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Intravoxel incoherent motion

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https://www.readbyqxmd.com/read/30328247/intravoxel-incoherent-motion-and-arterial-spin-labeling-mri-analysis-of-reversible-unilateral-ureteral-obstruction-in-rats
#1
Genwen Hu, Zhong Yang, Wen Liang, Caiyong Lai, Yingjie Mei, Yufa Li, Jianmin Xu, Liangping Luo, Xianyue Quan
BACKGROUND: Renal fibrosis is a common consequence of chronic kidney disease (CKD) and is the mechanism by which various forms of CKD progress to endstage renal failure. Accurate assessment of renal fibrosis is important for treatment. PURPOSE: To measure longitudinal changes of intravoxel incoherent motion (IVIM) and arterial spin labeling (ASL) before and after reversible unilateral ureteral obstruction in an animal model. STUDY TYPE: Self-controlled animal study...
October 16, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30306712/predicting-post-operative-pancreatic-fistulae-using-preoperative-pancreatic-imaging-a-systematic-review
#2
REVIEW
Savio G Barreto, Ilse Dirkzwager, John A Windsor, Sanjay Pandanaboyana
BACKGROUND: Post-operative pancreatic fistulae (POPF) remain a major contributor to morbidity and mortality following pancreatic resection. Evidence for preoperative prediction of POPF based on cross-sectional imaging has not been systemically reviewed. This review aimed to determine whether preoperative imaging modalities can accurately predict the development of POPF. METHODS: A systematic review of major reference databases was undertaken, according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, up to May 2018...
October 10, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/30292252/preoperative-evaluation-of-pelvine-lymph-node-metastasis-in-high-risk-prostate-cancer-with-intravoxel-incoherent-motion-ivim-mri
#3
Markus Sauer, Christiane Klene, Michael Kaul, Azien Quitzke, Maxim Avanesov, Cyrus Behzadi, Lars Budäus, Dirk Beyersdorff, Gerhard Adam, Marc Regier
OBJECTIVES: To evaluate benign and malignant pelvine lymph nodes in prostate cancer patients with biexponential intravoxel incoherent motion (IVIM) MRI of the prostate prior to radical prostatectomy. METHODS: The ethics committee approved this retrospective study with waiver of informed consent. From February 2012 to November 2013 43 patients with histopathologically proven prostatic cancer were included. All patients were examined applying a standardized MRI protocol including IVIM diffusion weighted imaging with multiple b-values ranging from 0 to 950 s/mm²...
October 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/30285893/radiation-induced-parotid-changes-in-oropharyngeal-cancer-patients-the-role-of-early-functional-imaging-and-patient-treatment-related-factors
#4
Simona Marzi, Alessia Farneti, Antonello Vidiri, Francesca Di Giuliano, Laura Marucci, Filomena Spasiano, Irene Terrenato, Giuseppe Sanguineti
BACKGROUND: Functional magnetic resonance imaging may provide several quantitative indices strictly related to distinctive tissue signatures with radiobiological relevance, such as tissue cellular density and vascular perfusion. The role of Intravoxel Incoherent Motion Diffusion Weighted Imaging (IVIM-DWI) and Dynamic Contrast-Enhanced (DCE) MRI in detecting/predicting radiation-induced volumetric changes of parotids both during and shortly after (chemo)radiotherapy of oropharyngeal squamous cell carcinoma (SCC) was explored...
October 1, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/30276853/effect-of-flow-encoding-strength-on-intravoxel-incoherent-motion-in-the-liver
#5
Kévin Moulin, Eric Aliotta, Daniel B Ennis
PURPOSE: To study the impact of variable flow-encoding strength on intravoxel incoherent motion (IVIM) liver imaging of diffusion and perfusion. THEORY: Signal attenuation in DWI arises from (1) intravoxel microvascular blood flow, which depends on the flow-encoding strength α (first gradient moment) of the diffusion-encoding waveform, and (2) intravoxel spin diffusion, which depends on the b-value of the diffusion-encoding gradient waveforms α and b-value. Both are linked to the diffusion-encoding gradient waveform and conventionally are not independently controlled...
September 12, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/30268719/correlation-between-intravoxel-incoherent-motion-and-dynamic-contrast-enhanced-magnetic-resonance-imaging-parameters-in-rectal-cancer
#6
Hongliang Sun, Yanyan Xu, Qiaoyu Xu, Jianghui Duan, Haibo Zhang, Tongxi Liu, Lu Li, Queenie Chan, Sheng Xie, Wu Wang
RATIONALE AND OBJECTIVES: This study aimed to determine the correlation between intravoxel incoherent motion (IVIM) and multiphase dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) quantitative parameters in patients with rectal cancer. MATERIALS AND METHODS: Ninety-seven patients with rectal cancer were included in this study. All pelvic MRI examinations were performed in a 3.0 T MR unit, including diffusion-weighted imaging with 16 b values, DCE-MRI with two different flip angles (5° and 10°, respectively), and T1-fast field echo sequences as the reference...
