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https://www.readbyqxmd.com/read/28645041/behavioral-and-neural-concordance-in-parent-child-dyadic-sleep-patterns
#1
Tae-Ho Lee, Michelle E Miernicki, Eva H Telzer
Sleep habits developed in adolescence shape long-term trajectories of psychological, educational, and physiological well-being. Adolescents' sleep behaviors are shaped by their parents' sleep at both the behavioral and biological levels. In the current study, we sought to examine how neural concordance in resting-state functional connectivity between parent-child dyads is associated with dyadic concordance in sleep duration and adolescents' sleep quality. To this end, we scanned both parents and their child (N=28 parent-child dyads; parent Mage=42...
June 15, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28645025/decreased-functional-connectivity-and-disrupted-neural-network-in-the-prefrontal-cortex-of-affective-disorders-a-resting-state-fnirs-study
#2
Huilin Zhu, Jie Xu, Jiangxue Li, Hongjun Peng, Tingting Cai, Xinge Li, Shijing Wu, Wei Cao, Sailing He
BACKGROUND: Affective disorders (AD) have been conceptualized as neural network-level diseases. In this study, we utilized functional near infrared spectroscopy (fNIRS) to investigate the spontaneous hemodynamic activities in the prefrontal cortex (PFC) of the AD patients with or without medications. METHODS: 42 optical channels were applied to cover the superior frontal gyrus (SFG), middle frontal gyrus (MFG), and inferior frontal gyrus (IFG), which constitute one of the most important affective networks of the brain...
June 17, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28644996/neural-correlates-of-psychotic-like-experiences-during-spiritual-trance-state
#3
Alessandra Ghinato Mainieri, Julio Fernando Prieto Peres, Alexander Moreira-Almeida, Klaus Mathiak, Ute Habel, Nils Kohn
Recent studies indicate high levels of psychotic experiences in the general population. Here, we report a functional imaging study with 8 mentally healthy spiritual mediums and 8 matched controls. The mediums entered a mediumistic-trance state using a standardized manner by closing their eyes and actively seeking to ignore external and internal stimuli to achieve a 'state of emptiness'; in a control condition, they were instructed to re-enact the same mediumistic experience that they had during the mediumistic-trance condition but in a non-trance state (imaginative-trance)...
June 15, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28643358/maximizing-functional-axon-repair-in-the-injured-cns-lessons-from-neuronal-development
#4
Andrew Kaplan, Mardja Bueno, Luyang Hua, Alyson E Fournier
The failure of damaged axons to regrow underlies disability in central nervous system injury and disease. Therapies that stimulate axon repair will be critical to restore function. Extensive axon regeneration can be induced by manipulation of oncogenes and tumor suppressors, however it has been difficult to translate this into functional recovery in models of spinal cord injury. The current challenge is to maximize the functional integration of regenerating axons to recover motor and sensory behaviours. Insights into axonal growth and wiring during nervous system development are helping guide new approaches to boost regeneration and functional connectivity after injury in the mature nervous system...
June 23, 2017: Developmental Dynamics: An Official Publication of the American Association of Anatomists
https://www.readbyqxmd.com/read/28642938/correlation-weighted-sparse-group-representation-for-brain-network-construction-in-mci-classification
#5
Renping Yu, Han Zhang, Le An, Xiaobo Chen, Zhihui Wei, Dinggang Shen
Analysis of brain functional connectivity network (BFCN) has shown great potential in understanding brain functions and identifying biomarkers for neurological and psychiatric disorders, such as Alzheimer's disease and its early stage, mild cognitive impairment (MCI). In all these applications, the accurate construction of biologically meaningful brain network is critical. Due to the sparse nature of the brain network, sparse learning has been widely used for complex BFCN construction. However, the conventional l1-norm penalty in the sparse learning equally penalizes each edge (or link) of the brain network, which ignores the link strength and could remove strong links in the brain network...
