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Recurrent pericarditis

I Ivić, I Božić, D Ledina
Coxiella burnetii is capable of causing a variety of acute and chronic infections. We present a case of pericarditis with serologically confirmed chronic C. burnetii infection. This case report emphasises the justification of serological testing for chronic C. burnetii infection in patients with prolonged or recurrent pericarditis, particularly in countries endemic for C. burnetii infection.
October 2016: Netherlands Journal of Medicine
Dario Gulin, Jozica Sikic, Jasna Cerkez Habek, Sandra Jerkovic Gulin, Edvard Galic
Eosinophilic myocarditis (EM) is a rare and potentially fatal disease if left untreated. Because the disease can have a delayed presentation and can appear even after 2 years, its underlying causes often remain unknown. We report the case of a 63-year-old man with an atypical clinical presentation of hypersensitive EM and significant coronary artery disease, which was confirmed through coronary angiography. The patient was treated with hydrochlorothiazide (12.5 mg once daily for 2 years) and budesonide/formoterol (160/4...
December 2016: Drug Saf Case Rep
Massimo Imazio, Elena Gribaudo, Fiorenzo Gaita
Recurrent pericarditis is the most common and troublesome complication of pericarditis affecting 20 to 50% of patients. Its pathogenesis is often presumed to be immune-mediated, but additional investigations are needed to clarify the pathogenesis in order to develop etiology-oriented therapies. Imaging with Computed Tomography and especially Cardiac Magnetic Resonance holds promise to help in the identification of more difficult cases and improve their management. Refractory recurrent pericarditis with corticosteroid dependence and colchicine resistance remain still an unsolved issue in search of new therapies, although old drugs such as azathioprine, intravenous immunoglobulins, and biological agents seem promising, but new randomized clinical trials are needed to confirm their role...
October 7, 2016: Progress in Cardiovascular Diseases
Irina Jara Calabuig, Ruth María Sánchez Soriano, Tomás Francisco Marco Domingo, Cristina Pérez Ortiz, Antonio Javier Chamorro Fernández, Carlos Israel Chamorro Fernández
No abstract text is available yet for this article.
September 19, 2016: Revista Española de Cardiología
Karolina Akinosoglou, Angelos Alexopoulos, Nikolaos Koutsogiannis, Charalampos Gogos, Aleksandra Lekkou
Meningococcal meningitis is a well established potential fatal infection characterized by fever, headache, petechial rash, and vomiting in the majority of cases. However, protean manifestations including abdominal pain, sore throat, diarrhea and cough, even though rare, should not be overlooked. Similarly, although disseminated infection could potentially involve various organ-targets, secondary immune related complications including joints or pericardium should be dealt with caution, since they remain unresponsive to appropriate antibiotic regimens...
September 12, 2016: Brazilian Journal of Infectious Diseases
Nikos Papageorgiou, Alexandros Briasoulis, George Lazaros, Massimo Imazio, Dimitris Tousoulis
AIMS: Colchicine has been suggested to be beneficial in preventing recurrent pericarditis. The goal of this study was to review all randomized controlled trials that assess the use of colchicine for the prevention and treatment of cardiac diseases. METHODS: We performed a meta-analysis of the effects of colchicine on pericarditis, post-pericardiotomy syndrome and post-procedural atrial fibrillation recurrence, in-stent restenosis, gastrointestinal adverse effects and treatment discontinuation rates...
August 31, 2016: Cardiovascular Therapeutics
Stefano Poli, Manola Comar, Roberto Luzzati, Gianfranco Sinagra
Biological immune-modulator drugs, especially inhibitors of tumor necrosis factor-α, are frequently encountered in modern clinical practice and opportunistic infections are therefore a common concern. Infective pericarditis has been described as a complication of these treatments with possible life-threatening consequences. In similar cases cultures may isolate multiple opportunistic bacteria from the pericardial fluid without specific identification of the responsible germ, representing a problem for targeted antibiotic therapy...
