keyword
MENU ▼
Read by QxMD icon Read
search

Ldr

keyword
https://www.readbyqxmd.com/read/28199317/colorimetric-tests-for-diagnosis-of-filarial-infection-and-vector-surveillance-using-non-instrumented-nucleic-acid-loop-mediated-isothermal-amplification-nina-lamp
#1
Catherine B Poole, Zhiru Li, Andy Alhassan, Dylan Guelig, Steven Diesburg, Nathan A Tanner, Yinhua Zhang, Thomas C Evans, Paul LaBarre, Samuel Wanji, Robert A Burton, Clotilde K S Carlow
Accurate detection of filarial parasites in humans is essential for the implementation and evaluation of mass drug administration programs to control onchocerciasis and lymphatic filariasis. Determining the infection levels in vector populations is also important for assessing transmission, deciding when drug treatments may be terminated and for monitoring recrudescence. Immunological methods to detect infection in humans are available, however, cross-reactivity issues have been reported. Nucleic acid-based molecular assays offer high levels of specificity and sensitivity, and can be used to detect infection in both humans and vectors...
2017: PloS One
https://www.readbyqxmd.com/read/28188489/effects-of-low-dose-radiation-on-adaptive-response-in-colon-cancer-stem-cells
#2
X Zhao, J-W Cui, J-H Hu, S-J Gao, X-L Liu
PURPOSE: Biological effects of low-dose radiation (LDR) are distinguishable from those of high-dose radiation. Adaptive response is an important biological effect following low-dose radiation. Cancer stem cells (CSCs) have self-renewal and multidirectional differentiation potency which results in relapse and metastasis of cancer. In this study, we aimed to examine whether adaptive response could be induced in CSCs by LDR. METHODS: Parental cells of three colon cancer cell lines (HRT18, HT29, and HCT116) and CSCs of these three cell lines were irradiated with LDR (i...
February 10, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28169196/patterns-of-care-of-cervical-cancer-in-the-elderly-a-qualitative-literature-review
#3
Venkatesulu Bhanu Prasad, Supriya Mallick, G K Rath
INTRODUCTION: Cancer of the uterine cervix is the fourth most common cancer worldwide among women. However, there is limited data about elderly cervical cancer patients and gross underrepresentation of elderly patients in clinical trials. Hence, the optimal therapy of such patients is not well formulated. METHODOLOGY: We conducted this systematic review of evidence to assess patterns of care in elderly patients with cervical cancer. RESULTS: A total of 17,338 publications are reported in PubMed until July, 2016 pertaining to cervical cancer...
February 3, 2017: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28153248/confocal-laser-induced-fluorescence-detector-for-narrow-capillary-system-with-yoctomole-limit-of-detection
#4
Mitchell T Weaver, Kyle B Lynch, Zaifang Zhu, Huang Chen, Joann J Lu, Qiaosheng Pu, Shaorong Liu
Laser-induced fluorescence (LIF) detectors for low-micrometer and sub-micrometer capillary on-column detection are not commercially available. In this paper, we describe in details how to construct a confocal LIF detector to address this issue. We characterize the detector by determining its limit of detection (LOD), linear dynamic range (LDR) and background signal drift; a very low LOD (~70 fluorescein molecules or 12 yoctomole fluorescein), a wide LDR (greater than 3 orders of magnitude) and a small background signal drift (~1...
April 1, 2017: Talanta
https://www.readbyqxmd.com/read/28150400/tissue-sodium-accumulation-and-peripheral-insulin-sensitivity-in-maintenance-hemodialysis-patients
#5
Serpil Muge Deger, Ping Wang, Rachel Fissell, Charles D Ellis, Cindy Booker, Feng Sha, Jennifer L Morse, Thomas G Stewart, John C Gore, Edward D Siew, Jens Titze, Talat Alp Ikizler
BACKGROUND: Recent data suggest that sodium (Na(+) ) is stored in the muscle and skin without commensurate water retention in maintenance hemodialysis (MHD) patients. In this study, we hypothesized that excessive Na(+) accumulation would be associated with abnormalities in peripheral insulin action. METHODS: Eleven MHD patients and eight controls underwent hyperinsulinemic-euglycemic-euaminoacidemic clamp studies to measure glucose (GDR) and leucine disposal rates (LDR), as well as lower left leg (23) Na magnetic resonance imaging to measure Na(+) concentration in the muscle and skin tissue...
