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https://www.readbyqxmd.com/read/30546872/atypical-type-of-familial-mediterranean-fever-an-underdiagnosed-cause-of-chronic-aseptic-meningitis
#1
Masayuki Sugie, Takahiro Ouchi, Dai Kishida, Shunji Yasaki
We report an atypical case of familial Mediterranean fever (FMF) concomitant with chronic aseptic meningitis. The patient experienced fever, abdominal and back pain because of serositis, and headache because of aseptic meningitis for 4 weeks. Blood examinations revealed increased white blood cells and serum amyloid A level. Medications, including steroids, did not improve his symptoms. However, the patient experienced immediate relief after the administration of colchicine. We diagnosed him as having atypical FMF based on the symptoms, especially positive response to colchicine, and heterozygous mutations on exon2 and 5 (E148Q/S503C) in MEFV gene...
November 2018: Neurology and Clinical Neuroscience
https://www.readbyqxmd.com/read/30546813/posterior-fossa-choroid-plexus-papilloma-with-focal-ependymal-differentiation-in-an-adult-patient-a-case-report-and-literature-review
#2
Shu Matsushita, Taro Shimono, Takeo Goto, Satoshi Doishita, Yuko Kuwae, Yukio Miki
Choroid plexus papillomas (CPPs) are rare neoplasms classified as World Health Organization grade I tumors. CPPs containing other tissues have occasionally been documented in the literature. However, few of these previous reports have provided clinical and radiological information. We herein report a case of a posterior fossa CPP with focal ependymal differentiation in a 42-year-old woman who presented with a 6-month history of progressive headache. Preoperative radiological images showed a hypervascular tumor protruding into the left foramen of Luschka with perilesional edema...
March 2019: Radiology Case Reports
https://www.readbyqxmd.com/read/30546500/fragranced-consumer-products-effects-on-autistic-adults-in-the-united-states-australia-and-united-kingdom
#3
Anne Steinemann
Fragranced consumer products, such as cleaning supplies, air fresheners, and personal care products, can have adverse effects on both air quality and health. This study investigates the effects of fragranced products on autistic individuals ages 18-65 in the United States, Australia, and United Kingdom. Nationally representative population surveys ( n  = 1137; 1098; 1100) found that, across the three countries, 4.3% of adults ( n  = 142) report medically diagnosed autism (2.3%), an autism spectrum disorder (2...
2018: Air Quality, Atmosphere, & Health
https://www.readbyqxmd.com/read/30546228/study-of-stress-induced-temporomandibular-disorders-among-dental-students-an-institutional-study
#4
Vikram Ahuja, Vikash Ranjan, Deepak Passi, Rashi Jaiswal
Aim and Objectives: The aim and objectives of this study are to investigate the various types of stress-inducing factors, most prevalent etiological factor and to determine the correlation between stress and temporomandibular disorders (TMDs) in Dental students in Modinagar, Ghaziabad, Uttar Pradesh. Materials and Methods: A sample of 450 students were selected for the study divided into two groups of undergraduate (UG) and postgraduate (PG) students further subdivided into UG (1st , 2nd , 3rd , and 4th , interns) and PG (1st , 2nd , 3rd year)...
July 2018: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/30545801/more-than-just-sleeping-in-a-late-timing-of-sleep-is-associated-with-health-problems-and-unhealthy-behaviours-in-adolescents
#5
Geneviève Gariépy, Isabelle Doré, Ross D Whitehead, Frank J Elgar
OBJECTIVE: New research suggests that the timing of sleep, or chronotype, affects the mental well-being of adolescents, however evidence of its links to physical health is limited. We investigated the associations between chronotype and various health outcomes and behaviours in a national sample of Canadian adolescents. METHODS: Data were from the 2014 Canadian Health Behaviour in School-Aged Children survey (29,470 students; ages 10-18). Chronotype was estimated using the midpoint of sleep on weekends, corrected for catch-up sleep...
