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Dual energy CT

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https://www.readbyqxmd.com/read/29148698/chelator-free-conjugation-of-99mtc-and-gd3-to-pegylated-nanographene-oxide-for-dual-modality-spect-mr-imaging-of-lymph-nodes
#1
Tianye Cao, Xiaobao Zhou, Yingying Zheng, Yuyun Sun, Jian Zhang, Wei Chen, Jianping Zhang, Zhiguo Zhou, Shi-Ping Yang, Yingjian Zhang, Hong Yang, Ming-Wei Wang
PEGylated ultra-small nanographene oxide (usNGO-PEG) has exhibited great potential in nanotheranostics due to its newly-discovered physicochemical properties derived from the rich functional groups and  bonds. Herein, we developed a general, simple and kit-like preparation approach for 99mTcI- and Gd-anchored NGO-PEG using a chelator-free strategy. In this strategy, [99mTcI(CO)3(OH2)3]+ (abbreviated to 99mTcI) and GdCl3 were mixed with usNGO-PEG to yield 99mTc- and Gd-usNGO-PEG via the synergistic coordination of N and O atoms from NGO and PEG with 99mTcI and Gd3+ without additional exogenous chelators...
November 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29146741/presence-of-monosodium-urate-crystal-deposition-by-dual-energy-ct-in-patients-with-gout-treated-with-allopurinol
#2
Nicola Dalbeth, Savvas Nicolaou, Scott Baumgartner, Jia Hu, Maple Fung, Hyon K Choi
OBJECTIVE: Dual-energy CT (DECT) detects and quantifies monosodium urate (MSU) crystal deposition with high precision. This DECT study assessed crystal deposition in patients with gout treated with stable-dose allopurinol, and investigated potential clinical determinants for crystal deposition. METHODS: Patients with gout treated with allopurinol ≥300 mg daily for at least 3 months were prospectively recruited from the USA and New Zealand, using monitored enrolment to include approximately 25% patients with palpable tophi and approximately 50% with serum urate (sUA) levels <6...
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29138890/role-of-rapid-kv-switching-dual-energy-ct-in-assessment-of-post-surgical-local-recurrence-of-pancreatic-adenocarcinoma
#3
Anushri Parakh, Manuel Patino, Daniela Muenzel, Avinash Kambadakone, Dushyant V Sahani
PURPOSE: The purpose of this study is to evaluate the performance of material-specific iodine (MS-I) images generated by rapid kV-switching single-source dual-energy computed tomography (rsDECT) for distinguishing post-operative changes from local tumor recurrence in patients on follow-up for pancreatic adenocarcinoma after surgical resection. METHODS: In this IRB-approved HIPPA-compliant study, retrospective review of 51 patients who underwent surgical resection of pancreatic adenocarcinoma was conducted and were followed up using contrast-enhanced rsDECT (Discovery CT 750HD, GE Healthcare, Milwaukee, WI)...
November 14, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29134674/experimental-validation-of-two-dual-energy-ct-methods-for-proton-therapy-using-heterogeneous-tissue-samples
#4
Esther Bär, Arthur Lalonde, Rongxiao Zhang, Kyung-Wook Jee, Kai Yang, Gregory Sharp, Bob Liu, Gary Royle, Hugo Bouchard, Hsiao-Ming Lu
PURPOSE: The purpose of this work is to evaluate the performance of dual-energy CT (DECT) for determining proton stopping power ratios (SPRs) in an experimental environment and to demonstrate its potential advantages over conventional single-energy CT (SECT) in clinical conditions. METHODS: Water equivalent range (WER) measurements of 12 tissue-equivalent plastic materials and 12 fresh animal tissue samples are performed in a 195 MeV broad proton beam using the dose extinction method...