February 1, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28144702/endovascular-thrombectomy-in-acute-ischemic-stroke-outcome-in-referred-versus-directly-admitted-patients
#6
Philipp Bücke, Marta Aguilar Pérez, Elisabeth Schmid, Christian H Nolte, Hansjörg Bäzner, Hans Henkes
PURPOSE: Endovascular mechanical thrombectomy (mTE) in acute ischemic stroke due to large cerebral artery occlusion is effective and safe. The procedure is currently offered by specialized hospitals. Physicians from smaller hospitals need to refer patients to stroke centers. Secondary referrals involve delays for transportation. Little is known about effects of distant referrals on outcome and complications as compared to direct admittance. METHODS: To evaluate the effects of referral patterns on outcome and safety, we analyzed 941 patients with anterior circulation stroke receiving mTE between January 2010 and December 2015...
January 31, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28140369/modeling-the-impact-of-prostate-edema-on-ldr-brachytherapy-a-monte-carlo-dosimetry-study-based-on-a-3d-biphasic-finite-element-biomechanical-model
#7
K A Mountris, J Bert, J Noailly, A Rodriguez Aguilera, A Valeri, O Pradier, U Schick, E Promayon, M A Gonzalez Ballester, J Troccaz, D Visvikis
Prostate volume changes due to edema occurrence during transperineal permanent brachytherapy should be taken under consideration to ensure optimal dose delivery. Available edema models, based on prostate volume observations, face several limitations. Therefore, patient-specific models need to be developed to accurately account for the impact of edema. In this study we present a biomechanical model developed to reproduce edema resolution patterns documented in the literature. Using the biphasic mixture theory and finite element analysis, the proposed model takes into consideration the mechanical properties of the pubic area tissues in the evolution of prostate edema...
January 31, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28139423/outpatient-template-guided-permanent-interstitial-brachytherapy-using-131-cs-in-gynecologic-malignancies-initial-report
#8
Jonathan Feddock, Prakash Aryal, Cole Steber, Jason Edwards, Dennis Cheek, Marcus Randall
PURPOSE: Optimal curative intent brachytherapy for certain gynecologic cancers requires interstitial brachytherapy, often using template-guided techniques such as a Syed-Neblett implant. Whether high or low dose rate (LDR), these procedures pose significant risks to patients, partly attributable to the prolonged period of bed rest. Published results of free-handed permanent interstitial brachytherapy (PIB) with (131)Cs demonstrate it to be an effective modality for the management of small volume gynecologic cancers...
January 27, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28139420/transition-from-ldr-to-hdr-brachytherapy-for-cervical-cancer-evaluation-of-tumor-control-survival-and-toxicity
#9
K D Romano, K J Pugh, D M Trifiletti, B Libby, T N Showalter
PURPOSE: In 2012, our institution transitioned from low-dose-rate (LDR) brachytherapy to high dose-rate (HDR) brachytherapy. We report clinical outcomes after brachytherapy for cervical cancer at our institution over a continuous 10-year period. METHODS AND MATERIALS: From 2004 to 2014, 258 women (184 LDR and 74 HDR) were treated with tandem and ovoid brachytherapy in the multidisciplinary management of International Federation of Gynecology and Obstetrics Stages IA-IVB cervical cancer...
January 27, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28134809/hormetic-response-to-low-dose-radiation-focus-on-the-immune-system-and-its-clinical-implications
#10
REVIEW
Jiuwei Cui, Guozi Yang, Zhenyu Pan, Yuguang Zhao, Xinyue Liang, Wei Li, Lu Cai
The interrelationship between ionizing radiation and the immune system is complex, multifactorial, and dependent on radiation dose/quality and immune cell type. High-dose radiation usually results in immune suppression. On the contrary, low-dose radiation (LDR) modulates a variety of immune responses that have exhibited the properties of immune hormesis. Although the underlying molecular mechanism is not fully understood yet, LDR has been used clinically for the treatment of autoimmune diseases and malignant tumors...
