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Disconnection syndromes

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https://www.readbyqxmd.com/read/30319536/coincidence-of-tethered-cord-filum-terminale-lipoma-and-sacral-dural-arteriovenous-fistula-report-of-two-cases-and-a-literature-review
#1
Łukasz Przepiórka, Przemysław Kunert, Paulina Juszyńska, Michał Zawadzki, Bogdan Ciszek, Mariusz Głowacki, Andrzej Marchel
Spinal dural arteriovenous fistula (SDAVF) is the most common vascular malformation of the spine in adults. However, the coincidence of tethered cord syndrome, lipoma, and SDAVF on the sacral level is exceptionally rare. We describe two patients, probably the fifth and sixth ever reported. The first was a 33 year-old female who underwent surgical cord de-tethering. Surprisingly, a sacral SDAVF was discovered intraoperatively, despite negative digital subtraction angiography (DSA). The second patient was a 30 year-old male with similar pathologies...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/30294468/contribution-of-diffusion-perfusion-and-functional-mri-to-the-disconnection-hypothesis-in-subcortical-vascular-cognitive-impairment
#2
Qing Ye, Feng Bai
Vascular cognitive impairment (VCI) describes all forms of cognitive impairment caused by any type of cerebrovascular disease. Early identification of VCI is quite difficult due to the lack of both sensitive and specific biomarkers. Extensive damage to the white matter tracts, which connect the cortical and subcortical regions, has been shown in subcortical VCI (SVCI), the most common subtype of VCI that is caused by small vessel disease. Two specific MRI sequences, including diffusion tensor imaging (DTI) and functional MRI (fMRI), have emerged as useful tools for identifying subtle white matter changes and the intrinsic connectivity between distinct cortical regions...
September 2018: Stroke and Vascular Neurology
https://www.readbyqxmd.com/read/30289363/disconnectomics-stroke-related-disconnection-and-dysfunction-in-distributed-brain-networks
#3
Michele Veldsman, Amy Brodtmann
Modern clinical neuroscience was built on observations of how localized damage caused specific functional, cognitive and behavioral deficits. Stroke neurology was a cornerstone of understanding this functional specialization in the brain. But most lesion-symptom mapping provides little prognostic value above clinical observations. Stroke topography remains a poor indicator of long-term outcome, and with stroke a major risk factor for dementia, there is strong incentive to find markers of predictive value. There is now growing recognition that the damage caused by stroke does not occur in isolation but is embedded within a complex, highly interconnected, organized and dynamic system: the connectome...
October 5, 2018: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/30192763/exploring-the-knowledge-explanatory-models-of-illness-and-patterns-of-healthcare-seeking-behaviour-of-fang-culture-bound-syndromes-in-equatorial-guinea
#4
Raquel Jimenez Fernandez, Inmaculada Corral Liria, Rocio Rodriguez Vázquez, Susana Cabrera Fernandez, Marta Elena Losa Iglesias, Ricardo Becerro de Bengoa Vallejo
In 1994, the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) included "culture-bound syndromes" in its classification of psychiatric disorders and associated them with disease processes that manifest in behavioural or thought disorders that develop within a given cultural context. This study examines the definitions, explanatory models, signs and symptoms, and healthcare-seeking behaviours common to Fang culture-bound syndromes (i.e., kong, eluma, witchcraft, mibili, mikug, and nsamadalu)...
2018: PloS One
https://www.readbyqxmd.com/read/30181052/left-superior-vena-cava-draining-into-the-left-atrium-clinical-entities-diagnosis-and-surgical-treatment
#5
Juan M Aguilar, Fernando Rodríguez-Serrano, Andrea Ferreiro-Marzal, María Esteban-Molina, Antonio Gabucio, Enrique García, Lorenzo Boni, José M Garrido
Left superior vena cava draining into the left atrium in the absence of coronary sinus is an anomaly that can appear in heterotaxy syndrome and unroofed coronary sinus syndrome. Regardless of the origin of these syndromes, biventricular repair can be done through rerouting by intracardiac procedures or through disconnection-reconnection of the left superior vena cava to the right atrium or right superior vena cava by extracardiac procedures. Different techniques can be used for this purpose, each of which has its own advantages and limitations...
