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https://www.readbyqxmd.com/read/27928096/extremely-late-recurrence-21-years-after-total-removal-of-immature-teratoma-a-case-report-and-literature-review
#1
Yui Mano, Masayuki Kanamori, Toshihiro Kumabe, Ryuta Saito, Mika Watanabe, Yukihiko Sonoda, Teiji Tominaga
Immature teratoma (IMT) is normally treated by resection and adjuvant therapy. The present unusual case of recurrent germinoma occurred 21 years after total resection of pineal IMT. A 3-year-old boy presented with headache, disturbance of consciousness, and Parinaud's syndrome. Magnetic resonance (MR) imaging revealed a pineal mass lesion, and total resection of the tumor was achieved. The histological diagnosis was mature teratoma. He did not receive further treatment, and did well without recurrence for 20 years...
December 7, 2016: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/27922089/elderly-patients-have-an-altered-gut-brain-axis-regardless-of-the-presence-of-cirrhosis
#2
Jasmohan S Bajaj, Vishwadeep Ahluwalia, Joel L Steinberg, Sarah Hobgood, Peter A Boling, Michael Godschalk, Saima Habib, Melanie B White, Andrew Fagan, Edith A Gavis, Dinesh Ganapathy, Phillip B Hylemon, Karen E Stewart, Raffi Keradman, Eric J Liu, Jessica Wang, Patrick M Gillevet, Masoumeh Sikaroodi, F Gerard Moeller, James B Wade
Cognitive difficulties manifested by the growing elderly population with cirrhosis could be amnestic (memory-related) or non-amnestic (memory-unrelated). The underlying neuro-biological and gut-brain changes are unclear in this population. We aimed to define gut-brain axis alterations in elderly cirrhotics compared to non-cirrhotic individuals based on presence of cirrhosis and on neuropsychological performance. Age-matched outpatients with/without cirrhosis underwent cognitive testing (amnestic/non-amnestic domains), quality of life (HRQOL), multi-modal MRI (fMRI go/no-go task, volumetry and MR spectroscopy), blood (inflammatory cytokines) and stool collection (for microbiota)...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27920873/migratory-stroke-like-lesions-in-a-case-of-adult-onset-mitochondrial-encephalomyopathy-lactic-acidosis-and-stroke-like-episodes-melas-syndrome-and-a-review-of-imaging-findings
#3
Stephen S Cai, Rainer von Coelln, Theresa J Kouo
Imaging findings of adult-onset mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is poorly documented. The authors present a 48-year-old woman with subacute onset of word-finding difficulties and right arm stiffness. Magnetic resonance imaging performed 2 weeks prior revealed left temporal lobe diffusion and fluid-attenuated inversion recovery hyperintensity predominantly involving the cortex. The apparent diffusion coefficient map showed preserved signal in the temporal cortex...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27916988/circulating-scd36-levels-in-patients-with-non-alcoholic-fatty-liver-disease-and-controls
#4
S Heebøll, M K Poulsen, M J Ornstrup, T N Kjær, S B Pedersen, S Nielsen, H Grønbæk, A Handberg
BACKGROUND AND OBJECTIVE: CD36 is implicated in fatty acid uptake in multiple tissues, including hepatocytes and adipocytes. Circulating CD36 (sCD36) is increased in non-alcoholic fatty liver disease (NAFLD).We explored this association further by investigating correlations between sCD36 levels, intrahepatic lipid content and markers of obesity in NAFLD patients and controls. METHODS: 111 NAFLD patients and 33 normal/overweight controls were included. Intrahepatic lipid content was measured by MR spectroscopy; and subgroups of participants had a dual-energy X-ray absorptiometry (n=99), magnetic resonance imaging (n=94, subcutaneous and visceral adipose tissue) and liver biopsy (n=28 NAFLD patients) performed...
December 5, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27898701/assessing-white-matter-microstructure-in-brain-regions-with-different-myelin-architecture-using-mri
#5
Samuel Groeschel, Gisela E Hagberg, Thomas Schultz, Dávid Z Balla, Uwe Klose, Till-Karsten Hauser, Thomas Nägele, Oliver Bieri, Thomas Prasloski, Alex L MacKay, Ingeborg Krägeloh-Mann, Klaus Scheffler
OBJECTIVE: We investigate how known differences in myelin architecture between regions along the cortico-spinal tract and frontal white matter (WM) in 19 healthy adolescents are reflected in several quantitative MRI parameters that have been proposed to non-invasively probe WM microstructure. In a clinically feasible scan time, both conventional imaging sequences as well as microstructural MRI parameters were assessed in order to quantitatively characterise WM regions that are known to differ in the thickness of their myelin sheaths, and in the presence of crossing or parallel fibre organisation...