September 26, 2018: Academic Radiology
https://www.readbyqxmd.com/read/30264445/enhancing-intravoxel-incoherent-motion-parameter-mapping-in-the-brain-using-k-b-pca
#7
Georg R Spinner, Johannes F M Schmidt, Constantin von Deuster, Christian Federau, Christian T Stoeck, Sebastian Kozerke
Intravoxel incoherent motion (IVIM) imaging of diffusion and perfusion parameters in the brain using parallel imaging suffers from local noise amplification. To address the issue, signal correlations in space and along the diffusion encoding dimension are exploited jointly using a constrained image reconstruction approach. IVIM imaging was performed on a clinical 3 T MR system with diffusion weighting along six gradient directions and 16 b-values encoded per direction across a range of 0-900 s/mm2 . Data were collected in 11 subjects, retrospectively undersampled in k-space with net factors ranging from 2 to 6 and reconstructed using CG-SENSE and the proposed k-b PCA approach...
September 28, 2018: NMR in Biomedicine
https://www.readbyqxmd.com/read/30255258/differentiating-between-malignant-and-benign-solid-solitary-pulmonary-lesions-are-intravoxel-incoherent-motion-and-diffusion-kurtosis-imaging-superior-to-conventional-diffusion-weighted-imaging
#8
Qi Wan, Ying-Shi Deng, Qiang Lei, Ying-Ying Bao, Yu-Ze Wang, Jia-Xuan Zhou, Qiao Zou, Xin-Chun Li
OBJECTIVE: To quantitatively compare the diagnostic values of various diffusion parameters obtained from mono- and biexponential diffusion-weighted imaging (DWI) models and diffusion kurtosis imaging (DKI) in differentiating between benign and malignant solitary pulmonary lesions (SPLs). METHODS: Multiple b-value DWIs and DKIs were performed in 89 patients with SPL by using a 3-T magnetic resonance (MR) imaging unit. The apparent diffusion coefficient (ADC) of various b-value sets, true diffusivity (D), pseudo-diffusion coefficient (D*), perfusion fraction (f), apparent diffusional kurtosis (Kapp ), and kurtosis-corrected diffusion coefficient (Dapp ) were calculated and compared between the malignant and benign groups using a Mann-Whitney U test...
September 25, 2018: European Radiology
https://www.readbyqxmd.com/read/30250578/intravoxel-incoherent-motion-magnetic-resonance-imaging-for-breast-cancer-a-comparison-with-benign-lesions-and-evaluation-of-heterogeneity-in-different-tumor-regions-with-prognostic-factors-and-molecular-classification
#9
Ming Zhao, Kuang Fu, Lei Zhang, Wenhui Guo, Qiong Wu, Xue Bai, Ziyao Li, Qiang Guo, Jiawei Tian
The objective of the present study was to compare the differentiation between breast cancer and benign breast lesions and study regional distribution characteristics in various subtypes of breast cancer using intravoxel incoherent motion (IVIM) parameters. This retrospective study involved 119 patients with breast cancer and 22 patients with benign breast lesions, who underwent 3.0T breast magnetic resonance imaging examinations. The apparent diffusion coefficient (ADC) and IVIM parameters (slow ADC, fast ADC and fraction of fast ADC) were obtained from patients with breast cancer and benign lesions using diffusion-weighted imaging (DWI) with b-values of 0, 50, 100, 150, 200, 400, 500, 1,000 and 1,500 sec/mm2 ...
October 2018: Oncology Letters
https://www.readbyqxmd.com/read/30244589/intravoxel-incoherent-motion-imaging-in-monitoring-the-function-of-kidney-allograft
#10
Katarzyna Sulkowska, Piotr Palczewski, Damian Wojcik, Michal Ciszek, Joanna Sanko-Resmer, Joanna Wojtowicz, Marek Leszkiewicz, Marek Golebiowski
Background Non-invasive alternatives to percutaneous renal biopsy are sought for follow-up of renal allografts. Purpose To evaluate the feasibility of intravoxel incoherent motion (IVIM) imaging in monitoring and predicting the function of renal allografts. Material and Methods Thirty-five kidney recipients were examined on a 1.5-T MR unit approximately three and 18 months after transplantation. Based on estimated glomerular filtration rate (eGFR), patients were divided into three groups: improved; declined; and stable graft function...
