keyword
Keywords preoperative hematological eva...

preoperative hematological evaluation

https://read.qxmd.com/read/37778475/is-it-safe-to-continue-aspirin-in-patients-undergoing-percutaneous-nephrolithotomy
#21
JOURNAL ARTICLE
Shree Agrawal-Patel, Harmenjit Brar, Marlie Elia, Juan Fulla, Becky Li, Phornphen Prasanchaimontri, Jianbo Li, Smita De
OBJECTIVE: To evaluate peri-operative outcomes in patients on chronic aspirin therapy undergoing percutaneous nephrolithotomy (PCNL), with and without discontinuation of aspirin. Anti-coagulation and anti-platelet therapy are contraindications for PCNL per American Urological Association guidelines due to bleeding risk. However, there is potentially increased cardiovascular risk with peri-procedural aspirin withdrawal. METHODS: Patients on chronic aspirin undergoing PCNL between January 2014 and May 2019 were retrospectively reviewed and stratified by continued or discontinued aspirin >5 days preoperatively...
January 2024: Urology
https://read.qxmd.com/read/37770192/preoperative-dehydration-predicts-adverse-events-following-anterior-cervical-discectomy-and-fusion
#22
JOURNAL ARTICLE
Abdullah Ghali, Gautham Prabhakar, David Momtaz, Farhan Ahmad, Adam Abbas, Muhammad Shamim, Mahmoud Issa, Varun Bora, Christopher Chaput
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a common procedure for neck arthritis, typically alleviating pain and improving function. Preoperative dehydration has been correlated with postoperative infection, acute renal failure, deep vein thrombosis, and increased hospital length of stay. However, some studies have suggested that preoperative dehydration has a minimal relationship with postoperative outcomes, specifically in arthroplasty and lumbar surgery candidates...
September 28, 2023: International Journal of Spine Surgery
https://read.qxmd.com/read/37729283/diagnosis-of-acute-appendicitis-and-appendicular-perforation-evaluation-of-platelet-indices-and-red-cell-distribution-width-as-emerging-biomarkers
#23
JOURNAL ARTICLE
Chetan Ag, Vijaya Patil
BACKGROUND: Acute appendicitis is a common surgical emergency worldwide. Recent studies on hematological inflammatory markers concerning acute appendicitis have shown variable results. AIMS: The aim of this study was to evaluate pre-operative values of platelet indices such as mean platelet volume (MPV) and platelet distribution width (PDW), and red cell distribution width (RDW) in relation to the diagnosis of acute appendicitis and their efficacy as predictors of appendicular perforation...
2023: Brazilian Archives of Digestive Surgery: ABCD
https://read.qxmd.com/read/37728406/the-prevalence-and-risk-factors-of-coagulopathy-in-pediatric-patients-undergoing-surgery-for-epilepsy
#24
JOURNAL ARTICLE
Renqing Zhu, Qing Wang, Yuanfeng Zhou, Wei Shi, Yi Zhang, Min Wang, Hao Li, Rui Zhao
OBJECTIVE: Hematological consequences of novel antiseizure medications (ASMs) or combined therapies are rarely reported, especially in pediatric patients undergoing surgery for epilepsy. This study aimed to assess the prevalence and risk factors of coagulation dysfunction in this population and evaluate their relationship with intra- and postoperative bleeding. METHODS: Three hundred ninety children who underwent surgery for epilepsy and 104 children without epilepsy who underwent nonepilepsy surgery at the authors' center were included in the study...
August 18, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/37674661/adjuvant-chemotherapy-in-locally-advanced-rectal-cancer-after-neo-adjuvant-concurrent-chemoradiotherapy-and-surgery-a-retrospective-study-in-vietnamese-patients
#25
JOURNAL ARTICLE
Thang Tran, Huy Van Nguyen, Hoa Thi Nguyen, Hung Van Nguyen
BACKGROUND: Advances in preoperative chemoradiotherapy and surgical techniques offered improvements in rates of locoregional recurrence but did not address distant metastasis. Traditionally, adjuvant chemotherapy has been administered with the goal of limiting systemic recurrences. OBJECTIVE: Evaluation of the efficacy and safety of adjuvant chemotherapy in patients with locally advanced rectal cancer after preoperative chemoradiotherapy and surgery. METHODS: From January 2017 to December 2018, 103 patients diagnosed with clinical stage II or III rectal cancer received adjuvant chemotherapy with capecitabine or XELOX regimens after neoadjuvant concurrent chemoradiotherapy and total mesorectal excision...