November 14, 2017: Medical Physics
https://www.readbyqxmd.com/read/29132055/benefit-and-clinical-significance-of-retrospectively-obtained-spectral-data-with-a-novel-detector-based-spectral-computed-tomography-initial-experiences-and-results
#5
Prabhakar Rajiah, Rong Rong, Claudia Martinez-Rios, Negin Rassouli, Luis Landeras
OBJECTIVES: To evaluate the benefits and clinical significance of retrospectively generated spectral image-datasets with the novel detector-based Spectral CT (SDCT). METHODS: A total of 118 body CTs from the SDCT prototype were included. Based on the clinical indication, two radiologists were asked if they would have opted for a dual-energy mode/scan if the patient was scanned in one of the other commercially-available dual-energy scanners, which need prospective selection of dual energy mode...
October 31, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29131773/update-on-cardiovascular-applications-of-multienergy-ct
#6
Kevin Kalisz, Sandra Halliburton, Suhny Abbara, Jonathon A Leipsic, Moritz H Albrecht, U Joseph Schoepf, Prabhakar Rajiah
Advances in scanner technology enabling shorter scan times, improvements in spatial and temporal resolution, and more dose-efficient data reconstruction coupled with rapidly growing evidence from clinical trials have established computed tomography (CT) as an important imaging modality in the evaluation of cardiovascular disorders. Multienergy (or spectral or dual-energy) CT is a relatively recent advance in which attenuation data from different energies are used to characterize materials beyond what is possible at conventional CT...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29128993/pancreatic-adenocarcinoma-cross-sectional-imaging-techniques
#7
Naveen M Kulkarni, David M Hough, Parag P Tolat, Erik V Soloff, Avinash R Kambadakone
Pancreatic adenocarcinoma is a common malignancy that has a poor prognosis. Imaging is vital in its detection, staging, and management. Although a variety of imaging techniques are available, MDCT is the preferred imaging modality for staging and assessing the resectability of pancreatic adenocarcinoma. MR also has an important adjunct role, and may be used in addition to CT or as a problem-solving tool. A dedicated pancreatic protocol should be acquired as a biphasic technique optimized for the detection of pancreatic adenocarcinoma and to allow accurate local and distant disease staging...
November 11, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29127998/spectral-computed-tomography-technique-and-applications-for-head-and-neck-cancer
#8
REVIEW
Almudena Pérez-Lara, Reza Forghani
Spectral computed tomography (CT) or dual-energy CT (DECT) is an advanced form of CT with increasing applications in head and neck radiology. This article provides an overview of the DECT technique and reviews current applications for the evaluation of neck pathology, focusing on oncologic applications. Included are an overview of the basic underlying principles and approaches for DECT scan acquisition and material characterization; a discussion of various DECT reconstructions and a brief overview of practical issues pertaining to DECT implementation, including those related to workflow impact of DECT; and a discussion of various applications of DECT for the evaluation of the neck, especially in oncology...
February 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29125334/submillisievert-chest-dual-energy-computed-tomography-a-pilot-study
#9
Rodrigo Canellas, Jeanne B Ackman, Subba R Digumarthy, Melissa Price, Alexi Otrakji, Shaunagh McDermott, Amita Sharma, Mannudeep K Kalra
OBJECTIVE: To assess if diagnostic dual energy CT of the chest can be achieved at submillisievert doses (sub-mSv). METHODS: Our IRB-approved prospective study included 20 patients who were scanned on dual-source MDCT. All patients gave written informed consent for acquisition of additional image series at reduced radiation dose on a dual-source MDCT (80/140kV) within 10 seconds after the standard of care acquisition. Dose reduction was achieved by reducing the quality reference mAs, with combined angular exposure control...