2016: BMJ Case Reports
Livia Garavelli, Ilenia Maini, Federica Baccilieri, Ivan Ivanovski, Marzia Pollazzon, Simonetta Rosato, Lorenzo Iughetti, Sheila Unger, Andrea Superti-Furga, Marco Tartaglia
UNLABELLED: Myhre syndrome (OMIM 139210) is a rare developmental disorder inherited as an autosomal dominant trait and caused by a narrow spectrum of missense mutations in the SMAD4 gene. The condition features characteristic face, short stature, skeletal anomalies, muscle pseudohypertrophy, restricted joint mobility, stiff and thick skin, and variable intellectual disability. While most of the clinical features manifest during childhood, the diagnosis may be challenging during the first years of life...
October 2016: European Journal of Pediatrics
Joanna L Gould, Ronald J Sharp, Shawn David St Peter, Charles L Snyder, David Juang, Pablo Aguayo, Jason D Fraser, George W Holcomb
Purpose Several surgeons have documented outcomes following the Nuss operation. Most reports have described the use of thoracoscopy to avoid cardiac injury. Since 1999, our group has utilized a subxiphoid incision, allowing insertion of the surgeon's finger into the substernal space to help guide the bar across the mediastinum. Our initial experience has been reported and we are now reporting our entire experience to date. Methods A retrospective review was conducted on all patients who underwent pectus excavatum repair using a subxiphoid incision from December, 1999 to September, 2015...
August 14, 2016: European Journal of Pediatric Surgery
Emeka B Kesieme, Peter O Okokhere, Christopher Ojemiega Iruolagbe, Angela Odike, Clifford Owobu, Theophilus Akhigbe
Background. The diagnosis and treatment of massive pericardial effusion and cardiac tamponade have evolved over the years with a tendency towards a more comprehensive diagnostic workup and less traumatic intervention. Method. We reviewed and analysed the data of 32 consecutive patients who underwent surgery on account of massive pericardial effusion and cardiac tamponade in a semiurban university hospital in Nigeria from February 2010 to February 2016. Results. The majority of patients (34.4%) were between 31 and 40 years...
2016: Advances in Medicine
Vanessa Ocampo, Derek Haaland, K Legault, Shika Mittoo, Emily Aitken
A 22-year-old Caucasian man presented to hospital with pleuritic chest pain. He had had a history of a sun-sensitive rash a year prior. Workup revealed normal cardiac enzymes and chest X-ray. However, electrocardiogram revealed ST elevation and PR depression, and echocardiogram revealed a slight pericardial effusion without other findings. A diagnosis of pericarditis was made. Subsequently, he was found to be positive for antinuclear antibodies (ANAs), as well as antibodies to SSA, SSB and double-stranded DNA; C3 was low, and C4 was undetectable...
2016: BMJ Case Reports
Joon Young Choi, Sung-Hwan Kim, Seung-Ki Kwok, Jung Im Jung, Kyo-Young Lee, Tae-Jung Kim, Ji Young Kang
Behçet's disease is a systemic disease which may involve various organs. We describe a case of a patient diagnosed as pleuropericardial involvement of Behçet's disease. A 30-year-old woman visited our clinic presented with left pleuritic chest pain for s days. She had been diagnosed as Behçet's disease and admitted to our clinic due to pericardial and pleural effusion repeatedly in past two years. In the previous studies, effusion analysis revealed to be lympho-dominant exudate with high adenosine deaminase level...
July 2016: Journal of Thoracic Disease
Yang Yang, Feng Xiao, Jin Wang, Bo Song, Xi-Hui Li, Jian Li, Zhi-Song He, Huan Zhang, Ling Yin
BACKGROUND: To investigate the possibility and feasibility of simultaneous cardiac and noncardiac surgery. METHODS: From August 2000 to March 2015, 64 patients suffering from cardiac and noncardiac diseases have been treated by simultaneous surgeries. RESULTS: Two patients died after operations in hospital; thus, the hospital mortality rate was 3.1%. One patient with coronary heart disease, acute myocardial infarction, and a recurrence of bladder cancer accepted emergency simultaneous coronary artery bypass grafting (CABG), bladder cystectomy, and ureterostomy...
