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C E Neville, S Montgomery, G Silvestri, A McGowan, E Moore, V Silvestri, C Cardwell, C T McEvoy, A P Maxwell, J V Woodside, G J McKay
BACKGROUND: Retinal vessel abnormalities are associated with cardiovascular disease risk. Widening of retinal venules is associated with increased risk of stroke while narrowing of retinal arterioles independently predicts incident hypertension, coronary heart disease and diabetes. Dietary factors are known to play an important role in cardiovascular health. However, few studies have examined the association between dietary patterns (DPs) and retinal microvascular health. OBJECTIVE: To examine the association between 'a posteriori'-derived DPs and retinal vascular caliber (RVC) in older women with a restricted lifestyle...
2018: Journal of Nutrition, Health & Aging
Fangdi Sun, Alexander Hall, Megan P Tighe, Cheryl L Brunelle, Hoda E Sayegh, Tessa C Gillespie, Kayla M Daniell, Alphonse G Taghian
PURPOSE: Despite increasing emphasis on screening and early intervention for breast cancer-related lymphedema (BCRL), there is marked heterogeneity in diagnostic methodology, including for volumetric measures. This retrospective study compared two volumetric modalities, perometry and simulated circumferential tape measurement (anatomic- and interval-based), for BCRL detection. METHODS: Between 2005 and 2017, 287 female patients with unilateral breast cancer were prospectively screened for BCRL by perometry and the relative volume change (RVC) formula...
July 30, 2018: Breast Cancer Research and Treatment
Laura K Borkenhagen, Kerry A Mallinson, Rick W Tsao, Siaw-Jing Ha, Wei-Honn Lim, Teck-Hock Toh, Benjamin D Anderson, Jane K Fieldhouse, Sarah E Philo, Kuek-Sen Chong, William G Lindsley, Alejandro Ramirez, James F Lowe, Kristen K Coleman, Gregory C Gray
BACKGROUND: The large livestock operations and dense human population of Southeast Asia are considered a hot-spot for emerging viruses. OBJECTIVES: To determine if the pathogens adenovirus (ADV), coronavirus (CoV), encephalomyocarditis virus (EMCV), enterovirus (EV), influenza A-D (IAV, IBV, ICV, and IDV), porcine circovirus 2 (PCV2), and porcine rotaviruses A and C (RVA and RVC), are aerosolized at the animal-interface, and if humans working in these environments are carrying these viruses in their nasal airways...
2018: PloS One
Rowena Alves Coelho, Fábio Brito-Santos, Maria Helena Galdino Figueiredo-Carvalho, Juliana Vitoria Dos Santos Silva, Maria Clara Gutierrez-Galhardo, Antonio Carlos Francesconi do Valle, Rosely Maria Zancopé-Oliveira, Luciana Trilles, Wieland Meyer, Dayvison Francis Saraiva Freitas, Rodrigo Almeida-Paes
BACKGROUND: Chromoblastomycosis (CBM) is a difficult-to-treat chronic subcutaneous mycosis. In Brazil, the main agent of this disease is Fonsecaea pedrosoi, which is phenotypically very similar to other Fonsecaea species, differing only genetically. The correct species identification is relevant since different species may differ in their epidemiologic aspects, clinical presentation, and treatment response. METHODOLOGY/PRINCIPAL FINDINGS: Partial sequencing of the internal transcribed spacer (ITS) was used to identify twenty clinical isolates of Fonsecaea spp...
July 2018: PLoS Neglected Tropical Diseases
Ali Aldalbahi, Mostafizur Rahaman, Mohammed Almoiqli, Abdelrazig Hamedelniel, Abdulaziz Alrehaili
Acid-functionalized single-walled carbon nanotube (a-SWCNT)-coated reticulated vitreous carbon (RVC) composite electrodes have been prepared and the use of these electrodes in capacitive deionization (CDI) cells for water desalination has been the focus of this study. The performance of these electrodes was tested based on the applied voltage, flow rate, bias potential and a-SWCNT loadings, and then evaluated by electrosorption dynamics. The effect of the feed stream directly through the electrodes, between the electrodes, and the distance between the electrodes in the CDI system on the performance of the electrodes has been investigated...
July 13, 2018: Nanomaterials
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June 16, 2018: Veterinary Record
Elizabeth Armitage-Chan, Stephen A May
Professional studies teaching in medical and veterinary education is undergoing a period of change. Traditional approaches, aiming to teach students professional values and behaviors, are being enhanced by curricula designed to support students' professional identity formation. This development offers the potential for improving student engagement and graduates' mental well-being. The veterinary professional identity associated with emotional resilience and success in practice incorporates complexity in professional decision making and the importance of context on behaviors and actions...
