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https://www.readbyqxmd.com/read/29133066/-qtc-interval-in-the-neonatal-period-in-a-mexican-population-a-pilot-study
#1
Rocio Alejandra Peña-Juárez, Adrián Garcia-Canales, Luis Martin Garrido-García, Cesar Augusto Valerio-Carballo
INTRODUCTION: QT interval prolongation is associated with ventricular arrhythmias and sudden death syndrome. OBJECTIVE: To determine the value of QTc interval in healthy newborns in a general hospital in Jalisco, Mexico, and their outcome during their first months of life. METHODS: The study included healthy newborns from March to November 2016, in the Hospital General of Occidente in Jalisco, Mexico. A 12-lead electrocardiogram was performed at a speed of 25mm/s during the first 48h of life...
November 10, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/29131836/opportunistic-screening-for-atrial-fibrillation-in-a-real-life-setting-in-general-practice-in-denmark-the-atrial-fibrillation-found-on-routine-detection-afford-non-interventional-study
#2
Jonas Hald, Peter Bo Poulsen, Ina Qvist, Lisbeth Holm, Dorte Wedell-Wedellsborg, Lars Dybro, Lars Frost
Atrial fibrillation (AF) is a chronic disease with an incidence increasing steeply by age and affecting more than 11 million patients in Europe and the United States. Diagnosing AF is essential for the prevention of stroke by oral anticoagulation. Opportunistic screening for AF in patients ≥65 years of age is recommended by the European and Danish Societies of Cardiology. The study aim was to examine the detection rate of AF in consecutively screened patients in the primary care setting in Denmark. In an open, non-interventional, cluster, multicenter, cross-sectional, observational study patients ≥65 years of age entering consecutively into general practice clinics were invited to nurse-assisted opportunistic screening for AF...
2017: PloS One
https://www.readbyqxmd.com/read/29131477/a-risk-assessment-score-and-initial-high-sensitivity-troponin-combine-to-identify-low-risk-of-acute-myocardial-infarction-in-the-emergency-department
#3
John W Pickering, Dylan Flaws, Stephen W Smith, Jaimi Greenslade, Louise Cullen, William Parsonage, Edward Carlton, A Mark Richards, Richard Troughton, Christopher Pemberton, Peter M George, Martin P Than
OBJECTIVES: Early discharge of patients with presentations triggering assessment for possible acute coronary syndrome is safe when clinical assessment indicates low-risk, biomarkers are negative, and electrocardiograms (ECGs) are non-ischemic. We hypothesized that the Emergency Department Assessment of Chest Pain Score (EDACS) combined with a single measurement of high-sensitivity cardiac troponin (hs-cTn) could allow early discharge of a clinically meaningful proportion of patients. METHODS: We pooled data from 4 patient cohorts from New Zealand and Australia presenting to an ED with symptoms suggestive of ACS...
November 13, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29131282/prognostic-value-of-daytime-heart-rate-blood-pressure-their-products-and-quotients-in-chronic-heart-failure
#4
Anna Kowalczys, Michał Bohdan, Marcin Gruchała
BACKGROUND: Chronic heart failure (CHF) is an important epidemiological and therapeuthic issue with poor prognosis. The aim of the study was to estimate the prognostic value of daytime heart rate (HR), blood pressure (BP), their products and quotients in patients with CHF. METHODS: The study included 80 stable patients with CHF and reduced left ventricular ejection fraction (LVEF ≤ 35%). Physical examination, laboratory blood tests, electrocardiogram, chest X-ray, echocardiography, 6-minute walk test (6MWT), telemetry monitoring and BP measurements were performed in all participants...
November 13, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29127856/acute-and-long-term-effects-of-fingolimod-on-heart-rhythm-and-heart-rate-variability-in-patients-with-multiple-sclerosis
#5
Ruken Özge Akbulak, Sina C Rosenkranz, Benjamin N Schaeffer, Hans O Pinnschmidt, Stephan Willems, Christoph Heesen, Boris A Hoffmann
BACKGROUND: Fingolimod can lead to increased risk of cardiac events such as bradycardia or atrioventricular (AV) block. OBJECTIVE: Evaluate acute and long-term effects of fingolimod on heart rhythm (HR), heart rate variability (HRV) and development of AV-blocks. METHODS: In 64 patients with relapsing-remitting multiple sclerosis Holter ECG monitoring (HEM) and HRV analysis were performed 24h before, six h during and 72h after initiation of fingolimod...