2016: PloS One
https://www.readbyqxmd.com/read/27891048/metabolic-signatures-of-lung-cancer-in-sputum-and-exhaled-breath-condensate-detected-by-1-h-magnetic-resonance-spectroscopy-a-feasibility-study
#6
Naseer Ahmed, Tedros Bezabeh, Omkar B Ijare, Renelle Myers, Reem Alomran, Michel Aliani, Zoann Nugent, Shantanu Banerji, Julian Kim, Gefei Qing, Zoheir Bshouty
OBJECTIVES: Lung cancer is one of the most lethal cancers. Currently, there are no biomarkers for early detection, monitoring treatment response, and detecting recurrent lung cancer. We undertook this study to determine if (1)H magnetic resonance spectroscopy (MRS) of sputum and exhaled breath condensate (EBC), as a noninvasive tool, can identify metabolic biomarkers of lung cancer. MATERIALS AND METHODS: Sputum and EBC samples were collected from 20 patients, comprising patients with pathologically confirmed non-small cell lung cancer (n = 10) and patients with benign respiratory conditions (n = 10)...
2016: Magnetic Resonance Insights
https://www.readbyqxmd.com/read/27889022/advanced-mr-imaging-in-pediatric-brain-tumors-clinical-applications
#7
REVIEW
Maarten Lequin, Jeroen Hendrikse
Advanced MR imaging techniques, such as spectroscopy, perfusion, diffusion, and functional imaging, have improved the diagnosis of brain tumors in children and also play an important role in defining surgical as well as therapeutic responses in these patients. In addition to the anatomic or structural information gained with conventional MR imaging sequences, advanced MR imaging techniques also provide physiologic information about tumor morphology, metabolism, and hemodynamics. This article reviews the physiology, techniques, and clinical applications of diffusion-weighted and diffusion tensor imaging, MR spectroscopy, perfusion MR imaging, susceptibility-weighted imaging, and functional MR imaging in the setting of neuro-oncology...
February 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/27889021/neuroimaging-of-peptide-based-vaccine-therapy-in-pediatric-brain-tumors-initial-experience
#8
REVIEW
Andre D Furtado, Rafael Ceschin, Stefan Blüml, Gary Mason, Regina I Jakacki, Hideho Okada, Ian F Pollack, Ashok Panigrahy
The potential benefits of peptide-based immunotherapy for pediatric brain tumors are under investigation. Treatment-related heterogeneity has resulted in radiographic challenges, including pseudoprogression. Conventional MR imaging has limitations in assessment of different forms of treatment-related heterogeneity, particularly regarding distinguishing true tumor progression from efficacious treatment responses. Advanced neuroimaging techniques, including diffusion magnetic resonance (MR), perfusion MR, and MR spectroscopy, may add value in the assessment of treatment-related heterogeneity...
February 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/27885531/evolution-of-liver-steatosis-quantified-by-mr-imaging-and-mr-spectroscopy-in-morbidly-obese-patients-undergoing-sleeve-gastrectomy-short-term-outcomes
#9
María Engracia Alsina, Jaime Ruiz-Tovar, Angela Bernabeu
BACKGROUND: Currently, the standard procedure used to evaluate hepatic steatosis is the liver biopsy. This is an invasive practice that presents inherent risks. Increasing evidence suggests that magnetic resonance imaging (MRI) and MR spectroscopy (MRS) may represent an accurate method to determine the hepatic lipid content. The aim of this study was to evaluate the effect of sleeve gastrectomy on liver steatosis, quantified by MRI and MRS. PATIENTS AND METHODS: A prospective observational study of patients undergoing laparoscopic sleeve gastrectomy was performed...
