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https://www.readbyqxmd.com/read/30517723/men-and-women-differ-in-gastric-fluid-retention-and-neural-activation-after-consumption-of-carbonated-beverages
#1
Guido Camps, Kees de Graaf, Paul A M Smeets
Background: The most commonly consumed carbonated beverages are soda and beer. Carbon dioxide increases gastric volume, which can lead to epigastric discomfort. Women are more susceptible to this; however, correlations with neural activity and gastric distention are unknown. Objective: This study sought to determine the subjective, gastric, and neural correlates of epigastric discomfort in men and women. Methods: Thirty-four healthy, normal-weight adults [17 women; mean ± SD body mass index (BMI; kg/m2): 22...
December 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/30512969/pulicaria-crispa-mitigates-gastric-ulcer-induced-by-ethanol-in-rats-role-of-treatment-and-auto-healing
#2
Abdelgawad A Fahmi, Mariam Abdur-Rahman, Asmaa F Aboul-Naser, Manal A Hamed, Howida I Abd-Alla, Mohamed I Nasr
CONTEXT: Stomach ulcers are the common gastrointestinal disorders worldwide. OBJECTIVE: This study aimed to investigate the therapeutic impact of Pulicaria crispa aerial part ethanol extract against gastric ulcer in rats. MATERIALS AND METHODS: Ulcer was induced by one oral dose of ethanol (0.5 ml/100g body weight) on 24 hours empty stomach, then the plant extract (500 mg/kg b.wt.) was orally administered daily for one week. Ranitidine (100mg/kg b...
December 4, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/30510365/a-comparative-study-of-totally-laparoscopic-distal-gastrectomy-versus-laparoscopic-assisted-distal-gastrectomy-in-gastric-cancer-patients-short-term-operative-outcomes-at-a-high-volume-center
#3
Won Ho Han, Amir Ben Yehuda, Deok-Hee Kim, Seung Geun Yang, Bang Wool Eom, Hong Man Yoon, Young-Woo Kim, Keun Won Ryu
Objective: Laparoscopic gastrectomy has been established as a standard treatment for early gastric cancer, and its use is increasing recently. Compared with the conventional laparoscopy-assisted distal gastrectomy (LADG), totally laparoscopic distal gastrectomy (TLDG) involves intracorporeal reconstruction, which can avoid the additional incision, resulting in pain reduction and early recovery. This study aimed to compare the short-term postoperative outcomes of TLDG vs. LADG in gastric cancer in a high-volume center...
October 2018: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/30509287/volumetric-decrease-of-pancreas-after-abdominal-irradiation-it-is-time-to-consider-pancreas-as-an-organ-at-risk-for-radiotherapy-planning
#4
Cengiz Gemici, Gokhan Yaprak, Sevim Ozdemir, Tamer Baysal, Ozgur Ozan Seseogullari, Hazan Ozyurt
BACKGROUND: Volumetric shrinkage of normal tissues such as salivary glands, kidneys, hippocampus are observed after radiotherapy. We aimed to assess the alterations in pancreatic volume of patients who received abdominal radiotherapy and define pancreas as an organ at risk for radiation treatment planning. MATERIAL-METHODS: Forty-nine patients operated for gastric adenocarcinoma who received adjuvant abdominal radiotherapy were in the study group, 27 patients with early stage disease who did not need adjuvant treatment after surgery comprised the control group...
December 3, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/30508254/incidence-and-effects-of-feeding-intolerance-in-trauma-patients
#5
Farrukh R Virani, Travis Peery, Orlyn Rivas, Jeffrey Tomasek, Ravin Huerta, Charles E Wade, Jenny Lee, John B Holcomb, Karen Uray
BACKGROUND: Although feeding intolerance is a common complication in trauma patients, the incidence, development, and effects are poorly understood. METHODS: We performed a retrospective study in which trauma patients were classified as having feeding intolerance based on time to reach feeding goal. Subsequently, we sorted patients by gastric residual volumes (GRVs) or symptoms of slowed gastrointestinal motility. RESULTS: One-third of trauma patients experienced delayed time to reach feeding goal after diet initiation...
