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Induction of labour

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https://www.readbyqxmd.com/read/28076940/cervical-ripening-with-self-administered-iso-sorbide-mononitrate-vaginally-in-uncomplicated-singleton-pregnancies-at-39-weeks-gestation-a-double-blind-randomised-controlled-trial
#1
RANDOMIZED CONTROLLED TRIAL
K Attanayake, M Goonewardene
Introduction: Vaginal iso sorbide mononitrate (ISMN) is effective in pre induction cervical ripening in post dated pregnancies. Objectives: To determine the effectiveness and acceptability of ISMN self-administered vaginally at home, in causing cervical ripening in uncomplicated singleton pregnancies at 39 weeks gestation. Methods: Consecutive women with uncomplicated singleton pregnancies, presenting between 01 October 2013 and 31 March 2014, with a modified Bishop score (MBS) of < 5 at a gestational age (GA) of 273 days to the University Obstetric Unit of Teaching Hospital Mahamodera Galle, were allocated by stratified (primip/multip) block randomisation to self-administer vaginally at home every other day, five doses of 60 mg of sustained release form of ISMN (ISMN-SR); (n = 72, cases), or pyridoxine 10 mgs (n=72, controls), from GA 273 to 282 days...
30, 2016: Ceylon Medical Journal
https://www.readbyqxmd.com/read/28075507/labour-induction-near-term-for-women-aged-35-or-over-an-economic-evaluation
#2
Kate F Walker, Melina Dritsaki, George Bugg, Marion Macpherson, Carol McCormick, Nicky Grace, Chris Wildsmith, Lucy Bradshaw, Gordon Cs Smith, James G Thornton
OBJECTIVE: Induction of labour at 39 weeks for nulliparous women aged 35 years and over may prevent stillbirths and does not increase caesarean births, so it may be popular. But the overall costs and benefits of such a policy have not been compared. DESIGN: A cost-utility analysis alongside a randomised controlled trial (the 35/39 trial). SETTING: Obstetric departments of 38 UK National Health Service hospitals and one UK primary care trust...
January 11, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28068932/women-s-descriptions-of-childbirth-trauma-relating-to-care-provider-actions-and-interactions
#3
Rachel Reed, Rachael Sharman, Christian Inglis
BACKGROUND: Many women experience psychological trauma during birth. A traumatic birth can impact on postnatal mental health and family relationships. It is important to understand how interpersonal factors influence women's experience of trauma in order to inform the development of care that promotes optimal psychosocial outcomes. METHODS: As part of a large mixed methods study, 748 women completed an online survey and answered the question 'describe the birth trauma experience, and what you found traumatising'...
January 10, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28063544/the-prevention-of-early-onset-neonatal-group-b-streptococcal-disease
#4
Deborah Money, Victoria M Allen
OBJECTIVE: To review the evidence in the literature and to provide recommendations on the management of pregnant women in labour for the prevention of early-onset neonatal group B streptococcal disease. The key revisions in this updated guideline include changed recommendations for regimens for antibiotic prophylaxis, susceptibility testing, and management of women with pre-labour rupture of membranes. OUTCOMES: Maternal outcomes evaluated included exposure to antibiotics in pregnancy and labour and complications related to antibiotic use...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28050900/planned-early-birth-versus-expectant-management-waiting-for-prelabour-rupture-of-membranes-at-term-37-weeks-or-more
#5
REVIEW
Philippa Middleton, Emily Shepherd, Vicki Flenady, Rosemary D McBain, Caroline A Crowther
BACKGROUND: Prelabour rupture of membranes (PROM) at term is managed expectantly or by planned early birth. It is not clear if waiting for birth to occur spontaneously is better than intervening, e.g. by inducing labour. OBJECTIVES: The objective of this review is to assess the effects of planned early birth (immediate intervention or intervention within 24 hours) when compared with expectant management (no planned intervention within 24 hours) for women with term PROM on maternal, fetal and neonatal outcomes...
January 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28011129/fast-and-sensitive-in-vivo-studies-under-controlled-environmental-conditions-to-substitute-long-term-field-trials-with-genetically-modified-plants
#6
Patricia Horn, André Schlichting, Christel Baum, Ute Hammesfahr, Sören Thiele-Bruhn, Peter Leinweber, Inge Broer
We introduce an easy, fast and effective method to analyze the influence of genetically modified (GM) plants on soil and model organisms in the laboratory to substitute laborious and time consuming field trials. For the studies described here we focused on two GM plants of the so-called 3rd generation: GM plants producing pharmaceuticals (PMP) and plant made industrials (PMI). Cyanophycin synthetase (cphA) was chosen as model for PMI and Choleratoxin B (CTB) as model for PMP. The model genes are expressed in transgenic roots of composite Vicia hirsuta plants grown in petri dishes for semi-sterile growth or small containers filled with non-sterile soil...
