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Xiaodong Yang, Cheng Zhan, Ming Li, Yiwei Huang, Mengnan Zhao, Xinyu Yang, Zongwu Lin, Yu Shi, Wei Jiang, Qun Wang
BACKGROUND: The optimal surgical approach for metachronous second primary lung cancer (MSPLC) has not been well established yet. In this study, survival outcome of lobectomy was compared with sublobectomy for MSPLC. METHODS: A retrospective study was conducted based on the Surveillance, Epidemiology, and End Results database. Propensity score matching was used to reduce the potential bias caused by the variance of the clinicopathologic features of the first and second lung cancer...
September 2018: Annals of Thoracic Surgery
Yiwei Huang, Xiaodong Yang, Tao Lu, Ming Li, Mengnan Zhao, Xingyu Yang, Ke Ma, Shuai Wang, Cheng Zhan, Yu Liu, Qun Wang
Previous studies have identified potential risk factors for pulmonary carcinoid tumors and evaluated the effect of various treatments; however, the results were not entirely consistent. We conducted a population-based study to further explore relevant prognostic issues. We extracted cases with pulmonary carcinoid tumors from the Surveillance Epidemiology and End Results database. Cox proportional hazard regression was utilized to identify potential significant risk factors, which helped establish a nomogram for predicting long-term survival...
June 2018: Cancer Medicine
Haikang Zeng, Yang Liu, Xiaojun Xia, Jin Li, Jianxing He
BACKGROUND: Currently, the prognosis of lobectomy and sub-lobectomy for the treatment of stage Ia small cell lung cancer (SCLC) is rarely reported. We retrospectively studied T1N0M0 (≤3 cm) SCLC patients aged ≥60 years, aiming to comparatively analyze the prognosis of lobectomy and sub-lobectomy in treating patients with Ia SCLC. METHODS: Patients with stage Ia SCLC diagnosed by pathologic between 1992 and 2010 were selected from the "Surveillance, Epidemiology and End Results database"(SEER)...
January 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Haiping Yang, Yaofeng Yun, Yu Mao
The present study investigated and analyzed the clinical impact of sublobectomy on pulmonary functions.Changes in pulmonary function before and after sublobectomy were compared to the changes after lobectomy.Changes in the pulmonary function before and after sublobectomy and lobectomy did not exhibit remarkable differences in long-term effects. Surgery-related indexes of the sublobectomy group were significantly lower than those of the lobectomy group (P < .05). The indexes of pulmonary function both before and after surgery in the sublobectomy group were not associated with a significant decrease in the quality of survival based on pulmonary function as the main index (P > ...
December 2017: Medicine (Baltimore)
Siyuan Dong, Lin Zhang
Lung cancer continues to be one of the leading causes of cancer-related mortality worldwide and its incidence is still increasing. With aging population and development in imaging technology, many more elderly with early-stage lung cancers are being diagnosed than in the past. Lobectomy and sub-lobar resection are two main surgical approach for the treatment for this kind of patients. This review aimed to compare these two methods for this hot issue.
October 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Jian Li, Yongsheng Zhao, Chuan Li, Longfei Zhu, Chengwu Liu, Lunxu Liu
OBJECTIVES: The 8th edition TNM lung cancer classification was enacted in January 2017. An important change is the old T2a was revised to new T2a and T2b. Whether a postoperative survival difference exists between the two stages is still undefined. The purpose of this study is to investigate the postoperative outcomes of small cell lung cancer (SCLC) patients and compare the survival difference between the two stages. METHODS: Data of patients with SCLC who underwent surgery between October 2005 and August 2013 at our institute were reviewed...
