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antihypertensive therapy

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https://www.readbyqxmd.com/read/30540406/poor-oral-health-and-blood-pressure-control-among-us-hypertensive-adults-results-from-the-national-health-and-nutrition-examination-survey-2009-to-2014
#1
Davide Pietropaoli, Rita Del Pinto, Claudio Ferri, Jackson T. Wright, Mario Giannoni, Eleonora Ortu, Annalisa Monaco
Periodontal disease is a chronic inflammatory disorder of the tissues surrounding the teeth, with evidence of systemic effects. Some studies showed the benefit of periodontal therapy on blood pressure (BP), but the impact of periodontitis on BP control is unknown. We retrospectively analyzed cross-sectional, nationally representative data from treated hypertensive adults aged ≥30 years with and without periodontitis. BP was examined as both continuous (mm Hg) and categorical (treatment goal achievement status according to guidelines: at goal and above goal) variable according to the presence or absence of periodontitis and its clinical parameters (probing depth, clinical attachment loss, and disease severity [mild, moderate, and severe])...
October 22, 2018: Hypertension
https://www.readbyqxmd.com/read/30538790/in-glaucoma-patients-low-blood-pressure-is-accompanied-by-vascular-dysregulation
#2
Tatjana Binggeli, Andreas Schoetzau, Katarzyna Konieczka
Background: There are many risk factors contributing to glaucomatous optic neuropathy. Beside increased intraocular pressure, vascular factors play a prominent role, particularly low blood pressure (BP), and vascular dysregulation. Both of them are essential components of the Flammer syndrome. The aim of this retrospective study was to evaluate whether in glaucoma patients there is a relationship between vascular dysregulation and the BP. Methods: Medical records of 57 unselected glaucoma patients were retrospectively studied...
December 2018: EPMA Journal
https://www.readbyqxmd.com/read/30537701/in-vivo-assessment-of-combined-effects-of-glibenclamide-and-losartan-in-diabetic-rats
#3
Moureq R Alotaibi, Amal J Fatani, Ahmed T Almnaizel, Mohammed M Ahmed, Hatem M Abuohashish, Salim S Al-Rejaie
OBJECTIVE: Diabetic complications involve multiple pathological pathways, including hyperglycemia-induced oxidative stress and inflammation. Combination therapy is usually employed to improve treatment outcomes and to lower potential adverse effects. In this study, we evaluated the effects of antidiabetic and antihypertensive agents, glibenclamide (GLI) and losartan (LT), on diabetes-associated metabolic changes in rats. MATERIALS AND METHODS: Streptozotocin (STZ)-induced diabetic animals were orally treated with GLI and/or LT 5 and 25 mg/kg respectively for 4 weeks...
December 10, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/30530462/a-novel-just-in-time-contextual-mobile-app-intervention-to-reduce-sodium-intake-in-hypertension-protocol-and-rationale-for-a-randomized-controlled-trial-lowsalt4life-trial
#4
Michael P Dorsch, Lawrence C An, Scott L Hummel
BACKGROUND: High sodium intake is a significant public health problem in the United States. Interventions that lower sodium intake can decrease blood pressure and improve cardiovascular outcomes. Restaurants and grocery stores are prime targets for intervention with about 77% of all sodium intake in the average US diet coming from processed and restaurant foods. OBJECTIVE: This study proposes that a mobile app intervention that promotes low-sodium alternatives at grocery stores and restaurants will reduce dietary intake of sodium and improve confidence following a low-sodium diet in hypertension...
December 7, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/30527153/hypotensive-effect-of-heated-water-based-exercise-persists-after-12-week-cessation-of-training-in-patients-with-resistant-hypertension
#5
Guilherme Veiga Guimãraes, Miguel Morita Fernandes-Silva, Luciano Ferreira Drager, Lais Galvani de Barros Cruz, Rafael Ertner Castro, Emmanuel Gomes Ciolac, Edimar Alcides Bocchi
BACKGROUND: Heated water-based exercise (HEx) promotes a marked reduction of blood pressure (BP), but it is not entirely clear whether its effects on BP persist after cessation of HEx. METHODS: We analyzed the effects of cessation of HEx on 24-hour ambulatory BP monitoring (ABPM) in patients with resistant hypertension (RH). Thirty-two patients (aged 53 ± 6 years) with RH (4 to 6 antihypertensive drugs) were randomly assigned to HEx (n = 16) or control (n = 16) groups...
