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https://www.readbyqxmd.com/read/29769101/a-new-strategy-for-volumetric-modulated-arc-therapy-planning-using-autoplanning-based-multicriteria-optimization-for-nasopharyngeal-carcinoma
#1
Juanqi Wang, Zhi Chen, Weiwei Li, Wei Qian, Xiaosheng Wang, Weigang Hu
BACKGROUND: A new strategy for making the appropriate choice of the representative optimization parameters in planning processes and accurate selection criteria during Pareto surface navigation for general multicriteria optimization (MCO) was recommended in the study. The purpose was to combine both benefits of AutoPlanning optimization and MCO (APMCO) for achieving an individual volumetric-modulated arc therapy (VMAT) plan according to the clinically achieved patient-specific tradeoff among conflicting priorities...
May 16, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29765265/is-volumetric-modulated-arc-therapy-with-constant-dose-rate-a-valid-option-in-radiation-therapy-for-head-and-neck-cancer-patients
#2
Annamaria Didona, Valentina Lancellotta, Claudio Zucchetti, Bianca Moira Panizza, Alessandro Frattegiani, Martina Iacco, Anna Concetta Di Pilato, Simonetta Saldi, Cynthia Aristei
Background: Intensity-modulated radiotherapy (IMRT) improves dose distribution in head and neck (HN) radiation therapy. Volumetric-modulated arc therapy (VMAT), a new form of IMRT, delivers radiation in single or multiple arcs, varying dose rates (VDR-VMAT) and gantry speeds, has gained considerable attention. Constant dose rate VMAT (CDR-VMAT) associated with a fixed gantry speed does not require a dedicated linear accelerator like VDR-VMAT. The present study explored the feasibility, efficiency and delivery accuracy of CDR-VMAT, by comparing it with IMRT and VDR-VMAT in treatment planning for HN cancer...
May 2018: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/29761987/-comparison-of-planning-quality-and-delivery-efficiency-between-volumetric-modulated-arc-therapy-and-dynamic-intensity-modulated-radiation-therapy-for-nasopharyngeal-carcinoma-with-more-than-4-prescribed-dose-levels
#3
Pengfei Jia, Jun Xu, Xiaoxi Zhou, Jian Chen, Lemin Tang
The aim of this study is to compare the planning quality and delivery efficiency between dynamic intensity modulated radiation therapy (d-IMRT) and dual arc volumetric modulated arc therapy (VMAT) systematically for nasopharyngeal carcinoma (NPC) patients with multi-prescribed dose levels, and to analyze the correlations between target volumes and plan qualities. A total of 20 patients of NPC with 4-5 prescribed dose levels to achieve simultaneous integrated boost (SIB) treated by sliding window d-IMRT in our department from 2014 to 2015 were re-planned with dual arc VMAT...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29760593/dosimetric-effect-of-limited-aperture-multileaf-collimator-on-vmat-plan-quality-a-study-of-prostate-and-head-and-neck-cancers
#4
Ghulam Murtaza, Shahid Mehmood, Shahid Rasul, Imran Murtaza, Ehsan Ullah Khan
Aim: The aim of study was to evaluate the dosimetric effect of collimator-rotation on VMAT plan quality, when using limited aperture multileaf collimator of Elekta Beam Modulator™ providing a maximum aperture of 21 cm × 16 cm. Background: The increased use of VMAT technique to deliver IMRT from conventional to very specialized treatments present a challenge in plan optimization. In this study VMAT plans were optimized for prostate and head and neck cancers using Elekta Beam-ModulatorTM , whereas previous studies were reported for conventional Linac aperture...
