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https://www.readbyqxmd.com/read/27913892/early-harvest-effects-on-hydrophilic-phenolic-components-of-extra-virgin-olive-oils-cvs-ayval%C3%A4-k-memecik-and-topaka%C3%A5-%C3%A4
#1
Fatma Yıldırım, Adnan Nurhan Yıldırım, Gülcan Özkan, Bekir Şan, Mehmet Polat, Hatice Aşık, Yaşar Karakurt, Sezai Ercişli
The study was conducted to determine the effects of cultivar, harvest period, and their interaction on the hydrophilic phenolic components extra virgin olive oils of the cultivars 'Ayvalık,' 'Memecik,' and 'Topakaşı.' Olives were collected at three different harvesting periods: (1) early harvest period-1 (Beginning of spotting), (2) early harvest period-2 (End of spotting), and (3) optimum harvest period. Oils were extracted using the Abencor system. HPLC (High-performance liquid chromatograph) technique was used to quantify the phenolic compounds including tyrosol (p-HPEA), hydroxytyrosol (3,4-DHPEA), luteolin, rutin, quercetin, catechin, sinapinic acid, p-coumaric acid, cinnamic acid, vanillin, vanillic acid, ferulic acid, and gallic acid...
December 2, 2016: Biochemical Genetics
https://www.readbyqxmd.com/read/27907867/adsorption-characteristics-of-adsorbent-resins-and-antioxidant-capacity-for-enrichment-of-phenolics-from-two-phase-olive-waste
#2
Zhihong Wang, Chengzhang Wang, Jiaojiao Yuan, Changwei Zhang
In this study, the adsorption properties of nine resins including polyamide resin (30-60), polyamide resin (60-100) AB-8, S-8, D-101, NKA-9, NKA-II, XDA-1 and XDA-4 for enrichment phenolics of the olive waste were investigated. XDA-1 and NKA-II were chosen for further study due to their outstanding adsorption and desorption capacity. XDA-1 and NKA-II had similar adsorption and desorption behaviors for phenolics of olive waste. The adsorption mechanism could be better explained by pseudo second-order kinetics model and Freundlich isotherm model, and the adsorption processes were spontaneously and exothermic...
November 24, 2016: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/27810738/hydroxytyrosol-inhibits-hydrogen-peroxide-induced-apoptotic-signaling-via-labile-iron-chelation
#3
Natalia Kitsati, Michalis D Mantzaris, Dimitrios Galaris
Although it is known that Mediterranean diet plays an important role in maintaining human health, the underlying molecular mechanisms remain largely unknown. The aim of this investigation was to elucidate the potential role of ortho-dihydroxy group containing natural compounds in H2O2-induced DNA damage and apoptosis. For this purpose, the main phenolic alcohols of olive oil, namely hydroxytyrosol and tyrosol, were examined for their ability to protect cultured cells under conditions of oxidative stress. A strong correlation was observed between the ability of hydroxytyrosol to mitigate intracellular labile iron level and the protection offered against H2O2-induced DNA damage and apoptosis...
October 15, 2016: Redox Biology
https://www.readbyqxmd.com/read/27803730/quick-assessment-of-the-economic-value-of-olive-mill-waste-water
#4
Riccardo Delisi, Filippo Saiano, Mario Pagliaro, Rosaria Ciriminna
BACKGROUND: Olive biophenols are emerging as a valued class of natural products finding practical application in the food, pharmaceutical, beverage, cosmetic and nutraceutical industries due to their powerful biological activity which includes antioxidant and antimicrobial properties. Olive mill waste water (OMWW), a by-product in olive oil manufacturing, is rich in biophenols such as hydroxytyrosol and tyrosol. The amount of biophenols depends on the cultivar, the geographical area of cultivation, and the seasonal conditions...
2016: Chemistry Central Journal
https://www.readbyqxmd.com/read/27792767/association-between-polyphenol-intake-and-hypertension-in-adults-and-older-adults-a-population-based-study-in-brazil
#5
Andreia Machado Miranda, Josiane Steluti, Regina Mara Fisberg, Dirce Maria Marchioni
BACKGROUND/OBJECTIVE: Hypertension is an important risk factor for cardiovascular disease, and diet has been identified as a modifiable factor for preventing and controlling hypertension. Besides, epidemiological studies have suggested an inverse association between polyphenol intake and cardiovascular diseases. The aim of this study was to evaluate the association between the intake of polyphenols and hypertension in a general population of Sao Paulo. METHODS: Data came from the 'Health Survey of Sao Paulo (ISA-Capital)' among 550 adults and older adults in Sao Paulo, Brazil...
