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Measurement based psychiatry

Maarten A van Schijndel, Petra J Caarls, Jeroen D H van Wijngaarden, André I Wierdsma, Jeroen G Lijmer, Annette D Boenink, Witte J G Hoogendijk, Jeroen A van Waarde, Jan J V Busschbach
OBJECTIVE: To define generic quality indicators for general hospital psychiatry from the perspectives of patients, professionals (physicians, nurses, and managers), and payers (health insurance companies). METHODS: Quality variables were identified by reviewing the relevant literature. A working. group consisting of patients', professionals' and payers' representatives was mandated by their respective umbrella organizations. The working group prioritized the quality variables that were identified...
September 25, 2018: General Hospital Psychiatry
Chiaki Kawanishi, Takao Ishii, Naohiro Yonemoto, Mitsuhiko Yamada, Hirokazu Tachikawa, Toshifumi Kishimoto, Noa Tsujii, Satoshi Hashimoto, Toshihiko Kinoshita, Masaru Mimura, Yoshiro Okubo, Kotaro Otsuka, Reiji Yoshimura
INTRODUCTION: Suicide attempt is the most important risk factor for later suicide. A randomised-controlled, multicentre trial of postsuicide attempt case management for the prevention of further suicide attempts in Japan, named ACTION-J, has established effective interventions for prevention of suicide reattempts. The ACTION-J assertive case management intervention programme was adopted by the Japanese Ministry of Health, Labour and Welfare in 2016, when medical fees were revised. This nationwide programme is provided to patients who attempt suicide and who are admitted to emergency departments in Japan...
October 4, 2018: BMJ Open
Corina Aguilar-Raab, Marc N Jarczok, Marco Warth, Martin Stoffel, Friederike Winter, Maria Tieck, Judith Berg, Lobsang Tenzin Negi, Tim Harrison, Thaddeus W W Pace, Beate Ditzen
INTRODUCTION: Positive social interactions (PSIs) and stable relationships can exert substantial benefits on health. However, patients suffering from depression benefit less from these health-promoting effects. Moreover, relationship quality and even partners' health has been found to be negatively affected by depressive symptomatology, which may result in overall impairments in social functioning of a romantic couple. Psychobiological research indicates that these impairments may be accompanied by a maladaptive regulation of the patient's neuroendocrine response to external stressors...
October 4, 2018: BMJ Open
Lisa B Thorell, Hanna Chistiansen, Martin Hammar, Steve Berggren, Eric Zander, Sven Bölte
PURPOSE: The Conners Rating Scales are widely used in research and clinical practice for measuring attention deficit/hyperactivity disorder (ADHD) and associated problem behaviors, but country-specific norms are seldom collected. The current study presents the standardization of the Swedish Conners 3® Rating Scales. In addition, we compared the Swedish norms to those collected in the U.S. and Germany. MATERIAL AND METHODS: The study included altogether 3496 ratings of children and adolescents aged 6-18 years from population-based samples...
September 29, 2018: Nordic Journal of Psychiatry
Sabih Ahmad, Sadiq Hussain
OBJECTIVE: To find out the frequency of psychiatric morbidity in patients reporting to general medical camps in the Hindu Kush and Karakoram ranges of Pakistan. STUDY DESIGN: A cross-sectional study. PLACE AND DURATION OF STUDY: Four different valleys of the region, with the Psychiatry Department, Combined Military Hospital, Gilgit as the base, from August 2015 to December 2016. METHODOLOGY: Consenting adults of either gender, reporting to medical camps for various health related issues were administered Bradford Somatic Inventory 21 (BSI 21) and Self Report Questionnaire (SRQ)...
October 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Tsuyoshi Okamura, Chiaki Ura, Fumiko Miyamae, Mika Sugiyama, Hiroki Inagaki, Edahiro Ayako, Murayama Hiroshi, Keiko Motokawa, Shuichi Awata
AIM: Late-life depression is identified less often by general practitioners than depression in younger adults, but failure to have late-life depression recognized in a primary care setting can have fatal consequences. The aim of the present study was to examine the prevalence of depressed mood and loss of interest, and identify associated factors among community-dwelling older adults in a large-scale study. METHODS: A questionnaire was mailed to all residents (n = 132 005) aged ≥65 years in one Tokyo district...
