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https://www.readbyqxmd.com/read/30101365/management-and-outcome-of-multifetal-gestation-in-a-35-year-old-woman-with-childhood-onset-membranoproliferative-glomerulonephritis-type-i
#1
Osamu Motoyama, Ken Sakai, Kikuo Iitaka
A 35-year-old woman with membranoproliferative glomerulonephritis type I had quintuplet gestation after induced ovulation. Her serum creatinine level and estimated glomerular filtration rate were 0.86 mg/dL and 61.5 mL/min/1.73 m2 before pregnancy. Blood pressure was normal and urinary protein to creatinine ratio was 0.2 g/gCr. Prednisolone 10 mg on alternate-day administration was continued during pregnancy. At 10 weeks of gestation transvaginal selective embryo reduction was performed and five embryos were reduced to twins...
August 12, 2018: CEN Case Reports
https://www.readbyqxmd.com/read/30098014/patterns-of-use-and-optimal-timing-of-antenatal-corticosteroids-in-twin-compared-to-singleton-pregnancies
#2
Amihai Rottenstreich, Gabriel Levin, Geffen Kleinstern, Rani Haj Yahya, Misgav Rottenstreich, Simcha Yagel, Uriel Elchalal
INTRODUCTION: Previous reports have shown that suboptimal antenatal corticosteroids administration occurs in most cases. However, as multifetal gestations were either excluded or constituted a small proportion of the subjects in these studies, little is known about the patterns of use of antenatal corticosteroids in twin pregnancies. MATERIAL AND METHODS: We reviewed the records of women who received antenatal corticosteroids and delivered between 240/7 and 346/7 weeks of gestation during 2015-2017 at two university hospitals...
August 11, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/30065540/outcomes-of-multifetal-reduction-a-hospital-based-study
#3
Madhusudan Dey, Monica Saraswat
Background: Higher-order multiple (HOM) pregnancies are associated with increased incidences of pregnancy complications mainly abortions, pre-eclampsia, preterm delivery and fetal death. Multifetal reduction (MFR) during first trimester and subsequent delivery of twins can reduce pregnancy associated morbidities. This study was conducted to evaluate the maternal and fetal outcomes of MFR procedure in patients with HOMs those managed in a tertiary care hospital. Methods and Material: It was a prospective observational study carried out in a tertiary care military hospital, India, and all women with higher-order multiples (triplets or more) conceived spontaneously or after infertility treatment (ovulation induction, intra-uterine insemination, or in vitro fertilization) during the 3-year period from Jan 2014 to Dec 2016 were included for MFR...
August 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29939940/acog-committee-opinion-no-743-low-dose-aspirin-use-during-pregnancy
#4
(no author information available yet)
Low-dose aspirin has been used during pregnancy, most commonly to prevent or delay the onset of preeclampsia. The American College of Obstetricians and Gynecologists issued the Hypertension in Pregnancy Task Force Report recommending daily low-dose aspirin beginning in the late first trimester for women with a history of early-onset preeclampsia and preterm delivery at less than 34 0/7 weeks of gestation, or for women with more than one prior pregnancy complicated by preeclampsia. The U.S. Preventive Services Task Force published a similar guideline, although the list of indications for low-dose aspirin use was more expansive...
July 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29939936/acog-committee-opinion-no-743-summary-low-dose-aspirin-use-during-pregnancy
#5
(no author information available yet)
Low-dose aspirin has been used during pregnancy, most commonly to prevent or delay the onset of preeclampsia. The American College of Obstetricians and Gynecologists issued the Hypertension in Pregnancy Task Force Report recommending daily low-dose aspirin beginning in the late first trimester for women with a history of early-onset preeclampsia and preterm delivery at less than 34 0/7 weeks of gestation, or for women with more than one prior pregnancy complicated by preeclampsia. The U.S. Preventive Services Task Force published a similar guideline, although the list of indications for low-dose aspirin use was more expansive...
