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Recurrent pericarditis

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https://www.readbyqxmd.com/read/27894950/untying-the-gordian-knot-of-pericardial-diseases-a-pragmatic-approach
#1
REVIEW
George Lazaros, Massimo Imazio, Antonio Brucato, Dimitrios Tousoulis
Pericardial disorders constitute a relatively common cause of heart disease. Although acute pericarditis, and especially the idiopathic forms which are the most prevalent, is considered a benign disease overall, it's short and long term complications, namely recurrent pericarditis, cardiac tamponade and constrictive pericarditis constitute a matter of concern in the medical community. In recent years several clinical trials contributed to redefine our traditional approach to pericardial diseases. In this review we provide the most recent evidence concerning diagnosis, treatment modalities and short and long-term prognosis of the most common pericardial disorders...
November 25, 2016: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/27884251/complicated-pericarditis-understanding-risk-factors-and-pathophysiology-to%C3%A2-inform%C3%A2-imaging-and-treatment
#2
REVIEW
Paul C Cremer, Arnav Kumar, Apostolos Kontzias, Carmela D Tan, E Rene Rodriguez, Massimo Imazio, Allan L Klein
Most patients with acute pericarditis have a benign course and a good prognosis. However, a minority of patients develop complicated pericarditis, and the care of these patients is the focus of this review. Specifically, we address risk factors, multimodality imaging, pathophysiology, and novel treatments. The authors conclude that: 1) early high-dose corticosteroids, a lack of colchicine, and an elevated high-sensitivity C-reactive protein are associated with the development of complicated pericarditis; 2) in select cases, cardiovascular magnetic resonance imaging may aid in the assessment of pericardial inflammation and constriction; 3) given phenotypic similarities between recurrent idiopathic pericarditis and periodic fever syndromes, disorders of the inflammasome may contribute to relapsing attacks; and 4) therapies that target the inflammasome may lead to more durable remission and resolution...
November 29, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27864249/positive-predictive-value-of-cardiovascular-diagnoses-in-the-danish-national-patient-registry-a-validation-study
#3
Jens Sundbøll, Kasper Adelborg, Troels Munch, Trine Frøslev, Henrik Toft Sørensen, Hans Erik Bøtker, Morten Schmidt
OBJECTIVE: The majority of cardiovascular diagnoses in the Danish National Patient Registry (DNPR) remain to be validated despite extensive use in epidemiological research. We therefore examined the positive predictive value (PPV) of cardiovascular diagnoses in the DNPR. DESIGN: Population-based validation study. SETTING: 1 university hospital and 2 regional hospitals in the Central Denmark Region, 2010-2012. PARTICIPANTS: For each cardiovascular diagnosis, up to 100 patients from participating hospitals were randomly sampled during the study period using the DNPR...
November 18, 2016: BMJ Open
https://www.readbyqxmd.com/read/27825009/effect-of-anakinra-on-recurrent-pericarditis-among-patients-with-colchicine-resistance-and-corticosteroid-dependence-the-airtrip-randomized-clinical-trial
#4
Antonio Brucato, Massimo Imazio, Marco Gattorno, George Lazaros, Silvia Maestroni, Mara Carraro, Martina Finetti, Davide Cumetti, Alessandra Carobbio, Nicolino Ruperto, Renzo Marcolongo, Monia Lorini, Alessandro Rimini, Anna Valenti, Gian Luca Erre, Maria Pia Sormani, Riccardo Belli, Fiorenzo Gaita, Alberto Martini
Importance: Anakinra, an interleukin 1β recombinant receptor antagonist, may have potential to treat colchicine-resistant and corticosteroid-dependent recurrent pericarditis. Objective: To determine the efficacy of anakinra for colchicine-resistant and corticosteroid-dependent recurrent pericarditis. Design, Setting, and Participants: The Anakinra-Treatment of Recurrent Idiopathic Pericarditis (AIRTRIP) double-blind, placebo-controlled, randomized withdrawal trial (open label with anakinra followed by a double-blind withdrawal step with anakinra or placebo until recurrent pericarditis occurred) conducted among 21 consecutive patients enrolled at 3 Italian referral centers between June and November 2014 (end of follow-up, October 2015)...
