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https://www.readbyqxmd.com/read/28806611/automobile-dependency-as-a-barrier-to-vision-zero-evidence-from-the-states-in-the-usa
#1
Hamed Ahangari, Carol Atkinson-Palombo, Norman W Garrick
With a traffic fatality rate of 10.6 per 100,000 as of 2013-more than triple that in the UK, the Netherlands, and Sweden-the United States has the worst traffic safety performance of all developed countries. Statewide variations are even more pronounced. North Dakota registers more than twice the national average and five times the rate of Massachusetts. We used panel models and annual data from 1997 to 2013 to capture the effect of seven separate sets of factors that influence traffic safety: exposure, travel behavior, socioeconomics, macroeconomics, safety policies, and mitigating factors such as health care...
August 11, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28800694/variability-drivers-and-effects-of-atmospheric-nitrogen-inputs-across-an-urban-area-emerging-patterns-among-human-activities-the-atmosphere-and-soils
#2
Stephen M Decina, Pamela H Templer, Lucy R Hutyra, Conor K Gately, Preeti Rao
Atmospheric deposition of nitrogen (N) is a major input of N to the biosphere and is elevated beyond preindustrial levels throughout many ecosystems. Deposition monitoring networks in the United States generally avoid urban areas in order to capture regional patterns of N deposition, and studies measuring N deposition in cities usually include only one or two urban sites in an urban-rural comparison or as an anchor along an urban-to-rural gradient. Describing patterns and drivers of atmospheric N inputs is crucial for understanding the effects of N deposition; however, little is known about the variability and drivers of atmospheric N inputs or their effects on soil biogeochemistry within urban ecosystems...
August 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28799847/the-willingness-of-people-who-inject-drugs-in-boston-to-use-a-supervised-injection-facility
#3
Casey León, Lena Cardoso, Sarah Mackin, Barry Bock, Jessie M Gaeta
BACKGROUND: In Massachusetts, the number of opioid-related deaths has increased 350% since 2000. In the setting of increasing overdose deaths, one potential intervention is Supervised Injection Facilities (SIFs). This study explores willingness of people who inject drugs in Boston to use a SIF and examines factors associated with willingness. METHODS: A cross-sectional survey of a convenience sample of 237 people who inject drugs and utilize Boston's needle exchange program (NEP)...
August 11, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28799582/american-urological-association-aua-112th-annual-meeting-may-12-16-2017-boston-massachusetts-usa
#4
L Hodgkinson
The American Urological Association (AUA) stands at the forefront of technology development and urological education for urologists and urological healthcare professionals worldwide. The 112th annual meeting brought together a wide range of researchers in the field of urology to access knowledge, up-to-date clinical guidelines and advances in research. The meeting consisted of plenary and moderated poster, podium and video sessions highlighting the latest research and advances in urological medicine. This report highlights some of the presentations on therapeutic developments for a range of urological conditions...
June 2017: Drugs of Today
https://www.readbyqxmd.com/read/28797530/factors-affecting-voice-therapy-completion-in-singers
#5
Michelle Adessa, Tara Stadelman-Cohen, Lauryn Zipse, A J Guarino, James T Heaton
OBJECTIVE: The purpose of this study was to determine (a) which factors may affect singers' completing voice therapy, and (b) develop predictive profiles to capture those singers at risk for dropping out of voice therapy. STUDY DESIGN: A case-control study was conducted comparing singers who completed voice therapy to singers who dropped out of voice therapy. METHODS: Six factors, including age, gender, diagnosis, length of time between laryngology referral and commencement of therapy, type of singer, and referral source were investigated in relation to voice therapy completion using the medical records of 409 singers in the Massachusetts General Hospital Voice Center database...