December 3, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/30489670/wikistim-org-an-on-line-database-of-published-neurostimulation-studies
#6
Richard B North, Jane Shipley
INTRODUCTION: Primary data reported in scientific publications provide guidance for improving patient care, expanding indications, identifying research gaps, educating patients, justifying reimbursement, and gaining regulatory approval. Finding and analyzing pertinent publications among the huge volume noted in databases such as PUBMED, however, costs time and effort. This situation demands innovative ways to locate citations of (and the possibility of abstracting data from) papers reporting primary findings...
November 29, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/30487757/effect-of-abdominal-binding-on-diaphragmatic-neuromuscular-efficiency-exertional-breathlessness-and-exercise-endurance-in-chronic-obstructive-pulmonary-disease
#7
Sara J Abdallah, Benjamin M Smith, Courtney Wilkinson-Maitland, Pei Zhi Li, Jean Bourbeau, Dennis Jensen
We tested the hypothesis that abdominal binding (AB) would reduce breathlessness and improve exercise tolerance by enhancing neuromuscular efficiency of the diaphragm during exercise in adults with chronic obstructive pulmonary disease (COPD). In a randomized, controlled, crossover trial, 20 adults with COPD (mean ± SD FEV1 , 60 ± 16% predicted) completed a symptom-limited constant-load cycle endurance exercise test at 75% of their peak incremental power output with concomitant measures of the diaphragm electromyogram (EMGdi) and respiratory pressures without (CTRL) vs...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/30483970/the-learning-curve-for-a-surgeon-in-robot-assisted-laparoscopic-pancreaticoduodenectomy-a-retrospective-study-in-a-high-volume-pancreatic-center
#8
Tao Zhang, Zhi-Ming Zhao, Yuan-Xing Gao, Wan Yee Lau, Rong Liu
BACKGROUND: Pancreaticoduodenectomy (PD) is one of the most technically difficult abdominal operations. Recent advances have allowed surgeons to attempt PD using minimally invasive surgery techniques. This retrospective study aimed to analyze the learning curve of a single surgeon who had carried out his first 100 robot-assisted laparoscopic pancreaticoduodenectomy (RPD) in a high-volume pancreatic center. METHODS: The data on consecutive patients who underwent RPD for malignant or benign pathologies were prospectively collected and retrospectively analyzed...
November 27, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30483969/clinicopathological-features-and-prognosis-of-276-cases-of-primary-small-%C3%A2-2-cm-gastric-gastrointestinal-stromal-tumors-a-multicenter-data-review
#9
Zifeng Yang, Xingyu Feng, Peng Zhang, Tao Chen, Haibo Qiu, Zhiwei Zhou, Guoxin Li, Kai Xiong Tao, Yong Li
BACKGROUND: Till present, there are still controversies over the epidemiology, pathological features, types of surgical treatment, and prognoses of primary small gastric GISTs (gGISTs). METHODS: From January 1998 to January 2015, patients with primary small gGIST admitted from four high-volume medical centers of the Southern China were enrolled and their data were analyzed to evaluate their clinicopathological features, treatment and prognostic factors to provide evidence-based medical experience for clinical practice...
November 27, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30479760/high-resected-gastric-volume-and-poorly-controlled-dm2-in-laparoscopic-sleeve-gastrectomy
#10
Federico Sista, Valentina Abruzzese, Stefano Guadagni, Sergio Carandina, Marco Clementi
Background: Our aim is to evaluate the effects of High Resected Gastric Volume(HRGV) on poorly Type 2 Diabetes Mellitus(DM2) after Laparoscopic Sleeve Gastrectomy(LSG). Methods: 256 patients were divided into two groups according to the RGV: < 1500 mL(Group A: 131 pts) and > 1500 mL(Group B: 147 pts). % excess body mass index loss (%EBMIL), Fasting Blood Glucose (FBG), HbA1c, C peptide were assessed before surgery and at the 3rd day, 6th,12th,24th,36th month after LSG...