September 2023: Annals of Medicine and Surgery
https://read.qxmd.com/read/37644670/the-role-of-blood-inflammatory-markers-in-the-preoperative-diagnosis-of-acute-appendicitis
#26
JOURNAL ARTICLE
Alper Adir, Andrei Braester, Perelstein Natalia, Dally Najib, Luiza Akria, Celia Suriu, Barhoum Masad, Waksman Igor
INTRODUCTION: Acute appendicitis (AA) requires a prompt diagnosis. According to postoperative pathological results, a significant number of appendectomies are performed on a normal appendix (NA). The aim of this study is to evaluate the role of preoperative inflammatory markers in supporting and improving the clinical diagnosis of AA, extracting more information from CBC parameters. METHODS: The study is a retrospective one. The histopathological results of operated appendix from 102 patients, who underwent appendectomy for clinically suspected AA, were extracted from the Galilee Medical Center systems...
August 29, 2023: International Journal of Laboratory Hematology
https://read.qxmd.com/read/37633349/preoperative-prediction-and-risk-assessment-of-microvascular-invasion-in-hepatocellular-carcinoma
#27
REVIEW
Jian Li, Xin Su, Xiao Xu, Changchun Zhao, Ang Liu, Liwen Yang, Baoling Song, Hao Song, Zihan Li, Xiangyong Hao
Hepatocellular carcinoma (HCC) is one of the most common and highly lethal tumors worldwide. Microvascular invasion (MVI) is a significant risk factor for recurrence and poor prognosis after surgical resection for HCC patients. Accurately predicting the status of MVI preoperatively is critical for clinicians to select treatment modalities and improve overall survival. However, MVI can only be diagnosed by pathological analysis of postoperative specimens. Currently, numerous indicators in serology (including liquid biopsies) and imaging have been identified to effective in predicting the occurrence of MVI, and the multi-indicator model based on deep learning greatly improves accuracy of prediction...
October 2023: Critical Reviews in Oncology/hematology
https://read.qxmd.com/read/37564949/efficacy-of-ferric-carboxymaltose-in-iron-deficiency-anemia-patients-scheduled-for-pancreaticoduodenectomy
#28
JOURNAL ARTICLE
Jangho Park, Sang-Jae Park, Sung-Sik Han, Hyeong Min Park, Jihye Yu, Boram Park, Young-Woo Kim, Sun-Whe Kim
PURPOSE: Perioperative transfusion is reported to be an independent risk factor not only for postoperative complications but also for early recurrence of periampullary carcinoma after pancreaticoduodenectomy (PD). The purpose of this study was to evaluate the safety and efficacy of ferric carboxymaltose (FCM) in reducing the need for perioperative transfusion in iron deficiency anemia patients scheduled for PD. METHODS: Twenty-two male patients (hemoglobin [Hb] 7 to <13 g/dL) and 18 female patients (Hb 7 to <12 g/dL) were enrolled in the study group and administered FCM 1-3 weeks before PD...
August 2023: Annals of Surgical Treatment and Research
https://read.qxmd.com/read/37530245/prognostic-role-of-metabolic-18f-fdg-pet-ct-parameters-and-hematological-prognostic-indicators-in-patients-with-colorectal-cancer
#29
JOURNAL ARTICLE
Arzu Cengiz, Özlem Yersal, İmran Kurt Ömürlü, Yakup Yürekli
BACKGROUND: The aim of this study is to evaluate the role of preoperative 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) parameters, including maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG), hematologic prognostic indicators in patients with colorectal cancer (CRC) in terms of predicting prognosis. METHODS: One hundred and one patients who had undergone 18F-FDG PET/CT for initial staging were evaluated retrospectively...
2023: Indian Journal of Cancer
https://read.qxmd.com/read/37526408/sarcopenia-in-children-with-wilms-tumor-a-marker-of-undernutrition-which-may-impact-adversely-on-clinical-outcomes
#30
JOURNAL ARTICLE
Wilson E de Oliveira, Mariana S Murra, Leticia M B Tufi, Carlos E B Cavalcante, Marco A de Oliveira, Ricardo F A da Costa, Bianca R Rosa, Roberta Z M da Silva, Rodrigo C Ribeiro, Elena J Ladas, Ronald D Barr
The therapeutic approach to Wilms tumor (WT) is multidisciplinary and leads to significant patient impairment, increasing the risk of nutritional compromise and malnutrition. Children with cancer are vulnerable to sarcopenia which has been recognized as a negative impact of anticancer therapy. Recent studies have highlighted the reduction in the total psoas muscle area (TPMA) to be associated with a poor prognosis in many pediatric diseases, including cancer. This study aims to evaluate changes in the TPMA compartment during the treatment of children with WT...