November 2, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29123213/detecting-abnormality-in-heart-dynamics-from-multifractal-analysis-of-ecg-signals
#6
Snehal M Shekatkar, Yamini Kotriwar, K P Harikrishnan, G Ambika
The characterization of heart dynamics with a view to distinguish abnormal from normal behavior is an interesting topic in clinical sciences. Here we present an analysis of the Electro-cardiogram (ECG) signals from several healthy and unhealthy subjects using the framework of dynamical systems approach to multifractal analysis. Our analysis differs from the conventional nonlinear analysis in that the information contained in the amplitude variations of the signal is being extracted and quantified. The results thus obtained reveal that the attractor underlying the dynamics of the heart has multifractal structure and the variations in the resultant multifractal spectra can clearly separate healthy subjects from unhealthy ones...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29121716/risk-prediction-in-post-infarction-patients-with-moderately-reduced-left-ventricular-ejection-fraction-by-combined-assessment-of-the-sympathetic-and-vagal-cardiac-autonomic-nervous-system
#7
W Hamm, L Stülpnagel, N Vdovin, G Schmidt, K D Rizas, A Bauer
AIM: Most deaths after myocardial infarction (MI) occur in patients with normal or moderately reduced left ventricular ejection fraction (LVEF >35%). Periodic repolarization dynamics (PRD) and deceleration capacity (DC) are novel ECG-based markers related to sympathetic and vagal cardiac autonomic nervous system activity. Here, we test the combination of PRD and DC to predict risk in post-infarction patients with LVEF >35%. METHODS AND RESULTS: We included 823 survivors of acute MI with LVEF >35%, aged ≤80years and in sinus rhythm...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29118976/impact-of-hormonal-modulation-at-proestrus-on-ovarian-responses-and-uterine-gene-expression-of-suckled-anestrous-beef-cows
#8
Manoel Francisco de Sá Filho, Angela Maria Gonella-Diaza, Mariana Sponchiado, Marcio Ferreira Mendanha, Guilherme Pugliesi, Roney Dos Santos Ramos, Sónia Cristina da Silva Andrade, Gustavo Gasparin, Luiz Lehmann Coutinho, Marcelo Demarchi Goissis, Fernando Silveira Mesquita, Pietro Sampaio Baruselli, Mario Binelli
Background: This study evaluated the impact of hormonal modulation at the onset of proestrus on ovarian response and uterine gene expression of beef cows. Methods: A total of 172 anestrous beef cows were assigned to one of four groups according to the treatment with estradiol cypionate (ECP) and/or equine chorionic gonadotropin (eCG) [CON (n = 43), ECP (n = 43), eCG (n = 44) and ECP + eCG (n = 42)]. Results: ECP-treated cows (ECP and ECP + eCG groups) presented greater occurrence of estrus (44...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29115075/unobtrusive-estimation-of-cardiorespiratory-fitness-with-daily-activity-in-healthy-young-men
#9
Joong Woo Ahn, Se Hee Hwang, Chiyul Yoon, Joonnyong Lee, Hee Chan Kim, Hyung Jin Yoon
Despite the importance of cardiorespiratory fitness, no practical method exists to estimate maximal oxygen consumption (VO₂max) without a specific exercise protocol. We developed an estimation model of VO₂max, using maximal activity energy expenditure (aEEmax) as a new feature to represent the level of physical activity. Electrocardiogram (ECG) and acceleration data were recorded for 4 days in 24 healthy young men, and reference VO₂max levels were measured using the maximal exercise test. aEE was calculated using the measured acceleration data and body weight, while heart rate (HR) was extracted from the ECG signal...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29113868/a-case-of-influenza-type-a-myocarditis-that-presents-with-st-elevation-mi-cardiogenic-shock-acute-renal-failure-and-rhabdomyolysis-and-with-rapid-recovery-after-treatment-with-oseltamivir-and-intra-aortic-balloon-pump-support
#10
Eleni Geladari, Vasilios Papademetriou, Hans Moore, David Lu
We present a 59-year-old black male with history of type-1 diabetes and alcohol abuse. Patient became critically ill after a 5-day period of burning throat discomfort. On arrival patient was lethargic, in cardiogenic shock with a blood pressure of 81/47mmHg. Immediate diagnoses included diabetic ketoacidosis, acute renal failure, and possible septic shock. He was intubated, resuscitated with intravenous fluids, maintained on three inotropic agents, and given empiric wide spectrum antibiotics. An ECG showed a new ST elevation MI and an echocardiogram showed severe LV dysfunction...