December 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/30479581/feasibility-of-intensity-modulated-radiotherapy-to-treat-gastric-cancer
#11
Agnieszka Skrobala, Marta Adamczyk, Aldona Karczewska-Dzionk
Aim: To present a proposed gastric cancer intensity-modulated radiotherapy (IMRT) treatment planning protocol for an institution that have not introduced volumetric modulated arc therapy in clinical practice. A secondary aim was to determine the impact of 2DkV set-up corrections on target coverage and organ at risk (OAR). Methods and Materials: Twenty consecutive patients were treated with a specially-designed non-coplanar 7-field IMRT technique. The isocenter-shift method was used to estimate the impact of 2DkV-based set-up corrections on the original base plan (BP) coverage...
January 2019: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/30479486/perioperative-enteral-nutrition-after-left-ventricular-assist-device-implantation
#12
Ryuichiro Abe, Atsuhiro Matsumoto, Ryota Sakaguchi, Koichi Toda, Yoshiki Sawa, Akinori Uchiyama, Yuji Fujino
Objective: We assessed what predicts nutritional adequacy at day 14 following implantation of left ventricular assist device (LVAD). Method: We retrospectively reviewed the cases of 97 adult patients who underwent LVAD implantation at our institution from June 2011 to June 2016. We divided the patients into two groups based on the administered enteral nutrition (EN) calories on post-operative day (POD) 14: the EN calories of group SEN (sufficient enteral nutrition) were >80% of their total target calories, or the EN calories of group IEN (insufficient enteral nutrition) were <80% of their total target calories...
2018: Nutrition and Metabolic Insights
https://www.readbyqxmd.com/read/30478700/-four-step-procedure-of-laparoscopic-exploration-for-gastric-cancer-in-west-china-hospital-a-retrospective-observational-analysis-from-a-high-volume-institution-in-china
#13
Kai Liu, Xin-Zu Chen, Wei-Han Zhang, Dong-Yang Zhang, Yi Luo, Yue Yu, Kun Yang, Shi-Jie Yang, Xiao-Long Chen, Li-Fei Sun, Lin-Yong Zhao, Zong-Guang Zhou, Jian-Kun Hu
BACKGROUND: The preoperative work-up has limitations on finding peritoneal dissemination (PD) in gastric cancer patients. Laparoscopic exploration (LE) can discover radiographically occult PD, obtain accurate stage and avert futile laparotomy. The aim of our study was to introduce "Four-Step Procedure" LE in West China Hospital and further evaluate its safety and feasibility. METHODS: We conducted a retrospective analysis on 165 patients from July 2016 to December 2017 who underwent "Four-Step Procedure" LE in gastrointestinal surgery department of West China Hospital...
November 26, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30477963/-pharmacological-profile-of-isavuconazole
#14
José Ramón Azanza Perea, Belén Sádaba Díaz de Rada
Isavuconazole is a new azole, structurally related to fluconazole and voriconazole, that presents a very high oral absorption with no first-pass effect which is not interfered by the presence of food, gastric pH modifications, or mucositis. Its distribution volume is very high, probably also to cerebrospinal fluid, in spite of the fact that it circulates highly bound to plasma proteins. It is extensively metabolized through the CYP3A4 isoenzyme. Due to this reason, it is recommended to avoid co-administration with strong CYP3A4 inducers...
November 23, 2018: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/30474028/evaluating-clinical-genome-sequence-analysis-by-watson-for-genomics
#15
Kota Itahashi, Shunsuke Kondo, Takashi Kubo, Yutaka Fujiwara, Mamoru Kato, Hitoshi Ichikawa, Takahiko Koyama, Reitaro Tokumasu, Jia Xu, Claudia S Huettner, Vanessa V Michelini, Laxmi Parida, Takashi Kohno, Noboru Yamamoto
Background: Oncologists increasingly rely on clinical genome sequencing to pursue effective, molecularly targeted therapies. This study assesses the validity and utility of the artificial intelligence Watson for Genomics (WfG) for analyzing clinical sequencing results. Methods: This study identified patients with solid tumors who participated in in-house genome sequencing projects at a single cancer specialty hospital between April 2013 and October 2016. Targeted genome sequencing results of these patients' tumors, previously analyzed by multidisciplinary specialists at the hospital, were reanalyzed by WfG...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/30473775/computational-assessment-of-stomach-tumor-volume-from-multi-slice-computerized-tomography-images-in-presence-of-type-2-cancer
#16
Gerardo Chacón, Johel E Rodríguez, Valmore Bermúdez, Miguel Vera, Juan Diego Hernández, Sandra Vargas, Aldo Pardo, Carlos Lameda, Delia Madriz, Antonio J Bravo
Background: The multi-slice computerized tomography (MSCT) is a medical imaging modality that has been used to determine the size and location of the stomach cancer. Additionally, MSCT is considered the best modality for the staging of gastric cancer. One way to assess the type 2 cancer of stomach is by detecting the pathological structure with an image segmentation approach. The tumor segmentation of MSCT gastric cancer images enables the diagnosis of the disease condition, for a given patient, without using an invasive method as surgical intervention...