October 1, 2023: Journal of Pediatric Hematology/oncology
https://read.qxmd.com/read/37526351/techniques-and-complications-of-anesthesia-in-pediatric-radiotherapy-a-retrospective-cohort-study
#31
JOURNAL ARTICLE
Nicolás Villablanca, Nicolás Valls, Roberto González
BACKGROUND: Anesthesia during pediatric external beam radiation therapy poses a challenge, as radiotherapy rooms are not designed for the administration of anesthesia. AIMS: We conducted a retrospective cohort study of children who underwent radiation therapy to describe the anesthetic approach and assess anesthetic-related complications. MATERIALS AND METHODS: Data of all, who underwent radiation therapy under general anesthesia between November 2019 and January 2021, were recorded...
July 14, 2023: Journal of Pediatric Hematology/oncology
https://read.qxmd.com/read/37524101/ferric-derisomaltose-and-tranexamic-acid-combined-or-alone-for-reducing-blood-transfusion-in-patients-with-hip-fracture-the-hifit-trial-a-multicentre-2%C3%A2-%C3%A3-%C3%A2-2-factorial-randomised-double-blind-controlled-trial
#32
RANDOMIZED CONTROLLED TRIAL
Sigismond Lasocki, Xavier Capdevila, Bruno Vielle, Benjamin Bijok, Maria Lahlou-Casulli, Vincent Collange, Nicolas Grillot, Marc Danguy des Deserts, Alexis Duchalais, Bertrand Delannoy, Bertrand Drugeon, Pierre Bouzat, Jean-Stéphane David, Louis Rony, Thibault Loupec, Maxime Léger, Emmanuel Rineau
BACKGROUND: Anaemia and blood transfusion are associated with poor outcomes after hip fracture. We evaluated the efficacy of intravenous iron and tranexamic acid in reducing blood transfusions after hip fracture surgery. METHODS: In this double-blind, randomised, 2 × 2 factorial trial, we recruited adults hospitalised for hip fractures in 12 medical centres in France who had preoperative haemoglobin concentrations between 9·5 and 13·0 g/dL...
September 2023: Lancet Haematology
https://read.qxmd.com/read/37505350/the-importance-of-awaiting-biopsy-results-in-solitary-pathological-proximal-femoral-fractures-do-we-need-to-biopsy-solitary-pathological-fractures
#33
JOURNAL ARTICLE
Floortje G M Verspoor, Gerjon Hannink, Michael Parry, Lee Jeys, Jonathan D Stevenson
BACKGROUND: The optimal surgical treatment for patients presenting with (impending and complete) pathological proximal femoral fractures is predicated on prognosis. Guidelines recommend a preoperative biopsy to exclude sarcomas, however no evidence confirms a benefit. OBJECTIVE: This study aimed to describe the diagnostic accuracy, morbidity and sarcoma incidence of biopsy results in these patients. MATERIAL AND METHODS: All patients (n = 153) presenting with pathological proximal femoral fractures between 2000 and 2019 were retrospectively evaluated...
July 28, 2023: Annals of Surgical Oncology
https://read.qxmd.com/read/37505130/prognostic-value-of-platelet-to-basophil-ratio-pbr-in-patients-with-primary-glioblastoma
#34
JOURNAL ARTICLE
Chao Yang, Jian Xu, Jie Wang, Zhiqiang Li, Qiong Yao
Inflammation is strongly associated with cancers. Our research explored the prognostic role of hematological inflammatory indicators in patients with glioblastoma (GBM). Hundred patients were incorporated finally, and we determined the best cutoff values of these blood markers through X-tile first to perform further survival tests. The prognostic role of peripheral blood cell count and corresponding ratios were assessed using the Kaplan-Meier curve and Cox models to identify variables with independent prognostic significance...
July 28, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37476184/a-preoperative-prediction-of-lymph-node-metastasis-in-early-cervical-squamous-cell-cancer-with-hematologica-based-model
#35
JOURNAL ARTICLE
Qiuyuan Huang, Suyu Li, Xiaoying Chen, Xiaohong Liu, Guangrun Zhou, Liyuan Huang, Xiaoyan Li, Kaiwu Lin, Xiangqin Zheng
Background: This study aimed to construct a preoperative model predicting lymph node metastasis (LNM) in IB1-IIA2 stage cervical squamous cell cancer (CSCC) based on hematological indexes. Merhods: Between February 2011 and February 2022, 463 patients with IB1-IIA2 stage CSCC underwent radical resection. Patients were allocated to either a model-development cohort (n=337) or a validation cohort (n=126). The final model was determined by comparing different methods of variable selection, and then its discrimination and calibration metrics were evaluated...