September 23, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/30238533/intravoxel-incoherent-motion-diffusion-weighted-mri-of-invasive-breast-cancer-correlation-with-prognostic-factors-and-kinetic-features-acquired-with-computer-aided-diagnosis
#11
Sung Eun Song, Kyu Ran Cho, Bo Kyoung Seo, Ok Hee Woo, Kyong Hwa Park, Yo Han Son, Robert Grimm
BACKGROUND: As both intravoxel incoherent motion (IVIM) modeling and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) provide perfusion parameters, IVIM-derived perfusion parameters might be expected to correlate with the kinetic features from DCE-MRI. PURPOSE: To investigate the association between IVIM parameters and prognostic factors and to evaluate the correlation between IVIM parameters and kinetic features in invasive breast cancer patients using computer-aided diagnosis (CAD)...
September 20, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30232311/-capillary-blood-flow-of-muscle-before-and-after-the-exercise-used-by-intravoxel-incoherent-motion
#12
Hana Sotome, Akio Ogura, Ayumi Asai, Atsuya Fuju
Capillaries are the most basic and important blood vessel of the circulatory systems. The evaluation of the blood flow may contribute to many studies in future. We evaluated the capillary blood flow change of lower limb muscle over time before and after the exercise used by magnetic resonance imaging-intravoxel incoherent motion (MRI-IVIM) obtained perfusion information. Furthermore, we examined an association between the muscle pain after the exercise and the diffusion weighted image (DWI) indexes. DWI was imaged using multi-b values for a thigh and calf muscles...
2018: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/30221622/intravoxel-incoherent-motion-mri-in-neurological-and-cerebrovascular-diseases
#13
REVIEW
André M Paschoal, Renata F Leoni, Antonio C Dos Santos, Fernando F Paiva
Intravoxel Incoherent Motion (IVIM) is a recently rediscovered noninvasive magnetic resonance imaging (MRI) method based on diffusion-weighted imaging. It enables the separation of the intravoxel signal into diffusion due to Brownian motion and perfusion-related contributions and provides important information on microperfusion in the tissue and therefore it is a promising tool for applications in neurological and neurovascular diseases. This review focuses on the basic principles and outputs of IVIM and details it major applications in the brain, such as stroke, tumor, and cerebral small vessel disease...
August 31, 2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/30216762/determination-of-hepatocellular-carcinoma-and-characterization-of-hepatic-focal-lesions-with-adaptive-multi-exponential-intravoxel-incoherent-motion-model
#14
Hong-Xia Zhang, Xiu-Shi Zhang, Zi-Xiang Kuai, Yang Zhou, Yun-Feng Sun, Zhi-Chang Ba, Kuang-Bang He, Xi-Qiao Sang, Yuan-Fei Yao, Chun-Yu Chu, Yue-Min Zhu
PURPOSE: To distinguish hepatocellular carcinoma (HCC) from other types of hepatic lesions with the adaptive multi-exponential IVIM model. METHODS: 94 hepatic focal lesions, including 38 HCC, 16 metastasis, 12 focal nodular hyperplasia, 13 cholangiocarcinoma, and 15 hemangioma, were examined in this study. Diffusion-weighted images were acquired with 13 b values (b = 0, 3, …, 500 s/mm2 ) to measure the adaptive multi-exponential IVIM parameters, namely, pure diffusion coefficient (D), diffusion fraction (fd ), pseudo-diffusion coefficient (Di *) and perfusion-related diffusion fraction (fi ) of the ith perfusion component...
September 11, 2018: Translational Oncology
https://www.readbyqxmd.com/read/30194746/measurements-of-diffusion-and-perfusion-in-vertebral-bone-marrow-using-intravoxel-incoherent-motion-ivim-with-multishot-readout-segmented-resolve-echo-planar-imaging
#15
Jérémy Lasbleiz, Caroline Le Ster, Raphaël Guillin, Hervé Saint-Jalmes, Giulio Gambarota
BACKGROUND: A limited number of studies have used the intravoxel incoherent motion (IVIM) approach on bone marrow. In none of the previous studies were the effects of fat suppression on the IVIM parameters investigated. PURPOSE: To measure the water diffusion coefficient and the perfusion fraction in vertebral bone marrow using IVIM with multishot, readout-segmented (RESOLVE) echo-planar imaging and to assess the effects of different fat suppression techniques on the measurement of the IVIM parameters...