July 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29859779/could-fetal-reduction-induce-facial-cleft-report-of-a-case
#6
J Chauvel-Picard, J Massardier, A Gleizal
We describe a paramedian cleft of the lower lip that cannot be explained by embryological development in a child with only one predisposing factor, which was fetal reduction for a multiple pregnancy. To the best of our knowledge, there has been no report of a cleft that has been induced by the reduction of a multifetal pregnancy.
July 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29642747/elevated-maternal-serum-free-%C3%AE-human-chorionic-gonadotropin-%C3%AE-hcg-and-reduced-risk-of-spontaneous-preterm-delivery
#7
Shelly Soni, David A Krantz, Matthew J Blitz, Nidhi Vohra, Burton Rochelson
OBJECTIVE: To evaluate the relationship between first and second trimester maternal serum-free β-hCG and the risk of spontaneous preterm delivery (PTD). STUDY DESIGN: This was a case-control study of women evaluated and delivered at our institution from 2011 to 2015. Spontaneous PTD was defined as delivery before 37 weeks due to spontaneous preterm labor or premature rupture of membranes. Patient with multifetal gestation and those with medically indicated term or PTD were excluded...
April 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29629925/reducing-maternal-mortality-and-severe-maternal-morbidity-the-role-of-critical-care
#8
Amir A Shamshirsaz, Gary A Dildy
Throughout most of the 20th century, the risk of maternal mortality in high resource countries decreased dramatically; however, this trend recently has stalled in the United States and appears to have reversed. Equally alarming is that for every reported maternal death, there are numerous severe maternal morbidities or near misses. Shifting maternal demographics (eg, obesity, advanced maternal age, multifetal pregnancies), with attendant significant medical comorbidities (eg, hypertension, diabetes, cardiac disease) and the increase in cesarean deliveries significantly contribute to increased maternal morbidity and mortality...
June 2018: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29418029/procedural-and-obstetrical-outcomes-after-embryo-reduction-or-fetal-reduction-in-multifetal-pregnancies-a-retrospective-study
#9
Mi Sun Kim, Dong Hee Choi, Hwang Kwon, Eunhee Ahn, Hee Young Cho, Min Jung Baek, Ji Eun Shin, Myoung Jin Moon
OBJECTIVES: Few studies have compared embryo reduction (ER) and fetal reduction (FR) for multifetal pregnancy reduction (MPR). This study investigated the procedure-related adverse events and the obstetrical outcomes in women with multifetal pregnancies (MPs) in whom MPRs to twins or a single fetus were performed at different gestational ages. METHODS: We retrospectively analyzed the data from MPs on which transvaginal ER (n = 181) at a mean gestational age of 7...
February 8, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29411344/maternal-and-perinatal-outcomes-of-dichorionic-diamniotic-twin-pregnancies-diagnosed-with-vanishing-twin-syndrome-a-retrospective-analysis-from-a-single-clinical-center
#10
Hakan Timur, Rifat Taner Aksoy, Aytekin Tokmak, Burcu Timur, Bugra Coskun, Dilek Uygur, Nuri Danisman
OBJECTIVES: Multiple pregnancies are known to be associated with adverse maternal and perinatal complications. How-ever, data regarding the outcomes of spontaneously reduced twin pregnancies are limited. In the current study we aimed to evaluate the consequences of the vanishing twin syndrome (VTS) in dichorionic diamniotic twin pregnancies for both mother and baby in our perinatal center. MATERIAL AND METHODS: A total of 711 pregnancies were included into the study...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29363371/the-impact-of-cerclage-in-twin-pregnancies-on-preterm-birth-rate-before-32-weeks
#11
Michelle N Han, Betsy E O'Donnell, Melanie M Maykin, Juan M Gonzalez, Khalil Tabsh, Stephanie L Gaw
PURPOSE: To evaluate whether cerclage in twins reduces the rate of spontaneous preterm birth <32 weeks when compared to expectant management. METHODS: This is a retrospective cohort study of twin pregnancies with the following indications for cerclage from two institutions: history of prior preterm birth, ultrasound-identified short cervix ≤2.5 cm, and cervical dilation ≥1.0 cm. The "cerclage" cohort received a cerclage from a single provider at a single institution from 2003-2016...
