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https://www.readbyqxmd.com/read/30507883/immunoglobulin-g4-related-periorbital-soft-tissue-destruction
#1
Marian Grace Ana-Magadia, Yasuhiro Takahashi, Ma Regina Paula Valencia, Eri Ishikawa, Kunihiro Nishimura, Hirohiko Kakizaki
A study on immunoglobulin G4-related ophthalmic disease (IgG4-ROD) with destructive changes in periorbital soft tissues was presented. The patient was an 89-year-old-man who developed a left-sided orbital lesion involving the globe, lacrimal gland, and extraocular muscles. A diagnosis of definite IgG4-ROD was made based on clinical and histopathologic findings. The patient was started on oral prednisolone, which afforded good response initially. However, when tapering was initiated, full-thickness destruction developed on the lateral half of the lower eyelid margin...
November 30, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/30499528/-intraoperative-prevention-of-dacryocystitis-relapse
#2
E L At'kova, O V Zhukov, N N Krakhovetskiy, V D Yartsev, L V Reznikova
The article reviews the literature devoted to modern intraoperative methods of preventing cicatricial process at the site of dacryostoma after endonasal endoscopic dacryocystorhinostomy. Despite the constant improvement of the surgery technique, complications in the postoperative period still occur. They include the formation of granulation tissue at the sites of dacryostoma, synechiae in the nasal cavity, or narrowing of the dacryostoma, which ultimately leads to a relapse of the disease. The main prevention methods are construction of flaps from the medial wall of the lacrimal sac, from mucosa of the nasal cavity, and intubation of the dacryostoma with the lacrimal implant...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/30481814/dry-eye-after-lasik
#3
Ikuko Toda
Post-LASIK dry eye is the most common postoperative dry eye after ophthalmic surgeries. The clinical signs of post-LASIK dry eye include positive vital staining of the ocular surface, decreased tear breakup time and Schirmer test values, reduced corneal sensitivity, and decreased functional visual acuity. The symptoms and signs usually last for about 1 month after LASIK. A small number of patients continue to experience symptoms more than 1 year postoperatively. It has been suggested that the loss of corneal innervation caused by flap-making is the major cause, affecting the corneal-lacrimal gland, corneal-blinking, and blinking-meibomian gland reflexes, resulting in decreased aqueous and lipid tear secretion and mucin expression...
November 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/30478498/-pathogenesis-and-epidemiology-of-neurotrophic-keratopathy
#4
REVIEW
S Mertsch, J Alder, H S Dua, G Geerling
Neurotrophic keratopathy (NK) is a degenerative corneal disease that is based on an impairment of the corneal innervation. The damage to the sensory innervation, which is delivered through the 1st branch of the trigeminal nerve (ophthalmic nerve), can occur throughout the entire length of the nerve from the nucleus in the brainstem, e.g. caused by brain tumors, to the terminal nerve fibers in the cornea, caused for example by refractive corneal surgery (e. g. LASIK). Due to the loss of the sensory innervation, a reduced lacrimation and a reduction in the secretion of trophic factors occur...
November 26, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/30396885/jones-lacrimal-bypass-tubes-in-children-and-adults
#5
Ilse Mombaerts, Elodie Witters
BACKGROUND/AIMS: Although a Jones tube is considered the mainstay for epiphora in patients with total blockage of the canalicular system, it has been discouraged in children for reasons of inadequate self-care and maintenance. The purpose of this study is to compare the long-term outcome of Jones tube surgery in paediatric versus adult patients. METHODS: Retrospective, interventional case series of a single academic institution. The medical records of all children (≤16 years old) and adults (>16 years old) who underwent conjunctivorhinostomy with placement of a 130° angled extended Jones tube were reviewed...
