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Ming Yan, Qiang Hao, Xuling Shen, Heping Zeng
Polarization evolution locking (PEL) of a stretched-pulse fiber laser is experimentally investigated with a simple pulse selection method based on a fast electrooptic modulator, capable of revealing the temporal and spectrum evolution of the PEL pulses. Moreover, the wavelength dependence of PEL is observed by spectrally filtering the pulses and is further investigated for individual fiber laser comb lines through beat note measurements with narrow-linewidth cw lasers.
June 25, 2018: Optics Express
Niketh Nair, Erik Bochove, Yehuda Braiman
In this paper we study the conditions for achieving almost perfect phase locking in large arrays of semiconductor diodes. We show that decayed non-local coupling of diode lasers can provide the necessary conditions for robust phase synchronization of an entire diode laser array. Perfect global coupling is known to allow for robust synchronization, however it is often physically impossible or impractical to achieve. We show that when diodes are coupled via the decayed non-local coupling layout, the dominant transverse mode of the laser array has a uniform phase across the lasers and can be stable...
August 6, 2018: Optics Express
Xiaojun Jin, Yi Lin, Ying Lu, Huilian Ma, Zhonghe Jin
Optical gyros are attractive angular rotation sensors based on the Sagnac effect. The phase modulation technique is adopted to detect the weak resonant frequency shift induced by the Sagnac effect, which determines the detection sensitivity of the gyros. The Pound-Drever-Hall (PDH) modulation is a mature laser frequency stabilization technique that is widely recognized. A resonant optic gyro equipped with a short and high-finesse fiber ring resonator employing the high-frequency PDH modulation technique is proposed and demonstrated...
July 10, 2018: Applied Optics
L Muzika, M Švantner, M Kučera
Inspection of solar cells is an important part of their production process because even small defects can cause a significant drop of a whole photovoltaic module performance. LED illuminated lock-in (LEDILIT) and flash-pulse thermographic techniques (FPT) were compared in this study. Lock-in methods are more commonly used for solar cell inspection. The aim of the study was to discover if the FPT is the appropriate method for inspection of defects of multicrystalline solar cells. Experimental setup, inspection results, and advantages/disadvantages of both methods are presented...
June 20, 2018: Applied Optics
Hao Shi, Jie Ma, Xiaofeng Li, Jie Liu, Shougang Zhang
A concise laser system for optically pumped cesium beam clocks is presented. The laser's frequency is locked by a fluorescence signal, produced by the interaction between a cesium atomic beam and laser. A cesium oven with a longer atom source collimator, formed by an array of channels, was used to reduce the divergence angle of the cesium atomic beam. The size of the cesium source collimator is 4  mm×0.6  mm, and the cesium expenditure rate is 2.4×10-1   g per year. A dense cesium atomic flux was used to interact with the laser to generate a fluorescence signal when the oven heating temperature is not too high...
August 1, 2018: Applied Optics
Max Waldherr, Nils Lundt, Martin Klaas, Simon Betzold, Matthias Wurdack, Vasilij Baumann, Eliezer Estrecho, Anton Nalitov, Evgenia Cherotchenko, Hui Cai, Elena A Ostrovskaya, Alexey V Kavokin, Sefaattin Tongay, Sebastian Klembt, Sven Höfling, Christian Schneider
Bosonic condensation belongs to the most intriguing phenomena in physics, and was mostly reserved for experiments with ultra-cold quantum gases. More recently, it became accessible in exciton-based solid-state systems at elevated temperatures. Here, we demonstrate bosonic condensation driven by excitons hosted in an atomically thin layer of MoSe2 , strongly coupled to light in a solid-state resonator. The structure is operated in the regime of collective strong coupling between a Tamm-plasmon resonance, GaAs quantum well excitons, and two-dimensional excitons confined in the monolayer crystal...
August 16, 2018: Nature Communications
Lorenzo Luigi Columbo, Paolo Bardella, Mariangela Gioannini
We studied theoretically coherent phenomena in the multimode dynamics of single section semiconductor ring lasers with quantum dots (QDs) active region. In the unidirectional ring configuration our simulations show the occurrence of self-mode-locking in the system leading to ultra-short pulses (sub-picoseconds) with a terahertz repetition rate. As confirmed by the linear stability analysis (LSA) of the traveling wave (TW) solutions this phenomenon is triggered by an analogous of the Risken-Nummedal-Graham-Haken (RNGH) instability affecting the multimode dynamics of two-level lasers...
