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Disconnection syndromes

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https://www.readbyqxmd.com/read/30099539/general-principles-for-preoperative-planning-and-microsurgical-treatment-of-pediatric-brain-arteriovenous-malformations-2-dimensional-operative-video
#1
David L Penn, Kyle C Wu, Kayla R Presswood, Coleman P Riordan, R Michael Scott, Edward R Smith
Children with arteriovenous malformations (AVMs) are at cumulative, life-long risk of debilitating and fatal intracranial hemorrhage, especially with syndromes such as hereditary hemorrhagic telangiectasia. Cerebral angiography is the gold standard for diagnosis and allows simultaneous adjunctive embolization limiting radiation and contrast exposure and intraoperative blood loss, important in pediatric patients with low blood volume. Microsurgical resection of low-grade AVMs offers cure with minimal morbidity...
August 7, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29978030/twin-twin-transfusion-syndrome-and-maternal-symptomatology-an-exploratory-analysis-of-patient-experiences-when-reporting-complaints
#2
Lauren Nicholas, Rebecca Fischbein, Lynn Falletta, Kristin Baughman
Objective: The aim of this study was to assess patient experiences when reporting symptoms of twin-twin transfusion syndrome (TTTS) to their health-care providers. Methodology: The study utilized an online, retrospective survey of women, over the age of 18, who were living in the United States at the time of their pregnancy and had completed a TTTS pregnancy. Results: Three hundred sixty-seven cases were included for analysis. Nearly half of the respondents (45...
June 2018: Journal of Patient Experience
https://www.readbyqxmd.com/read/29952142/gastrointestinal-wrong-connection-an-infected-mediastinal-pseudocyst-complicating-disconnected-duct-syndrome
#3
V Zimmer
No abstract text is available yet for this article.
June 27, 2018: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29946799/better-understanding-and-recognition-of-the-disconnects-experiences-and-needs-of-patients-with-irritable-bowel-syndrome-with-constipation-burden-ibs-c-study-results-of-an-online-questionnaire
#4
Eamonn M M Quigley, John Horn, Michele Kissous-Hunt, Robert A Crozier, Lucinda A Harris
INTRODUCTION: The BURDEN IBS-C study was conducted to better understand the experiences, attitudes, and unmet needs of sufferers of irritable bowel syndrome with constipation (IBS-C) in comparison to the perceptions and challenges of healthcare providers (HCPs) who treat IBS-C patients. METHODS: This was an author-developed, online questionnaire using KnowledgePanel® to survey individuals with IBS-C (N = 1311). HCPs participated in a complementary online questionnaire and were recruited separately (N = 331)...
July 2018: Advances in Therapy
https://www.readbyqxmd.com/read/29901639/reversible-splenial-lesion-syndrome-after-blood-transfusion-presents-callosal-disconnection-syndrome-a-case-report
#5
Xinxin Ma, Wen Su, Haibo Chen
RATIONALE: Reversible splenial lesion syndrome (RESLES) is a reversible condition with an excellent prognosis in most patients. The clinical features include altered states of consciousness, delirium, headache, and seizures, but no callosal disconnection syndromes have been described in RESLES. PATIENT CONCERNS: We presented a 57-year-old patient with alien hand syndrome, autotopagnosia, gait disorders, and left ideomotor apraxia after blood transfusion. The brain magnetic resonance imaging (MRI) showed a few regions with high signal intensity in the genu, body, and splenium of the right corpus callosum on diffusion weighted images...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901514/management-of-complications-of-acute-pancreatitis
#6
Christopher J DiMaio
PURPOSE OF REVIEW: Acute pancreatitis can result in a number of localized complications such as pancreatic pseudocysts, walled-off pancreatic necrosis (WON), and disconnected pancreatic duct syndrome (DPDS). The management of these conditions has evolved over the past three decades such that minimally invasive endoscopic drainage and debridement methods are now the favored, first-line approach. This article will review the latest developments and controversies regarding the endoscopic management of these conditions...
June 12, 2018: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/29895069/disconnected-pancreatic-duct-syndrome-wait-why-not-try-one-more-time
#7
Shu-Ling Wang, Sheng-Bing Zhao, Tian Xia, Zhao-Shen Li, Yu Bai
No abstract text is available yet for this article.
July 2018: Endoscopy
https://www.readbyqxmd.com/read/29861197/formal-thought-disorder-is-related-to-aberrations-in-language-related-white-matter-tracts-in-patients-with-schizophrenia
#8
Marialuisa Cavelti, Stephanie Winkelbeiner, Andrea Federspiel, Sebastian Walther, Katharina Stegmayer, Stéphanie Giezendanner, Karin Laimböck, Thomas Dierks, Werner Strik, Helge Horn, Philipp Homan
This study examined the hypothesis that a fronto-temporal disconnection in the language network underpins formal thought disorder (FTD) in schizophrenia. Forty-nine patients with a schizophrenia spectrum disorder (27 with mild FTD, 22 with severe FTD) and 26 healthy controls (HC) were included. Overall psychopathology and FTD were assessed by the Positive and Negative Syndrome Scale and the Thought, Language, and Communication scale, respectively. White matter (WM) microstructure was analysed using Tract-Based Spatial Statistics...
