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Raphael Schuster, Sophia Sigl, Thomas Berger, Anton-Rupert Laireiter
BACKGROUND: Blended group therapy combines group sessions with Web- and mobile-based treatment modules. Consequently, blended group therapy widens the choice within blended interventions at reasonable costs. This is the first qualitative study on blended group therapy. OBJECTIVE: The objective of this study was to investigate the patient-centered feasibility of blended group therapy for major depression, with special emphasis on the fit and dynamic interplay between face-to-face and internet-based elements...
July 11, 2018: JMIR Mental Health
J L de Geus, L M Wambier, T F Boing, A D Loguercio, A Reis
OBJECTIVE: To perform a systematic review to answer the following research question: Is at-home bleaching in adults with more concentrated carbamide peroxide (CP) gels as effective and safe as bleaching performed with 10% carbamide peroxide gels? METHODS AND MATERIALS: A comprehensive search was carried out in the MEDLINE via PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library and SIGLE, without restrictions. IADR abstracts (1990 to 2016) and unpublished and ongoing trial registries, dissertations and theses (ProQuest Dissertations and Periodicos Capes Theses Databases) were also searched...
July 2018: Operative Dentistry
Christian Rubbert, Kaustubh R Patil, Kerim Beseoglu, Christian Mathys, Rebecca May, Marius G Kaschner, Benjamin Sigl, Nikolas A Teichert, Johannes Boos, Bernd Turowski, Julian Caspers
OBJECTIVES: The pathogenesis leading to poor functional outcome after aneurysmal subarachnoid haemorrhage (aSAH) is multifactorial and not fully understood. We evaluated a machine learning approach based on easily determinable clinical and CT perfusion (CTP) features in the course of patient admission to predict the functional outcome 6 months after ictus. METHODS: Out of 630 consecutive subarachnoid haemorrhage patients (2008-2015), 147 (mean age 54.3, 66.7% women) were retrospectively included (Inclusion: aSAH, admission within 24 h of ictus, CTP within 24 h of admission, documented modified Rankin scale (mRS) grades after 6 months...
June 12, 2018: European Radiology
Wentian Sun, Kai Xia, Xinqi Huang, Xiao Cen, Qing Liu, Jun Liu
BACKGROUND: To investigate the feasibility, safety and stability of current interventions for moving teeth through the maxillary sinus (MTTMS) by performing a systematic review of the literature. METHODS: The electronic databases PubMed, Embase, CENTRAL, Web of Science, CBM, CNKI and SIGLE were searched without a language restriction. The primary outcomes were parameters related to orthodontic treatment, including orthodontic protocols, magnitude of forces, type of tooth movement, duration and rate of tooth movement, and remolding of alveolar bone and the maxillary sinus floor...
May 23, 2018: BMC Oral Health
Leah T Sigle, Julián F Hillyer
The primary pump of the circulatory system of insects is a dorsal vessel that traverses the length of the insect. The anterior portion, located in the head, neck and thorax, is the aorta, and the posterior portion, located in the abdomen, is the heart. Here, we characterize the structure and function of the aorta and conical chamber of the mosquito, Anopheles gambiae The aorta begins in the head with an excurrent opening located above the dorsal pharyngeal plate and ends at the thoraco-abdominal junction where it joins the conical chamber of the heart...
June 22, 2018: Journal of Experimental Biology
Olavo B de Oliveira-Neto, Fabiano Timbo Barbosa, Celio Fernando de Sousa-Rodrigues, Fernando Jose Camello de Lima
STATEMENT OF PROBLEM: Although dental implant treatment has a high success rate, patient-related factors may cause implant failure. In this context, smoking is associated with adverse effects on implant osseointegration. In spite of systematic reviews addressing this topic, the risk of bias in these reviews must be assessed to inform readers whether the studies were conducted with methodological rigor and whether their recommendations are viable in daily clinical practice. PURPOSE: The purpose of this umbrella systematic review was to assess the risk of bias of systematic reviews regarding dental implant placement in smokers...
April 30, 2018: Journal of Prosthetic Dentistry
F Baiutti, G Gregori, Y E Suyolcu, Y Wang, G Cristiani, W Sigle, P A van Aken, G Logvenov, J Maier
The utilization of interface effects in epitaxial systems at the nanoscale has emerged as a very powerful approach for engineering functional properties of oxides. Here we present a novel structure fabricated by a state-of-the-art oxide molecular beam epitaxy method and consisting of lanthanum cuprate and strontium (Sr)-doped lanthanum nickelate, in which interfacial high-temperature superconductivity (Tc up to 40 K) occurs at the contact between the two phases. In such a system, we are able to tune the superconducting properties simply by changing the structural parameters...