December 2018: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/30525343/poor-oral-health-and-blood-pressure-control-among-us-hypertensive-adults-results-from-the-national-health-and-nutrition-examination-survey-2009-to-2014
#6
Davide Pietropaoli, Rita Del Pinto, Claudio Ferri, Jackson T. Wright, Mario Giannoni, Eleonora Ortu, Annalisa Monaco
Periodontal disease is a chronic inflammatory disorder of the tissues surrounding the teeth, with evidence of systemic effects. Some studies showed the benefit of periodontal therapy on blood pressure (BP), but the impact of periodontitis on BP control is unknown. We retrospectively analyzed cross-sectional, nationally representative data from treated hypertensive adults aged ≥30 years with and without periodontitis. BP was examined as both continuous (mm Hg) and categorical (treatment goal achievement status according to guidelines: at goal and above goal) variable according to the presence or absence of periodontitis and its clinical parameters (probing depth, clinical attachment loss, and disease severity [mild, moderate, and severe])...
October 22, 2018: Hypertension
https://www.readbyqxmd.com/read/30525273/the-impact-of-apelin-and-relaxin-plasma-levels-in-masked-hypertension-and-white-coat-hypertension
#7
Elias Sanidas, Kostas Tsakalis, Dimitrios P Papadopoulos, Kanella Zerva, Maria Velliou, Despoina Perrea, Marina Mantzourani, Dimitrios Iliopoulos, John Barbetseas
Masked hypertension (HTN) and white coat hypertension represent two reverse forms of clinical HTN with questionable prognostic significance. Recent evidence supports that low apelin and relaxin plasma levels contribute to vascular damage accelerating atherogenesis and predisposing to HTN and cardiovascular (CV) events. The aim of this study was to compare apelin and relaxin plasma levels between patients with masked hypertension (MH) and those with white coat HTN (WCH). Overall, 130 patients not receiving antihypertensive therapy were studied...
December 7, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/30525180/resistant-and-refractory-hypertension-two-sides-of-the-same-disease
#8
Elizabeth Silaid Muxfeldt, Bernardo Chedier, Cibele Isaac Saad Rodrigues
Refractory hypertension (RfH) is an extreme phenotype of resistant hypertension (RH), being considered an uncontrolled blood pressure besides the use of 5 or more antihypertensive medications, including a long-acting thiazide diuretic and a mineralocorticoid antagonist. RH is common, with 10-20% of the general hypertensives, and its associated with renin angiotensin aldosterone system hyperactivity and excess fluid retention. RfH comprises 5-8% of the RH and seems to be influenced by increased sympathetic activity...
December 6, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/30521476/beneficial-effects-of-combined-therapy-with-lacidipine-and-candesartan-in-obese-hypertensive-patients
#9
Tatiana Ashcheulova, Nina Gerasimchuk, Olga Kovalyova, Oleksii Honchar
INTRODUCTION: Obesity is becoming one of the leading risk factors of coronary heart disease, hypertension, cerebrovascular disease. Despite the presence of a large number of antihypertensive agents and scientific substantiation of antihypertensive treatment principles it would be wrong to assume that the problem is completely solved. Development of endothelial dysfunction is one of the key pathogenic mechanisms in hypertension. This process is proven to have contributed by immune inflammation activation which is mediated by pro-inflammatory cytokines and oxidative stress...