November 8, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27762219/coxiella-burnetii-chronic-pericarditis-a-case-report
#5
I Ivić, I Božić, D Ledina
Coxiella burnetii is capable of causing a variety of acute and chronic infections. We present a case of pericarditis with serologically confirmed chronic C. burnetii infection. This case report emphasises the justification of serological testing for chronic C. burnetii infection in patients with prolonged or recurrent pericarditis, particularly in countries endemic for C. burnetii infection.
October 2016: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/27747691/hypersensitivity-eosinophilic-myocarditis-in-a-patient-receiving-multiple-drug-therapy-challenges-in-diagnosis-and-defining-the-aetiology
#6
Dario Gulin, Jozica Sikic, Jasna Cerkez Habek, Sandra Jerkovic Gulin, Edvard Galic
Eosinophilic myocarditis (EM) is a rare and potentially fatal disease if left untreated. Because the disease can have a delayed presentation and can appear even after 2 years, its underlying causes often remain unknown. We report the case of a 63-year-old man with an atypical clinical presentation of hypersensitive EM and significant coronary artery disease, which was confirmed through coronary angiography. The patient was treated with hydrochlorothiazide (12.5 mg once daily for 2 years) and budesonide/formoterol (160/4...
December 2016: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/27725173/recurrent-pericarditis
#7
Massimo Imazio, Elena Gribaudo, Fiorenzo Gaita
Recurrent pericarditis is the most common and troublesome complication of pericarditis affecting 20 to 50% of patients. Its pathogenesis is often presumed to be immune-mediated, but additional investigations are needed to clarify the pathogenesis in order to develop etiology-oriented therapies. Imaging with Computed Tomography and especially Cardiac Magnetic Resonance holds promise to help in the identification of more difficult cases and improve their management. Refractory recurrent pericarditis with corticosteroid dependence and colchicine resistance remain still an unsolved issue in search of new therapies, although old drugs such as azathioprine, intravenous immunoglobulins, and biological agents seem promising, but new randomized clinical trials are needed to confirm their role...
October 7, 2016: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/27659857/recurrent-pericarditis-as-the-presenting-form-of-adult-still-s-disease
#8
Irina Jara Calabuig, Ruth María Sánchez Soriano, Tomás Francisco Marco Domingo, Cristina Pérez Ortiz, Antonio Javier Chamorro Fernández, Carlos Israel Chamorro Fernández
No abstract text is available yet for this article.
September 19, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27631124/neisseria-meningitidis-presenting-as-acute-abdomen-and-recurrent-reactive-pericarditis
#9
Karolina Akinosoglou, Angelos Alexopoulos, Nikolaos Koutsogiannis, Charalampos Gogos, Aleksandra Lekkou
Meningococcal meningitis is a well established potential fatal infection characterized by fever, headache, petechial rash, and vomiting in the majority of cases. However, protean manifestations including abdominal pain, sore throat, diarrhea and cough, even though rare, should not be overlooked. Similarly, although disseminated infection could potentially involve various organ-targets, secondary immune related complications including joints or pericardium should be dealt with caution, since they remain unresponsive to appropriate antibiotic regimens...
September 12, 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27580061/colchicine-for-prevention-and-treatment-of-cardiac-diseases-a-meta-analysis
#10
Nikos Papageorgiou, Alexandros Briasoulis, George Lazaros, Massimo Imazio, Dimitris Tousoulis
AIMS: Colchicine has been suggested to be beneficial in preventing recurrent pericarditis. The goal of this study was to review all randomized controlled trials that assess the use of colchicine for the prevention and treatment of cardiac diseases. METHODS: We performed a meta-analysis of the effects of colchicine on pericarditis, post-pericardiotomy syndrome and post-procedural atrial fibrillation recurrence, in-stent restenosis, gastrointestinal adverse effects and treatment discontinuation rates...