January 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29323608/the-association-between-low-50-g-glucose-challenge-test-values-and-adverse-pregnancy-outcomes
#12
Hayan Kwon, Joonho Lee, Byung-Wan Lee, Ja-Young Kwon, Young-Han Kim
BACKGROUND: The implications of low values on the 50 g glucose challenge test (GCT) in pregnancy are not clearly defined. Few studies have evaluated the influence of maternal low GCT values on obstetrical outcomes. This study aimed to compare pregnancy outcomes between women with low 50 g GCT values and those with normal values. MATERIALS AND METHODS: Women undergoing gestational diabetes mellitus screening at 24-28 weeks of gestational age between January 2010 and December 2016 were retrospectively evaluated...
June 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29166804/adolescence-and-risk-of-preterm-birth-in-multifetal-gestations
#13
Layan Alrahmani, Zaid M Abdelsattar, Henry Adekola, Bernard Gonik, Awoniyi Awonuga
OBJECTIVE: The objective of this study is to evaluate if adolescence confers additional risk for preterm delivery in multifetal gestations. METHODS: This is a retrospective review of all twin and triplet deliveries from 8/2008 to 12/2012 at two Detroit Hospitals. Outcomes in adolescent mothers aged 19 or younger (n = 59) were compared with adult controls aged 20-34 (n = 350). RESULTS: Mean gestational age at delivery in adolescents was 31...
November 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29153659/a-simple-clinical-method-to-identify-women-at-higher-risk-of-preeclampsia
#14
Effie Viguiliouk, Alison L Park, Howard Berger, Michael P Geary, Joel G Ray
An outstanding issue is how to efficiently identify women at high risk of preeclampsia. This retrospective cohort study included 8672 pregnancies at a single centre in Toronto. We tested our simple method - presence vs. absence of≥1 major (pre-pregnancy BMI>30kg/m2 , chronic hypertension, pre-pregnancy diabetes mellitus and assisted reproductive therapy) or≥2 minor (prior stillbirth, age>40years, nulliparity, multifetal pregnancy, chronic kidney disease, and SLE) risk factors for PE. The RR of PE was 8...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29125628/genomics-based-non-invasive-prenatal-testing-for-detection-of-fetal-chromosomal-aneuploidy-in-pregnant-women
#15
REVIEW
Mylène Badeau, Carmen Lindsay, Jonatan Blais, Leon Nshimyumukiza, Yemisi Takwoingi, Sylvie Langlois, France Légaré, Yves Giguère, Alexis F Turgeon, William Witteman, François Rousseau
BACKGROUND: Common fetal aneuploidies include Down syndrome (trisomy 21 or T21), Edward syndrome (trisomy 18 or T18), Patau syndrome (trisomy 13 or T13), Turner syndrome (45,X), Klinefelter syndrome (47,XXY), Triple X syndrome (47,XXX) and 47,XYY syndrome (47,XYY). Prenatal screening for fetal aneuploidies is standard care in many countries, but current biochemical and ultrasound tests have high false negative and false positive rates. The discovery of fetal circulating cell-free DNA (ccfDNA) in maternal blood offers the potential for genomics-based non-invasive prenatal testing (gNIPT) as a more accurate screening method...