January 27, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28129172/mr360-mixed-reality-rendering-for-360-%C3%A2-panoramic-videos
#11
Taehyun Rhee, Lohit Petikam, Benjamin Allen, Andrew Chalmers
This paper presents a novel immersive system called MR360 that provides interactive mixed reality (MR) experiences using a conventional low dynamic range (LDR) 360 (°) panoramic video (360-video) shown in head mounted displays (HMDs). MR360 seamlessly composites 3D virtual objects into a live 360-video using the input panoramic video as the lighting source to illuminate the virtual objects. Image based lighting (IBL) is perceptually optimized to provide fast and believable results using the LDR 360-video as the lighting source...
January 23, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28121931/copy-number-variations-exploration-of-multiple-genes-in-graves-disease
#12
Rong-Hua Song, Xiao-Qing Shao, Ling Li, Wen Wang, Jin-An Zhang
BACKGROUND: Few previous published papers reported copy number variations of genes could affect the predisposition of Graves' disease (GD). Herein, the aim of this study was to explore the association between copy number variations (CNV) profile and GD. METHODS: The preliminary copy number microarray used to screen copy number variant genes was performed in 6 GD patients. Five CNV candidate genes (CFH, CFHR1, KIAA0125, UGT2B15, and UGT2B17) were then validated in an independent set of samples (50 GD patients and 50 matched healthy ones) by the Accucopy assay method...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28118951/brachyview-combining-ldr-seed-positions-with-transrectal-ultrasound-imaging-in-a-prostate-gel-phantom
#13
S Alnaghy, D L Cutajar, J A Bucci, K Enari, M Safavi-Naeini, M Favoino, M Tartaglia, F Carriero, J Jakubek, S Pospisil, M Lerch, A B Rosenfeld, M Petasecca
PURPOSE: BrachyView is a novel in-body imaging system which aims to provide LDR brachytherapy seeds position reconstruction within the prostate in real-time. The first prototype is presented in this study: the probe consists of a gamma camera featuring three single cone pinhole collimators embedded in a tungsten tube, above three, high resolution pixelated detectors (Timepix). METHODS: The prostate was imaged with a TRUS system using a sagittal crystal with a 2...
January 21, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28113431/inter-layer-prediction-of-color-in-high-dynamic-range-image-scalable-compression
#14
Mikael Le Pendu, Christine Guillemot, Dominique Thoreau
This paper presents a color inter layer prediction (ILP) method for scalable coding of High Dynamic Range (HDR) video content with a Low Dynamic Range (LDR) base layer. Relying on the assumption of hue preservation between the colors of an HDR image and its LDR tone mapped version, we derived equations for predicting the chromatic components of the HDR layer given the decoded LDR layer. Two color representations are studied. In a first encoding scheme, the HDR image is represented in the classical Y'CbCr format...
May 20, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28109633/the-american-college-of-radiology-and-the-american-brachytherapy-society-practice-parameter-for-the-performance-of-low-dose-rate-brachytherapy
#15
Akila N Viswanathan, Beth A Erickson, Geoffrey S Ibbott, William Small, Patricia J Eifel
Brachytherapy is the use of radionuclides to treat malignancies or benign conditions by means of a radiation source placed close to or into the tumor or treatment site. This practice parameter refers only to the use of radionuclide brachytherapy. Brachytherapy alone or combined with external beam therapy plays an important role in the management and treatment of patients with cancer. Low-dose-rate (LDR) brachytherapy has traditionally been used for treating prostate, head and neck, breast, cervical, and endometrial cancers as well as obstructive bile duct, esophageal, or bronchial lesions...
