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Precise nutrition

Rocio Barragán, Oscar Coltell, Olga Portolés, Eva M Asensio, José V Sorlí, Carolina Ortega-Azorín, José I González, Carmen Sáiz, Rebeca Fernández-Carrión, Jose M Ordovas, Dolores Corella
There is growing interest in relating taste perception to diet and healthy aging. However, there is still limited information on the influence of age, sex and genetics on taste acuity as well as on the relationship between taste perception and taste preferences. We have analysed the influence of age on the intensity rating of the five basic tastes: sweet, salty, bitter, sour and umami (separately and jointly in a "total taste score") and their modulation by sex and genetics in a relatively healthy population (men and women) aged 18⁻80 years ( n = 1020 Caucasian European participants)...
October 18, 2018: Nutrients
Cristina González-Díaz, Diana Gil-González, Carlos Álvarez-Dardet
This study aims at understanding how scientific evidence to substantiate nutrition and health claims in food commercial communication is regulated in Europe and the USA. A literature review was performed on the scientific evidence required by the European Food Safety Authority and the US Food and Drug Administration to substantiate food nutrition and health claims. Studies published in Scopus, Medline, Scirus, and Google Scholar from 2007 to 2012 were reviewed as well as documents released by both agencies...
October 19, 2018: Journal of Food Science
Wubet Worku Takele, Mekuriaw Alemayehu, Terefe Derso, Amare Tariku
OBJECTIVE: This study was aimed at determining the magnitude of prenatal iodine deficiency and its determinants among women attending antenatal care clinic at the University of Gondar Specialized Referral Hospital, Northwest Ethiopia. A cross-sectional study was conducted from March 13 to April 25/2017. Precisely, 378 pregnant women were included in the study selected via systematic random sampling technique. Urinary Iodine concentration was determined through spectrophotometer using Sandell-Kolthoff reaction...
October 17, 2018: BMC Research Notes
Dimosthenis A Sarigiannis, Spyros P Karakitsios
BACKGROUND: this paper is based upon work from COST Action ICSHNet. Assessment of the health impacts related to industrially contaminated sites (ICSs) is a major scientific challenge with multiple societal implications. Most studies related to associations between ICSs and public health do not provide established mechanistic links between environmental exposure and disease burden, potentially resulting in suboptimal risk management measures. OBJECTIVES: to assess the potential of the exposome paradigm to overhaul ICS risk assessment and management leading to precision prevention and targeted interventions...
September 2018: Epidemiologia e Prevenzione
D Thomas, F Paillard, J M Lecerf, F Carré
The behavioral goals of the coronary patient require active management by the cardiologist. Every smoker must be clearly informed about the cardiovascular consequences of smoking and the major benefits of smoking cessation. The only advice to "quit smoking" is not enough. Validated "treatments" (cognitive-behavioral therapy, nicotine replacement therapy, varenicline, bupropion) must be used, with a precise strategy and prolonged follow-up. All drugs assistance can be prescribed in coronary patients and nicotine replacement therapy can even be used just after a myocardial infarction...
October 9, 2018: Annales de Cardiologie et D'angéiologie
Elena Aguilar-Aguilar, Helena Marcos-Pasero, Rocío de la Iglesia, Isabel Espinosa-Salinas, Ana Ramírez de Molina, Guillermo Reglero, Viviana Loria-Kohen
BACKGROUND AND OBJECTIVE: Multiple chemical sensitivity (MCS) is a complex, acquired, chronic syndrome of multifactorial etiology with multiple symptoms. The aim of the study was to assess the nutritional habits, dietary characteristics and physical activity, as well as their determinants, of a population diagnosed with MCS, which may allow for a more precise approach to nutritional improvement. PATIENTS AND METHOD: A descriptive, cross-sectional study in patients diagnosed with MCS...
October 8, 2018: Endocrinología, Diabetes y Nutrición
Shogo Sato, Evelyn B Parr, Brooke L Devlin, John A Hawley, Paolo Sassone-Corsi
OBJECTIVE: Advances in the field of metabolomics and the concomitant development of bioinformatics tools constitute a promising avenue towards the development of precision medicine and personalized profiling for numerous disease states. Studies in animal models have strengthened this concept, but the application in human subjects is scarce. METHODS: Utilizing high-throughput metabolomics, we have analyzed the metabolome levels of human serum and skeletal muscle in the morning and evening in response to divergent nutritional challenges in order to identify unique signatures present in serum and muscle...