November 20, 2018: Sleep Medicine
https://www.readbyqxmd.com/read/30545719/a-novel-notch3-gene-mutation-in-a-polish-cadasil-family
#6
Karolina Machowska-Sempruch, Anna Bajer-Czajkowska, Karol Makarewicz, Karolina Zaryczańska, Adam Koryzma, Przemysław Nowacki
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a genetically determined disease of the cerebral vessels, characterized by recurrent ischemic strokes, dementia, and degeneration of the cerebral white matter. The condition is caused by a mutation in the NOTCH3 gene, whose product plays a great role in the development and physiology of the cardiovascular system. Magnetic resonance imaging reveals multiple hyperintensive lesions of the white matter in the T2-weighted images also in asymptomatic carriers of CADASIL and can be detected even 10-15 years prior to clinical signs...
December 10, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30545081/pediatric-integrative-medicine-in-academia-stanford-children-s-experience
#7
REVIEW
Gautam Ramesh, Dana Gerstbacher, Jenna Arruda, Brenda Golianu, John Mark, Ann Ming Yeh
Pediatric integrative medicine is an emerging field which, to date, has not been described in detail in academic medical centers in the United States. Early research of pediatric integrative medicine modalities shows promise for the treatment of common pediatric conditions such as irritable bowel syndrome, acute and chronic pain, headache, and allergy, among others. In light of the growing prevalence of pediatric illnesses and patient complexity, it is crucial to emphasize the patient's overall well-being. As academic centers around the world start to develop pediatric integrative medicine programs, the aim of this manuscript is to briefly highlight evidence of effective integrative treatments in pediatric subspecialties, to describe the establishment of our integrative medicine program, to summarize its early efforts, and to discuss potential barriers and keys to success...
December 12, 2018: Children
https://www.readbyqxmd.com/read/30544405/mesalazine-treatment-causing-resolution-of-intracranial-hypertension-secondary-to-ulcerative-colitis-a-case-report
#8
Raoul Kanav Khanna, Rabih Hage, Alexandre Hage, Vanessa Polin, Thomas Sené, Catherine Vignal-Clermont
RATIONALE: The association between intracranial hypertension (ICH) and ulcerative colitis (UC) is rare. We report the unusual case of a male patient with UC and ICH in whom both conditions resolved with mesalazine therapy. PATIENT CONCERNS: A 48-year-old Caucasian man presented to our department in June 2016 for decreased vision, transient visual obscuration, pulsatile tinnitus and headaches of 7 months duration. Bilateral optic disc swelling was found at fundus examination...
December 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30544360/neuroendoscopic-fenestration-of-glioependymal-cysts-to-the-ventricle-report-of-3-cases
#9
(no author information available yet)
Glioependymal cysts are rare congenital lesions of the central nervous system. Reported surgical treatments of these lesions have varied and yielded mixed results, and the optimal surgical strategy is still controversial. The authors here report the clinical and surgical outcomes for three adult patients successfully treated with neuroendoscopic fenestration into the ventricular system. The patients had presented with symptomatic glioependymal cysts in the period from 2013 to 2016 at the authors' institution...
November 1, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/30544357/surgical-outcomes-after-reoperation-for-recurrent-non-skull-base-meningiomas
#10
(no author information available yet)
OBJECTIVERecurrent meningiomas are primarily managed with radiation therapy or repeat resection. Surgical morbidity after reoperation for recurrent meningiomas is poorly understood. Thus, the objective of this study was to report surgical outcomes after reoperation for recurrent non-skull base meningiomas.METHODSA retrospective review of patients was performed. Inclusion criteria were patients with recurrent meningioma who had prior resection and supratentorial non-skull base location. Univariate and multivariate logistic regression and recursive partitioning analysis were used to identify risk factors for surgical complications...