August 7, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28796462/malformations-surveillance-comparison-between-findings-at-birth-and-age-1-year
#6
Emma G Thomas, Cathleen Higgins, Marie-Noel Westgate, Angela E Lin, Marlene Anderka, Lewis B Holmes
BACKGROUND: Malformations surveillance programs among newborn infants are used to determine the prevalence of congenital anomalies. A comparison in the same group of infants between the malformations detected at birth and those detected at 1 year of age will identify errors in the surveillance process and, also, the abnormalities more likely not to be detected at birth, but later in the first year of life. METHODS: The malformations identified at birth by Brigham and Women's Hospital (BWH) in the years 2000 and 2005 have been compared with the abnormalities detected in the same infants up to age 1 year by the Massachusetts Birth Defects Monitoring Program...
August 10, 2017: Birth defects research
https://www.readbyqxmd.com/read/28795897/living-as-an-lgbtq-adolescent-and-a-parent-s-child-overlapping-or-separate-experiences
#7
Christopher J Mehus, Ryan J Watson, Marla E Eisenberg, Heather L Corliss, Carolyn M Porta
It is well known that parental and community-based support are each related to healthy development in lesbian, gay, bisexual, transgender, queer, and questioning (LGBTQ) youth, but little research has explored the ways these contexts interact and overlap. Through go-along interviews (a method in which participants guide the interviewer around the community) with 66 youth in British Columbia, Massachusetts, and Minnesota, adolescents (aged 14-19 years) reported varying extent of overlap between their LGBTQ experiences and their parent-youth experiences; parents and youth each contributed to the extent of overlap...
May 2017: Journal of Family Nursing
https://www.readbyqxmd.com/read/28789874/genotyping-of-avian-infectious-bronchitis-viruses-in-iran-2015-2017-reveals-domination-of-is-1494-like-virus
#8
Amir Modiri, Arash GhalyanchiLangerodui, Masoud Hashemzadeh, Hossein Hosseini, Vahid Karimi, Ramak Yahyaraeyat, Hamideh Najafi
Avian infectious bronchitis virus (IBV) is causing major economic losses to the poultry industry. The analysis of the S1 gene has been used to determine IBV genotype. The aim of this study was genotyping of IBVs circulating among the Iranian broiler flocks in the period between 2015 to 2017. Trachea samples from 278 broiler flocks were collected from broiler farms in eight provinces of Iran. After Real-time RT-PCR, IBV-positive samples were further characterized based on S1 gene. The results of the Real-time RT-PCR showed that 52...
August 5, 2017: Virus Research
https://www.readbyqxmd.com/read/28783811/social-determinants-of-health-in-managed-care-payment-formulas
#9
Arlene S Ash, Eric O Mick, Randall P Ellis, Catarina I Kiefe, Jeroan J Allison, Melissa A Clark
Importance: Managed care payment formulas commonly allocate more money for medically complex populations, but ignore most social determinants of health (SDH). Objective: To add SDH variables to a diagnosis-based payment formula that allocates funds to managed care plans and accountable care organizations. Design, Setting, and Participants: Using data from MassHealth, the Massachusetts Medicaid and Children's Health Insurance Program, we estimated regression models predicting Medicaid spending using a diagnosis-based and SDH-expanded model, and compared the accuracy of their cost predictions overall and for vulnerable populations...
August 7, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28783808/recrudescence-of-deficits-after-stroke-clinical-and-imaging-phenotype-triggers-and-risk-factors
#10
Mehmet A Topcuoglu, Esen Saka, Scott B Silverman, Lee H Schwamm, Aneesh B Singhal
Importance: Reemergence of previous stroke-related deficits (or poststroke recrudescence [PSR]) is an underrecognized and inadequately characterized phenomenon. Objective: To investigate the clinical features, triggers, and risk factors for PSR. Design, Setting, and Participants: This retrospective study incorporated a crossover cohort study to identify triggers and a case-control study to identify risk factors. The study used the Massachusetts General Hospital Research Patient Data Repository to identify patients for the period January 1, 2000, to November 30, 2015, who had a primary or secondary diagnosis of cerebrovascular disease, who underwent magnetic resonance imaging of the brain at least once, and whose inpatient or outpatient clinician note or discharge summary stated the term recrudescence...