December 2017: International Journal of Surgery
Todd A Pezzi, Abdallah S R Mohamed, Clifton D Fuller, Pierre Blanchard, Christopher Pezzi, Boris Sepesi, Stephen M Hahn, Daniel R Gomez, Stephen G Chun
BACKGROUND: The 1998 post-operative radiotherapy meta-analysis for lung cancer showed a survival detriment associated with radiation for stage I-II resected non-small cell lung cancer (NSCLC), but has been criticized for including antiquated radiation techniques. We analyzed the National Cancer Database (NCDB) to determine the impact of radiation after margin-negative (R0) resection for stage I-II NSCLC on survival. METHODS: Adult patients from 2004 to 2014 were analyzed from the NCDB with respect to receiving radiation as part of their first course of treatment for resected stage I-II NSCLC; the primary outcome measure was overall survival...
May 2017: Annals of Surgical Oncology
Joachim Widder, Caroline Van De Wauwer, Johannes A Langendijk
No abstract text is available yet for this article.
February 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Chen Qiu, Guanghui Wang, Jun Xu, Lixuan Cui, Wei Dong, Yang Ni, Xiao Qu, Jiajun Du
OBJECTIVE: The aim of our study was to compare the operative characteristics and long term survival for elderly patients with stage I non-small cell lung cancer (NSCLC) who underwent sublobectomy versus lobectomy. METHODS: We identified 245 consecutive elderly patients (≥65y) with pathologic stage I NSCLC who underwent lobectomy or sublobectomy at our institution between 2006 and 2012, and assessed the operative characteristics, recurrence, and survival differences between these approaches...
January 2017: International Journal of Surgery
Quanxing Liu, Hongmei Wang, Dong Zhou, Xufeng Deng, Jiaxin Min, Jigang Dai
BACKGROUND: Although lobectomy has long been considered the standard procedure for Stage I nonsmall cell lung cancer (NSCLC), the selection of sublobectomy for Stage I NSCLC remains controversial. Amidst growing enthusiasm for minimally invasive surgery, the comparison of clinical outcomes after thoracoscopic sublobectomy versus thoracoscopic lobectomy may be of immense value. OBJECTIVE: The present study aimed to compare the overall survival (OS) and disease-free survival (DFS) outcomes of patients who underwent thoracoscopic sublobectomy with those who underwent thoracoscopic lobectomy for Stage I NSCLC...
April 2016: Journal of Cancer Research and Therapeutics
Jun Wang, Hui Zhao
With advances in medical technology, theproportion of early-stage lung cancerhas been growing. Conforming to the trend of individualized treatment, sublobar resection for early stage lung cancer has been considered more valuable than ever before. Currently, there were still confilictions about the oncological validity of sublobar resection comparing with lobectomy for lung cancer. We reviewed the study status of the following contentious issues: the evidence based medicine, the indications of wedge resection or segmentectomy, the weight of tumor diameter and margin distance, and the choices for the elderly...
June 20, 2016: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Deruo Liu, Zhenrong Zhang
With the widely application of chest computed tomography (CT) and gradual generalization of lung cancer screening project for high risk populations, more and more "tiny lung cancers" were identified. Due to the difficulty in intraoperative orientation, their less aggressiveness, and excellent short/long term prognosis, the 'tiny lung cancers' posed new challenges for the surgery in the treatment of lung cancer. In this review, theirfore, we focused on these challenges and presented the progress in lung cancer screening, orientation of lung nodules, lobectomy and sublobectomy, and lymph node dissection...
June 20, 2016: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Yutian Lai, Heng Du, Xin Wang, Cheng Shen, Jian Huang, Weiming Li, Guowei Che
To investigate the association between the clinical characteristics and clinical modes of surgically treated lung cancer patients, we conducted a retrospective study with 1097 lung cancer patients receiving pulmonary resection between 2012 and 2013.A physical examination or screening (PES) group (n = 267) and a symptomatic (SY) group (n = 830) were established depending on the new clinical mode (sequence of physical examination, early detection and sequential medical treatment) and the conventional mode (hospitalization due to occurrence of relevant symptoms), respectively...