November 24, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27882082/early-identification-of-hypoxic-ischemic-encephalopathy-by-combination-of-magnetic-resonance-mr-imaging-and-proton-mr-spectroscopy
#10
Lili Guo, Dehang Wang, Genji Bo, Hui Zhang, Weijing Tao, Ying Shi
Brain damage following a perinatal hypoxic-ischemic encephalopathy (HIE) can be diagnosed by different techniques. The aim of the present study was to combine magnetic resonance (MR) imaging with proton MR spectroscopy in HIE diagnosis and to evaluate their correlation with outcome. A prospective observational cohort study was performed between February 2012 and February 2013. Consecutive newborns, 24 full-term neonates with HIE (mild to moderate and severe group) and 5 normal neonates, were included. Two sequential MR studies were performed; a conventional MR imaging for observation in T1 weighted image (WI) and T2WI, and proton MR spectroscopy for observation in the left or right basal ganglia and thalamus...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27878065/corticobulbar-tract-involvement-in-neuropsychiatric-systemic-lupus-erythematosus-a-case-report
#11
Ho Kyun Kim, Mun Han, Hui Joong Lee
A 36-year-old woman, diagnosed with systemic lupus erythematosus (SLE), showed bulbar symptoms including impaired memory, slurred speech and swallowing difficulty 7 days before admission. Magnetic resonance imaging (MRI) showed symmetric confluent hyperintensities in the bilateral cerebral white matter on T2 weighted imaging (T2-WI), extended into the genu of the internal capsule and the crus cerebri of the midbrain. MR spectroscopy showed increased choline and decreased N-acetyl aspartate (NAA) peak and positron emission computed tomography (PET CT) showed decreased fluorodeoxyglucose (FDG) uptake on the lateral portion of the frontal lobe, suggesting demyelination of the white matter...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27873353/adaptively-optimized-combination-aoc-of-phased-array-mr-spectroscopy-data-in-the-presence-of-correlated-noise-compared-with-noise-decorrelated-or-whitened-methods
#12
Minjie Wu, Liang Fang, Charles E Ray, Anand Kumar, Shaolin Yang
PURPOSE: A method for adaptively optimized combination (AOC) of MR spectroscopic data from a coil array was recently introduced. The superior performance of the AOC method is evident when compared with the methods that assume uncorrelated noise between coil elements. However, it is unclear whether the AOC method represents the most optimal combination in the presence of correlated noise, when compared with the noise-decorrelated or whitened methods that specifically tackle the correlated noise between coil elements...
November 21, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27871812/effects-of-roux-en-y-gastric-bypass-and-sleeve-gastrectomy-on-bone-mineral-density-and-marrow-adipose-tissue
#13
Miriam A Bredella, Logan B Greenblatt, Alireza Eajazi, Martin Torriani, Elaine W Yu
Bariatric surgery is associated with bone loss but skeletal consequences may differ between Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), the two most commonly performed bariatric procedures. Furthermore, severe weight loss is associated with high marrow adipose tissue (MAT); however, MAT is also increased in visceral adiposity. The purpose of our study was to determine the effects of RYGB and SG on BMD and MAT. We hypothesized that both bariatric procedures would lead to a decrease in BMD and MAT...
November 15, 2016: Bone
https://www.readbyqxmd.com/read/27870506/differential-neurometabolite-alterations-in-brains-of-medication-free-individuals-with-bipolar-disorder-and-those-with-unipolar-depression-a-two-dimensional-proton-magnetic-resonance-spectroscopy-study
#14
Hui Li, Haiyun Xu, Yinnan Zhang, Jitian Guan, Jie Zhang, Chongtao Xu, Zhiwei Shen, Bo Xiao, Chunlian Liang, Kaiyuan Chen, Jinling Zhang, Renhua Wu
OBJECTIVES: Bipolar disorder (BD) is a mental disorder characterized by periods of elevated mood and depression. Many individuals with BD are initially misdiagnosed and treated for unipolar depression (UD). In this study, we report direct comparisons between medication-free individuals with BD and those with UD in terms of the neurometabolites in the anterior cingulate cortex (ACC), medial prefrontal cortex (mPFC), parietal cortex (PC), and posterior cingulate cortex (PCC) of the brain...
November 2016: Bipolar Disorders
https://www.readbyqxmd.com/read/27864577/diagnosing-necrotic-meningioma-a-distinctive-imaging-pattern-in-diffusion-mri-and-mr-spectroscopy
#15
Gal Ben-Arie, Yonatan Serlin, Sebastian Ivens, Mony Benifla, Emanuela Cagnano, Israel Melamed, Vladimir Merkin, Ilan Shelef
The differential diagnosis of necrotic meningiomas includes brain abscess and malignant neoplasms. We report and discuss hereby the work-up of two patients diagnosed with necrotic meningioma using diffusion-weighted imaging, magnetic resonance spectroscopy, resective surgery, and histopathology. The purpose of the present article is to add to the scant literature on the use of advanced imaging modalities in the routine investigation of brain lesions and their utility in arriving at the final diagnosis.