August 7, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28782748/ileostomy-site-approach-for-adhesiolysis-and-laparoscopic-cholecystectomy-in-a-hostile-abdomen-a-novel-technique
#11
Deeplaxmi Purushottam Borle, Nikhil Agrawal, Asit Arora, Senthil Kumar, Tushar Kanti Chattopadhyay
INTRODUCTION: Gallstones are an etiological factor in 23%-54% of patients with acute pancreatitis. A small proportion of these patients will also have intestinal complications requiring necrosectomy with diverting loop ileostomy. Later, these patients require cholecystectomy and ileostomy reversal. Laparoscopic cholecystectomy is fraught with difficulty in these patients due to dense intra-abdominal adhesions, and many surgeons resort to an open approach. We describe a technique which takes advantage of the ileostomy site for initial access...
August 1, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28782106/sirolimus-as-treatment-for-19-patients-with-refractory-cervicofacial-lymphatic-malformation
#12
Julie E Strychowsky, Reza Rahbar, Meghan J O'Hare, Alexandria L Irace, Horacio Padua, Cameron C Trenor
OBJECTIVE: Lymphatic malformations (LMs) are challenging to manage, particularly those involving the cervicofacial region and airway. Traditional therapy is sclerotherapy and/or resection. We aim to establish the emerging therapeutic role of sirolimus. STUDY DESIGN: Institutional review board-approved retrospective review. METHODS: All patients treated for cervicofacial LM with sirolimus at Boston Children's Hospital, Massachusetts, from November 2012 to October 2016 were included...
August 7, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28776576/gnas-mutations-in-primary-mucinous-and-non-mucinous-lung-adenocarcinomas
#13
Lauren L Ritterhouse, Marina Vivero, Mari Mino-Kenudson, Lynette M Sholl, A John Iafrate, Valentina Nardi, Fei Dong
GNAS mutations have been described in mucinous and non-mucinous epithelial neoplasms of the appendix, pancreas, and colon, with hotspot GNAS mutations found in up to two-thirds of pancreatic intraductal papillary mucinous neoplasms. Additionally, many GNAS-mutated tumors have concurrent mutations in the Ras/Raf pathway. The clinicopathologic features of GNAS-mutated lung carcinomas, however, have not yet been characterized. Primary lung carcinomas from Brigham and Women's Hospital (n=1282) or Massachusetts General Hospital (n=1070) were genotyped on a targeted massively parallel sequencing panel of oncogenes and tumor suppressor genes including GNAS...
August 4, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28776490/global-distributions-and-strain-diversity-of-avian-infectious-bronchitis-virus-a-review
#14
Faruku Bande, Siti Suri Arshad, Abdul Rahman Omar, Mohd Hair-Bejo, Aliyu Mahmuda, Venugopal Nair
The poultry industry faces challenge amidst global food security crisis. Infectious bronchitis is one of the most important viral infections that cause huge economic loss to the poultry industry worldwide. The causative agent, infectious bronchitis virus (IBV) is an RNA virus with great ability for mutation and recombination; thus, capable of generating new virus strains that are difficult to control. There are many IBV strains found worldwide, including the Massachusetts, 4/91, D274, and QX-like strains that can be grouped under the classic or variant serotypes...
June 2017: Animal Health Research Reviews
https://www.readbyqxmd.com/read/28774897/generating-a-city-s-first-report-on-bicyclist-safety-lessons-from-the-field
#15
Dahianna S Lopez, David Hemenway
BACKGROUND: For cities aiming to create a useful surveillance system for bicycle injuries, a common challenge is that city crash reporting is scattered, faulty or non-existent. We document some of the lessons we learnt in helping the city of Boston, Massachusetts, USA, do the following: (1) Create a prototype for a comprehensive police crash data set (2) Produce the city's first cyclist safety report, (3) Make crash data available to the public and (4) Generate policy recommendations for both specific roadside improvements and for sustainable changes to the police department's crash reporting database...