May 23, 2018: Psychiatry research. Neuroimaging
https://www.readbyqxmd.com/read/29779603/diaphragm-pacing
#9
REVIEW
Anthony F DiMarco
Diaphragm pacing (DP) is a useful and cost-effective alternative to mechanical ventilation in patients with ventilator-dependent spinal cord injury and central hypoventilation syndrome. Patients with SCI should be carefully screened to assess the integrity of their phrenic nerves. In eligible patients, DP improves mobility, speech, olfaction, and quality of life. The stigma of being attached to a mechanical device and risk of ventilator disconnection are eliminated. There is also some evidence that DP results in a reduction in the rate of respiratory tract infections...
June 2018: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29754115/delusional-misidentifications-in-a-procrustean-bed
#10
EDITORIAL
G N Christodoulou, M Margariti, N Christodoulou
The Delusional Misidentification Syndromes (DMSs) are characterized by defective integration of the normally The Delusional Misidentification Syndromes (DMSs) are characterized by defective integration of the normally fused functions of perception and recognition. The classical sub-types are: the syndromes of Capgras, Fregoli,Intermetamorphosis (mentioned in 3) and Subjective doubles. These syndromes occur in a clear sensorium and shouldbe differentiated from the banal transient misidentifications occurring in confusional states and in mania and from thenon-delusional misidentifications (e...
January 2018: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/29699897/development-of-regional-extracorporeal-life-support-system-the-importance-of-innovative-simulation-training
#11
Mateusz Puślecki, Marcin Ligowski, Marek Dąbrowski, Sebastian Stefaniak, Małgorzata Ładzińska, Aleksander Pawlak, Marcin Zieliński, Łukasz Szarpak, Bartłomiej Perek, Marek Jemielity
BACKGROUND: Despite advances in mechanical ventilation, severe acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality rates ranging from 30% to 60%. Extracorporeal Membrane Oxygenation (ECMO) can be used as a "bridge to recovery". ECMO is a complex network that provides oxygenation and ventilation and allows the lungs to rest and recover from respiratory failure, while minimizing iatrogenic ventilator-induced lung injury. In the critical care settings, ECMO is shown to improve survival rates and outcomes in patients with severe ARDS...
April 18, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29685330/relation-of-intrathecal-oligoclonal-band-production-to-inflammatory-mediator-and-immunotherapy-response-in-208-children-with-oms
#12
Michael R Pranzatelli, Nathan R McGee, Elizabeth D Tate
In 208 children with opsoclonus-myoclonus syndrome (OMS), CSF IgG oligoclonal bands (OCB) and 22 immunomarkers in CSF and 21 in serum/blood were measured. In 36 untreated OMS, 58% were OCB(+), whereas 55% of treated OMS were OCB(-). OCB positivity or negativity did not alter concentrations or frequencies of immunomarkers. The phenotypes of OCB(+) and OCB(-) patients were not distinctive. CSF B cells were expanded in untreated OMS regardless of OCB positivity. These data reveal a much higher frequency of OCB positivity in untreated OMS than previously realized and a disconnect between intrathecal OCB and inflammatory mediator production...
August 15, 2018: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/29660042/pediatric-irritable-bowel-syndrome-perspectives-on-pain-and-adolescent-social-functioning
#13
Elizabeth Donovan, Sarah R Martin, Kirsten Lung, Subhadra Evans, Laura C Seidman, Tara M Cousineau, Elizabeth Cook, Lonnie K Zeltzer
Objective: The goal of the study was to describe the experiences of adolescents with irritable bowel syndrome (IBS) from the perspective of adolescents, their parents, and health care providers who treat adolescents who have IBS. Design: The study consisted of semistructured interviews. Setting: Participants were recruited from multidisciplinary pain clinics. Subjects: Thirty-six people participated in the study: 12 adolescents, 12 parents, and 12 health care providers...
April 5, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29627004/brain-connectivity-and-cognitive-processing-speed-in-multiple-sclerosis-a-systematic-review
#14
REVIEW
Riccardo Manca, Basil Sharrack, David Paling, Iain D Wilkinson, Annalena Venneri
BACKGROUND: Processing speed (PS) decline is the most commonly observed cognitive deficit in people with multiple sclerosis (MS) resulting in a significant impact on quality of life. Despite its importance, knowledge of the underlying neural substrates is lacking. OBJECTIVE: As MS is increasingly recognised as a disconnection syndrome, our aim was to carry out a systematic literature review to clarify the relationship between PS performance and MRI measures of structural and functional brain connectivity in people with MS...