November 18, 2016: Neuroradiology Journal
https://www.readbyqxmd.com/read/27859575/monitoring-acute-metabolic-changes-in-the-liver-and-kidneys-induced-by-fructose-and-glucose-using-hyperpolarized-2-13-c-dihydroxyacetone
#16
Irene Marco-Rius, Cornelius von Morze, Renuka Sriram, Peng Cao, Gene-Yuan Chang, Eugene Milshteyn, Robert A Bok, Michael A Ohliger, David Pearce, John Kurhanewicz, Peder E Z Larson, Daniel B Vigneron, Matthew Merritt
PURPOSE: To investigate acute changes in glucose metabolism in liver and kidneys in vivo after a bolus injection of either fructose or glucose, using hyperpolarized [2-(13) C]dihydroxyacetone. METHODS: Spatially registered, dynamic, multislice MR spectroscopy was acquired for the metabolic products of [2-(13) C]dihydroxyacetone in liver and kidneys. Metabolism was probed in 13 fasted rats at three time points: 0, 70, and 140 min. At 60 min, rats were injected intravenously with fructose (n = 5) or glucose (n = 4) at 0...
November 17, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27858213/prognostic-relevance-of-gemistocytic-grade-ii-astrocytoma-gemistocytic-component-and-mr-imaging-features-compared-to-non-gemistocytic-grade-ii-astrocytoma
#17
Young Jin Heo, Ji Eun Park, Ho Sung Kim, Ji Ye Lee, Soo Jeong Nam, Seung Chai Jung, Choong Gon Choi, Sang Joon Kim
OBJECTIVES: To determine if gemistocytic grade II astrocytoma (GemA) and its MR imaging characteristics are associated with a shorter time-to-progression (TTP) compared with non-gemistocytic grade II astrocytoma (non-GemA). MATERIALS AND METHODS: We enrolled 78 patients who were followed up more than 5 years (29 pathologically proven GemA and 49 non-GemA) during a 10-year period. Contrast-enhanced T1-weighted, diffusion-weighted imaging (DWI), dynamic susceptibility contrast (DSC), and MR spectroscopy (MRS) and clinical data were retrospectively reviewed...
November 17, 2016: European Radiology
https://www.readbyqxmd.com/read/27854056/bioreductive-deposition-of-highly-dispersed-ag-nanoparticles-on-carbon-nanotubes-with-enhanced-catalytic-degradation-for-4-nitrophenol-assisted-by-shewanella-oneidensis-mr-1
#18
Xiaojie Song, Xianyang Shi
Biogenetic nanomaterials research provides insights and valuable implications for the green synthesis of nanomaterials and auxiliary biodegradation behaviors. Ag nanoparticles (Ag NPs) fabricated on multiwalled carbon nanotubes (MWNTs) (Ag/MWNTs nanocomposites) are prepared in situ assisted by Shewanella oneidensis MR-1 (S. oneidensis MR-1) that provide respiratory pathway to transmit electrons. The Ag/MWNTs nanocomposites are characterized by a scanning electron microscopy (SEM), an energy dispersive X-ray (EDX), a transmission electron microscopy (TEM), an X-ray diffraction (XRD), and an X-ray photoelectron spectroscopy (XPS), respectively...
November 16, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27851878/dual-volume-excitation-and-parallel-reconstruction-for-j-difference-edited-mr-spectroscopy
#19
Georg Oeltzschner, Nicolaas A J Puts, Kimberly L Chan, Vincent O Boer, Peter B Barker, Richard A E Edden
PURPOSE: To develop J-difference editing with parallel reconstruction in accelerated multivoxel (PRIAM) for simultaneous measurement in two separate brain regions of γ-aminobutyric acid (GABA) or glutathione. METHODS: PRIAM separates signals from two simultaneously excited voxels using receiver-coil sensitivity profiles. PRIAM was implemented into Mescher-Garwood (MEGA) edited experiments at 3 Tesla (T), and validated by acquiring dual-voxel MEGA-PRIAM (and compared with conventional single-voxel MEGA-PRESS) spectra from a GABA/glutathione phantom, and 11 healthy participants...
November 8, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27851869/intracerebral-synthesis-of-glutamine-from-hyperpolarized-glutamate
#20
Leslie Mazuel, Rolf F Schulte, Aurélie Cladière, Claudine Spéziale, Marie Lagrée, Martin Leremboure, Betty Jean, Franck Durif, Carine Chassain
PURPOSE: Changes in glutamate (Glu) levels occur in a number of neurodegenerative diseases. We proposed the use of (13)C spectroscopy and the highly amplified signal generated by hyperpolarization to achieve spatial and temporal resolutions adequate for in vivo studies of Glu metabolism in the healthy rat brain. Thus, we investigated uptake of hyperpolarized [1(-13C)]Glu after a temporary blood-brain barrier (BBB) disruption protocol and its conversion to glutamine (Gln) in the brain...
November 8, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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