May 2, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29112591/pharmacokinetics-and-dynamics-of-low-intermediate-and-high-dose-landiolol-and-esmolol-during-long-term-infusion-in-healthy-caucasians
#11
Günther Krumpl, Ivan Ulč, Michaela Trebs, Pavla Kadlecová, Juri Hodisch, Gabriele Maurer, Bernhard Husch
The pharmacokinetics, pharmacodynamics, safety, and tolerability of long-term administration of esmolol and landiolol, a new fast-acting cardioselective β-blocker, were compared for the first time in Caucasian subjects in a prospective clinical trial.Twelve healthy volunteers received landiolol and esmolol by continuous infusion for 24 hr in a randomized crossover study using a dose-escalation regimen. Blood concentrations of drugs and metabolites, heart rate, blood pressure, ECG parameters and tolerability were observed for 30 hrs and compared...
October 31, 2017: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/29108788/peri-procedural-st-segment-resolution-during-primary-percutaneous-coronary-intervention-ppci-for-acute-myocardial-infarction-predictors-and-clinical-consequences
#12
Grigoris V Karamasis, Paul Russhard, Firas Al Janabi, Michael Parker, John R Davies, Thomas R Keeble, Gerald J Clesham
OBJECTIVE: ECG ST segment resolution (STR) has been used to assess myocardial perfusion in STEMI patients undergoing PPCI. However, in most of the studies ECGs recorded at different time points after the actual procedure have been used, limiting the options of therapeutic interventions while the patient is still in the catheterisation laboratory. The aim of this study was to investigate the presence and clinical consequences of intra-procedural STR during PPCI. METHODS: We analysed 12 lead ECGs recorded at the onset and the end of the PPCI procedure, measuring STR in the lead with maximum ST elevation on the initial recording...
October 5, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29103622/a-new-multi-stage-combined-kernel-filtering-approach-for-ecg-noise-removal
#13
Mazhar B Tayel, Ahmed S Eltrass, Abeer I Ammar
Electrocardiogram (ECG) signals are contaminated with different artifacts and noise sources which increase the difficulty in analyzing the ECG signals and obtaining accurate diagnosis of heart diseases. In this paper, a new multi-stage combined adaptive filtering design based on Kernel Recursive Least Squares Tracker (KRLST) and Kernel Recursive Least Squares with Approximate Linear Dependency (ALDKRLS) algorithms is proposed for removing artifacts and noise sources, while preserving the low frequency components and the tiny features of the ECG signal...
October 18, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29100617/relationship-between-frequency-spectrum-of-heart-rate-variability-and-autonomic-nervous-activities-during-sleep-in-newborns
#14
Tsunenori Takatani, Yukihiro Takahashi, Ryota Yoshida, Ryuko Imai, Takao Uchiike, Masaharu Yamazaki, Midori Shima, Toshiya Nishikubo, Yoshito Ikada, Shinichi Fujimoto
INTRODUCTION: We analyzed the frequency spectrum of two neonatal sleep stages, namely active sleep and quiet sleep, and the relationship between these sleep stages and autonomic nervous activity in 74 newborns and 16 adults as a comparison. METHOD: Active and quiet sleep were differentiated by electroencephalogram (EEG) patterns, eye movements, and respiratory wave patterns; autonomic activity was analyzed using the RR interval of simultaneously recorded electrocardiogram (ECG) signals...
October 31, 2017: Brain & Development
https://www.readbyqxmd.com/read/29096909/-assessment-of-mood-disorders-by-passive-data-gathering-the-concept-of-digital-phenotype-versus-psychiatrist-s-professional-culture
#15
A Bourla, F Ferreri, L Ogorzelec, C Guinchard, S Mouchabac
OBJECTIVES: The search for objective clinical signs is a constant practitioners' and researchers' concern in psychiatry. New technologies (embedded sensors, artificial intelligence) give an easier access to untapped information such as passive data (i.e. that do not require patient intervention). The concept of "digital phenotype" is emerging in psychiatry: a psychomotor alteration translated by accelerometer's modifications contrasting with the usual functioning of the subject, or the graphorrhea of patients presenting a manic episode which is replaced by an increase of SMS sent...