2016: PloS One
https://www.readbyqxmd.com/read/27792334/phenolic-compounds-and-sesquiterpene-lactones-profile-in-leaves-of-nineteen-artichoke-cultivars
#6
Youssef Rouphael, Jamila Bernardi, Mariateresa Cardarelli, Letizia Bernardo, David Kane, Giuseppe Colla, Luigi Lucini
Leaves of globe artichoke are food industry by-products gaining interest due to their therapeutic and nutraceutical potential. The total phenolics, flavonoids and flavonols content, as well as radical scavenging capacity and reducing antioxidant power were determined in leaves of nineteen artichoke cultivars. An untargeted analysis based on high-resolution mass spectrometry was then carried out to profile phenolic compounds and sesquiterpene lactones (STLs). The phenolic profile of leaf extracts from different cultivars was widely diverse and included flavonoids, hydroxycinnamic acids, tyrosols and lignans...
October 28, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27790915/exploring-the-colonic-metabolism-of-grape-and-strawberry-anthocyanins-and-their-in-vitro-apoptotic-effects-in-ht-29-colon-cancer-cells
#7
Maria-Carmen López de Las Hazas, Juana I Mosele, Alba Macià, Iziar A Ludwig, Maria-Jose' Motilva
Beneficial properties attributed to the intake of fruit and red wine have been associated with the presence of significant amounts of anthocyanins. However, their low absorption and consequent accumulation in the gut have generated the suspicion that colonic metabolites of anthocyanins are probably involved in their protective effects. Grape pomace and strawberries extracts, rich in malvidin- and pelargonidin-glucoside, respectively, were fermented in-vitro using human feces as microbial inoculum. After 8 h of anaerobic incubation, the anthocyanins were almost completely degraded while their microbial metabolites concentration was highest at 24 h...
October 28, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27713969/effect-of-bactrocera-oleae-on-phenolic-compounds-and-antioxidant-and-antibacterial-activities-of-two-algerian-olive-cultivars
#8
Lynda Medjkouh, Abderezak Tamendjari, Rita C Alves, Mariana Araújo, M Beatriz P P Oliveira
Bactrocera oleae, an olive fruit fly, is a major olive pest in Algeria. In this study, olives of two Algerian cultivars (Limli and Rougette de Métidja) with different degrees of infestation by the Bactrocera oleae fly (0%, not attacked; 100%, all attacked; and real %) were analysed. The influence of this pest on individual phenolic compounds (HPLC-DAD-FLD) and antioxidant profiles was ascertained. The antibacterial activity against 8 human enteropathogenic bacteria was also assessed. The results show that Rougette de Métidja, the cultivar with higher drupe size, was attacked to a greater degree than Limli, and the B...
October 12, 2016: Food & Function
https://www.readbyqxmd.com/read/27713961/anti-cancer-properties-of-olive-oil-secoiridoid-phenols-a-systematic-review-of-in-vivo-studies
#9
R Fabiani
Epidemiological studies suggest that olive oil intake is associated to a reduced risk of cancer. Recently, the chemopreventive activity of olive oil has been attributed to its unique phenolic compounds represented by phenolic alcohols, hydroxytyrosol (3,4-dihydroxyphenylethanol: 3,4-DHPEA) and tyrosol (p-hydroxyphenylethanol: p-HPEA), and their secoiridoid derivatives 3,4-DHPEA-EA (oleuropein aglycon), p-HPEA-EA (ligstroside aglycon), 3,4-DHPEA-EDA, p-HPEA-EDA (oleocanthal), and oleuropein. Several studies have demonstrated that these compounds are able to inhibit proliferation and induce apoptosis in different tumor cell lines...
October 12, 2016: Food & Function
https://www.readbyqxmd.com/read/27664690/cyp2d6-and-cyp2a6-biotransform-dietary-tyrosol-into-hydroxytyrosol
#10
Jose Rodríguez-Morató, Patricia Robledo, Julie-Anne Tanner, Anna Boronat, Clara Pérez-Mañá, C-Y Oliver Chen, Rachel F Tyndale, Rafael de la Torre
The dietary phenol tyrosol has been reported to be endogenously transformed into hydroxytyrosol, a potent antioxidant with multiple health benefits. In this work, we evaluated whether tyrosine hydroxylase (TH) and cytochrome P450s (CYPs) catalyzed this process. To assess TH involvement, Wistar rats were treated with α-methyl-L-tyrosine and tyrosol. Tyrosol was converted into hydroxytyrosol whilst α-methyl-L-tyrosine did not inhibit the biotransformation. The role of CYP was assessed in human liver microsomes (HLM) and tyrosol-to-hydroxytyrosol conversion was observed...