November 1, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/30543645/epidemiology-of-lumbar-punctures-in-hospitalized-patients-in-the-united-states
#11
Adrienne Vickers, John P Donnelly, Justin Xavier Moore, Scott R Barnum, Theresa N Schein, Henry E Wang
OBJECTIVES: Lumbar puncture (LP) is an important technique for assessing and treating neurological symptoms. The objective of this study was to describe the characteristics of diagnostic lumbar punctures performed on hospitalized patients in the United States. METHODS: We analyzed data from the 2010 National Inpatient Sample (NIS) and the National Emergency Department Survey (NEDS). We included patients treated in the Emergency Department (ED) as well as those admitted to an inpatient bed through the ED...
2018: PloS One
https://www.readbyqxmd.com/read/30543536/ultrasound-guided-pulsed-radiofrequency-of-c2-dorsal-root-ganglion-as-adjuvant-treatment-for-chronic-headache-disorders-a-case-report
#12
Oluseyi Fadayomi, Mark C Kendall, Antoun Nader
Cluster headaches are characterized by unilateral sudden onset of intense, brief, sharp pain along the side of the face around the eye. Patients often can have symptoms that are resistant to medications, nerve blocks, and surgical treatments. There is increasing evidence of anatomical and functional connections between the trigeminal and occipital nerves. We present a patient with cluster headache presenting with chronic ipsilateral facial pain with nasal congestion and left eye pain who achieved sustained pain relief with an ultrasound-guided injection into the pterygopalatine fossa in conjunction with an ultrasound-guided pulsed radiofrequency ablation procedure involving the C2 dorsal root ganglion...
December 11, 2018: A&A practice
https://www.readbyqxmd.com/read/30543269/noninvasive-vagus-nerve-stimulation-in-a-primary-care-setting-effects-on-quality-of-life-and-utilization-measures-in-multimorbidity-patients-with-or-without-primary-headache
#13
Iain Strickland, Mkaya Mwamburi, Steven Davis, James C R Ward, Janet Day, Andrew T Tenaglia, Eric J Leibler, Peter S Staats
A patient audit was conducted in the UK to evaluate the impact of gammaCore use in multimorbidity patients on quality of life and healthcare resources utilization measures. A total of 233 patients were enrolled and their data was examined over a 1-year period after their gammaCore prescription. Of these patients, 132 (56%) had primary headache disorders while 101 (44%) were patients without a headache disorder (nonheadache patients). The mean age was 49 years, 169 (72%) were female, the mean number of comorbid conditions was 3...
December 2018: American Journal of Managed Care
https://www.readbyqxmd.com/read/30543268/review-of-evidence-on-noninvasive-vagus-nerve-stimulation-for-treatment-of-migraine-efficacy-safety-and-implications
#14
Mkaya Mwamburi, Andrew T Tenaglia, Eric J Leibler, Peter S Staats
GammaCore was cleared by the FDA for the acute treatment of episodic migraine and episodic cluster headache and has 5 Conformité Européenne marks. Data indicate that gammaCore treatment is both safe and effective as an acute treatment for migraine. Current reimbursement policies need to be updated based on the growing body of evidence to reflect the established status of gammaCore that is no longer experimental. GammaCore provides substantial value to patients and to payers for consideration for pay-for-performance health coverage strategies and policies...
December 2018: American Journal of Managed Care
https://www.readbyqxmd.com/read/30542965/the-evaluation-of-the-sense-of-hearing-in-patients-with-carotid-artery-stenosis-within-the-extracranial-segments
#15
Karolina Dorobisz, Tadeusz Dorobisz, Dariusz Janczak, Tomasz Krecicki
Stenosis of arteries that supplies blood to the brain is one of the main causes of ischemic stroke which is the third most common cause of deaths in Europe. Atherosclerosis of carotid and vertebral arteries is responsible for 20% of the ischemic stroke cases. Stenosis may be either asymptomatic or manifested with typical neurological symptoms including motor and sensory disturbances as well as disturbances in vision and speech. However, discrete non-specific symptoms of ischemia, including headaches and vertigo, tinnitus and hearing loss, are also quite common...