September 20, 2018: Geriatrics & Gerontology International
A John Rush, Michael E Thase
Specific challenges that profoundly affect the outcome of treatment for depression include 1) patient engagement and retention in care and optimization of treatment adherence, 2) optimization of symptom and side effect control by medication adjustments using measurement-based care procedures, 3) restoration of daily functioning and quality of life, and 4) prevention or at least mitigation of symptomatic relapse or recurrence. According to data from the Sequenced Treatment Alternatives to Relieve Depression study, some 10%-15% of patients will not return for treatment after an initial thorough evaluation visit; an additional 20%-35% will not complete the first acute-phase treatment step, and another 20%-50% will not complete 6 months of continuation treatment...
September 17, 2018: American Journal of Psychiatry
T Steinert, E Flammer
BACKGROUND: The percentage of patients subjected to coercive measures has been proposed as 1 of 10 quality indicators for psychiatric inpatient treatment by the German Association of Psychiatry, Psychotherapy and Psychosomatics (DGPPN). Internationally, there are similar recommendations and corresponding reporting systems. METHODS: The registry of coercive measures of psychiatric hospitals in Baden-Württemberg that was established in 2015, yields the possibility to examine the appropriateness of this indicator, based on raw data of 108,863 cases in 2016...
September 13, 2018: Der Nervenarzt
Massimiliano Murgia, Rosanna Izzo, Alessandra Bettinelli, Chiara Di Maggio, Martina De Angelis, Massimiliano Mangone, Marco Paoloni, Andrea Bernetti, Andrea Torquati, Vincenzo Leuzzi, Valter Santilli
BACKGROUND: The Non-Communicating Children Pain Check List-Revised (NCCPC-R) is a clinical assessment tool used to assess and measure pain in children aged 3 to 18 years, with mental and intellectual disabilities, incapable to speaking. AIM: Aim of our study was to test the validity and reliability of the Italian version of the NCCPC- R in children with cognitive impairment, in order to obtain a valid tool for pain assessment in these children. DESIGN: Prospective observational study...
August 29, 2018: European Journal of Physical and Rehabilitation Medicine
Daniel Di Matteo, Alexa Fine, Kathryn Fotinos, Jonathan Rose, Martin Katzman
BACKGROUND: It has become possible to use data from a patient's mobile phone as an adjunct or alternative to the traditional self-report and interview methods of symptom assessment in psychiatry. Mobile data-based assessment is possible because of the large amounts of diverse information available from a modern mobile phone, including geolocation, screen activity, physical motion, and communication activity. This data may offer much more fine-grained insight into mental state than traditional methods, and so we are motivated to pursue research in this direction...
August 29, 2018: JMIR Mental Health
Larissa Niemeyer, Lucca Schumm, Konstantin Mechler, Christine Jennen-Steinmetz, Ralf W Dittmann, Alexander Häge
OBJECTIVES: Medication nonadherence constitutes a major problem in adolescent psychiatry. Previous studies have identified various factors associated with nonadherent behavior. The aim of this study is to explore adolescents' health beliefs and subjective perceptions relating to psychotropic medication, and to statistically link these to reported medication adherence. METHODS: The findings presented in this study are part of the multicenter SEMA study (Subjective Experience and Medication Adherence in Adolescents with Psychiatric Disorders)...
August 27, 2018: Journal of Child and Adolescent Psychopharmacology
Nathaniel J Williams, Rinad S Beidas
BACKGROUND: Scientists have developed evidence-based interventions that improve the symptoms and functioning of youth with psychiatric disorders; however, these interventions are rarely used in community settings. Eliminating this research-to-practice gap is the purview of implementation science, the discipline devoted to the study of methods to promote the use of evidence-based practices in routine care. METHODS: We review studies that have tested factors associated with implementation in child psychology and psychiatry, explore applications of social science theories to implementation, and conclude with recommendations to advance implementation science through the development and testing of novel, multilevel, causal theories...
August 25, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
J R Kelly, G Clarke, J F Cryan, T G Dinan
The biological mechanisms underlying psychiatric diagnoses are not well defined. Clinical diagnosis based on categorical systems exhibit high levels of heterogeneity and co-morbidity. The Research Domain Criteria (RDoC) attempts to reconceptualize psychiatric disorders into transdiagnostic functional dimensional constructs based on neurobiological measures and observable behaviour. By understanding the underlying neurobiology and pathophysiology of the relevant processes, the RDoC aims to advance biomarker development for disease prediction and treatment response...