January 2016: Medicine (Baltimore)
Gening Jiang, Dong Xie
The incidence of ground-glass opacity (GGO)-dominant lung cancer is rising in China. The review is focused on the diagnosis and therapy for GGO-dominant lung cancer. CT screening in high-risk groups is recommended for early diagnosis of GGO-dominant lung cancer. The early diagnosis of GGO-dominant lung cancer depends on dynamic observation on the chest CT. Non-surgical biopsy or PET/CT has limited diagnostic value in GGO-dominant lung cancer. Video-assisted Thoracoscopic resection (VATS) is the mainstream treatment for GGO-dominant lung cancer...
October 1, 2015: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
Ju-Wei Mu, Shu-Geng Gao, Qi Xue, Jun Zhao, Ning Li, Kun Yang, Kai Su, Zhu-Yang Yuan, Jie He
BACKGROUND: Both uniportal and triportal thoracoscopic lobectomy and sublobectomy are feasible for early-stage non-small cell lung cancer (NSCLC). The aim of this study was to compare the perioperative outcomes of uniportal and triportal thoracoscopic lobectomy and sublobectomy for early-stage NSCLC. METHODS: A total of 405 patients with lung lesions underwent thoracoscopic lobectomy or sublobectomy through a uniportal or triportal procedure in approximately 7-month period (From November 2014 to May 2015)...
October 20, 2015: Chinese Medical Journal
Hui Zhang, Yang Shen-Tu
No abstract text is available yet for this article.
September 20, 2015: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Hiromitsu Domen, Kichizo Kaga, Yasuhiro Hida, Naotake Honma, Reiko Kubota, Yuki Yagi, Yoshiro Matsui
BACKGROUND: According to the aging in Japan, surgery of lung cancer with cardiovascular disease is increasing. Among them, the merger of the heart and large blood vessel disease would be expected to be directly linked to the perioperative management. MATERIALS AND METHODS: We conducted a retrospective analysis of 1,005 patients who had undergone surgical resection of primary lung adenocarcinoma between January 1997 and June 2014 at Hokkaido University Hospital. Among them, 81 patients had more than one cardiovascular disease...
April 2015: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Yang Zhang, Yihua Sun, Rui Wang, Ting Ye, Yiliang Zhang, Haiquan Chen
BACKGROUND: Survival difference following lobectomy, segmentectomy, and wedge resection in stage I non-small cell lung cancer (NSCLC) and its subgroups remains undetermined. METHODS: We systemically searched published articles comparing recurrence-free survival (RFS), overall survival (OS), or cancer-specific survival (CSS) between lobectomy and limited resection or between segmentectomy and wedge resection. RESULTS: A total of 42 studies published from 1980 to 2014 enrolling 21,926 patients were included in this meta-analysis...
March 2015: Journal of Surgical Oncology
Yaxin Liu, Cheng Huang, Hongsheng Liu, Yeye Chen, Shanqing Li
BACKGROUND: Although lobectomy is considered the standard surgical treatment for the majority of patients with non-small-cell lung cancer (NSCLC), the operation project for patients with stage IA NSCLC (T1a, tumor diameter≤2 cm) remains controversial. Sublobectomy is appropriate only in certain patients as many doctors consider it to be overtreatment. We evaluated the five-year overall survival rate of sublobectomy and lobectomy for stage IA NSCLC (T1a, tumor diameter≤2 cm) through a meta-analysis...
2014: World Journal of Surgical Oncology
Yuanda Cheng, Chunfang Zhang
With the aging of the population, the proportion of elderly lung cancer is increasing. More than ten years, lobectomy with mediastinal lymph node dissection has been the standard surgery for stage I non-small cell lung cancer (NSCLC). However, recent studies found that sublobectomy could get the same long-term outcome with the lobectomy for elderly clinical stage I NSCLC and more normal lung tissue could be retained. It becomes controversial again about the standard surgery of stage I NSCLC at present. Elderly stage I NSCLC is a special group, who often can not tolerate thoracotomy because of the poor body function and some comorbidities, but the thoracoscopic surgery and the stereotactic radiotherapy technology (STRT) supply them more options...
December 2011: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
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