July 23, 2018: Optics Express
Zhixiu Li, Xiaocong Sun, Yajun Wang, Yaohui Zheng, Kunchi Peng
We present an analysis on how the optical parametric oscillator (OPO) detuning and the relative phase drift deteriorate the stability of the squeezed states, including the output power and the squeezed degree, and investigate the influence of RAM on the cavity detuning and the relative phase drift under different cases. Subsequently, the RAM is experimentally measured. In term of the measurement results, we perform a comparative study about RAM's influence on the cavity and phase locking in two cases. As a result, with the error signal extracted from the transmission of the OPO, the output power stability of the squeezed light is greatly improved...
July 23, 2018: Optics Express
Alexander Heilinger, Rupert Ortner, Vincenzo La Bella, Zulay R Lugo, Camille Chatelle, Steven Laureys, Rossella Spataro, Christoph Guger
Patients with locked-in syndrome (LIS) are typically unable to move or communicate and can be misdiagnosed as patients with disorders of consciousness (DOC). Behavioral assessment scales are limited in their ability to detect signs of consciousness in this population. Recent research has shown that brain-computer interface (BCI) technology could supplement behavioral scales and allows to establish communication with these severely disabled patients. In this study, we compared the vibro-tactile P300 based BCI performance in two groups of patients with LIS of different etiologies: stroke ( n = 6) and amyotrophic lateral sclerosis (ALS) ( n = 9)...
2018: Frontiers in Neuroscience
Paul Vetschera, Kanuj Mishra, Juan-Pablo Fuenzalida Werner, Andriy Chmyrov, Vasilis Ntziachristos, Andre C Stiel
Reversibly switchable fluorescent proteins (rsFPs) have had a revolutionizing effect on life science imaging due to their contribution to subdiffraction-resolution optical microscopy (nanoscopy). Initial studies showed that their use as labels could also be highly beneficial for emerging Photo- or Optoacoustic imaging. It could be shown that their use in Optoacoustics i) strongly improves the imaging CNR due to modulation and locked-in detection, ii) facilitates fluence calibration affording precise measurements of physiological parameters and finally iii) could boost spatial resolution following similar concepts as used for nanoscopy...
August 6, 2018: Analytical Chemistry
Yue Lai, Xiao Kuang, Ping Zhu, Miaoming Huang, Xia Dong, Dujin Wang
Robust self-healing thermoplastic elastomers are expected to have repeated healing capability, remarkable mechanical properties, transparency, and superior toughness. The phase-locked design in this work provides excellent tensile mechanical properties and efficient healability at a moderate temperature due to the dynamic disulfide bonds embedded in the hard segments and mainly being locked in the viscoelastic hard microphase region. The self-healing elastomers exhibit a maximum tensile stress of 25 MPa and a fracture strain of over 1600%, which are quite prominent compared to previous reports...
August 2, 2018: Advanced Materials
Junhua Chen, Shu Chen, Fengling Li
A series of advanced logic circuits have been successfully constructed to perform multiple arithmetic functions using a lateral flow strip biosensor as the sensing platform, including half adder, half subtractor, multiplexer, demultiplexer, and keypad lock. In each circuit computing, the computing elements are the DNA probes, which can implement the DNA assembly process to generate the output single-stranded nucleic acid. The strip biosensor is used as the sensing platform to distinguish the output of the logic gates...
August 17, 2018: Analytical Chemistry
Simon J Cassidy, Fabio Orlandi, Pascal Manuel, Joke Hadermann, Alex Scrimshire, Paul A Bingham, Simon J Clarke
Sr2 Fe3 Se2 O3 is a localized-moment iron oxide selenide in which two unusual coordinations for Fe2+ ions form two sublattices in a 2:1 ratio. In the paramagnetic region at room temperature, the compound adopts the crystal structure first reported for Sr2 Co3 S2 O3 , crystallizing in space group Pbam with a = 7.8121 Å, b = 10.2375 Å, c = 3.9939 Å, and Z = 2. The sublattice occupied by two-thirds of the iron ions (Fe2 site) is formed by a network of distorted mer-[FeSe3 O3 ] octahedra linked via shared Se2 edges and O vertices forming layers, which connect to other layers by shared Se vertices...