June 2018: Irish Journal of Psychological Medicine
Stéphanie Klein Tuente, Stefan Bogaerts, Sarah van IJzendoorn, Wim Veling
BACKGROUND: Many patients residing in forensic psychiatric centers have difficulties regulating their aggression in an adequate manner. Therefore, they are frequently involved in conflicts. Evidenced-based aggression therapies in forensic psychiatry are scarce, and due to the highly secured environment, it is hard to practice real-life provocations. We have developed a Virtual Reality aggression prevention training (VRAPT), providing safe virtual environments, in which patients can practice controlling their aggressive behaviors in an adequate way...
August 6, 2018: BMC Psychiatry
Juan Valdes-Stauber
BACKGROUND: Whereas from a professional point of view, a medical treatment might seem necessary, this treatment might be refused by the patient. In such cases, the patient's ability to determine his will is the key. Any substitutive medical decision is justified by a specific normative framework. OBJECTIVE: The dialectic between a patient's inability to determine his will and the conviction of physicians about the necessity of a medical intervention is reformulated from a medical-anthropological point of view...
July 30, 2018: Fortschritte der Neurologie-Psychiatrie
Charles Alezrah, Marielle Lafont, Roland Bouet, Anne Depaigne-Loth, Cédric Paindavoine, Michel Laurence, Marie-Hélène Rodde-Dunet, Jean-Louis Senon
Over recent years, the psychiatric sector has endeavoured to develop community-based care. Paradoxically, the number of compulsory hospitalisations is increasing. At the same time, the legal framework is evolving and measures relating to the deprivation of liberty in the context of psychiatric care have given rise to extensive guidelines. The work of the French National Health Authority represents, in this context, a certain continuity, with regard to the legal, ethical and social discussions around restriction of liberty practices within psychiatric units...
July 2018: Soins. Psychiatrie
Amruta Shanbhag, Helen Awai, Soham Rej, Alan J Thomas, Klajdi Puka, Akshya Vasudev
OBJECTIVES: The objective of this study was to assess the prevalence of orthostatic hypotension (OH) in a sample of late life depression (LLD) patients and to determine the validity of a standardized questionnaire, the Orthostatic Hypotension Questionnaire (OHQ). Secondarily, we wished to assess variables associated with OH. METHODS: We conducted a cross-sectional study on 82 consecutive geriatric outpatients presenting with LLD. OH was defined as a fall in systolic blood pressure of greater than 20 mm Hg and/or 10 mm Hg on diastolic blood pressure on an orthostatic stress test from sitting to standing...
October 2018: International Journal of Geriatric Psychiatry
Jonathan J Halford, M Brandon Westover, Suzette M LaRoche, Micheal P Macken, Ekrem Kutluay, Jonathan C Edwards, Leonardo Bonilha, Giridhar P Kalamangalam, Kan Ding, Jennifer L Hopp, Amir Arain, Rachael A Dawson, Gabriel U Martz, Bethany J Wolf, Chad G Waters, Brian C Dean
OBJECTIVE: The goal of the study was to measure the performance of academic and private practice (PP) neurologists in detecting interictal epileptiform discharges in routine scalp EEG recordings. METHODS: Thirty-five EEG scorers (EEGers) participated (19 academic and 16 PP) and marked the location of ETs in 200 30-second EEG segments using a web-based EEG annotation system. All participants provided board certification status, years of Epilepsy Fellowship Training (EFT), and years in practice...
September 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
Kai Zhao, Hon-Cheong So
Development of new medications is a lengthy and costly process, and drug repositioning might help to shorten the development cycle. We present a machine learning (ML) workflow to drug discovery or repositioning by predicting indication for a particular disease based on drug expression profiles, with a focus on applications in psychiatry. Drugs that are not originally indicated for the disease but with high predicted probabilities serve as candidates for repurposing. This approach is widely applicable to any chemicals or drugs with expression profiles measured, even if drug targets are unknown...
July 16, 2018: IEEE Journal of Biomedical and Health Informatics
Marge Coahran, Loretta M Hillier, Lisa Van Bussel, Edward Black, Rebekah Churchyard, Iris Gutmanis, Yani Ioannou, Kathleen Michael, Tom Ross, Alex Mihailidis
ABSTRACTHospitalized older adults are at high risk of falling. The HELPER system is a ceiling-mounted fall detection system that sends an alert to a smartphone when a fall is detected. This article describes the performance of the HELPER system, which was pilot tested in a geriatric mental health hospital. The system's accuracy in detecting falls was measured against the hospital records documenting falls. Following the pilot test, nurses were interviewed regarding their perceptions of this technology. In this study, the HELPER system missed one documented fall but detected four falls that were not documented...
September 2018: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
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