May 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29607759/-it-s-like-being-a-slave-to-your-own-body-in-a-way-a-qualitative-study-of-adolescents-with-chronic-fatigue-syndrome
#15
Berit Widerøe Njølstad, Anne Marit Mengshoel, Unni Sveen
BACKGROUND: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a relatively common disabling illness in adolescents that may limit participation in daily life. AIM: This study explored interactions between the illness experiences of adolescents with CFS/ME, their occupational lives and expectations for the future. METHODS: Seven adolescents with CFS/ME were interviewed. The interviews were analyzed using thematic analysis. RESULTS: Three themes were developed...
April 1, 2018: Scandinavian Journal of Occupational Therapy
https://www.readbyqxmd.com/read/29606344/agraphia-with-reversible-splenial-corpus-callosum-lesion-caused-by-hypoglycemia
#16
Yukari Miyakawa, Tatsuo Fuchigami, Masako Aoki, Yusuke Mine, Junichi Suzuki, Tatsuhiko Urakami, Shori Takahashi
BACKGROUND: Neurological manifestations caused by hypoglycemia range from reversible focal deficits and transient encephalopathy to irreversible coma or death. Recently, high signal intensity lesions in the splenium of the corpus callosum on diffusion-weighted magnetic resonance imaging were reported in adults experiencing hypoglycemia. However, patients presenting with agraphia are rare. SUBJECT AND METHODS: We examined a 17-year-old left-handed female patient with type 1 diabetes who exhibited transient left agraphia with a reversible splenium lesion of the corpus callosum on diffusion-weighted imaging caused by hypoglycemia, which was improved with blood glucose management alone...
August 2018: Brain & Development
https://www.readbyqxmd.com/read/29573816/diabetes-mellitus-prevalence-in-patients-with-takotsubo-syndrome-the-case-of-the-brain-heart-disconnect
#17
John E Madias
BACKGROUND: Hyperactive autonomic nervous system (ANS) is among the postulated pathophysiologic mechanisms of takotsubo syndrome (TTS). Diabetes mellitus (DM) with its associated ANS peripheral neuropathy could exert a "protective" influence for the emergence of TTS. METHODS: A patient-based meta-analysis of the data obtained from all patients presented individually was carried out, focusing on age, gender, and history of hypertension (HTN) and DM. RESULTS: The prevalences of HTN and DM for all 2,342 patients, aged 61...
May 2018: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/29572915/developmental-conduction-aphasia-after-neonatal-stroke
#18
Gemma B Northam, Sophie Adler, Kathrin C J Eschmann, Wui K Chong, Frances M Cowan, Torsten Baldeweg
OBJECTIVE: Impairment of speech repetition following injury to the dorsal language stream is a feature of conduction aphasia, a well-described "disconnection syndrome" in adults. The impact of similar lesions sustained in infancy has not been established. METHODS: We compared language outcomes in term-born individuals with confirmed neonatal stroke (n = 30, age = 7-18 years, left-sided lesions in 21 cases) to matched controls (n = 40). Injury to the dorsal and/or ventral language streams was assessed using T1 - and T2 -weighted magnetic resonance imaging (MRI) and diffusion tractography...
April 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29541539/the-crossed-frontal-aslant-tract-a-possible-pathway-involved-in-the-recovery-of-supplementary-motor-area-syndrome
#19
Cordell M Baker, Joshua D Burks, Robert G Briggs, Adam D Smitherman, Chad A Glenn, Andrew K Conner, Dee H Wu, Michael E Sughrue
Introduction: Supplementary motor area (SMA) syndrome is a constellation of temporary symptoms that may occur following tumors of the frontal lobe. Affected patients develop akinesia and mutism but often recover within weeks to months. With our own case examples and with correlations to fiber tracking validated by gross anatomical dissection as ground truth, we describe a white matter pathway through which recovery may occur. Methods: Diffusion spectrum imaging from the Human Connectome Project was used for tractography analysis...
March 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29519471/gerstmann-syndrome-historic-and-current-perspectives
#20
Elena Rusconi
This chapter offers a perspective on the origin, operational definition, historic vicissitudes, and current status of Gerstmann syndrome. The main issues and controversy accompanying Gerstmann syndrome throughout the years are reviewed. The clinical picture of Gerstmann syndrome as it emerges from a series of modern-day pure cases is described. In current clinical practice, a diagnosis of Gerstmann syndrome indicates the concomitant presence of four acquired symptoms: finger agnosia, acalculia, left-right disorientation, and agraphia...
2018: Handbook of Clinical Neurology
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