September 1, 2018: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/30147671/diagonistic-apraxia-a-unique-case-of-corpus-callosal-disconnection-syndrome-and-neuromyelitis-optica-spectrum-disorder
#6
Hidenobu Shozawa, Akinori Futamura, Yu Saito, Motoyasu Honma, Mitsuru Kawamura, Michael W Miller, Kenjiro Ono
Diagonistic apraxia is a corpus callosal disconnection syndrome. Callosal lesions in Neuromyelitis optica spectrum disorder (NMOSD) have been reported, but callosal disconnection syndrome are rare. A 48-year-old woman was treated for fever and a cough before hospitalization. Her fever abated immediately, but she had balance problems in walking and standing. She also had slurred speech. On neurological examination, she had diagonistic apraxia. Her left hand moved in an uncoordinated way when she moved her right hand: changing her clothes for example or using a knife and fork...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/30099539/general-principles-for-preoperative-planning-and-microsurgical-treatment-of-pediatric-brain-arteriovenous-malformations-2-dimensional-operative-video
#7
David L Penn, Kyle C Wu, Kayla R Presswood, Coleman P Riordan, R Michael Scott, Edward R Smith
Children with arteriovenous malformations (AVMs) are at cumulative, life-long risk of debilitating and fatal intracranial hemorrhage, especially with syndromes such as hereditary hemorrhagic telangiectasia. Cerebral angiography is the gold standard for diagnosis and allows simultaneous adjunctive embolization limiting radiation and contrast exposure and intraoperative blood loss, important in pediatric patients with low blood volume. Microsurgical resection of low-grade AVMs offers cure with minimal morbidity...
August 7, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29978030/twin-twin-transfusion-syndrome-and-maternal-symptomatology-an-exploratory-analysis-of-patient-experiences-when-reporting-complaints
#8
Lauren Nicholas, Rebecca Fischbein, Lynn Falletta, Kristin Baughman
Objective: The aim of this study was to assess patient experiences when reporting symptoms of twin-twin transfusion syndrome (TTTS) to their health-care providers. Methodology: The study utilized an online, retrospective survey of women, over the age of 18, who were living in the United States at the time of their pregnancy and had completed a TTTS pregnancy. Results: Three hundred sixty-seven cases were included for analysis. Nearly half of the respondents (45...
June 2018: Journal of Patient Experience
https://www.readbyqxmd.com/read/29952142/gastrointestinal-wrong-connection-an-infected-mediastinal-pseudocyst-complicating-disconnected-duct-syndrome
#9
V Zimmer
No abstract text is available yet for this article.
October 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29946799/better-understanding-and-recognition-of-the-disconnects-experiences-and-needs-of-patients-with-irritable-bowel-syndrome-with-constipation-burden-ibs-c-study-results-of-an-online-questionnaire
#10
Eamonn M M Quigley, John Horn, Michele Kissous-Hunt, Robert A Crozier, Lucinda A Harris
INTRODUCTION: The BURDEN IBS-C study was conducted to better understand the experiences, attitudes, and unmet needs of sufferers of irritable bowel syndrome with constipation (IBS-C) in comparison to the perceptions and challenges of healthcare providers (HCPs) who treat IBS-C patients. METHODS: This was an author-developed, online questionnaire using KnowledgePanel® to survey individuals with IBS-C (N = 1311). HCPs participated in a complementary online questionnaire and were recruited separately (N = 331)...
July 2018: Advances in Therapy
https://www.readbyqxmd.com/read/29901639/reversible-splenial-lesion-syndrome-after-blood-transfusion-presents-callosal-disconnection-syndrome-a-case-report
#11
Xinxin Ma, Wen Su, Haibo Chen
RATIONALE: Reversible splenial lesion syndrome (RESLES) is a reversible condition with an excellent prognosis in most patients. The clinical features include altered states of consciousness, delirium, headache, and seizures, but no callosal disconnection syndromes have been described in RESLES. PATIENT CONCERNS: We presented a 57-year-old patient with alien hand syndrome, autotopagnosia, gait disorders, and left ideomotor apraxia after blood transfusion. The brain magnetic resonance imaging (MRI) showed a few regions with high signal intensity in the genu, body, and splenium of the right corpus callosum on diffusion weighted images...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901514/management-of-complications-of-acute-pancreatitis
#12
Christopher J DiMaio
PURPOSE OF REVIEW: Acute pancreatitis can result in a number of localized complications such as pancreatic pseudocysts, walled-off pancreatic necrosis (WON), and disconnected pancreatic duct syndrome (DPDS). The management of these conditions has evolved over the past three decades such that minimally invasive endoscopic drainage and debridement methods are now the favored, first-line approach. This article will review the latest developments and controversies regarding the endoscopic management of these conditions...
September 2018: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/29895069/disconnected-pancreatic-duct-syndrome-wait-why-not-try-one-more-time
#13
Shu-Ling Wang, Sheng-Bing Zhao, Tian Xia, Zhao-Shen Li, Yu Bai
No abstract text is available yet for this article.
July 2018: Endoscopy
https://www.readbyqxmd.com/read/29861197/formal-thought-disorder-is-related-to-aberrations-in-language-related-white-matter-tracts-in-patients-with-schizophrenia
#14
Marialuisa Cavelti, Stephanie Winkelbeiner, Andrea Federspiel, Sebastian Walther, Katharina Stegmayer, Stéphanie Giezendanner, Karin Laimböck, Thomas Dierks, Werner Strik, Helge Horn, Philipp Homan
This study examined the hypothesis that a fronto-temporal disconnection in the language network underpins formal thought disorder (FTD) in schizophrenia. Forty-nine patients with a schizophrenia spectrum disorder (27 with mild FTD, 22 with severe FTD) and 26 healthy controls (HC) were included. Overall psychopathology and FTD were assessed by the Positive and Negative Syndrome Scale and the Thought, Language, and Communication scale, respectively. White matter (WM) microstructure was analysed using Tract-Based Spatial Statistics...