June 13, 2018: Journal of Veterinary Medical Education
Diana Isela Sanchez-Alvarado, Javier Guzmán-Pantoja, Ulises Páramo-García, Alfredo Maciel-Cerda, Reinaldo David Martínez-Orozco, Ricardo Vera-Graziano
In this work, chitosan (CS)/poly (vinyl alcohol) (PVA) nanofibers were prepared by using the electrospinning method. Different CS concentrations (0.5, 1, 2, and 3 wt %), maintaining the PVA concentration at 8 wt %, were tested. Likewise, the studied electrospinning experimental parameters were: syringe/collector distance, solution flow and voltage. Subsequently, the electrospun fibers were collected on a reticulated vitreous carbon (RVC) support for 0.25, 0.5, 1, 1.5, and 2 h. The morphology and diameter of the CS/PVA nanofibers were characterized by scanning electron microscopy (SEM), finding diameters in the order of 132 and 212 nm; the best results (uniform fibers) were obtained from the solution with 2 wt % of chitosan and a voltage, distance, and flow rate of 16 kV, 20 cm, and 0...
June 9, 2018: International Journal of Molecular Sciences
D Zhang, Y Guan, L Fan, Y Xia, S Y Liu
Objective: To quantify emphysema and air trapping at inspiratory and expiratory phase multi-slice spiral CT(MSCT) scanning in smokers without respiratory symptoms, and analyze the correlation between the CT quantifiable parameters and lung function parameters. Methods: A total of 72 smokers, who underwent medical examinations from September 2013 to September 2016 in Changzheng Hospital were enrolled in this research and were divided into two groups: 24 smokers with COPD and 48 smokers without COPD.Besides, thirty-nine non-smokers with normal pulmonary function were enrolled as the controls...
May 22, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Yiming Mo, Klavs F Jensen
Electroorganic chemistry has emerged as an environmentally benign tool for synthetic chemists to achieve efficient transformations that are challenging with traditional reagent-based methods. Continuous flow chemistry brings pharmaceutical industry numerous advantages, but implementing electroorganic synthesis in flow is challenging, especially for electroorganic reactions with coupled electrode reactions and slow chemical reactions. We present a continuous electrolysis system engineered for N-hydroxyphthalimide (NHPI) mediated electrochemical aerobic oxidation of benzylic C-H bonds...
May 24, 2018: Chemistry: a European Journal
Jaime Onofre, Katrien Faes, Prashant Kadam, Elena Vicini, Ans M M van Pelt, Ellen Goossens
RESEARCH QUESTION: From a clinical perspective, which parameters grant optimal cryopreservation of mouse testicular cell suspensions? DESIGN: We studied the effect of different cryopreservation rates, the addition of sugars, different vessels and the addition of an apoptotic inhibitor on the efficiency of testicular cell suspension cryopreservation. After thawing and warming, testicular cell suspensions were transplanted to recipient mice for further functional assay...
July 2018: Reproductive Biomedicine Online
Supansa Tuanthap, Cherdpong Phupolphan, Supol Luengyosluechakul, Ausanee Duang-In, Apiradee Theamboonlers, Suphot Wattanaphansak, Sompong Vongpunsawad, Alongkorn Amonsin, Yong Poovorawan
Swine are economically important food animals, but highly contagious porcine epidemic diarrhea virus (PEDV) and rotavirus can afflict pig herds and contribute significantly to piglet morbidity and mortality. While there have been studies on rotavirus group A (RVA) in Thailand, reports of rotavirus group C (RVC) are limited. Here, we aimed to identify the prevalence of RVC circulating on Thai commercial swine farms. We analyzed 769 feces and intestine mucosal contents of pigs affected with diarrhea between 2011 and 2016 using RT-PCR specific for the PEDV spike (S), rotavirus glycoprotein (G) VP7, and protease-sensitive protein (P) VP4 genes...
2018: PeerJ
Reham H Tammam, Ahmed H Touny, Mahmoud M Saleh
Reticulated vitreous carbon (RVC), a high surface area electrode (40 cm2 /cm3 ), has been modified with nickel oxide nanoparticles (nano-NiO x ) and used for electrochemical oxidation of urea from alkaline solution. For the cyclic voltammetry measurements, the used dimensions are 0.8 cm × 0.8 cm × 0.3 cm. The purpose was to offer high specific surface area using a porous open network structure to accelerate the electrochemical conversion. NiO x nanoparticles have been synthesized via an electrochemical route at some experimental conditions...
May 8, 2018: Environmental Science and Pollution Research International
Mark Fox, Damer Blake, Dennis Jacobs
Over the past four decades, there has been an exponential increase in veterinary parasitology knowledge, coinciding with the advent of molecular biology in research. Therefore, it is unrealistic for teachers to expect students to graduate with an encyclopaedic knowledge of the subject. As a result, a new curriculum was introduced at The Royal Veterinary College (University of London) in 2007, designed to meet the needs of our new graduates, i.e. RCVS Day-One Competences. The aims of this curriculum are, inter alia, to ensure that new graduates have an up-to-date body of core knowledge and are able to apply such knowledge and newly-acquired information to scientific and clinical problem-solving...
