Prossy Namuwulya, Shirin Ashraf, Marc Niebel, Alfred Ssekagiri, Phionah Tushabe, Proscovia Kakooza, Lily Tong, Henry Bukenya, Hanna Jerome, Chris Davis, Molly Birungi, Irene Turyahabwe, Arnold Mugaga, James Peter Eliku, Aine Francis, Lucy Nakabazzi, Fred Nsubuga, Edson Katushabe, Annet Kisakye, Immaculate Ampeire, Ann Nanteza, Pontiano Kaleebu, Barnabas Bakamutumaho, Peninah Nsamba, Anne Kazibwe, Ana da Silva Filipe, Robert Tweyongyere, Josephine Bwogi, Emma C Thomson
OBJECTIVES: In this study, we investigated the causes of measles-like illnesses (MLI) in the Uganda national surveillance programme in order to inform diagnostic assay selection and vaccination strategies. METHODS: We used metagenomic next-generation sequencing (M-NGS) on the Illumina platform to identify viruses associated with MLI (defined as fever and rash in the presence of either cough, coryza or conjunctivitis) in patient samples that had tested IgM negative for measles between 2010 and 2019...
April 6, 2024: Journal of Infection