September 30, 2018: Psychiatry research. Neuroimaging
https://www.readbyqxmd.com/read/29779603/diaphragm-pacing
#15
REVIEW
Anthony F DiMarco
Diaphragm pacing (DP) is a useful and cost-effective alternative to mechanical ventilation in patients with ventilator-dependent spinal cord injury and central hypoventilation syndrome. Patients with SCI should be carefully screened to assess the integrity of their phrenic nerves. In eligible patients, DP improves mobility, speech, olfaction, and quality of life. The stigma of being attached to a mechanical device and risk of ventilator disconnection are eliminated. There is also some evidence that DP results in a reduction in the rate of respiratory tract infections...
June 2018: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29754115/delusional-misidentifications-in-a-procrustean-bed
#16
EDITORIAL
G N Christodoulou, M Margariti, N Christodoulou
The Delusional Misidentification Syndromes (DMSs) are characterized by defective integration of the normally The Delusional Misidentification Syndromes (DMSs) are characterized by defective integration of the normally fused functions of perception and recognition. The classical sub-types are: the syndromes of Capgras, Fregoli,Intermetamorphosis (mentioned in 3) and Subjective doubles. These syndromes occur in a clear sensorium and shouldbe differentiated from the banal transient misidentifications occurring in confusional states and in mania and from thenon-delusional misidentifications (e...
January 2018: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/29699897/development-of-regional-extracorporeal-life-support-system-the-importance-of-innovative-simulation-training
#17
Mateusz Puślecki, Marcin Ligowski, Marek Dąbrowski, Sebastian Stefaniak, Małgorzata Ładzińska, Aleksander Pawlak, Marcin Zieliński, Łukasz Szarpak, Bartłomiej Perek, Marek Jemielity
BACKGROUND: Despite advances in mechanical ventilation, severe acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality rates ranging from 30% to 60%. Extracorporeal Membrane Oxygenation (ECMO) can be used as a "bridge to recovery". ECMO is a complex network that provides oxygenation and ventilation and allows the lungs to rest and recover from respiratory failure, while minimizing iatrogenic ventilator-induced lung injury. In the critical care settings, ECMO is shown to improve survival rates and outcomes in patients with severe ARDS...
April 18, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29685330/relation-of-intrathecal-oligoclonal-band-production-to-inflammatory-mediator-and-immunotherapy-response-in-208-children-with-oms
#18
Michael R Pranzatelli, Nathan R McGee, Elizabeth D Tate
In 208 children with opsoclonus-myoclonus syndrome (OMS), CSF IgG oligoclonal bands (OCB) and 22 immunomarkers in CSF and 21 in serum/blood were measured. In 36 untreated OMS, 58% were OCB(+), whereas 55% of treated OMS were OCB(-). OCB positivity or negativity did not alter concentrations or frequencies of immunomarkers. The phenotypes of OCB(+) and OCB(-) patients were not distinctive. CSF B cells were expanded in untreated OMS regardless of OCB positivity. These data reveal a much higher frequency of OCB positivity in untreated OMS than previously realized and a disconnect between intrathecal OCB and inflammatory mediator production...
August 15, 2018: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/29660042/pediatric-irritable-bowel-syndrome-perspectives-on-pain-and-adolescent-social-functioning
#19
Elizabeth Donovan, Sarah R Martin, Kirsten Lung, Subhadra Evans, Laura C Seidman, Tara M Cousineau, Elizabeth Cook, Lonnie K Zeltzer
Objective: The goal of the study was to describe the experiences of adolescents with irritable bowel syndrome (IBS) from the perspective of adolescents, their parents, and health care providers who treat adolescents who have IBS. Design: The study consisted of semistructured interviews. Setting: Participants were recruited from multidisciplinary pain clinics. Subjects: Thirty-six people participated in the study: 12 adolescents, 12 parents, and 12 health care providers...
April 5, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29627004/brain-connectivity-and-cognitive-processing-speed-in-multiple-sclerosis-a-systematic-review
#20
REVIEW
Riccardo Manca, Basil Sharrack, David Paling, Iain D Wilkinson, Annalena Venneri
BACKGROUND: Processing speed (PS) decline is the most commonly observed cognitive deficit in people with multiple sclerosis (MS) resulting in a significant impact on quality of life. Despite its importance, knowledge of the underlying neural substrates is lacking. OBJECTIVE: As MS is increasingly recognised as a disconnection syndrome, our aim was to carry out a systematic literature review to clarify the relationship between PS performance and MRI measures of structural and functional brain connectivity in people with MS...
May 15, 2018: Journal of the Neurological Sciences
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