August 31, 2016: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/27571913/molecular-diagnosis-of-opportunistic-pericardial-infection-in-a-patient-treated-with-adalimumab-the-role-of-next-generation-sequencing
#11
Stefano Poli, Manola Comar, Roberto Luzzati, Gianfranco Sinagra
Biological immune-modulator drugs, especially inhibitors of tumor necrosis factor-α, are frequently encountered in modern clinical practice and opportunistic infections are therefore a common concern. Infective pericarditis has been described as a complication of these treatments with possible life-threatening consequences. In similar cases cultures may isolate multiple opportunistic bacteria from the pericardial fluid without specific identification of the responsible germ, representing a problem for targeted antibiotic therapy...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27562837/natural-history-and-life-threatening-complications-in-myhre-syndrome-and-review-of-the-literature
#12
Livia Garavelli, Ilenia Maini, Federica Baccilieri, Ivan Ivanovski, Marzia Pollazzon, Simonetta Rosato, Lorenzo Iughetti, Sheila Unger, Andrea Superti-Furga, Marco Tartaglia
UNLABELLED: Myhre syndrome (OMIM 139210) is a rare developmental disorder inherited as an autosomal dominant trait and caused by a narrow spectrum of missense mutations in the SMAD4 gene. The condition features characteristic face, short stature, skeletal anomalies, muscle pseudohypertrophy, restricted joint mobility, stiff and thick skin, and variable intellectual disability. While most of the clinical features manifest during childhood, the diagnosis may be challenging during the first years of life...
October 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27522122/the-minimally-invasive-repair-of-pectus-excavatum-using-a-subxiphoid-incision
#13
Joanna L Gould, Ronald J Sharp, Shawn David St Peter, Charles L Snyder, David Juang, Pablo Aguayo, Jason D Fraser, George W Holcomb
Purpose Several surgeons have documented outcomes following the Nuss operation. Most reports have described the use of thoracoscopy to avoid cardiac injury. Since 1999, our group has utilized a subxiphoid incision, allowing insertion of the surgeon's finger into the substernal space to help guide the bar across the mediastinum. Our initial experience has been reported and we are now reporting our entire experience to date. Methods A retrospective review was conducted on all patients who underwent pectus excavatum repair using a subxiphoid incision from December, 1999 to September, 2015...
August 14, 2016: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27517082/surgical-management-of-massive-pericardial-effusion-and-predictors-for-development-of-constrictive-pericarditis-in-a-resource-limited-setting
#14
Emeka B Kesieme, Peter O Okokhere, Christopher Ojemiega Iruolagbe, Angela Odike, Clifford Owobu, Theophilus Akhigbe
Background. The diagnosis and treatment of massive pericardial effusion and cardiac tamponade have evolved over the years with a tendency towards a more comprehensive diagnostic workup and less traumatic intervention. Method. We reviewed and analysed the data of 32 consecutive patients who underwent surgery on account of massive pericardial effusion and cardiac tamponade in a semiurban university hospital in Nigeria from February 2010 to February 2016. Results. The majority of patients (34.4%) were between 31 and 40 years...