October 2016: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
https://www.readbyqxmd.com/read/28642688/lower-functional-connectivity-of-the-periaqueductal-gray-is-related-to-negative-affect-and-clinical-manifestations-of-fibromyalgia
#6
Marie-Andrée Coulombe, Keith St Lawrence, Dwight E Moulin, Patricia Morley-Forster, Mahsa Shokouhi, Warren R Nielson, Karen D Davis
Fibromyalgia (FM) syndrome is characterized by chronic widespread pain, muscle tenderness and emotional distress. Previous studies found reduced endogenous pain modulation in FM. This deficiency of pain modulation may be related to the attributes of chronic pain and other clinical symptoms experienced in patients with FM. Thus, we tested whether there is a link between the clinical symptoms of FM and functional connectivity (FC) of the periaqueductal gray (PAG), a key node of pain modulation. We acquired resting state 3T functional MRI (rsfMRI) data from 23 female patients with FM and 16 age- and sex- matched healthy controls (HC) and assessed FM symptoms with the Brief Pain Inventory (BPI), Fibromyalgia Impact Questionnaire (FIQ), Hospital Anxiety and Depression Scale (HADS) and Pain Catastrophizing Scale (PCS)...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/28642079/common-and-distinct-brain-networks-underlying-panic-and-social-anxiety-disorders
#7
REVIEW
Yong-Ku Kim, Ho-Kyoung Yoon
Although panic disorder (PD) and phobic disorders are independent anxiety disorders with distinct sets of diagnostic criteria, there is a high level of overlap between them in terms of pathogenesis and neural underpinnings. Functional connectivity research using resting-state functional magnetic resonance imaging (rsfMRI) shows great potential in identifying the similarities and differences between PD and phobias. Understanding common and distinct networks between PD and phobic disorders is critical for identifying both specific and general neural characteristics of these disorders...
June 19, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28640620/using-complementary-nmr-data-sets-to-detect-inconsistencies-and-model-flaws-in-the-structure-determination-of-human-interleukin-4
#8
Lorna J Smith, Wilfred F van Gunsteren, Niels Hansen
The derivation of protein structure from values of observable quantities measured in NMR experiments is a rather non-trivial task due to (i) the limited number of data compared to degrees of freedom of a protein, (ii) the uncertainty inherent to the function connecting an observable quantity to molecular structure, (iii) the finite quality of biomolecular models and force fields used in structure refinement, and (iv) the conformational freedom of a protein in aqueous solution, which requires extensive conformational sampling and appropriate conformational averaging when calculating or restraining to sets of NMR data...
June 22, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28638719/abnormal-amplitude-of-low-frequency-fluctuations-and-functional-connectivity-of-resting-state-functional-magnetic-resonance-imaging-in-patients-with-leukoaraiosis
#9
Rongchuan Cheng, Honglin Qi, Yong Liu, Shifu Zhao, Chuanming Li, Chen Liu, Jian Zheng
INTRODUCTION: This study aimed to investigate the cerebral function deficits in patients with leukoaraiosis (LA) and the correlation with white matter hyperintensity (WMH) using functional MRI (fMRI) technology. MATERIALS AND METHODS: Twenty-eight patients with LA and 30 volunteers were enrolled in this study. All patients underwent structural MRI and resting-state functional MRI (rs-fMRI) scanning. The amplitude of low-frequency fluctuations (ALFF) of rs-fMRI signals for the two groups was compared using two-sample t tests...
June 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28638334/frontal-theta-dynamics-during-response-conflict-in-long-term-mindfulness-meditators
#10
Han-Gue Jo, Peter Malinowski, Stefan Schmidt
Mindfulness meditators often show greater efficiency in resolving response conflicts than non-meditators. However, the neural mechanisms underlying the improved behavioral efficiency are unclear. Here, we investigated frontal theta dynamics-a neural mechanism involved in cognitive control processes-in long-term mindfulness meditators. The dynamics of EEG theta oscillations (4-8 Hz) recorded over the medial frontal cortex (MFC) were examined in terms of their power (MFC theta power) and their functional connectivity with other brain areas (the MFC-centered theta network)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28638117/disrupted-functional-connectivity-between-the-periaqueductal-gray-and-other-brain-regions-in-a-rat-model-of-recurrent-headache
#11
Zhihua Jia, Wenjing Tang, Dengfa Zhao, Shengyuan Yu
Functional connectivity (FC) has been used to investigate the pathophysiology of migraine. We aimed to identify atypical FC between the periaqueductal gray (PAG) and other brain areas in rats induced by repeated meningeal nociception. The rat model was established by infusing an inflammatory soup (IS) through supradural catheters in conscious rats. Quiescent and face-grooming behaviors were observed to assess nociceptive behavior. FC analysis seeded on the PAG was performed on rats 21 days after IS infusion...