December 1, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/30517405/association-between-follow-up-in-health-services-and-antihypertensive-medication-adherence
#10
Nila Larisse Silva de Albuquerque, Andressa Suelly Saturnino de Oliveira, Jacqueline Mota da Silva, Thelma Leite de Araújo
OBJECTIVE: To analyze the association between the characteristics of follow-up in health services and adherence to antihypertensive medication in patients with cardiovascular disease. METHOD: Analytical study carried out with 270 patients suffering from hypertension and hospitalized due to cardiovascular complications. Data collection occurred between November 2015 and April 2016, involving sociodemographic variables, presence of self-reported diabetes, accessibility and use of health services, blood pressure levels and medication adherence (analyzed through the Morisky-Green Test)...
November 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/30503066/adherence-to-treatment-of-hypertension-hypercholesterolaemia-and-diabetes-in-an-elderly-population-of-a-spanish-cohort
#11
Aida Moreno Juste, Antonio Gimeno Miguel, Beatriz Poblador Plou, Francisca González Rubio, María Mercedes Aza Pascual-Salcedo, Enrica Menditto, Alexandra Prados Torres
BACKGROUND AND OBJECTIVE: Sub-optimal adherence to treatment in the general population has been highlighted in several studies, especially in the elderly and/or chronic patients. This study aims to describe the adherence to treatment of diabetes mellitus, dyslipidaemia and hypertension, and to identify the factors that influence adherence. MATERIAL AND METHOD: Retrospective, cross-sectional observational study on 16,208 patients aged ≥65 years from the EpiChron Cohort who initiated monotherapy treatment of an antidiabetic, a lipid-lowering or an antihypertensive medication in 2010...
November 29, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/30500867/how-to-improve-patients-adherence-to-antihypertensive-therapy-a-simple-solution-for-a-big-trouble
#12
Giuliano Tocci, Vivianne Presta, Massimo Volpe
No abstract text is available yet for this article.
November 30, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/30499540/-molecular-mechanisms-of-neuroretinoprotection-in-primary-open-angle-glaucoma
#13
A F Gabdrakhmanova, L F Aznabaeva, G Sh Abizgil'dina, S A Kurbanov
PURPOSE: To evaluate the effectiveness of neuroprotective therapy in patients with primary open-angle glaucoma based on specific biochemical markers of neurotrophy and neurodegeneration. MATERIAL AND METHODS: In the course of the study, lacrimal fluid (LF) of 23 patients (46 eyes) with stage I-II primary open angle glaucoma (POAG) aged 66.3±10.8 was examined. The control group consisted of healthy individuals (12 control LF samples). Local antihypertensive therapy was complimented with 10 intramuscular injections of retinalamin (GEROPHARM LLC, St...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/30499507/-possible-applications-of-rac-hopantenic-acid-in-the-treatment-of-cognitive-anxiety-and-depressive-disorders-in-patients-with-essential-arterial-hypertension
#14
O D Ostroumova
Essential arterial hypertension (AH) is one of the main risk factors for the development of cognitive impairment and dementia. Cognitive decline is an early sign of brain damage as a target organ of hypertension, it occurs even in patients with uncomplicated hypertension with minimal duration of disease. Cognitive impairment progresses with increasing age and hypertension duration, as well as in non-controlled AH. In patients with hypertension, the prevalence of emotional disorders - anxiety and depression is also high...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/30499486/-the-application-of-bioresonance-therapy-for-the-correction-of-the-overtrained-athlete-syndrome
#15
V A Badtieva, V I Pavlov, M N Khokhlova, A V Pachina
BACKGROUND: Physical overload results in the development of pathological changes in the organs and systems and thereby causes their dysfunction. This leads to disadaptation, vegetative imbalance, and disturbances in the cardiovascular, nervous, endocrine and other systems. Taken together, these changes give rise to a syndrome of overtraining. In this context, the pathogenetically sound method of therapy appears to be the most suitable for the management of this condition based on the physiotherapeutic non-invasive interventions for the correction of physiological characteristics and the psycho-emotional status of the patients...