December 21, 2016: Journal of Biotechnology
https://www.readbyqxmd.com/read/28003890/use-of-intracervical-foley-catheter-for-induction-of-labour-in-cases-of-previous-caesarean-section-experience-of-a-single-tertiary-centre-in-oman
#7
Hazel Gonsalves, Nihal Al-Riyami, Tamima Al-Dughaishi, Vaidayanathan Gowri, Mohammed Al-Azri, Ayesha Salahuddin
OBJECTIVES: This study aimed to evaluate rates of success and perinatal complications of labour induction using an intracervical Foley catheter among women with a previous Caesarean delivery at a tertiary centre in Oman. METHODS: This retrospective cohort study included 68 pregnant women with a history of a previous Caesarean section who were admitted for induction via Foley catheter between January 2011 and December 2013 to the Sultan Qaboos University Hospital, Muscat, Oman...
November 2016: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/27974050/neonatal-milk-supplementation-in-lambs-has-persistent-effects-on-growth-and-metabolic-function-that-differ-by-sex-and-gestational-age
#8
Mary J Berry, Anne L Jaquiery, Mark H Oliver, Jane E Harding, Frank H Bloomfield
The perinatal environment has a major influence on long-term health and disease risk. Preterm birth alters early-life environment and is associated with altered metabolic function in adulthood. Whether preterm birth per se or the early nutritional interventions used to support growth in preterm infants underpins this association is unknown. Lambs born preterm, following dexamethasone induction of labour, or spontaneously at term were randomised to receive nutrient supplementation, analogous to the milk fortifier used clinically or water as a control for the first 2 weeks after birth...
December 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27965887/evaluating-acupuncture-and-standard-care-for-pregnant-women-with-back-pain-the-ease-back-pilot-randomised-controlled-trial-isrctn49955124
#9
Annette Bishop, Reuben Ogollah, Bernadette Bartlam, Panos Barlas, Melanie A Holden, Khaled M Ismail, Sue Jowett, Martyn Lewis, Alison Lloyd, Christine Kettle, Jesse Kigozi, Nadine E Foster
BACKGROUND: Low back pain (LBP) and pelvic girdle pain (PGP) during pregnancy are common and often accepted as a 'normal' part of pregnancy. Many women receive little in the way of treatment, and yet pain interferes with sleep, daily activities and work and leads to increasing requests for induction of labour or elective caesarean section. The aim of this study was to assess the feasibility of a full RCT evaluating the benefit of acupuncture for pregnancy-related back pain. METHODS: This study is a single-centre, three-arm pilot RCT in one large maternity unit and associated antenatal and physiotherapy clinics...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27958621/data-comparison-between-pharmacological-induction-of-labour-and-spontaneous-delivery-a-single-centre-experience
#10
Roberta Granese, Gloria Calagna, Alessandro Sollano, Stefania Mondello, Angela Sicilia, Roberta Grasso, Gaspare Cucinella, Onofrio Triolo
OBJECTIVES: To assess the differences in the maternal and fetal outcomes between pharmacological induced and sponta-neous labour in nulliparous women. MATERIAL AND METHODS: Observational cohort study carried out over a period of 2 years. INCLUSION CRITERIA: nulliparous sin-gleton pregnancies, with cephalic fetal presentation, elective labour induction with intra-vaginal prostaglandin E2 (PGE2) gel (Prepidil® 2 mg) at a gestational age of 41 weeks...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27938867/has-perinatal-outcome-improved-after-introduction-of-a-guideline-in-favour-of-routine-induction-and-increased-surveillance-prior-to-42-weeks-of-gestation-a-cross-sectional-population-based-registry-study
#11
Sanne Lausen Wolff, Iben Lorentzen, Agnete Pers Kaltoft, Heidi Schmidt, Monique Mensink Jeppesen, Rikke Damkjær Maimburg
OBJECTIVE: To investigate whether new national guidelines of routine induction of labour and increased surveillance in low risk pregnancies at 41(+2-5) weeks of gestation as an alternative to expectant management until 42(+0) weeks of gestation has improved perinatal outcome. METHODS: A questionnaire-based study regarding local induction practices among all Danish delivery units and a cross-sectional population-based registry study based on data from the Danish Medical Birth Registry (DMBR) in the years 2009-2012...
December 2016: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/27925470/induction-of-labour-vs-spontaneous-vaginal-delivery-in-twin-pregnancy-after-36-weeks-of-gestation
#12
Mariana Vide Tavares, Ana Patrícia Domingues, Filipa Nunes, Margarida Tavares, Etelvina Fonseca, Paulo Moura
Time for delivery and delivery pathway in twin pregnancies are still in great debate. Our study goal was to compare the characteristics of delivery and maternal-foetal outcome in uncomplicated near-term twin pregnancies undergoing labour induction and those with spontaneous labour. We found no statistical differences in patients with twin pregnancies who underwent labour induction and those with spontaneous labour regarding the history of previous caesarean delivery, parity, pregnancy achieved by assisted reproductive techniques (ART), chorionicity and cervical dilation at the admission as well as maternal and neonatal morbidity, and admission to the neonatal intensive care unit...