December 12, 2018: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/30542949/characteristics-and-relative-factors-of-headache-caused-by-cervicocerebral-artery-dissection
#16
Yuhan Wang, Wenchao Cheng, Yajun Lian, Jing Zhang, Yake Zheng, Yiying Hu, Yuan Chen, Shouyi Wu, Zhi Huang, Yinping Shi
OBJECTIVE: To analyze the characteristics and relative factors of headache and neck pain due to cervicocerebral artery dissection (CAD). METHODS: A total of 146 consecutive patients with CAD in Zhengzhou, China (2010-2017) were observed and registered prospectively. There were 60 (60/146) cases who complained of headache and neck pain, and we analyzed the characteristics of pain according to their clinical features. For the 130 (130/146) patients with complete clinical laboratory data, they were divided into two groups according to pain, and the relative factors of pain were analyzed...
December 12, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/30542775/pituitary-adenoma-apoplexy-associated-with-vardenafil-intake
#17
Atsuhito Uneda, Koji Hirashita, Masatoshi Yunoki, Kimihiro Yoshino, Isao Date
Vardenafil is a potent phosphodiesterase-5 (PDE-5) inhibitor used in the treatment of erectile dysfunction. Several cases of stroke related to the use of PDE-5 inhibitors have been reported. Here, we describe the case of a 51-year-old man with headache and right ophthalmoplegia subsequent to vardenafil consumption. Computed tomography and magnetic resonance imaging showed a suprasellar mass with hemorrhage suggesting pituitary apoplexy. He underwent transsphenoidal resection of the pituitary mass. Histopathology confirmed the diagnosis of a necrotic pituitary adenoma with hemorrhage...
December 12, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/30541606/efficacy-of-8-mg-lidocaine-and-2-mg-cetylpyridinium-chloride-cpc-fixed-combination-lozenges-on-sore-throat-pain-intensity-compared-with-1-mg-lidocaine-and-2-mg-cpc-fixed-combination-lozenges-in-subjects-with-sore-throat-due-to-upper-respiratory-tract-infection
#18
Frank Donath, Pascal Mallefet, Stephen Garreffa, Rowland Furcha
BACKGROUND: Lozenges containing lidocaine and cetylpyridinium chloride (CPC) are commonly used for the treatment of sore throat. The lidocaine acts locally to provide pain relief and the CPC has an antiseptic effect. Mebucaine CL, a well-established fixed-combination sore throat lozenge, contains 1 mg lidocaine and 2 mg CPC. Single-agent lozenges containing 8 mg lidocaine have also been demonstrated to be significantly superior to placebo in confirmatory pain intensity assessments...
December 12, 2018: Trials
https://www.readbyqxmd.com/read/30540895/red-ear-syndrome-perspectives-for-the-otolaryngologist
#19
Sheldon P Hersh, Joshua N Hersh
Red ear syndrome (RES) is an unusual, often unrecognized condition that has rarely been reported in the otolaryngology literature despite the presence of symptoms and associated disorders of relevance to the otolaryngologist. When present, RES may have diagnostic value when uncertainties arise in cases of sinus headache and referred otalgia. Despite the appearance of a distinctive red ear, as well as symptoms and associated disorders relating to otolaryngology, discussion of RES is generally limited to neurology-based publications...
December 2018: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/30540124/primary-malignant-tumors-of-the-adrenal-glands
#20
Madson Q Almeida, Joao Evangelista Bezerra-Neto, Berenice B Mendonça, Ana Claudia Latronico, Maria Candida B V Fragoso
Malignancy must be considered in the management of adrenal lesions, including those incidentally identified on imaging studies. Adrenocortical carcinomas (ACCs) are rare tumors with an estimated annual incidence of 0.7-2 cases per year and a worldwide prevalence of 4-12 cases per million/year. However, a much higher incidence of these tumors (>15 times) has been demonstrated in south and southeastern Brazil. Most ACCs cause hypersecretion of steroids including glucocorticoids and androgens. ACC patients have a very poor prognosis with a 5-year overall survival (OS) below 30% in most series...
December 10, 2018: Clinics
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