February 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27627637/in-vitro-inhibitory-effects-of-plant-derived-by-products-against-cryptosporidium-parvum
#11
Klaus Teichmann, Maxime Kuliberda, Gerd Schatzmayr, Thomas Pacher, Karin Zitterl-Eglseer, Anja Joachim, Franz Hadacek
Disposal of organic plant wastes and by-products from the food or pharmaceutical industries usually involves high costs. In the present study, 42 samples derived from such by-products were screened in vitro against Cryptosporidium parvum, a protozoan parasite that may contaminate drinking water and cause diarrhoea. The novel bioassay was previously established in the microtitre plate format. Human ileocaecal adenocarcinoma (HCT-8) cell cultures were seeded with C. parvum oocysts and parasite development was monitored by an indirect fluorescent antibody technique (IFAT) and microscopic assessment for clusters of secondary infection (CSI)...
2016: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/27572116/in-vitro-inhibition-of-cytochrome-p-450-activities-and-quantification-of-constituents-in-a-selection-of-commercial-rhodiola-rosea-products
#12
Ole Kristian Thu, Odd Georg Nilsen, Bent Hellum
CONTEXT: Rhodiola rosea L. (Crassulaceae) products are popular natural remedies with a worldwide distribution. Recent studies have revealed potent CYP inhibition by R. rosea extracts both in vitro and in vivo, but information on in vitro CYP inhibition by commercial products are lacking. Variations in commercial R. rosea product quality have also been published. OBJECTIVE: This study evaluates the variation of in vitro CYP inhibition potential and product quality of six commercially available R...
August 29, 2016: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27552663/phytochemical-profiling-as-a-solution-to-palliate-disinfectant-limitations
#13
J Malheiro, I Gomes, A Borges, M M S M Bastos, J-Y Maillard, F Borges, M Simões
The indiscriminate use of biocides for general disinfection has contributed to the increased incidence of antimicrobial tolerant microorganisms. This study aims to assess the potential of seven phytochemicals (tyrosol, caffeic acid, ferulic acid, cinnamaldehyde, coumaric acid, cinnamic acid and eugenol) in the control of planktonic and sessile cells of Staphylococcus aureus and Escherichia coli. Cinnamaldehyde and eugenol showed antimicrobial properties, minimum inhibitory concentrations of 3-5 and 5-12 mM and minimum bactericidal concentrations of 10-12 and 10-14 mM against S...
October 2016: Biofouling
https://www.readbyqxmd.com/read/27520529/terpinen-4-ol-tyrosol-and-%C3%AE-lapachone-as-potential-antifungals-against-dimorphic-fungi
#14
Raimunda Sâmia Nogueira Brilhante, Érica Pacheco Caetano, Rita Amanda Chaves de Lima, Francisca Jakelyne de Farias Marques, Débora de Souza Collares Maia Castelo-Branco, Charlline Vládia Silva de Melo, Glaucia Morgana de Melo Guedes, Jonathas Sales de Oliveira, Zoilo Pires de Camargo, José Luciano Bezerra Moreira, André Jalles Monteiro, Tereza de Jesus Pinheiro Gomes Bandeira, Rossana de Aguiar Cordeiro, Marcos Fábio Gadelha Rocha, José Júlio Costa Sidrim
This study aimed to evaluate the in vitro antifungal activity of terpinen-4-ol, tyrosol, and β-lapachone against strains of Coccidioides posadasii in filamentous phase (n=22) and Histoplasma capsulatum in both filamentous (n=40) and yeast phases (n=13), using the broth dilution methods as described by the Clinical and Laboratory Standards Institute, to determine the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of these compounds. The mechanisms of action of these compounds were also investigated by analyzing their effect on cell membrane permeability and ergosterol synthesis...
October 2016: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/27507587/quorum-sensing-in-yeast-and-its-potential-in-wine-making
#15
REVIEW
Martina Avbelj, Jure Zupan, Peter Raspor
This mini-review synthesises the present knowledge of microbial quorum-sensing, with a specific focus on quorum-sensing in yeast, and especially in wine yeast. In vine and wine ecosystems, yeast co-interact with a large variety of microorganisms, thereby affecting the fermentation process and, consequently, the flavour of the wine. The precise connections between microbial interactions and quorum-sensing remain unclear, but we describe here how and when some species start to produce quorum-sensing molecules to synchronously adapt their collective behaviour to new conditions...