June 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28636929/intrinsic-functional-connectivity-alteration-of-dorsal-and-rostral-anterior-cingulate-cortex-in-obsessive-compulsive-disorder-a-resting-fmri-study
#12
Zongfeng Zhang, Qing Fan, Yajing Zhu, Ling Tan, Yongjun Chen, Rui Gao, Haiyin Zhang, Yao Li, Zeping Xiao
Cortico-striato-thalamo-cortical (CSTC) circuit has been implicated in OCD pathophysiology by converging neuroimaging findings. The anterior cingulate cortex (ACC), as an important part within CSTC circuit, plays a critical role in OCD etiology. The ACC can be divided into dorsal and rostral parts anatomically, which are involved in cognitive process and emotional function, respectively. However, the diverse function of intrinsic signals from dorsal and rostral ACC regions remains unclear in OCD study. In this work, we applied resting-state functional magnetic resonance imaging (rs-fMRI) technology to investigate and differentiate the functional connectivity (FC) characteristics between dACC and rACC in unmedicated OCD patients...
June 18, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28635541/association-between-abnormal-brain-functional-connectivity-in-children-and-psychopathology-a-study-based-on-graph-theory-and-machine-learning
#13
João Ricardo Sato, Claudinei Eduardo Biazoli, Giovanni Abrahão Salum, Ary Gadelha, Nicolas Crossley, Gilson Vieira, André Zugman, Felipe Almeida Picon, Pedro Mario Pan, Marcelo Queiroz Hoexter, Edson Amaro, Mauricio Anés, Luciana Monteiro Moura, Marco Antonio Gomes Del'Aquilla, Philip Mcguire, Luis Augusto Rohde, Euripedes Constantino Miguel, Andrea Parolin Jackowski, Rodrigo Affonseca Bressan
OBJECTIVES: One of the major challenges facing psychiatry is how to incorporate biological measures in the classification of mental health disorders. Many of these disorders affect brain development and its connectivity. In this study, we propose a novel method for assessing brain networks based on the combination of a graph theory measure (eigenvector centrality) and a one-class support vector machine (OC-SVM). METHODS: We applied this approach to resting-state fMRI data from 622 children and adolescents...
February 8, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/28634465/abnormal-resting-state-functional-connectivity-in-progressive-supranuclear-palsy-and-corticobasal-syndrome
#14
Komal Bharti, Matteo Bologna, Neeraj Upadhyay, Maria Cristina Piattella, Antonio Suppa, Nikolaos Petsas, Costanza Giannì, Francesca Tona, Alfredo Berardelli, Patrizia Pantano
BACKGROUND: Pathological and MRI-based evidence suggests that multiple brain structures are likely to be involved in functional disconnection between brain areas. Few studies have investigated resting-state functional connectivity (rsFC) in progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). In this study, we investigated within- and between-network rsFC abnormalities in these two conditions. METHODS: Twenty patients with PSP, 11 patients with CBS, and 16 healthy subjects (HS) underwent a resting-state fMRI study...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28633369/fine-subdivisions-of-the-semantic-network-supporting-social-and-sensory-motor-semantic-processing
#15
Nan Lin, Xiaoying Wang, Yangwen Xu, Xiaosha Wang, Huimin Hua, Ying Zhao, Xingshan Li
Neuroimaging studies have consistently indicated that semantic processing involves a brain network consisting of multimodal cortical regions distributed in the frontal, parietal, and temporal lobes. However, little is known about how semantic information is organized and processed within the network. Some recent studies have indicated that sensory-motor semantic information modulates the activation of this network. Other studies have indicated that this network responds more to social semantic information than to other information...