2023: Journal of Cancer
https://read.qxmd.com/read/37464537/evaluation-of-modified-frailty-index-for-predicting-post-operative-outcomes-after-lower-extremity-free-flap-reconstruction
#36
Mustafa T A Khan, Aashish Rajesh, Lisandro Montorfano, Melinda Lue, Brian Wong Won, Howard T Wang, Rayaad C Hosein
BACKGROUND: Risk stratification for complex procedures such as microsurgical reconstruction of the lower extremities is an important part of preoperative planning and counseling. The aim of this study was to determine the effectiveness of the modified five-item frailty index (5-mFI) score, a validated tool for assessing risk in surgical patients, in predicting postoperative complications after lower extremity (LE) free flap reconstruction. METHODS: A retrospective review of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database was conducted from 2010 to 2020 on patients who underwent LE free-flap reconstruction...
July 18, 2023: Microsurgery
https://read.qxmd.com/read/37437608/high-dose-54%C3%A2-gy-pre-operative-helical-tomotherapy-for-retroperitoneal-liposarcoma-results-of-a-phase-ii-multicenter-study
#37
MULTICENTER STUDY
Paul Sargos, Eberhard Stoeckle, Anne Ducassou, Antoine Giraud, Augustin Mervoyer, Antoine Italiano, Sabrina Albert, Gwenael Ferron, Carine Bellera, Guy Kantor
PURPOSE: To evaluate efficacy and feasibility of high-dose intensity-modulated radiotherapy (RT) with pre-operative helical tomotherapy, delivering 54 Gy/30 fractions in patients with retroperitoneal liposarcomas (RPLS). MATERIALS AND METHODS: Patients with operable, biopsy-proven, RPLS were included in this phase II multicenter study (ClinicalTrials.gov: NCT01841047). The primary objectives were to analyze loco-regional relapse free survival (LRFS), overall survival (OS) and toxicities, graded according to CTCAE V3...
September 2023: Radiotherapy and Oncology
https://read.qxmd.com/read/37403893/plasma-calcium-level-and-c-reactive-protein-albumin-ratio-affect-severe-bleeding-after-coronary-artery-bypass-grafting
#38
JOURNAL ARTICLE
Serdar Badem, Ahmet Yuksel, Ali Onder Kilic, Atilla Pekcolaklar, Nofel Ahmet Binicier, Demir Cetintas, Mehmet Coskun, Haluk Mevre Ozgoz, Yusuf Velioglu
OBJECTIVE: In this study, we aimed to determine whether plasma calcium level and C-reactive protein albumin ratio (CAR) as well as other demographic and hematological markers are related in predicting severe bleeding after coronary artery bypass grafting (CABG). METHODS: A total of 227 adult patients who underwent CABG at our hospital between December 2021 and June 2022 were prospectively studied. Total amount of chest tube drainage was evaluated within the first 24 hours postoperatively or until the patient was re-explored for bleeding...
July 4, 2023: Brazilian Journal of Cardiovascular Surgery
https://read.qxmd.com/read/37402015/preoperative-prognostic-nutritional-index-was-not-predictive-of-short-term-complications-after-laparoscopic-resection-for-rectal-cancer
#39
JOURNAL ARTICLE
Giuseppe Portale, Francesco Cavallin, Chiara Cipollari, Ylenia Spolverato, Diletta Di Miceli, Matteo Zuin, Antonio Mazzeo, Alberto Morabito, Teodoro Sava, Valentino Fiscon
BACKGROUND AND AIM: Prognostic Nutritional Index (PNI) is a useful tool to predict short-term results in patients undergoing surgery for gastrointestinal cancer. Few studies have addressed this issue in colorectal cancer or specifically in rectal cancer. We evaluated the prognostic relevance of preoperative PNI on morbidity of patients undergoing laparoscopic curative resection for rectal cancer (LCRRC). METHODS: PNI data and clinico-pathological characteristics of LCRRC patients (June 2005-December 2020) were evaluated...
July 4, 2023: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/37365597/preoperative-chemoradiation-induced-hematological-toxicity-and-related-vertebral-dosimetry-evaluations-in-patients-with-locally-advanced-gastric-cancer-data-from-a-phase-iii-clinical-trial
#40
RANDOMIZED CONTROLLED TRIAL
Ji-Jin Wang, Han Shao, Li Zhang, Ming Jing, Wen-Jing Xu, Heng-Wen Sun, Zhi-Wei Zhou, Yu-Jing Zhang
BACKGROUND: To explore the hematological toxicity (HT) induced by neoadjuvant chemoradiotherapy (nCRT) compared with neoadjuvant chemotherapy (nCT) and to identify the appropriate vertebral body (VB) dosimetric parameters for predicting HT in patients with locally advanced gastric cancer (GC). METHODS: In the phase III study, 302 patients with GC from an ongoing multi-center randomized clinical trial (NCT01815853) were included. Patients from two major centers were grouped into training and external validation cohorts...
June 9, 2023: Radiation Oncology
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