2018: F1000Research
https://www.readbyqxmd.com/read/30473706/feasibility-safety-and-efficacy-of-pressurized-intraperitoneal-aerosol-chemotherapy-pipac-for-peritoneal-metastasis-a-registry-study
#17
Florian Kurtz, Florian Struller, Philipp Horvath, Wiebke Solass, Hans Bösmüller, Alfred Königsrainer, Marc A Reymond
Introduction: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel drug delivery system with superior pharmacological properties for treating peritoneal metastasis (PM). Safety and efficacy results of PIPAC with cisplatin/doxorubicin or oxaliplatin from a registry cohort are presented. Methods: IRB-approved registry study. Retrospective analysis. No predefined inclusion criteria, individual therapeutic recommendation by the interdisciplinary tumor board...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/30472473/bioavailability-speciation-of-arsenic-in-atmospheric-pm-2-5-and-their-seasonal-variation-a-case-study-in-baoding-city-china
#18
Jiao-Jiao Xie, Chun-Gang Yuan, Yi-Wen Shen, Jin Xie, Kai-Qiang He, Hong-Tao Zhu, Ke-Gang Zhang
Arsenic (As) can be easily enriched in atmospheric particulate matters (PMs), especially in fine particulate matters (PM2.5 ). In this study, thirty two PM2.5 samples were collected in four seasons in Baoding, China, where the haze pollution was very serious in recent years. The total contents, species and bioavailability of arsenic in PM2.5 samples were investigated. Species of arsenic in the PM2.5 samples were discriminated as five fractions using a sequential extraction method: non-specifically sorbed fraction (F1), specifically-sorbed fraction (F2), amorphous and poorly-crystalline hydrous oxides of Fe and Al fraction (F3), well-crystallized hydrous oxides of Fe and Al fraction (F4) and residual fraction (F5)...
November 22, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/30471928/preoperative-liver-shrinking-diet-for-bariatric-surgery-may-impact-wound-healing-a-randomized-controlled-trial
#19
Saurav Chakravartty, Gillian Vivian, Nicola Mullholland, Hizbullah Shaikh, John McGrath, Paul S Sidhu, Ounali Jaffer, Ameet G Patel
BACKGROUND: In bariatric surgery, preoperative very low-calorie diets (VLCD) may better meet the technical demands of surgery by shrinking the liver. However, diets may affect tissue healing and influence bowel anastomosis in an as-yet-undefined manner. OBJECTIVE: This randomized controlled trial aimed to examine the effect on collagen deposition in wounds in patients on a 4-week VLCD before laparoscopic gastric bypass. SETTING: University hospital...
October 12, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/30468310/retraction
#20
(no author information available yet)
"si-RNA-Mediated Knockdown of PDLIM5 Suppresses Gastric Cancer Cell Proliferation in Vitro" by Yanliang Li, Yongsheng Gao, Yue Xu, Xianjun Sun, Xilin Song, Heng Ma & Mingshan Yang.[1] The above article from Chemical Biology & Drug Design, published online on September 12, 2014 in Wiley Online Library (http://onlinelibrary.wiley.com), and in Volume 85, pp. 447-453, has been retracted by agreement between the journal Editor in Chief David Selwood, and John Wiley and Sons Ltd. The retraction has been agreed upon following the realisation that there are several serious errors with this paper with incorrect shRNA sequences being used...
December 2018: Chemical Biology & Drug Design
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