May 10, 2018: Nanoscale
Ana Cristina Corrêa Figueira, António Cortinhas, Jorge Pinto Soares, José Carlos Leitão, Rita Pinho Ferreira, Jose Alberto Duarte
The use of preclinical models to investigate antitumor effects of exercise on breast tumor (BT) development and progression are critical. However, published results have not been quantitatively summarized or examined for potential exercise-moderating variables. We conducted this review to summarize and quantify the effect-size of exercise on BT outcomes in preclinical studies. A literature search was performed in MEDLINE, PubMed, Web of Science and System for Information on Grey Literature in Europe (SIGLE) databases...
May 2018: International Journal of Sports Medicine
Zhen Li, Fei Huang, Xin Feng, Aihua Yan, Haiming Dong, Miao Hu, Qi Li
A two-phase-coexistence technique offers intriguing variables to maneuver novel and enhanced functionality in a single-component material. Most importantly, new band alignment and perfect interfaces between two phases can strongly affect local photoelectronic properties. However, previous efforts to achieve two-phase coexistence were mainly restricted to specific systems and methods. Here we demonstrate a phase-transition route to acquire two-phase-coexistence niobium oxyfluoride (Nb3 O7 F) nanocrystals for the first time...
June 1, 2018: Nanotechnology
Joanna Marczak, Wendy Sigle, Ernestina Coast
In research and policy discourse, conceptualizations of fertility decision-making often assume that people only consider circumstances within national borders. In an integrated Europe, citizens may know about and compare conditions across countries. Such comparisons may influence the way people think about and respond to childrearing costs. To explore this possibility and its implications, we present evidence from 44 in-depth interviews with Polish parents in the United Kingdom and Poland. Explanations of childbearing decisions involved comparisons of policy packages and living standards across countries...
July 2018: Population Studies
L T Sigle, J F Hillyer
Haemocytes respond to infection by phagocytosing pathogens, producing the enzymes that drive the phenoloxidase-based melanization cascade, secreting lytic factors, and producing other humoral proteins. A subset of haemocytes, called periostial haemocytes, aggregate on the surface of the heart of mosquitoes and kill pathogens in areas of high haemolymph flow. Periostial haemocytes are always present, but an infection induces the recruitment of additional haemocytes to these regions. Here, we tested whether members of the Nimrod gene family are involved in the periostial immune response of the African malaria mosquito, Anopheles gambiae...
March 9, 2018: Insect Molecular Biology
J-P Sigle, B Mihm, R Suna, M Bargetzi
BACKGROUND: Daratumumab (DARA) causes non-specific results in indirect agglutination testing (IAT). Dithiothreitol (DTT) treatment of panel red blood cells (RBCs) abolishes DARA interference. The objective of our study was to extend stability of DTT-treated panel RBCs to 28 days through application of a commercially available panel RBC stabilizer. MATERIALS AND METHODS: Serological antigen typing and IAT using DARA sera and DARA plasma spiked with weakly reacting alloantibodies was performed up to 28 days after DTT treatment and stabilization...
May 2018: Vox Sanguinis
N Vats, S Rauschenbach, W Sigle, S Sen, S Abb, A Portz, M Dürr, M Burghard, P A van Aken, K Kern
Aberration-corrected high-resolution transmission electron microscopy (AC-HRTEM) has enabled atomically resolved imaging of molecules adsorbed on low-dimensional materials like carbon nanotubes, graphene oxide and few-layer-graphene. However, conventional methods for depositing molecules onto such supports lack selectivity and specificity. Here, we describe the chemically selective preparation and deposition of molecules-like polyoxometalate (POM) anions [PW12 O40 ]3- using electrospray ion-beam deposition (ES-IBD) along with high-resolution TEM imaging...
March 8, 2018: Nanoscale
Yi Wang, Y Eren Suyolcu, Ute Salzberger, Kersten Hahn, Vesna Srot, Wilfried Sigle, Peter A van Aken
Specimen and stage drift as well as scan distortions can lead to a mismatch between true and desired electron probe positions in scanning transmission electron microscopy (STEM) which can result in both linear and nonlinear distortions in the subsequent experimental images. This problem is intensified in STEM spectrum and diffraction imaging techniques owing to the extended dwell times (pixel exposure time) as compared to conventional STEM imaging. As a consequence, these image distortions become more severe in STEM spectrum/diffraction imaging...