August 3, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28771146/a-method-for-incorporating-a-time-dose-response-model-into-a-giardia-lamblia-outbreak
#16
Bidya Prasad, Michael O Ryan, Charles N Haas
Experimental time-to-infection data is a useful, but often underutilized, material for examining the mechanics of in vivo pathogen growth. In this paper, the authors attempt to incorporate a time-dose-response (TDR) equation into a model which predicts the number of ill persons per day in a Giardia lamblia epidemic using data collected from a Pittsfield, Massachusetts outbreak. To this end, dose-response and TDR models were generated for Giardia exposure to beaver and human volunteers, and a maximum likelihood estimation approach was used to ensure that the models provided acceptable fits...
August 2017: Journal of Water and Health
https://www.readbyqxmd.com/read/28769603/two-psammophilic-noctuids-newly-associated-with-beach-plum-prunus-maritima-rosaceae-the-dune-noctuid-sympistis-riparia-and-coastal-heathland-cutworm-abagrotis-benjamini-in-northeastern-north-america-lepidoptera-noctuidae
#17
Paul Z Goldstein, Michael W Nelson
Beach plum, Prunus maritima Marshall, 1785 not Wangenh., 1787 (Rosaceae), currently under development as a potential crop, represents an under-acknowledged host plant for several Lepidoptera that have undergone declines in the northeastern USA. The Coastal Heathland Cutworm, Abagrotis nefascia (Smith, 1908), and the Dune Noctuid, Sympistis riparia (Morrison, 1875), are unrelated species of psammophilic noctuines (Lepidoptera: Noctuidae) regularly encountered on a localized basis in coastal southern New England and New York, and whose precise life history requirements are undocumented...
2017: ZooKeys
https://www.readbyqxmd.com/read/28764807/akt1-low-quiescent-cancer-cells-persist-after-neoadjuvant-chemotherapy-in-triple-negative-breast-cancer
#18
Sheheryar Kabraji, Xavier Solé, Ying Huang, Clyde Bango, Michaela Bowden, Aditya Bardia, Dennis Sgroi, Massimo Loda, Sridhar Ramaswamy
BACKGROUND: Absence of pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) correlates with poor long-term survival in patients with triple negative breast cancer (TNBC). These incomplete treatment responses are likely determined by mechanisms that enable cancer cells to resist being killed. However, the detailed characterization of a drug-resistant cancer cell state in residual TNBC tissue after NACT has remained elusive. AKT1(low) quiescent cancer cells (QCCs) are a quiescent, epigenetically plastic, and chemotherapy-resistant subpopulation initially identified in experimental cancer models...
August 1, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28763472/infectious-bronchitis%C3%A2-corona%C3%A2-virus%C3%A2-establishes-productive-infection-in-avian-macrophages-interfering-with-selected-antimicrobial-functions
#19
Aruna Amarasinghe, Mohamed Sarjoon Abdul-Cader, Sadiya Nazir, Upasama De Silva Senapathi, Frank van der Meer, Susan Catherine Cork, Susantha Gomis, Mohamed Faizal Abdul-Careem
Infectious bronchitis virus (IBV) causes respiratory disease leading to loss of egg and meat production in chickens. Although it is known that macrophage numbers are elevated in the respiratory tract of IBV infected chickens, the role played by macrophages in IBV infection, particularly as a target cell for viral replication, is unknown. In this study, first, we investigated the ability of IBV to establish productive replication in macrophages in lungs and trachea in vivo and in macrophage cell cultures in vitro using two pathogenic IBV strains...
2017: PloS One
https://www.readbyqxmd.com/read/28762078/depression-and-its-correlates-among-brazilian-immigrants-in-massachusetts-usa
#20
Felippe Lazar-Neto, Andressa C Sposato Louzada, Ricardo Faé de Moura, Fernando Morelli Calixto, Marcia C Castro
The goal of this paper is to assess the frequency of depression symptoms among Brazilian immigrants living in Massachusetts, the second largest Brazilian immigrant population in the United States, and to identify correlates of depression. A convenience sample of Brazilian immigrants aged 18 or older residing in Massachusetts was used. Data were collected from December 2013 to March 2014, in the Consulate General of Brazil in Boston and in three religious events, using a structure questionnaire and the Center for Epidemiological Studies Depression Scale (CES-D)...
July 31, 2017: Journal of Immigrant and Minority Health
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