November 5, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/30364228/laser-assisted-dacryocystorhinostomy-in-nasolacrimal-duct-obstruction-5-year-follow-up
#6
Mustafa Doğan, Anar Alizada, Güliz Fatma Yavaş, Orhan Kemal Kahveci, Osman Bakan
AIM: To evaluate the long-term sucess rate of laser-assisted dacryocystorhinostomy (L-DCR) in patients with nasolacrimal duct obstruction (NDO). METHODS: Forty-one eyes of forty patients aged between 21-85y (mean 56.7y) who underwent L-DCR for the treatment of NDO were included in this retrospective, non-randomized study. The follow-up time was 72mo. Functional sucess was defined as the disappearance of epiphora under normal conditions and the presence of a patent ostium on lacrimal irrigation...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/30360371/congenital-nasolacrimal-duct-obstruction-cnldo-a-review
#7
REVIEW
Aldo Vagge, Lorenzo Ferro Desideri, Paolo Nucci, Massimiliano Serafino, Giuseppe Giannaccare, Andrea Lembo, Carlo Enrico Traverso
Congenital nasolacrimal duct obstruction (CNLDO) is a common condition causing excessive tearing or mucoid discharge from the eyes, due to blockage of the nasolacrimal duct system. Nasolacrimal duct obstruction affects as many as 20% children aged <1 year worldwide and is often resolved without surgery. Available treatment options are conservative therapy, including observation, lacrimal sac massage and antibiotics, and invasive therapy. Observation, combined with conservative options, seems to be the best option in infants aged <1 year...
October 22, 2018: Diseases (Basel)
https://www.readbyqxmd.com/read/30355869/lysosomal-enzymes-and-mannose-6-phosphate-receptors-in-the-lacrimal-drainage-system-evidence-and-its-potential-implications
#8
Mohammad Javed Ali, Ashapogu Venugopal, Kavyashree Sakharayapatna Ranganath, Nadimpalli Siva Kumar
Purpose: To investigate the presence and patterns of lysosomal enzymes and mannose 6-phosophate receptor (MPRs) in human lacrimal drainage system. Methods: The study was performed on healthy lacrimal sacs and nasolacrimal ducts obtained from exenteration samples immediately after surgery and frozen at -80°C for subsequent analysis. Soluble proteins' extract was used for enzyme assays, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (PAGE), native PAGE, activity staining, and western blot analysis...
November 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/30343358/contribution-of-the-plasma-and-lymph-degradome-and-peptidome-to-the-mhc-ligandome
#9
REVIEW
Laura Santambrogio, Hans-Georg Rammensee
Every biological fluid, blood, interstitial fluid and lymph, urine, saliva, lacrimal fluid, nipple aspirate, and spinal fluid, contains a peptidome-degradome derived from the cellular secretome along with byproducts of the metabolic/catabolic activities of each parenchymal organ. Clement et al. (J Proteomics 78:172-187, 2013), Clement et al. (J Biol Chem 291:5576-5595, 2016), Clement et al. (PLoS One 5:e9863, 2010), Clement et al. (Trends Immunol 32:6-11, 2011), Clement et al. (Front Immunol 4:424, 2013), Geho et al...
October 20, 2018: Immunogenetics
https://www.readbyqxmd.com/read/30325843/concurrent-microbial-keratitis-and-nasolacrimal-duct-obstruction-concordance-etiopathogenesis-and-outcome
#10
Arpita Nayak, Sanchita Mitra Basu, Anuria De, Aparajita Mallick, Sujata Das, Suryasnata Rath
PURPOSE: Nasolacrimal duct obstruction (NLDO) is believed to be a risk factor for microbial keratitis (MK). The primary objective of this study was to look at microbiological concordance between corneal scraping and lacrimal sac flora in patients with concurrent MK and NLDO. The secondary objective was to compare microbiological isolates from MK and NLDO, MK alone, NLDO alone, and healthy subjects. METHODS: A prospective comparative study of 146 subjects with standard microbiological analyses was performed between February 2014 and October 2017...