November 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29115085/prediction-of-amnionicity-using-the-number-of-yolk-sacs-in-monochorionic-multifetal-pregnancy
#16
Sue Yeon Park, Jin Hoon Chung, You Jung Han, Si Won Lee, Moon Young Kim
The purpose of this article was to evaluate the accuracy of predicting amnionicity using the number of yolk sacs by diagnostic ultrasound examination in monochorionic (MC) multifetal pregnancies between 7 + 0 and 9 + 6 gestational weeks. A total of 97 patients with MC multifetal pregnancies underwent early ultrasound examination from 2004 to 2014 at Cheil General Hospital and Women's Healthcare Center. All patients for whom the number of yolk sacs was reported were included in this study. We compared the number of yolk sacs with amnionicity confirmed by an intertwine membrane...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29069285/transabdominal-ultrasound-guided-multifetal-pregnancy-reduction-in-10-cases-of-monkeys
#17
Yan Zhuo, Shuqing Feng, Shaoyong Huang, Xinglong Chen, Yu Kang, Chenyang Si, Zifan Li, Yin Zhou, Ling Zhou, Ting Zhang, Weizhi Ji, Yuyu Niu, Yongchang Chen
Intracytoplasmic sperm injection (ICSI) and embryo transfer (ET) in nonhuman primates, e.g. rhesus and cynomolgus monkeys, has been widely used in researches of reproductive and developmental biology, and the success rate has been improved significantly. However, unwanted multiple pregnancy occurs frequently during the ICSI-ET in monkeys, most of which leads to miscarriages. To improve the birth rate of pregnancies and to safeguard health of host and baby monkeys, multifetal pregnancy reduction (MPR) is necessary...
November 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29049219/risk-assessment-of-morbidly-obese-parturient-in-cesarean-section-delivery-a-prospective-cohort-single-center-study
#18
Xiaohu An, Yanhong Zhao, Ying Zhang, Qiling Yang, Yilong Wang, Weiwei Cheng, Zeyong Yang
BACKGROUND: Up to 40% of women gain excessive weight during pregnancy. Obesity complications and risks in parturient women undergoing cesarean section (CS) with different anesthetic methods remain unknown. This study aimed to assess the safety and risk of obese women undergoing CS delivery with various perioperative anesthetic methods. METHODS: Seven hundred ninety parturient women underwent CS under general anesthesia (GA), intraspinal anesthesia including epidural anesthesia (EA) and combined spinal-epidural anesthesia (CSEA)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28899350/epidemiological-profile-and-obstetric-outcomes-of-patients-with-peripartum-congestive-heart-failure-in-taiwan-a-retrospective-nationwide-study
#19
Ying-Jen Chang, Chung-Han Ho, Jen-Yin Chen, Ming-Ping Wu, Chia-Hung Yu, Jhi-Joung Wang, Chia-Ming Chen, Chin-Chen Chu
BACKGROUND: During pregnancy, the hyperdynamic physiology of circulation can exacerbate many cardiovascular disorders. Congestive heart failure (CHF) usually occurs during late pregnancy, which is significantly associated with a high level of maternal and neonatal morbidities and mortalities. The profile of women who develop peripartum CHF (PCHF) is unknown. We investigated the epidemiological profiles of PCHF. METHODS: In this retrospective cohort study, PCHF patients were identified using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes in Taiwan's National Health Insurance Research Database...
September 12, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28889767/delayed-interval-delivery-in-twin-pregnancies-report-of-three-cases-and-literature-review
#20
Marta Benito Vielba, Carlos De Bonrostro Torralba, Victoria Pallares Arnal, Rebeca Herrero Serrano, Eva Lucía Tejero Cabrejas, Jose Manuel Campillos Maza
INTRODUCTION: Delayed delivery is sometimes performed in selected multifetal pregnancies when the first twin birth occurs inevitably. The aim of this procedure is to improve the prognosis and decrease the morbidity and mortality of the second twin. We report three cases of delayed-interval delivery of dichorionic-diamniotic twin pregnancies assisted in our center between 2015 and 2017. After the first twin delivery, the second twin was left in utero and the patient received tocolytic therapy and antibiotics...
October 5, 2017: Journal of Maternal-fetal & Neonatal Medicine
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