March 1, 2018: Microscopy
S Rajasekharan, L C Martens, R G E C Cauwels, R P Anthonappa, R M H Verbeeck
INTRODUCTION: Biodentine™ has frequently been acknowledged in the literature as a promising material and serves as an important representative of tricalcium silicate based cements used in dentistry. AIM: To provide an update on the physical and biological properties of Biodentine™ and to compare these properties with those of other tricalcium silicate cements namely, different variants of mineral trioxide aggregate (MTA) such as ProRoot MTA, MTA Angelus, Micro Mega MTA (MM-MTA), Retro MTA, Ortho MTA, MTA Plus, GCMTA, MTA HP and calcium enriched mixture (CEM), Endosequence and Bioaggregate™...
February 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
Bianca Medeiros Maran, Adrieli Burey, Thalita de Paris Matos, Alessandro D Loguercio, Alessandra Reis
OBJECTIVE: A systematic review and meta-analysis were performed to answer the following research question: Does light-activated in-office vital bleaching have a greater whitening efficacy and higher tooth sensitivity (TS) in comparison with in-office vital bleaching without light when used in adults? DATA AND SOURCE: Only randomized clinical trials (RCTs) involving adults who had in-office bleaching with and without light activation were included. Controlled vocabulary and keywords were used in a comprehensive search for titles and abstracts in PubMed, and this search was adapted for Scopus, Web of Science, LILACS, BBO, Cochrane Library, and SIGLE without restrictions in May 2016 and was updated in August 2017...
March 2018: Journal of Dentistry
Bianca Marques Santiago, Leopoldina Almeida, Yuri Wanderley Cavalcanti, Marcela Baraúna Magno, Lucianne Cople Maia
The age estimation is a complex procedure required in the daily practice of legal medicine. The maturity of third molars stands out by the age of 18 because these teeth are still in development. This systematic review aimed to assess the accuracy of the third molar maturity index (I 3M ), proposed by Cameriere et al. (2008), in discriminating whether an individual is under or over 18 years. Seven electronic databases were screened: PubMed, Scopus, ISI Web of Science, Cochrane Library, LILACS, SIGLE, and CAPES...
July 2018: International Journal of Legal Medicine
Shuan Rao, Shane J F Cronin, Verena Sigl, Josef M Penninger
The tumor necrosis factor (TNF) receptor RANK (TNFRSF11A) and its ligand RANKL (TNFSF11) regulate osteoclast development and bone metabolism. They also control stem cell expansion and proliferation of mammary epithelial cells via the sex hormone progesterone. As such, RANKL and RANK have been implicated in the onset of hormone-induced breast cancer. Recently, RANK/RANKL were identified as crucial regulators for BRCA1 mutation-driven breast cancer. Current prevention strategies for BRCA1 mutation carriers are associated with wide-ranging risks; therefore, the search for alternative, non-invasive strategies is of paramount importance...
March 2018: Trends in Cell Biology
Klaus F Wagenbauer, Christian Sigl, Hendrik Dietz
Natural biomolecular assemblies such as molecular motors, enzymes, viruses and subcellular structures often form by self-limiting hierarchical oligomerization of multiple subunits. Large structures can also assemble efficiently from a few components by combining hierarchical assembly and symmetry, a strategy exemplified by viral capsids. De novo protein design and RNA and DNA nanotechnology aim to mimic these capabilities, but the bottom-up construction of artificial structures with the dimensions and complexity of viruses and other subcellular components remains challenging...
December 6, 2017: Nature
Julie Seibt, Clément J Richard, Johanna Sigl-Glöckner, Naoya Takahashi, David I Kaplan, Guy Doron, Denis de Limoges, Christina Bocklisch, Matthew E Larkum
In the originally published version of this Article, incorrect references were cited on two occasions in the Results section. Under the subheading 'Ca2+ activity in single dendrites and somata of L5 neurons', the final sentence of the second paragraph incorrectly cited reference 29 instead of reference 31. Under the subheading 'Spiking of L5 cell bodies is not influenced by spindles', the first sentence cited reference 30 instead of reference 29. These errors have now been corrected in both the PDF and HTML versions of the Article...
November 23, 2017: Nature Communications
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