July 31, 2018: Inorganic Chemistry
Daigo Nakazawa, Jyaysi Desai, Stefanie Steiger, Susanne Müller, Satish Kumar Devarapu, Shrikant R Mulay, Takamasa Iwakura, Hans-Joachim Anders
Venous thromboembolic (VTE) disease, often manifesting as deep vein thrombosis or pulmonary embolism, involves clot formation consisting of blood cells and platelets locked in plasma protein and chromatin networks. The latter derives from neutrophil extracellular traps released by dying neutrophils; however, the molecular mechanisms of neutrophil death in VTE remains unknown. We speculated that mixed lineage kinase-like (MLKL)-driven neutrophil necroptosis contributes to VTE. Indeed, human inferior venous cava thrombus material stained positive for phosphorylated MLKL, the activated version of MLKL that executes necroptotic cell death...
2018: Cell Death Discovery
Asieh Ahani, Mohammad Moghadamfalahi, Deniz Erdogmus
Augmentative and alternative communication (AAC) is typically used by people with severe speech and physical disabilities (SSPI) and is one of the main application areas for brain computer interface (BCI) technology. The target population includes people with cerebral palsy (CP), amyotrophic lateral sclerosis (ALS) and locked-in-syndrome (LIS). Word-based AAC systems are mainly faster than letter-based counterparts and are usually supplemented by icons to aid the users. Those iconbased AAC systems that use binary signaling methods such as single click can convert into a single input BCI systems such as ERP detection...
July 25, 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
Peng Zhang, Jun-Hao Lei, Xin-Jun Su, Xing-Huan Wang
BACKGROUND: Current evidence regarding the efficacy of ethanol locks in preventing catheter-related bloodstream infection (CRBI) is inconclusive. METHODS: Electronic databases, including PubMed, Web of Science, Embase, and the Cochrane Library (until April 2018),were systematically searched for relevant studies. Two reviewers independently screened the retrieved records and identified RCTs that met the inclusion criteria. Relevant data were extracted for pooled analyses using Review Manager 5...
July 24, 2018: BMC Anesthesiology
Josh V Vermaas, Susan B Rempe, Emad Tajkhorshid
EmrE is a small, homodimeric membrane transporter that exploits the established electrochemical proton gradient across the Escherichia coli inner membrane to export toxic polyaromatic cations, prototypical of the wider small-multidrug resistance transporter family. While prior studies have established many fundamental aspects of the specificity and rate of substrate transport in EmrE, low resolution of available structures has hampered identification of the transport coupling mechanism. Here we present a complete, refined atomic structure of EmrE optimized against available cryo-electron microscopy (cryo-EM) data to delineate the critical interactions by which EmrE regulates its conformation during the transport process...
August 7, 2018: Proceedings of the National Academy of Sciences of the United States of America
Ingo Hertrich, Susanne Dietrich, Hermann Ackermann
Cross-correlation of magnetoencephalography (MEG) with time courses derived from the speech signal has shown differences in phase-locking between blind subjects able to comprehend accelerated speech and sighted controls. The present training study contributes to disentangle the effects of blindness and training. Both subject groups (baseline: n = 16 blind, 13 sighted; trained: 10 blind, 3 sighted) were able to enhance speech comprehension up to ca. 18 syllables per second. MEG responses phase-locked to syllable onsets were captured in five pre-defined source locations comprising left and right auditory cortex (A1), right visual cortex (V1), left inferior frontal gyrus (IFG) and left pre-supplementary motor area...
July 16, 2018: Brain and Language
Igor Radanović, Robert Likić
Blockchain technology is a decentralized database that stores a registry of assets and transactions across a peer-to-peer computer network, which is secured through cryptography, and over time, its history gets locked in blocks of data that are cryptographically linked together and secured. So far, there have been use cases of this technology for cryptocurrencies, digital contracts, financial and public records, and property ownership. It is expected that future uses will expand into medicine, science, education, intellectual property, and supply chain management...
July 18, 2018: Applied Health Economics and Health Policy
David Jon Wasilko, Qingqiu Huang, Yuxin Mao
The causative agent of Legionnaires' disease, Legionella pneumophila , delivers more than 330 virulent effectors to its host to establish an intracellular membrane-bound organelle called the Legionella containing vacuole. Among the army of Legionella effectors, SidC and its paralog SdcA have been identified as novel bacterial ubiquitin (Ub) E3 ligases. To gain insight into the molecular mechanism of SidC/SdcA as Ub ligases, we determined the crystal structures of a binary complex of the N-terminal catalytic SNL domain of SdcA with its cognate E2 UbcH5C and a ternary complex consisting of the SNL domain of SidC with the Ub-linked E2 UbcH7...
July 17, 2018: ELife
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