October 5, 2018: Cornea
https://www.readbyqxmd.com/read/30315581/long-term-neurological-morbidity-following-endoscopic-transnasal-resection-of-juvenile-angiofibroma
#11
Davide Mattavelli, Vittorio Rampinelli, Marco Ferrari, Alberto Schreiber, Bruno Guarneri, Piero Nicolai
OBJECTIVES/HYPOTHESIS: Although transnasal endoscopic resection (TER) of juvenile angiofibroma (JA) is unquestionably less invasive than traditional external approaches, several endonasal and neurovascular structures are sacrificed during the procedure. The aim of this study was to evaluate long-term neurological morbidity and related quality of life following TER of JA. STUDY DESIGN: Retrospective cohort study. METHODS: All patients who underwent TER for JA at the Unit of Otorhinolaryngology-Head and Neck Surgery of the University of Brescia from 1994 to 2016 were contacted to know their availability to undergo a battery of tests aimed to assess lacrimal secretion (Schirmer test), impairment of sensitive nerves (electrophysiological threshold test), and impact on quality of life of tearing reduction and sensitivity impairment with the Ocular Surface Disease Index (OSDI) and visual analogue scale (VAS) (0-10), respectively...
October 12, 2018: Laryngoscope
https://www.readbyqxmd.com/read/30311520/successful-chemical-ablation-of-an-intraorbital-cyst-caused-by-an-eyelid-injury-and-iatrogenic-ankyloblepharon-formation-in-a-duck
#12
Shin Ae Park, Harriet Davidson, Kimberly A Thompson, Rachel Policelli Smith, Erica Noland, Dodd Sledge, Jennifer S Thomas, András M Komáromy
CASE DESCRIPTION A client-owned 2-year-old 1.8-kg (4-lb) male pet Rouen duck (Anas platyrhynchos domesticus) was evaluated because of severe swelling around the left eye following traumatic injury to the upper and lower eyelids and 2 associated surgeries that resulted in the removal of the entire upper and lower eyelid margins. CLINICAL FINDINGS At initial evaluation, ankyloblepharon of the left eye was observed, with no upper or lower eyelid margins and a large, round, fluctuant subcutaneous mass over the left orbit...
November 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/30304089/effect-of-superior-blepharoplasty-on-tear-film-objective-evaluation-with-the-keratograph-5m-a-pilot-study
#13
Andreia Soares, Fernando Faria-Correia, Nuno Franqueira, Sara Ribeiro
PURPOSE: To evaluate the effect of superior blepharoplasty on the tear film using the corneal topographer Keratograph 5M. METHODS: A prospective study was performed of 27 eyes of 14 patients with superior dermatochalasis who underwent superior blepharoplasty between May and June 2016. Conservative upper eyelid blepharoplasty was performed by an en bloc resection of anterior lamellar tissue that included skin, subcutaneous tissue, and the orbicularis oculi muscle...
November 2018: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/30299370/preganglionic-parasympathetic-denervation-rabbit-model-for-innervation-studies
#14
Hiroshi Toshida, Chikako Suto
PURPOSE: Tear secretion from the main lacrimal gland (LG) is mainly regulated by parasympathetic nerves. We performed several innervation studies to investigate lacrimation. METHODS: In male rabbits, we performed a retrograde dye-tracing study of LG innervation, evaluated preganglionic parasympathetic denervation, and administered glial cell-derived neurotrophic factor (GDNF) in the surgical area after parasympathetic denervation. RESULTS: Accumulation of fluorescent dye was observed in the pterygopalatine ganglion cells on the same side as the dye injection into the main LG...
November 2018: Cornea
https://www.readbyqxmd.com/read/30234834/nasal-and-lacrimal-sac-histopathology-in-patients-with-systemic-sarcoidosis-undergoing-external-lacrimal-drainage-surgery
#15
Christopher M Stewart, Philip J Luthert, Geoffrey E Rose
PURPOSE: To review the histological findings in the lacrimal sac and nasal mucosa from patients with sarcoidosis undergoing external lacrimal drainage surgery. METHODS: All patients undergoing external dacryocystorhinostomy at Moorfields Eye Hospital with a known history of sarcoidosis had biopsies taken from the lacrimal sac and/or nasal mucosa during surgery. These patients were identified from databases at Moorfields Eye Hospital and the Institute of Ophthalmology, and their clinical notes were reviewed retrospectively for intraoperative findings with a view to identifying common trends...