October 2018: Molecular Metabolism
Victor L Fulgoni, Sanjiv Agarwal, Mark D Kellogg, Harris R Lieberman
Objectives: To develop age- and sex-specific RBC reference intervals using the National Health and Nutrition Examination Survey (NHANES) 1999 to 2012, a large nationally representative, population-based, cross-sectional database (n = 44,328). Methods: Comprehensive medical data were used to define a "healthy" population. Reference intervals for RBC count, hemoglobin, hematocrit, mean cell hemoglobin, mean cell hemoglobin concentration, mean cell volume, and red cell distribution width were computed using piecewise regression, an evidence-based statistical procedure that identifies breakpoints...
October 4, 2018: American Journal of Clinical Pathology
L A González, I Kyriazakis, L O Tedeschi
A plethora of sensors and information technologies with applications to the precision nutrition of herbivores have been developed and continue to be developed. The nutritional processes start outside of the animal body with the available feed (quantity and quality) and continue inside it once the feed is consumed, degraded in the gastrointestinal tract and metabolised by organs and tissues. Finally, some nutrients are wasted via urination, defecation and gaseous emissions through breathing and belching whereas remaining nutrients ensure maintenance and production...
October 2, 2018: Animal: An International Journal of Animal Bioscience
Tianxiao Yu, Yanjie Han, Xiaoyu Pu, Hujun Duan, Licai Zhi, Yao Zhang, Lingmei Lei, Yan Zhao, Qinying Cao, Hong Xu
BACKGROUND: Amino acid (AA) and acylcarnitine (AC) are important biomarkers of protein and fatty acid metabolism. Examining their levels in newborns may reveal multiple inherited metabolic diseases. However, they have rarely been assessed in very low birth weight (VLBW) neonates, low birth weight (LBW) neonates and rarely been compared with normal weight (NW) neonates. The aim of the study was to identify the AA and AC profiles in dried blood spot (DBS) specimens of LBW and VLBW neonates, then compare with NW neonates, and make a contribution to the determination of cutoff values of VLBW and LBW neonates...
September 1, 2018: Clinical Laboratory
Young Shin Hong, Ji Yeon Choi, Eun Yeong Nho, In Min Hwang, Naeem Khan, Nargis Jamila, Kyong Su Kim
BACKGROUND: Citrus fruits are widely consumed around the world. Several elements are known for important physiological functions in living things while some are reported to have toxic effects. This study was aimed to analyze the concentration of macro, micro and trace elements in citrus fruit varieties. The samples were acid digested using microwave system and analyzed for macro elements by inductively coupled plasma-optical emission spectrometry (ICP-OES) and micro and trace elements by inductively coupled plasma-mass spectrometry (ICP-MS)...
September 27, 2018: Journal of the Science of Food and Agriculture
Bianca Del-Ponte, Luciana Anselmi, Maria Cecília F Assunção, Luciana Tovo-Rodrigues, Tiago N Munhoz, Alicia Matijasevich, Luis Augusto Rohde, Iná S Santos
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is characterized by persistent symptoms of lack of attention, impulsivity and hyperactivity. The association between nutritional exposures and ADHD has been investigated and some studies have identified adverse effects from higher intake of sugar. The objective of the present study was to evaluate the association between change in sugar consumption between 6 and 11 years of age and incidence of attention-deficit/hyperactivity disorder (ADHD)...
January 15, 2019: Journal of Affective Disorders
Nikos V Margaritelis, Vassilis Paschalis, Anastasios A Theodorou, Antonios Kyparos, Michalis G Nikolaidis
The present review highlights the idea that antioxidant supplementation can be optimized when tailored to the precise antioxidant status of each individual. A novel methodologic approach involving personalized nutrition, the mechanisms by which antioxidant status regulates human metabolism and performance, and similarities between antioxidants and other nutritional supplements are described. The usefulness of higher-level phenotypes for data-driven personalized treatments is also explained. We conclude that personally tailored antioxidant interventions based on specific antioxidant inadequacies or deficiencies could result in improved exercise performance accompanied by consistent alterations in redox profile...
