoma (WDLPS) and constitutes 40-45% of all liposarcoma cases. A case of 57-year-old woman with a tumor of the left cheek, causing a discreet face asymmetry is presented. The tumor was soft and caused no tenderness. The patient reported no previous injury of the region...
July 2013: Otolaryngologia Polska. the Polish Otolaryngology
Ajit Mahale, Dhananjaya K V N, Muralidhar Pai, Vinaya Poornima, Kausalya Kumari Sahu
Giant cell tumours of the clivus are rare. These tumours present in the second and third decades of life and they are slightly more frequent in women than in men. We are presenting a case of a 20 years young patient who came with the complaints of headache, retro-orbital pain and recurrent transient bleeding from the nose since two and half months. MRI of the brain with contrast was done and its features were suggestive of a Giant cell tumour of the clivus. A transnasal endoscopic biopsy was done under general anaesthesia and the histopathology report suggested that the features were of a giant cell tumour...
June 2013: Journal of Clinical and Diagnostic Research: JCDR
Dheeraj Kumar Gupta, Vishwajeet Singh, Rahul Janak Sinha, Vijay Kumar, Deepak Sharanappa Nagathan, Satya Narayan Sankhwar
A 22-year-old young woman presented with dysuria and lower urinary tract symptoms that had persisted for 6 months. She was diagnosed with a tumor near the bladder neck. Transurethral resection was done under anaesthesia. The histopathological examination with immunohistochemical staining showed the tumor to be a low-grade leiomyosarcoma. Adjuvant chemoradiation was given, and the patient has been doing well for 12 months of follow-up. Nonurothelial tumors of the bladder are rare and consensus is lacking regarding their definitive treatment...
June 2013: Korean Journal of Urology
Bin Fang, Chunzhi Yi, Hua Zhang, Qingwen Zhang, Yong Li, Qiushi Wei, Wei He, Zuoqing Zeng
OBJECTIVE: To investigate the clinical application and early results of combined epiphyseal preservation. METHODS: Between March 2010 and March 2011, and autograft bone transfer for limb salvage in children with osteosarcoma. 3 children with osteosarcoma were treated with epiphyseal preservation and autograft bone transfer. There were 1 boy and 2 girls with the age of 10-14 years. The disease duration was 2 weeks to 3 months. The tumors were rated as type II according to San-Julian radiological classification and as type IIB according to Enneking surgical classification...
January 2013: Chinese Journal of Reparative and Reconstructive Surgery
Wei-wei Liu, Jin-yong Lin, Xiao-hong Yu
OBJECTIVE: To explore the clinical and pathological features of conjunctival myxoma and angiomyxoma. METHODS: It was a retrospective case series study. The clinical and pathological features of 3 cases of conjunctival myxoma and 2 cases of conjunctival angiomyxoma were analyzed. These cases were treated from January 2005 to December 2010 at Tianjin Eye Hospital. Routine pathological examinations and immunohistochemical staining were performed, including staining for Vimentin, S-100, SMA and CD34...
November 2012: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
S Goswami, I N Kundu, P K Majumdar, A K Saha, B Haider
A nine month old male child presented with a swelling protruding from the right nasal cavity for two months. Other symptoms were mild breathlessness during suckling and blood stained nasal discharge. CT Scan sshowed a mass arising from the lasteral wall of the right nasal cavity with mild erosion of the adjacent bones. The tumor was excised with wide margin through a lateral rhinotomy approach under general anaesthesia. In histopathological examination it was found to be a low grade neurofibrosarcoma. The child recovered well and is free from any recurrence till the time of reporting...
April 2001: Indian Journal of Otolaryngology and Head and Neck Surgery
Vaclav Simanek, Jiri Klecka, Vladislav Treska, Kristyna Ohlidalova, Hynek Mirka
BACKGROUND: Radiofrequency thermal ablation (RFA) is a minimally invasive, image guided technique for destroying tumour cells without damage to adjacent healthy tissue. It is used for partial or complete ablation of non resectable lung cancers and cancers of metastases to lung, providing an effective, relatively safe option for patients ineligible for surgery. We describe our experience with it. METHODS: In 2005 and 2006, we performed radiofrequency ablation of 7 lung lesions in 6 patients...
September 2014: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
Fabio Pagella, Francesco Chu, Alessandro Pusateri, Elina Matti
Pleomorphic adenoma is the most common benign tumor of the parotid glands. Rarely it may arise from minor salivary glands of the upper aerodigestive tract. A 57-year-old woman was admitted at our institution presenting with nasal obstruction. Endoscopic evaluation revealed a pedicled mass in the rhinopharynx. After radiological examination, we opted for a transnasal endoscopic-assisted excision of the mass under general anaesthesia. Histological evaluation deponed for pleomorphic adenoma with clear surgical margins...
2012: Case Reports in Medicine
Piero Campolmi, Paolo Bonan, Giovanni Cannarozzo, Andrea Bassi, Nicola Bruscino, Meena Arunachalam, Michela Troiano, Torello Lotti, Silvia Moretti
The CO(2) laser has been used extensively in dermatological surgery over the past 30 years and is now recognised as the gold standard for soft tissue vaporization. Considering that the continuous wave CO(2) laser delivery system and the newer "superpulsed" and scanned CO(2) systems have progressively changed our practice and patient satisfaction, a long range documentation can be useful. Our experience has demonstrated that the use of CO(2) laser involves a reduced healing time, an infrequent need for anaesthesia, reduced thermal damage, less bleeding, less inflammation, the possibility of intra-operative histologic and/or cytologic examination, and easy access to anatomically difficult areas...
2012: TheScientificWorldJournal
H Beloeil, K Nouette-Gaulain
Surgical treatment of cancer is usually necessary but it can paradoxically aggravate the patient outcome by increasing the risk of recurrence. Many perioperative factors have been shown to contribute to the dissemination of the tumor: surgery itself, stress, inflammation, pain, anaesthetic drugs, blood transfusion, etc. The type of anaesthesia chosen in the cancer patient could then be crucial and influence the evolution of the disease. Experimental, preclinical and retrospective studies have suggested that a regional anesthesia associated or not with a general anesthesia for carcinologic surgery might reduce the risk of cancer recurrence...
June 2012: Annales Françaises D'anesthèsie et de Rèanimation
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