2016: Advances in Medicine
https://www.readbyqxmd.com/read/27503940/successful-treatment-of-recurrent-pleural-and-pericardial-effusions-with-tocilizumab-in-a-patient-with-systemic-lupus-erythematous
#15
Vanessa Ocampo, Derek Haaland, K Legault, Shika Mittoo, Emily Aitken
A 22-year-old Caucasian man presented to hospital with pleuritic chest pain. He had had a history of a sun-sensitive rash a year prior. Workup revealed normal cardiac enzymes and chest X-ray. However, electrocardiogram revealed ST elevation and PR depression, and echocardiogram revealed a slight pericardial effusion without other findings. A diagnosis of pericarditis was made. Subsequently, he was found to be positive for antinuclear antibodies (ANAs), as well as antibodies to SSA, SSB and double-stranded DNA; C3 was low, and C4 was undetectable...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27499994/a-30-year-old-female-beh%C3%A3-et-s-disease-patient-with-recurrent-pleural-and-pericardial-effusion-and-elevated-adenosine-deaminase-levels-case-report
#16
Joon Young Choi, Sung-Hwan Kim, Seung-Ki Kwok, Jung Im Jung, Kyo-Young Lee, Tae-Jung Kim, Ji Young Kang
Behçet's disease is a systemic disease which may involve various organs. We describe a case of a patient diagnosed as pleuropericardial involvement of Behçet's disease. A 30-year-old woman visited our clinic presented with left pleuritic chest pain for s days. She had been diagnosed as Behçet's disease and admitted to our clinic due to pericardial and pleural effusion repeatedly in past two years. In the previous studies, effusion analysis revealed to be lympho-dominant exudate with high adenosine deaminase level...
July 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27486311/simultaneous-surgery-in-patients-with-both-cardiac-and-noncardiac-diseases
#17
Yang Yang, Feng Xiao, Jin Wang, Bo Song, Xi-Hui Li, Jian Li, Zhi-Song He, Huan Zhang, Ling Yin
BACKGROUND: To investigate the possibility and feasibility of simultaneous cardiac and noncardiac surgery. METHODS: From August 2000 to March 2015, 64 patients suffering from cardiac and noncardiac diseases have been treated by simultaneous surgeries. RESULTS: Two patients died after operations in hospital; thus, the hospital mortality rate was 3.1%. One patient with coronary heart disease, acute myocardial infarction, and a recurrence of bladder cancer accepted emergency simultaneous coronary artery bypass grafting (CABG), bladder cystectomy, and ureterostomy...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27467459/recurrent-pericarditis-in-children-and-adolescents-a-multicentre-cohort-study
#18
Massimo Imazio, Antonio Brucato, Nikki Pluymaekers, Luciana Breda, Giovanni Calabri, Luca Cantarini, Rolando Cimaz, Filomena Colimodio, Fabrizia Corona, Davide Cumetti, Chiara Di Blasi Lo Cuccio, Marco Gattorno, Antonella Insalaco, Giuseppe Limongelli, Maria Giovanna Russo, Anna Valenti, Yaron Finkelstein, Alberto Martini
OBJECTIVE: Limited data are available about recurrent pericarditis in children. We sought to explore contemporary causes, characteristics, therapies and outcomes of recurrent pericarditis in paediatric patients. METHODS: A multicentre (eight sites) cohort study of 110 consecutive cases of paediatric patients with at least two recurrences of pericarditis over an 11-year period (2000-2010) [median 13 years, interquartile range (IQR) 5, 69 boys]. RESULTS: Recurrences were idiopathic or viral in 89...
September 2016: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/27450172/-magnetic-resonance-guided-treatment-for-recurrent-pericarditis
#19
Andrea Izquierdo Marquisa, Cecilia Caso, Francesca Mitjavila Villero, Eduard Claver I Garrido
No abstract text is available yet for this article.
July 20, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/27440768/bet-1-safety-and-efficacy-of-colchicine-as-stand-alone-therapy-for-the-prevention-of-recurrent-pericarditis
#20
Andrew Manspeaker, Rebecca Andrews-Dickert
A short cut review was carried out looking for evidence of the benefits of using colchicine as a single therapy for acute pericarditis. A literature search was performed but no papers were found to provide evidence of the efficacy of colchicine without the concurrent use of Non-steriodal anti-inflammatory drugs (NSAIDs) for this condition.
August 2016: Emergency Medicine Journal: EMJ
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