November 10, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29120984/effects-of-different-resistance-training-systems-on-muscular-strength-and-hypertrophy-in-resistance-trained-older-women
#10
Alex S Ribeiro, Andreo F Aguiar, Brad J Schoenfeld, João Pedro Nunes, Edilaine F Cavalcanti, Eduardo L Cadore, Edilson S Cyrino
The purpose of this study was to investigate the effect of resistance training (RT) performed in a pyramid (PR) versus constant (CT) load system on muscular strength and hypertrophy in resistance-trained older women. Thirty-three older women (69.7±5.9 years, 69.1±15.0 kg, 156.6±6.2 cm, and 28.1±5.4 kg.m) were randomized into 2 groups: one that performed RT with a CT load (n = 16) and another group that performed RT in an ascending PR fashion (n = 17). Outcomes included 1 repetition maximum (RM) tests and assessment of skeletal muscle mass estimated by dual energy X-ray absorptiometry...
November 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29119457/dual-energy-computed-tomography-for-the-head
#11
REVIEW
Norihito Naruto, Toshihide Itoh, Kyo Noguchi
Dual energy CT (DECT) is a promising technology that provides better diagnostic accuracy in several brain diseases. DECT can generate various types of CT images from a single acquisition data set at high kV and low kV based on material decomposition algorithms. The two-material decomposition algorithm can separate bone/calcification from iodine accurately. The three-material decomposition algorithm can generate a virtual non-contrast image, which helps to identify conditions such as brain hemorrhage. A virtual monochromatic image has the potential to eliminate metal artifacts by reducing beam-hardening effects...
November 9, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29111386/method-for-determining-the-half-value-layer-in-computed-tomography-scans-using-a-real-time-dosimeter-application-to-dual-source-dual-energy-acquisition
#12
Kosuke Matsubara, Hiroji Nagata, Rena Okubo, Tadanori Takata, Masanao Kobayashi
PURPOSE: We have proposed a method for determining the half-value layers (HVL) in dual-source dual-energy computed tomography (DS-DECT) scans without the need for the X-ray tubes to be fixed. METHODS: A custom-made lead-covered case and an ionizing chamber connected with a multi-function digitizer module (a real-time dosimeter) were used. The chamber was placed in the center of the case, and aluminum or copper filters were placed in front of the aperture. The HVL was measured using aperture widths of 1...
October 27, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/29104864/imaging-therapy-response-of-gastrointestinal-stromal-tumors-gist-with-fdg-pet-ct-and-mri-a-systematic-review
#13
REVIEW
Antonia Dimitrakopoulou-Strauss, Ulrich Ronellenfitsch, Caixia Cheng, Leyun Pan, Christos Sachpekidis, Peter Hohenberger, Thomas Henzler
Purpose: Improvement of the therapeutic approaches in gastrointestinal stromal tumors (GIST) by the introduction of targeted therapies requires appropriate diagnostic tools, which allow sufficient assessment of therapeutic response, including differentiation of true progression from pseudoprogression due to myxoid degeneration or intratumoral hemorrhage. In this literature review the impact and limitations of different imaging modalities used in GIST therapy monitoring are discussed. Methods: PubMed and Cochrane library search were performed using appropriate keywords...
2017: Clinical and Translational Imaging: Reviews in Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29103478/liver-investigations-updating-on-us-technique-and-contrast-enhanced-ultrasound-ceus
#14
REVIEW
Valentina Battaglia, Rosa Cervelli
Over the past few years, the cross sectional imaging techniques (Computed Tomography - CT and Magnetic Resonance - MR) have improved, allowing a more efficient study of focal and diffuse liver diseases. Many papers had been published about the results of a routinely clinical use of the dual source/dual energy CT techniques and the use of hepatobiliary contrast agents in MR liver studies. As a consequence, these new improvements have diverted the attention away from the Ultrasound technique and its technical and conceptual evolutions...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29103468/correlations-between-the-iodine-concentrations-from-dual-energy-computed-tomography-and-molecular-markers-ki-67-and-hif-1%C3%AE-in-rectal-cancer-a-preliminary-study
#15
Shuxuan Fan, Xubin Li, Lei Zheng, Dongzhi Hu, Xiaoyi Ren, Zhaoxiang Ye
PURPOSE: To investigate whether dual energy computed tomography (CT) with iodine quantification is correlated with molecular markers Ki-67and hypoxia-inducible factor 1α (HIF-1α)in rectal cancer (RC). MATERIALS AND METHODS: Eighty patients (43 males and 37 females) diagnosed with rectal cancer got pelvic contrast-enhanced CT scan with dual energy computed tomography before any anticancer treatment. Analyse the normalized iodine concentration (NIC) values and CT values at each energy level (40-140 keV) from the virtual monochromatic image of the primary lesions...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29103097/vertebral-imaging-in-the-diagnosis-of-osteoporosis-a-clinician-s-perspective
#16
REVIEW
Sharon H Chou, Meryl S LeBoff
PURPOSE OF REVIEW: Vertebral fractures are the most common osteoporotic fracture and result in functional decline and excess mortality. Dual-energy x-ray absorptiometry (DXA) is the gold standard for the diagnosis of osteoporosis to identify patients at risk for fragility fractures; however, advances in imaging have expanded the role of computed tomography (CT) and magnetic resonance imaging (MRI) in evaluating bone health. RECENT FINDINGS: The utility of CT and MRI in the assessment of bone density is starting to gain traction, particularly when used opportunistically...