January 2017: Brachytherapy
https://www.readbyqxmd.com/read/28109632/the-american-college-of-radiology-and-the-american-brachytherapy-society-practice-parameter-for-transperineal-permanent-brachytherapy-of-prostate-cancer
#16
Nathan H J Bittner, Peter F Orio, Gregory S Merrick, Bradley R Prestidge, Alan Charles Hartford, Seth A Rosenthal
Transperineal permanent brachytherapy is a safe and effective treatment option for patients with organ-confined prostate cancer. Careful adherence to established brachytherapy standards has been shown to improve the likelihood of procedural success and reduce the incidence of treatment-related morbidity. A collaborative effort of the American College of Radiology (ACR) and the American Brachytherapy Society (ABS) has produced practice parameters for LDR prostate brachytherapy. These practice parameters define the qualifications and responsibilities of all the involved personnel, including the radiation oncologist, physicist and dosimetrist...
January 2017: Brachytherapy
https://www.readbyqxmd.com/read/28107729/recombinant-lh-supplementation-in-patients-with-a-relative-reduction-in-lh-levels-during-ivf-icsi-cycles-a-prospective-randomized-controlled-trial
#17
Robert Lahoud, John Ryan, Peter Illingworth, Frank Quinn, Michael Costello
PURPOSE: The aim of this study was to assess the use of recombinant luteinizing hormone (rLH) supplementation in patients who experience a reduction in LH concentration during controlled ovarian hyperstimulation (COH) for IVF/ICSI. METHODS: A multi-center prospective randomized controlled trial (RCT) was performed over three years. Two hundred and forty patients aged between 24 and 42 years undergoing IVF/ICSI treatment with a long down regulation (LDR) protocol were recruited...
January 9, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28104448/metformin-and-low-dose-radiation-modulates-cisplatin-induced-oxidative-injury-in-rat-via-ppar-%C3%AE-and-mapk-pathways
#18
Heba H Mansour, Shereen M El Kiki, Shereen M Galal
: Cisplatin (CIS) is a chemotherapeutic agent used for therapy of many tumors and has been limited by its toxicity. The aim of this study was to investigate the role of Peroxisome proliferator-activated receptor-gamma (PPAR-γ), mitogen-activated protein kinase (MAPK) and nuclear factor-kappa B(NFkB) in the pathogenesis of hepatic damage induced by CIS, and investigated the modulatory effect of metformin (MET) and/or low dose gamma radiation (LDR) on CIS-induced hepatotoxicity in rats...
January 16, 2017: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28102436/-urethral-stricture-rate-after-prostate-cancer-radiotherapy-five-year-data-of-a-certified-prostate-cancer-center
#19
J Kranz, G Maurer, U Maurer, O Deserno, S Schulte, J Steffens
BACKGROUND: A urethral stricture is a scar of the urethral epithelium which can cause obstructive voiding dysfunction with consequential damage of the upper urinary tract. Almost 45% of all strictures are iatrogenic; they develop in 2-9% of patients after radical prostatectomy, but can also occur after prostate cancer radiotherapy. This study provides 5‑year data of a certified prostate cancer center (PKZ) in terms of urethral strictures. MATERIALS AND METHODS: Between 01/2008 and 12/2012 a total of 519 men were irradiated for prostate cancer (LDR and HDR brachytherapy as well as external beam radiation)...
January 19, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28094209/simplified-low-dose-rate-infant-total-body-irradiation
#20
Nels Knutson, Y James Rao, Sridhar Yaddanapudi, Stephanie M Perkins, H Harold Li
PURPOSE: Low-dose-rate total body irradiation (LDR TBI) in infants possesses unique challenges because of the setup limitations imposed by anesthesia. We present an LDR TBI method with an anteroposterior/posteroanterior arrangement and dose rate < 10 cGy/minute for infants (thickness <14 cm) without the use of a beam attenuator. MATERIALS AND METHODS: The delivery used a 6 MV TrueBeam linear accelerator (Varian Medical Systems, Palo Alto, CA) with adjustable meterset rates below 100 MU/minute...
October 24, 2016: Practical Radiation Oncology
keyword
keyword
16098
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"