2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/30498887/atypical-mri-presentation-of-posterior-reversible-encephalopathy-syndrome-with-predominant-brainstem-involvement
#16
Benjamin Hebant, Evelyne Guegan-Massardier, Aude Triquenot-Bagan, Ozlem Ozkul-Wermester
We report here the case of a 80-year-old woman for the assessment of an acute confusional state since 2 days asssociated with diffuse and gradual headache. Brain MRI disclosed isolated hyperintense signal on fluid-attenuated inversion recovery sequence involving the medulla and the right inferior cerebellar peduncle with moderate swelling, consistent with vasogenic oedema, without abnormalities on diffusion-weighted imaging sequence. PRES diagnosis was suspected and antihypertensive therapy was introduced to achieve a blood pressure goal < 140/90 mmHg, allowing a quickly favourable clinical course...
November 29, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/30497161/ace-inhibitors-a-preventive-measure-for-bone-flap-resorption-after-autologous-cranioplasty
#17
(no author information available yet)
OBJECTIVEDecompressive craniectomy (DC) is an established treatment for refractory intracranial hypertension. It is usually followed by autologous cranioplasty (AC), the reinsertion of a patient's explanted bone flap. A frequent long-term complication of AC is bone flap resorption (BFR), which results in disfigurement as well as loss of the protective covering of the brain. This study investigates risk factors for BFR after AC, including medical conditions and antihypertensive drug therapies, with a focus on angiotensin-converting enzyme inhibitors (ACEIs), which have been associated with a beneficial effect on bone healing and bone preservation in orthopedic, osteoporosis, and endocrinology research...
November 1, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/30489456/analytical-validity-of-a-genotyping-assay-for-use-with-personalized-antihypertensive-and-chronic-kidney-disease-therapy
#18
Kimberly S Collins, Victoria M Pratt, Wesley M Stansberry, Elizabeth B Medeiros, Karthik Kannegolla, Marelize Swart, Todd C Skaar, Arlene B Chapman, Brian S Decker, Ranjani N Moorthi, Michael T Eadon
Hypertension and chronic kidney disease are inextricably linked. Hypertension is a well-recognized contributor to chronic kidney disease progression and, in turn, renal disease potentiates hypertension. A generalized approach to drug selection and dosage has not proven effective in managing these conditions, in part, because patients with heterogeneous kidney disease and hypertension etiologies are frequently grouped according to functional or severity classifications. Genetic testing may serve as an important tool in the armamentarium of clinicians who embrace precision medicine...
November 26, 2018: Pharmacogenetics and Genomics
https://www.readbyqxmd.com/read/30485471/discontinuation-and-nonadherence-to-medications-for-chronic-conditions-after-hematopoietic-cell-transplantation-a-six-year-propensity-score-matched-cohort-study
#19
Jifang Zhou, Jin Han, Edith A Nutescu, Pritesh R Patel, Karen Sweiss, Gregory S Calip
INTRODUCTION: Hematopoietic cell transplantation (HCT) is an established curative option for patients with hematological malignancies and other life-threatening conditions. Evidence on nonpersistence and nonadherence to oral medications for chronic conditions among patients following HCT is lacking. OBJECTIVES: This study aims to examine patterns of oral medication use for chronic conditions following HCT in the United States population. METHODS: Nonpersistence and nonadherence to oral medications for diabetes, hypertension, and dyslipidemia among HCT recipients were assessed in a cohort that included 1382 autologous and 650 allogeneic HCT recipients with hematological malignancies using the Truven Health MarketScan® Research Database between 2009 and 2014...
November 28, 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/30484292/the-phospholipid-fraction-obtained-from-egg-yolk-reduces-blood-pressure-increase-induced-by-acute-stress-in-spontaneously-hypertensive-rats
#20
Helena Martynowicz, Dorian Nowacki, Grzegorz Mazur, Tadeusz Trziszka, Andrzej Szuba
BACKGROUND: Despite continuous research, an improved understanding of the pathophysiology of hypertension and the development of new antihypertensive therapies, hypertension is still the most prevalent chronic cardiovascular disease (CVD) among adults in Western societies. Stress is a common factor related to cardiovascular morbidity. An increase in blood pressure is one of the most common reactions to stress. Chronic and acute stress have also been related to cardiovascular disorders...
November 28, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
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