September 25, 2018: Advances in Nutrition
M Meddeb, H Oueslati, S Ksontini, S Omar, S Bahri
OBJECTIVES: Control of electrolyte concentration in mixtures for parenteral nutrition (MPN) for newborns is crucial before the release of the final product. We aimed to assess the validation of the electrolytes assay in MPN. METHODS: Electrolytes assay was performed with Ilyte Analyzer® . Validation of method was realized in accordance with ICH (International Conference on Harmonization) guideline Q2(R1) and the commission report of the French society of pharmaceutical science and technology...
September 20, 2018: Annales Pharmaceutiques Françaises
Adam D Kennedy, Bryan M Wittmann, Anne M Evans, Luke A D Miller, Douglas R Toal, Shaun Lonergan, Sarah H Elsea, Kirk L Pappan
Metabolomics is the untargeted measurement of the metabolome, which is comprised of the complement of small molecules detected in a biological sample. As such, metabolomic analysis produces a global biochemical phenotype. It is a technology that has been utilized in the research setting for over a decade. The metabolome is directly linked to and is influenced by genetics, epigenetics, environmental factors and the microbiome - all of which affect health. Metabolomics can be applied to human clinical diagnostics and to other fields such as veterinary medicine, nutrition, exercise, physiology, agriculture/plant biochemistry, and toxicology...
September 22, 2018: Journal of Mass Spectrometry: JMS
V Di Nardo, T Lotti
Many skin disorders have been associated with nutritional deficiencies, as well as many skin disorders, have been associated to diet-related immune mechanisms. The food can be a source of beneficial substances for healt, that act in very precise ways on the body and the functioning of each individual cells, tissues and organs. This article is protected by copyright. All rights reserved.
September 20, 2018: Dermatologic Therapy
Manuela De Gregori, Inna Belfer, Roberto De Giorgio, Maurizio Marchesini, Carolina Muscoli, Mariangela Rondanelli, Daniela Martini, Pedro Mena, Laura Isabel Arranz, Silvia Lorente-Cebrián, Simone Perna, Anna Villarini, Maurizio Salamone, Massimo Allegri, Michael E Schatman
This review is aimed to summarize the latest data regarding pain and nutrition, which have emerged during the second edition of Feed Your Destiny (FYD). Theme presentations and interactive discussions were held at a workshop on March 30, 2017, in Florence, Italy, during the 9th Annual Meeting of Study in Multidisciplinary Pain Research, where an international faculty, including recognized experts in nutrition and pain, reported the scientific evidence on this topic from various perspectives. Presentations were divided into two sections...
2018: Journal of Pain Research
Claudia Strafella, Valerio Caputo, Maria R Galota, Stefania Zampatti, Gianluca Marella, Silvestro Mauriello, Raffaella Cascella, Emiliano Giardina
One of the main challenges for healthcare systems is the increasing prevalence of neurodegenerative pathologies together with the rapidly aging populations. The enormous progresses made in the field of biomedical research and informatics have been crucial for improving the knowledge of how genes, epigenetic modifications, aging, nutrition, drugs and microbiome impact health and disease. In fact, the availability of high technology and computational facilities for large-scale analysis enabled a deeper investigation of neurodegenerative disorders, providing a more comprehensive overview of disease and encouraging the development of a precision medicine approach for these pathologies...
2018: Frontiers in Neurology
Youssef Rouphael, Marios C Kyriacou
Closed soilless cultivation systems (SCS) support high productivity and optimized year-round production of standardized quality. Efficiency and precision in modulating nutrient solution composition, in addition to controlling temperature, light, and atmospheric composition, renders protected SCS instrumental for augmenting organoleptic and bioactive components of quality. Effective application of eustress (positive stress), such as moderate salinity or nutritional stress, can elicit tailored plant responses involving the activation of physiological and molecular mechanisms and the strategic accumulation of bioactive compounds necessary for adaptation to suboptimal environments...
2018: Frontiers in Plant Science
Christian Ritz, Birgitte Rønn
For randomized controlled trials, the impact of the amount and handling of missing data on the interpretation of the treatment effect has been unclear. The current use of intention to treat, per protocol, and complete-case analysis has shortcomings. The use of estimands may lead to improved estimation of treatment effects through more precise characterizations of the fate of treatments after dropout or other post-randomization events. A perspective on current and future developments with a view toward clinical nutrition is provided...
September 2018: European Journal of Clinical Nutrition
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