September 18, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/30228368/randomised-masked-study-of-local-anaesthesia-administered-prior-to-external-dacryocystorhinostomy-under-general-anaesthesia
#16
Richard L Scawn, Matthew J Allen, Geoffrey E Rose, David H Verity
OBJECTIVES: To determine whether administration of local anaesthetic at the site of skin incision during open lacrimal drainage surgery under general anaesthesia alters the total dosage of anaesthetic drugs required during total intravenous anaesthesia (TIVA), and whether it alters postoperative pain and recovery. STUDY DESIGN: Masked comparison of a randomized, two-group interventional study. PATIENTS AND METHODS: Patients undergoing unilateral external dacryocystorhinostomy under total intravenous general anaesthesia were recruited from the lacrimal service at Moorfields Eye Hospital between September 2012 and February 2014...
September 18, 2018: Eye
https://www.readbyqxmd.com/read/30224614/implant-supported-prostheses-in-patient-with-sj%C3%A3-gren-s-syndrome-clinical-report-with-3-year-follow-up
#17
Gentaro Mori, Takafumi Kobayashi, Taichi Ito, Yasutomo Yajima
Sjögren's syndrome (SS), an autoimmune disorder, affects the exocrine glands, including the lacrimal and salivary glands. It is characterized by symptoms of dry eye and dry mouth. As secretion of saliva decreases, patients with SS experience rampant caries, pain in the oral mucosa, inflammation and hardening of the salivary glands, abnormal taste, dysphagia, and loss of teeth earlier than healthy individuals. A removable partial denture is often used as a prosthesis after tooth loss. Compromised salivary lubrication, however, can produce traumatic ulceration of the mucosa, making use of a removable prosthesis in SS patients painful...
2018: Bulletin of Tokyo Dental College
https://www.readbyqxmd.com/read/30217604/lateral-tarsal-strip-versus-lateral-tarsal-strip-with-three-snip-punctoplasty-for-managing-epiphora-in-involutional-ectropion
#18
A Ehrhardt, O Guechi, M Zaidi, M Sot, L Lhuillier, N Houmad, N Ouamara, C Goetz, J-M Perone
PURPOSE: To compare the efficacy of two surgical techniques-lateral tarsal strip (canthoplasty) alone, and lateral tarsal strip with three-snip punctoplasty-in reducing epiphora arising from involutional ectropion with partial punctal stenosis. METHODS: Fourty patients with involutional ectropion and partial stenosis of the lacrimal punctum were randomly allocated to two treatment groups. Group 1 patients received lateral tarsal strip alone with only non-invasive stenting of the punctum, and group 2 patients received tarsal strip plus three-snip punctoplasty...
October 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/30212270/soluble-glycoproteins-of-the-lacrimal-sac-role-in-defense-with-special-reference-to-prolactin-inducible-protein-pip
#19
Mohammad Javed Ali, Ashapogu Venugopal, Kavyashree Sakharayapatna Ranganath, Medicharla V Jagannadham, Siva Kumar Nadimpalli
PURPOSE: Glycoproteins play an important role in human mucosal defenses and immunity-related cell-to-cell interactions. The aim of the present study is to investigate the presence and patterns of lacrimal sac glycoproteins involved in defense mechanisms with a special reference to prolactin-inducible protein (PIP). METHODS: The study was performed on healthy lacrimal sacs obtained from exenteration samples immediately after surgery and frozen at -80 degrees for subsequent analysis...
September 13, 2018: Orbit
https://www.readbyqxmd.com/read/30192193/nervus-intermedius-dysfunctions-after-vestibular-schwannoma-surgery-a-prospective-clinical-study
#20
Hussam Metwali, Katja Kniese, Babak Kardavani, Venelin Gerganov, Madjid Samii
OBJECTIVE The purpose of this prospective study was to evaluate the dysfunction of the nervus intermedius (NI) after vestibular schwannoma (VS) surgery. The authors present a clinically feasible method for this purpose. METHODS In this prospective study, the authors included 30 patients who underwent surgery at the International Neuroscience Institute between May 2014 and February 2017 for resection of VS. The patients' taste sensation was examined using taste strips. Lacrimation was tested using the Schirmer I test...
September 7, 2018: Journal of Neurosurgery
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