September 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27380032/antioxidant-behavior-of-olive-phenolics-in-oil-in-water-emulsions
#16
Vito Michele Paradiso, Carla Di Mattia, Mariagrazia Giarnetti, Marco Chiarini, Lucia Andrich, Francesco Caponio
The effect of the surrounding molecular environment (β-lactoglobulin as an emulsion stabilizer and maltodextrin as a viscosity modifier) on the antioxidant activity of three olive oil phenolic compounds (PCs) in olive oil-in-water emulsions was investigated. Oxidation potential, phenolic partitioning, and radical quenching capacity were assessed in solution and in emulsion for oleuropein, hydroxytyrosol, and tyrosol; the influence of β-lactoglobulin and maltodextrin concentration was also evaluated. Finally, the observed properties were related to the oxidative stability of the emulsions containing the PCs to explain their behavior...
July 27, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27375250/survival-of-foodborne-pathogens-in-natural-cracked-olive-brines
#17
Eduardo Medina, Verónica Romero-Gil, Antonio Garrido-Fernández, Francisco Noé Arroyo-López
This work reports the survival (challenge tests) of foodborne pathogen species (Escherichia coli, Staphylococcus aureus, Listeria monocytogenes, and Salmonella enterica) in Aloreña de Málaga table olive brines. The inhibitions were fit using a log-linear model with tail implemented in GInaFIT excel software. The olive brine had a considerable inhibitory effect on the pathogens. The residual (final) populations (Fp) after 24 h was below detection limit (<1.30 log10 cfu/mL) for all species assayed. The maximum death rate (kmax) was 9...
October 2016: Food Microbiology
https://www.readbyqxmd.com/read/27355793/biophenols-from-table-olive-cv-bella-di-cerignola-chemical-characterization-bioaccessibility-and-intestinal-absorption
#18
Isabella D'Antuono, Antonella Garbetta, Biancamaria Ciasca, Vito Linsalata, Fiorenza Minervini, Veronica M T Lattanzio, Antonio F Logrieco, Angela Cardinali
In this study, the naturally debittered table olives cv Bella di Cerignola were studied in order to (i) characterize their phenolic composition; (ii) evaluate the polyphenols bioaccessibility; (iii) assess their absorption and transport, across Caco2/TC7. LC-MS/MS analysis has confirmed the presence of hydroxytyrosol acetate, caffeoyl-6'-secologanoside, and comselogoside. In vitro bioaccessibility ranged from 7% of luteolin to 100% of tyrosol, highlighting the flavonoids sensitivity to the digestive conditions...
July 20, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27350009/relative-potency-of-tyrosol-in-the-treatment-of-endotoxin-induced-uveitis-in-rats
#19
Kazuaki Sato, Yuko Mihara, Kazutaka Kanai, Yohei Yamashita, Yuya Kimura, Naoyuki Itoh
Tyrosol (Tyr) is a natural phenolic antioxidant with diverse biological activities. We compared the anti-inflammatory effects of intravenously administered Tyr versus prednisolone (PSL) in an endotoxin-induced uveitis (EIU) rat model. Intravenous administration of 100 mg/kg Tyr was performed 2 hr before, simultaneously and 2 hr after lipopolysaccharide (LPS) injection. Tyr treatment was associated with decreased inflammatory cell number, protein concentration, tumor necrosis factor (TNF)-α, PGE2 and NO levels in AqH and improvements in histopathologic evidence of EIU in ocular tissue at 24 hr after LPS injection...
June 26, 2016: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/27337069/synthesis-and-antioxidant-activity-of-hydroxytyrosol-alkyl-carbonate-derivatives
#20
Ignacio Fernandez-Pastor, Antonia Fernandez-Hernandez, Francisco Rivas, Antonio Martinez, Andres Garcia-Granados, Andres Parra
Three procedures have been investigated for the isolation of tyrosol (1) and hydroxytyrosol (2) from a phenolic extract obtained from the solid residue of olive milling. These three methods, which facilitated the recovery of these phenols, were chemical or enzymatic acetylation, benzylation, and carbomethoxylation, and subsequent carbonylation or acetonation reactions. Several new lipophilic alkyl-carbonate derivatives of hydroxytyrosol have been synthesized, coupling the primary hydroxy group of this phenol, through a carbonate linker, using alcohols with different chain lengths...
July 22, 2016: Journal of Natural Products
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