October 30, 2017: L'Encéphale
https://www.readbyqxmd.com/read/29095966/systematic-screening-for-atrial-fibrillation-in-a-65-year-old-population-with-risk-factors-for-stroke-data-from-the-akershus-cardiac-examination-1950-study
#16
Trygve Berge, Jon Brynildsen, Hege K Netmangen Larssen, Sophia Onarheim, Gaute R Jenssen, Haakon Ihle-Hansen, Ingrid E Christophersen, Marius Myrstad, Helge Røsjø, Pål Smith, Arnljot Tveit
Aims: To investigate the yield of screening for atrial fibrillation (AF) in a cohort of 65-year-old individuals from the general population with additional risk factors for stroke. Methods and results: We invited participants with additional risk factors for stroke (CHA2DS2-VASc score ≥2 for men or ≥ 3 for women) without previously known AF from a population-based study in Norway to participate in a 2-week screening for AF. Screening was performed by one-lead 'thumb electrocardiography (ECG)' recordings of 30 s twice daily or when the participants experienced symptoms...
October 31, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29093808/sanger-sequencing-as-a-first-line-approach-for-molecular-diagnosis-of-andersen-tawil-syndrome
#17
Armando Totomoch-Serra, Manlio F Marquez, David E Cervantes-Barragán
In 1977, Frederick Sanger developed a new method for DNA sequencing based on the chain termination method, now known as the Sanger sequencing method (SSM).  Recently, massive parallel sequencing, better known as next-generation sequencing (NGS),  is replacing the SSM for detecting mutations in cardiovascular diseases with a genetic background. The present opinion article wants to remark that "targeted" SSM is still effective as a first-line approach for the molecular diagnosis of some specific conditions, as is the case for Andersen-Tawil syndrome (ATS)...
2017: F1000Research
https://www.readbyqxmd.com/read/29093384/a-pilot-study-of-tranilast-for-cardiomyopathy-of-muscular-dystrophy
#18
Tsuyoshi Matsumura, Misa Matsui, Yuko Iwata, Masanori Asakura, Toshio Saito, Harutoshi Fujimura, Saburo Sakoda
Objective Heart failure is currently the most serious complication of muscular dystrophy. The transient receptor potential cation channel, subfamily V, member 2 (TRPV2) is a stretch-sensitive Ca channel. In damaged myocytes or cardiomyocytes, TRPV2 translocates to the cytoplasmic membrane and enhances Ca influx, triggering cell damage. Evidence suggests that the inhibition of TRPV2 may be a new therapeutic target in heart failure. We found that tranilast, which is widely used as an anti-allergic drug, inhibits TRPV2...
November 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29089819/2017-multimodality-appropriate-use-criteria-for-noninvasive-cardiac-imaging-expert-consensus-of-the-asian-society-of-cardiovascular-imaging
#19
REVIEW
Kyongmin Sarah Beck, Jeong A Kim, Yeon Hyeon Choe, Sim Kui Hian, John Hoe, Yoo Jin Hong, Sung Mok Kim, Tae Hoon Kim, Young Jin Kim, Yun Hyeon Kim, Sachio Kuribayashi, Jongmin Lee, Lilian Leong, Tae-Hwan Lim, Bin Lu, Jae Hyung Park, Hajime Sakuma, Dong Hyun Yang, Tan Swee Yaw, Yung-Liang Wan, Zhaoqi Zhang, Shihua Zhao, Hwan Seok Yong
In 2010, the Asian Society of Cardiovascular Imaging (ASCI) provided recommendations for cardiac CT and MRI, and this document reflects an update of the 2010 ASCI appropriate use criteria (AUC). In 2016, the ASCI formed a new working group for revision of AUC for noninvasive cardiac imaging. A major change that we made in this document is the rating of various noninvasive tests (exercise electrocardiogram, echocardiography, positron emission tomography, single-photon emission computed tomography, radionuclide imaging, cardiac magnetic resonance, and cardiac computed tomography/angiography), compared side by side for their applications in various clinical scenarios...
November 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29082854/acute-myocardial-infarction-associated-with-thrombotic-microangiopathy-following-a-hump-nosed-viper-bite-a-case-report
#20
Nipun Lakshitha de Silva, Lalindra Gooneratne, Eranga Wijewickrama
BACKGROUND: Hump-nosed viper bite is the commonest cause of venomous snakebite in Sri Lanka. Despite initially being considered a moderately venomous snake more recent reports have revealed that it could cause significant systemic envenoming leading to coagulopathy and acute kidney injury. However, myocardial infarction was not reported except for a single case, which occurred immediately after the snakebite. CASE PRESENTATION: A 50-year-old previously healthy Sri Lankan woman had a hump-nosed viper bite with no evidence of systemic envenoming during initial hospital stay...
October 30, 2017: Journal of Medical Case Reports
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