April 30, 2018: Veterinary Parasitology
Xiaoman Sun, Lihong Wang, Jianxun Qi, Dandi Li, Mengxuan Wang, Xin Cong, Ruchao Peng, Wengang Chai, Qing Zhang, Hong Wang, Hongling Wen, George F Gao, Ming Tan, Zhaojun Duan
Group/species C rotaviruses (RVCs) have been identified as important pathogens of acute gastroenteritis (AGE) in children, family-based outbreaks, as well as animal infections. However, little is known regarding their host-specific interaction, infection, and pathogenesis. In this study, we performed serial studies to characterize the function and structural features of a human G4P[2] RVC VP8* that is responsible for the host receptor interaction. Glycan microarrays demonstrated that the human RVC VP8* recognizes type A histo-blood group antigens (HBGAs), which was confirmed by synthetic glycan-/saliva-based binding assays and hemagglutination of red blood cells, establishing a paradigm of RVC VP8*-glycan interactions...
June 1, 2018: Journal of Virology
Mahmoud A Alomari, Hanan Khalil, Omar F Khabour, Karem H Alzoubi, Esraa H Dersieh
Brain-derived neurotrophic factor (BDNF) has been linked to cardiovascular health and function, however, the exact role is yet to be understood. The current study examined the relationship of circulatory BDNF with vascular function in Parkinson's disease (PD). ELISA was used to determine plasma BDNF in PD patients and healthy control (CT). Additionally, forearm resting blood flow (RBf), vascular resistance (RVr), venous capacitance (RVc), and venous outflow (RVo) as well as post occlusion blood flow (OcBf), vascular resistance (OcVr), venous capacitance (OcVc), and venous outflow (OcVo) were obtained using strain-gauge plethysmography...
May 2018: Experimental Aging Research
Tzong-Ming Shieh, Chi-Yuan Chen, Chuen Hsueh, Cheng-Chia Yu, Chin-Chuan Chen, Tong-Hong Wang
The quality of biological samples greatly affects the accuracy of scientific results. However, RNA in cryopreserved tissues gradually degrades during storage, leading to errors in the results of subsequent experiments. A suitable sample preservative solution can prolong storage and enhance the research value of samples. Here, we developed a sample preservative solution using the properties of the ribonucleoside vanadyl complex (RVC) and compared its effects on RNA and DNA quality, protein activity, and tissue morphology with the commercially available and widely used RNAlater® Stabilization Solution...
2018: PloS One
Blenda Ramírez-Pereda, Alberto Álvarez-Gallegos, Jesús Gabriel Rangel-Peraza, Yaneth A Bustos-Terrones
In this study, a micro-scale parallel plate reactor was built to electrochemically generate hydrogen peroxide (H2 O2 ) and to develop the Fenton reaction in situ, for the treatment of toxic organic pollutants. Two types of carbon materials were compared and used as cathodes: unidirectional carbon fiber (CF) and reticulated vitreous carbon (RVC). As anode, a stainless steel mesh was used. The results of H2 O2 were experimentally compared by means of electrogeneration process. RVC cathode with dimensions of 2...
May 1, 2018: Journal of Environmental Management
Rosana P Rota, Carlos A Palacios, C Facundo Temprana, Marcelo H Argüelles, Marcelo G Mandile, Nora Mattion, Andrea S Laimbacher, Cornell Fraefel, Alejandro A Castello, Graciela Glikmann
Group C Rotavirus (RVC) has been associated globally with sporadic outbreaks of gastroenteritis in children and adults. RVC also infects animals, and interspecies transmission has been reported as well as its zoonotic potential. Considering its genetic diversity and the absence of effective vaccines, it is important and necessary to develop new generation vaccines against RVC for both humans and animals. The aim of the present study was to develop and characterize an HSV-1-based amplicon vector expressing a human RVC-VP6 protein and evaluate the humoral immune response induced after immunizing BALB/c mice...
June 2018: Journal of Virological Methods
Sudipta Bhat, Jobin Jose Kattoor, Yashpal Singh Malik, Shubhankar Sircar, Pallavi Deol, Vinita Rawat, Ritu Rakholia, Souvik Ghosh, Anastasia N Vlasova, Touil Nadia, Kuldeep Dhama, Nobumichi Kobayashi
All over the world, children and adults are severely affected by acute gastroenteritis, caused by one of the emerging enteric pathogens, rotavirus C (RVC). At present, no extensive surveillance program is running for RVC in India, and its prevalence is largely unknown except cases of local outbreaks. Here, we intended to detect the presence of RVC in diarrheic children visiting or admitted to hospitals in Haldwani (state of Uttarakhand, India), a city located in the foothills of the Himalayas. During 2010-2013, we screened 119 samples for RVC by an RVC VP6 gene-specific RT-PCR...
February 17, 2018: Pathogens
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