June 15, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28633076/resting-state-functional-connectivity-of-anterior-and-posterior-hippocampus-in-posttraumatic-stress-disorder
#16
Amit Lazarov, Xi Zhu, Benjamin Suarez-Jimenez, Bret R Rutherford, Yuval Neria
Posttraumatic stress disorder (PTSD) has been associated with altered resting-state functional connectivity (rs-FC) of several brain regions within the salience (SN) and default-mode (DMN) networks, including the hippocampus. However, most rs-FC studies have not focused primarily on the hippocampus, nor have they appreciated its structural heterogeneity, despite clear evidence for a dissociation between posterior and anterior hippocampal connectivity. Here, we examine rs-FC of anterior and posterior hippocampus with key regions in the SN (amygdala, insula, and dorsal anterior cingulate cortex/pre-supplementary motor area) and DMN (ventromedial prefrontal cortex, posterior cingulate cortex, and precuneus) previously implicated in PTSD, using a seed-based approach...
June 13, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28633048/affective-traits-and-history-of-depression-are-related-to-ventral-striatum-connectivity
#17
Sophie R DelDonno, Lisanne M Jenkins, Natania A Crane, Robin Nusslock, Kelly A Ryan, Stewart A Shankman, K Luan Phan, Scott A Langenecker
INTRODUCTION: Studying remitted Major Depressive Disorder (rMDD) facilitates a better understanding of neural mechanisms for risk, given that confounding effects of active symptoms are removed. Disrupted functional connectivity has been reported in multiple networks in MDD. However, no study to date of rMDD has specifically examined connectivity of the ventral striatum (VS), a region highly implicated in reward and motivation. We investigated functional connectivity of the VS in individuals with and without a history of MDD, and in relation to affective personality traits...
June 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28632120/basolateral-amygdala-ventromedial-prefrontal-cortex-connectivity-predicts-cognitive-behavioural-therapy-outcome-in-adults-with-obsessive-compulsive-disorder
#18
Miquel A Fullana, Xi Zhu, Pino Alonso, Narcís Cardoner, Eva Real, Clara López-Solà, Cinto Segalàs, Marta Subirà, Hanga Galfalvy, José M Menchón, H Blair Simpson, Rachel Marsh, Carles Soriano-Mas
BACKGROUND: Cognitive behavioural therapy (CBT), including exposure and ritual prevention, is a first-line treatment for obsessive-compulsive disorder (OCD), but few reliable predictors of CBT outcome have been identified. Based on research in animal models, we hypothesized that individual differences in basolateral amygdala-ventromedial prefrontal cortex (BLA-vmPFC) communication would predict CBT outcome in patients with OCD. METHODS: We investigated whether BLA-vmPFC resting-state functional connectivity (rs-fc) predicts CBT outcome in patients with OCD...
June 20, 2017: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/28631354/cross-population-myelination-covariance-of-human-cerebral-cortex
#19
Zhiwei Ma, Nanyin Zhang
Cross-population covariance of brain morphometric quantities provides a measure of interareal connectivity, as it is believed to be determined by the coordinated neurodevelopment of connected brain regions. Although useful, structural covariance analysis predominantly employed bulky morphological measures with mixed compartments, whereas studies of the structural covariance of any specific subdivisions such as myelin are rare. Characterizing myelination covariance is of interest, as it will reveal connectivity patterns determined by coordinated development of myeloarchitecture between brain regions...
June 20, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28631281/detecting-large-scale-networks-in-the-human-brain-using-high-density-electroencephalography
#20
Quanying Liu, Seyedehrezvan Farahibozorg, Camillo Porcaro, Nicole Wenderoth, Dante Mantini
High-density electroencephalography (hdEEG) is an emerging brain imaging technique that can be used to investigate fast dynamics of electrical activity in the healthy and the diseased human brain. Its applications are however currently limited by a number of methodological issues, among which the difficulty in obtaining accurate source localizations. In particular, these issues have so far prevented EEG studies from reporting brain networks similar to those previously detected by functional magnetic resonance imaging (fMRI)...
June 20, 2017: Human Brain Mapping
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