September 8, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/30146728/image-acquisition-for-intravoxel-incoherent-motion-imaging-of-kidneys-should-be-triggered-at-the-instant-of-maximum-blood-velocity-evidence-obtained-with-simulations-and-in-vivo-experiments
#16
Bastien Milani, Jean-Baptiste Ledoux, David C Rotzinger, Michiko Kanemitsu, Jean-Paul Vallée, Michel Burnier, Menno Pruijm
PURPOSE: To demonstrate that diffusion-weighted images should be acquired at the instant of maximum blood velocity in kidneys to extract the perfusion fraction (PF) by the bi-exponential intravoxel incoherent motion model. METHODS: The PF values were measured in Monte-Carlo simulations corresponding to different blood velocities with a constant known PF. The distribution of the measured PF values (PF-distribution) was characterized quantitatively by 3 markers highlighting the deviation of the measurement from the true PF...
August 26, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/30142864/meta-analysis-of-intravoxel-incoherent-motion-magnetic-resonance-imaging-in-differentiating-focal-lesions-of-the-liver
#17
REVIEW
Hongzhen Wu, Yingying Liang, Xinqing Jiang, Xinhua Wei, Yu Liu, Weifeng Liu, Yuan Guo, Wenjie Tang
INTRODUCTION: Accurate detection and characterization of focal liver lesions, including differentiation between malignant and benign lesions, are particularly important. The objective of this meta-analysis was to evaluate the parameters of intravoxel incoherent motion (IVIM), including apparent diffusion coefficient (ADC), pure molecular diffusion coefficient (D), perfusion-related diffusion coefficient (D*), and perfusion fraction (f) in differentiating focal liver lesions. METHODS: IVIM method employed for focal liver lesion and the quality assessment of diagnostic studies were evaluated...
August 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30138995/-preliminary-study-of-whole-tumor-volume-analysis-of-mono-exponential-and-intravoxel-incoherent-motion-models-in-the-preoperative-histologic-grading-of-hepatocellular-carcinoma
#18
Y Wei, F F Gao, Z X Huang, H H Tang, M Wang, Y Wang, T Zhang, B Song
Objective: To investigate the diagnostic performance of whole-tumor volume analysis of mono-exponential and intravoxel incoherent motion (IVIM)parameters in the preoperative grading of hepatocellular carcinoma (HCC). Methods: A total of 106 patients who undewent parital hepatectomy were prospectively enrolled and underwent with routine MR and IVIM examination.112 HCCs were confirmed by the surgical pathology.The original images of IVIM were imported into the GE AW 4.6 workstation.Two independent radiologist who were blinded to the histopathological results analyzed the data...
August 21, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30116979/comparison-of-methods-for-estimation-of-the-intravoxel-incoherent-motion-ivim-diffusion-coefficient-d-and-perfusion-fraction-f
#19
Oscar Jalnefjord, Mats Andersson, Mikael Montelius, Göran Starck, Anna-Karin Elf, Viktor Johanson, Johanna Svensson, Maria Ljungberg
OBJECTIVE: Intravoxel incoherent motion (IVIM) shows great potential in many applications, e.g., tumor tissue characterization. To reduce image-quality demands, various IVIM analysis approaches restricted to the diffusion coefficient (D) and the perfusion fraction (f) are increasingly being employed. In this work, the impact of estimation approach for D and f is studied. MATERIALS AND METHODS: Four approaches for estimating D and f were studied: segmented IVIM fitting, least-squares fitting of a simplified IVIM model (sIVIM), and Bayesian fitting of the sIVIM model using marginal posterior modes or posterior means...
August 16, 2018: Magma
https://www.readbyqxmd.com/read/30114928/perfusion-sensitive-parameters-of-intravoxel-incoherent-motion-mri-in-rectal-cancer-evaluation-of-reproducibility-and-correlation-with-dynamic-contrast-enhanced-mri
#20
Xinyue Yang, Xiaojuan Xiao, Baolan Lu, Yan Chen, Ziqiang Wen, Shenping Yu
Background Intravoxel incoherent motion magnetic resonance imaging (IVIM-MRI) acquires tumor perfusion information without injection of contrast medium, which is promising in tumor assessment. However, its consistency with dynamic contrast-enhanced MRI (DCE-MRI), a more widely used method for tumor perfusion evaluation, is not revealed in rectal cancer. Purpose In this study, we aimed to investigate the correlation of perfusion-sensitive parameters derived from IVIM-MRI with DCE-MRI and measurement reproducibility of IVIM-MRI parameters in rectal cancer...
August 16, 2018: Acta Radiologica
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