December 7, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27924657/sonographical-predictive-markers-of-failure-of-induction-of-labour-in-term-pregnancy
#13
Maia Brik, Silvia Mateos, Irene Fernandez-Buhigas, Paloma Garbayo, Gloria Costa, Belen Santacruz
Predictive markers of failure of induction of labour in term pregnancy were evaluated. A prospective study including 245 women attending induction of labour was performed. The inclusion criteria were singleton pregnancies, gestational age 37-42 weeks and the main outcomes were failure of induction, induction to delivery interval and mode of delivery. Women with a longer cervical length prior to induction (CLpi) had a higher rate of failure of induction (30.9 ± 6.8 vs. 23.9 ± 9.3, p < .001)...
December 7, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27922285/a-prospective-randomized-trial-comparing-foley-catheter-oxytocin-and-combination-foley-catheter-oxytocin-for-labour-induction-with-unfavourable-cervix
#14
Nabih I El Khouly
The purpose of this study was to evaluate the effectiveness and safety of transcervical Foley catheter with and without oxytocin versus oxytocin alone for labour induction with unfavourable cervix. This trial enrolled 108 women with singleton pregnancies presented for labour induction with unfavourable cervix. Patients were randomly assigned to receive Foley catheter alone (I), Foley catheter plus oxytocin (II) or oxytocin alone (III). Outcomes were analysed in terms of success of induction, induction delivery interval, route of delivery, dose and duration of oxytocin, and complications...
December 6, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27921388/induction-of-labour-for-fetal-macrosomia-do-we-finally-have-an-answer
#15
E R Norwitz
No abstract text is available yet for this article.
December 5, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27921380/induction-of-labour-for-suspected-macrosomia-at-term-in-non-diabetic-women-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
REVIEW
E R Magro-Malosso, G Saccone, M Chen, R Navathe, M Di Tommaso, V Berghella
BACKGROUND: Several randomized controlled trials (RCTs) compared induction of labour with expectant management in non-diabetic women with suspected fetal macrosomia. OBJECTIVE: To evaluate the effects of labour induction for suspected fetal macrosomia. SEARCH STRATEGY: Literature search in electronic databases. SELECTION CRITERIA: We included all RCTs of suspected fetal macrosomia comparing labour induction with expectant management in term pregnancy...
December 5, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27918616/nitric-oxide-donors-for-cervical-ripening-and-induction-of-labour
#17
REVIEW
Arpita Ghosh, Katherine R Lattey, Anthony J Kelly
BACKGROUND: Sometimes it is necessary to bring on labour artificially because of safety concerns for the mother or baby. This review is one of a series of reviews of methods of labour induction using a standardised protocol. OBJECTIVES: To determine the effects of NO donors (isosorbide mononitrate (ISMN), isosorbide dinitrate (ISDN), nitroglycerin and sodium nitroprusside) for third trimester cervical ripening or induction of labour, in comparison with placebo or no treatment or other treatments from a predefined hierarchy...
5, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27918160/-original-bishop-score-with-modifications
#18
E Hostinská, M Lubušký, K Huml, R Pilka
AIM: To review original Bishop score and its modifications in context of labour induction. DESIGN: A review article. SETTING: Department of Obstetrics and Gynecology, University Hospital, Palacky University, Olomouc. METHOD: Literature review of original Bishop score, simplified Bishop score, as well as modified Bishop scores as predictive factors of successful induction of labour. CONCLUSION: The Bishop score is the most commonly used method to rate the readiness of the cervix for induction of labour...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27856532/management-of-hermansky-pudlak-syndrome-in-pregnancy-and-review-of-literature
#19
Freya Van Avermaete, Joke Muys, Yves Jacquemyn
We report on the obstetric outcome of a woman aged 27 years with Hermansky-Pudlak syndrome (HPS). She underwent a caesarean section after failed induction of labour. Platelet transfusion was administered in a set schedule for 36 hours, starting 2 hours before delivery. The child had good Apgar scores and there were no significant problems of prolonged bleeding during the procedure. 72 hours postpartum, a haematoma developed at the site of the wound, subsequently complicated by a secondary infection for which she received antibiotics...
November 17, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27813240/immediate-delivery-or-expectant-management-in-gestational-diabetes-at-term-the-ginexmal-randomised-controlled-trial
#20
S Alberico, A Erenbourg, M Hod, Y Yogev, E Hadar, F Neri, L Ronfani, G Maso
OBJECTIVE: To evaluate maternal and perinatal outcomes after induction of labour versus expectant management in pregnant women with gestational diabetes at term. DESIGN: Multicentre open-label randomised controlled trial. SETTING: Eight teaching hospitals in Italy, Slovenia, and Israel. SAMPLE: Singleton pregnancy, diagnosed with gestational diabetes by the International Association of Diabetes and Pregnancy Study Groups criteria (IADPSGC), between 38(+0) and 39(+0) weeks of gestation, without other maternal or fetal conditions...
November 4, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
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