November 4, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/29102938/clinical-impact-of-rest-dual-energy-computed-tomography-myocardial-perfusion-in-patients-with-coronary-artery-disease
#17
Stefan Baumann, Marlon Rutsch, Tobias Becher, Philipp Kryeziu, Holger Haubenreisser, Nils Vogler, Celi Anne Schoenike, Martin Borggrefe, Stefan O Schoenberg, Ibrahim Akin, Thomas Henzler, Dirk Lossnitzer
BACKGROUND/AIM: To evaluate the hypothesis that patients with suspected coronary artery disease (CAD) assessed using rest dual-energy computed tomography-derived myocardial perfusion imaging (DECT-P), could have fewer invasive coronary angiographies (ICA), showing non-obstructive CAD. MATERIALS AND METHODS: Patients who had undergone coronary computed tomography angiography (cCTA), rest DECT-P and ICA were analyzed. RESULTS: We evaluated 51 patients (62...
November 2017: In Vivo
https://www.readbyqxmd.com/read/29097351/dual-energy-ct-in-colorectal-cancers-beyond-the-density-measurements
#18
Sivasubramanian Srinivasan
No abstract text is available yet for this article.
November 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29089820/effect-of-a-novel-intracycle-motion-correction-algorithm-on-dual-energy-spectral-coronary-ct-angiography-a-study-with-pulsating-coronary-artery-phantom-at-high-heart-rates
#19
Yan Xing, Yuan Zhao, Ning Guo, Cun-Xue Pan, Gulina Azati, Yan-Wei Wang, Wen-Ya Liu
OBJECTIVE: Using a pulsating coronary artery phantom at high heart rate settings, we investigated the efficacy of a motion correction algorithm (MCA) to improve the image quality in dual-energy spectral coronary CT angiography (CCTA). MATERIALS AND METHODS: Coronary flow phantoms were scanned at heart rates of 60-100 beats/min at 10-beats/min increments, using dual-energy spectral CT mode. Virtual monochromatic images were reconstructed from 50 to 90 keV at 10-keV increments...
November 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29079119/evaluation-of-stopping-power-prediction-by-dual-and-single-energy-computed-tomography-in-an-anthropomorphic-ground-truth-phantom
#20
Patrick Wohlfahrt, Christian Möhler, Christian Richter, Steffen Greilich
PURPOSE: To determine the accuracy of particle range prediction for proton and heavier ion radiation therapy based on dual-energy computed tomography (DECT) in a realistic inhomogeneous geometry and to compare it with the state-of-the-art clinical approach. METHODS AND MATERIALS: A 3-dimensional ground-truth map of stopping-power ratios (SPRs) was created for an anthropomorphic head phantom by assigning measured SPR values to segmented structures in a high-resolution CT scan...
September 18, 2017: International Journal of Radiation Oncology, Biology, Physics
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