2016: Patient Preference and Adherence
Massimo Imazio, Antonio Brucato, Nikki Pluymaekers, Luciana Breda, Giovanni Calabri, Luca Cantarini, Rolando Cimaz, Filomena Colimodio, Fabrizia Corona, Davide Cumetti, Chiara Di Blasi Lo Cuccio, Marco Gattorno, Antonella Insalaco, Giuseppe Limongelli, Maria Giovanna Russo, Anna Valenti, Yaron Finkelstein, Alberto Martini
OBJECTIVE: Limited data are available about recurrent pericarditis in children. We sought to explore contemporary causes, characteristics, therapies and outcomes of recurrent pericarditis in paediatric patients. METHODS: A multicentre (eight sites) cohort study of 110 consecutive cases of paediatric patients with at least two recurrences of pericarditis over an 11-year period (2000-2010) [median 13 years, interquartile range (IQR) 5, 69 boys]. RESULTS: Recurrences were idiopathic or viral in 89...
September 2016: Journal of Cardiovascular Medicine
Andrea Izquierdo Marquisa, Cecilia Caso, Francesca Mitjavila Villero, Eduard Claver I Garrido
No abstract text is available yet for this article.
July 20, 2016: Medicina Clínica
Andrew Manspeaker, Rebecca Andrews-Dickert
A short cut review was carried out looking for evidence of the benefits of using colchicine as a single therapy for acute pericarditis. A literature search was performed but no papers were found to provide evidence of the efficacy of colchicine without the concurrent use of Non-steriodal anti-inflammatory drugs (NSAIDs) for this condition.
August 2016: Emergency Medicine Journal: EMJ
Farhan Ashraf, Fady Marmoush, Muhammad Ismail Shafi, Ashish Shah
Drug-induced pericarditis is a well-described cardiac pathology that can result from a variety of medications; however, interferon-mediated pericarditis is extremely rare. We present a case of a young female with recurrent pericarditis due to interferon therapy. The role of interferon in adjuvant chemotherapy is well known and yields good effect, but this case highlights the very uncommon phenomena of interferon induced pericarditis and the significant distress it can cause.
2016: Case Reports in Cardiology
Syed Raza Shah, Richard Alweis, Syed Arbab Shah, Mohammad Hussham Arshad, Adil Al-Karim Manji, Arham Amir Arfeen, Maheen Javed, Syed Muhammad Shujauddin, Rida Irfan, Sakina Shabbir, Shehryar Shaikh
Colchicine, extracted from the colchicum autumnale plant, used by the ancient Greeks more than 20 centuries ago, is one of the most ancient drugs still prescribed even today. The major mechanism of action is binding to microtubules thereby interfering with mitosis and subsequent modulation of polymorphonuclear leukocyte function. Colchicine has long been of interest in the treatment of cardiovascular disease; however, its efficacy and safety profile for specific conditions have been variably established in the literature...
2016: Journal of Community Hospital Internal Medicine Perspectives
Ming-Xuan Wang, Xiao-Long Deng, Bing-Yao Mu, Yong-Jing Cheng, Ying-Juan Chen, Qian Wang, Jia Huang, Rong-Wei Zhou, Ci-Bo Huang
Randomized, controlled trials (RCTs) have assessed the effect of colchicine therapy in prevention of pericardial effusion (PE) and atrial fibrillation (AF). However, the effects are still inconclusive. PubMed, Cochrane Library, Google Scholar, and EMBASE database were searched. Primary outcome was the risk of PE and AF. Ten RCTs with 1981 patients and a mean follow-up of 12.6 months were included. Colchicine therapy was not associated with a significantly lower risk of post-operative PE (RR, 0.89; 95 % CI 0...
September 2016: Internal and Emergency Medicine
Mariana Mihăilă, V Herlea, Camelia Dobrea, Ioana Lupescu, Gina Rusu Munteanu, Grethi Chiriac, L Micu, R Serescu, I Copaci
We present the case of a 76 year old female patient admitted in the Department of Cardiology for physical asthenia, profuse sweating and dyspnea with orthopnea for about one month. Clinical and paraclinical assessments performed at admission confirmed the diagnosis of cardiac tamponade. Surgical intervention was performed and 400 mL of clear effusion were drained. Post-operative evolution was marked by recurrence of symptoms, requiring after 3 weeks a new drainage of 600 mL of clear effusion, and biopsy of the pericardium was performed...
April 2016: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
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