May 2018: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/29756264/study-design-and-early-result-of-a-phase-i-study-of-sabr-for-early-stage-glottic-cancer
#5
Tosol Yu, Chan Woo Wee, Noorie Choi, Hong-Gyun Wu, Hyun-Cheol Kang, Jong Min Park, Jung-In Kim, Jin Ho Kim, Tack-Kyun Kwon, Eun-Jae Chung
OBJECTIVE: Avoidance of organs at risk has become possible with advances in image-guided volumetric-modulated arc therapy (VMAT) techniques. This study was designed to evaluate the safety and feasibility of stereotactic ablative radiotherapy (SABR) for early stage glottic cancer. This report presents the preliminary result of the first and second dose level. METHODS: Fraction size was increased from 3.5 gray (Gy) (total dose 59.5 Gy) to 9 Gy (total dose 45 Gy). Dose-limiting toxicities were defined as grade 3 or higher treatment-related toxicities...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29753335/external-beam-planning-module-of-eclipse-for-external-beam-radiation-therapy
#6
REVIEW
Cheng B Saw, SiCong Li, Frank Battin, Janice McKeague, Christopher A Peters
Eclipse is a 3-dimensional (3D) treatment planning system for radiation therapy offered by Varian Medical Systems, Inc. The system has the network connectivity for the electronic transfer of image datasets and digital data communication among different equipment. The scope of this project for this special issue of Medical Dosimetry on 3D treatment planning systems is the assessment of planning tools in the external beam planning module of Eclipse to generate optimized treatment plans for patients undergoing external beam radiation therapy...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29753333/3d-treatment-planning-systems
#7
REVIEW
Cheng B Saw, Sicong Li
Three-dimensional (3D) treatment planning systems have evolved and become crucial components of modern radiation therapy. The systems are computer-aided designing or planning softwares that speed up the treatment planning processes to arrive at the best dose plans for the patients undergoing radiation therapy. Furthermore, the systems provide new technology to solve problems that would not have been considered without the use of computers such as conformal radiation therapy (CRT), intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT)...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29750173/radiotherapy-for-adult-medulloblastoma-evaluation-of-helical-tomotherapy-volumetric-intensity-modulated-arc-therapy-and-three-dimensional-conformal-radiotherapy-and-the-results-of-helical-tomotherapy-therapy
#8
Sun Zong-Wen, Yang Shuang-Yan, Du Feng-Lei, Cheng Xiao-Long, Li Qinglin, Chen Meng-Yuan, Hua Yong-Hong, Jin Ting, Hu Qiao-Ying, Chen Xiao-Zhong, Chen Yuan-Yuan, Chen Ming
Introduction: All adult medulloblastoma (AMB) patients should be treated with craniospinal irradiation (CSI) postoperatively. Because of the long irradiation range, multiple radiation fields must be designed for conventional radiotherapy technology. CSI can be completed in only one session with helical tomotherapy (HT). We evaluated the dose of HT, volumetric intensity modulated arc therapy (VMAT), and three-dimensional conformal radiotherapy (3D-CRT) of AMB and the results of 5 cases of AMB treated with HT...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29749075/evaluation-of-a-mixed-beam-therapy-for-post-mastectomy-breast-cancer-patients-bolus-electron-conformal-therapy-combined-with-intensity-modulated-photon-radiotherapy-and-volumetric-modulated-photon-arc-therapy
#9
Rui Zhang, David Heins, Mary Sanders, Beibei Guo, Kenneth Hogstrom
PURPOSE: The purpose of this study was to assess the potential benefits and limitations of a mixed beam therapy, which combined bolus electron conformal therapy (BECT) with intensity modulated photon radiotherapy (IMRT) and volumetric modulated photon arc therapy (VMAT), for left-sided post-mastectomy breast cancer patients. METHODS: Mixed beam treatment plans were produced for nine post-mastectomy radiotherapy (PMRT) patients previously treated at our clinic with VMAT alone...
May 10, 2018: Medical Physics
https://www.readbyqxmd.com/read/29745009/a-fast-jaw-tracking-model-for-vmat-and-imrt-monte-carlo-simulations
#10
Reid Townson, Hilary Egglestone, Sergei Zavgorodni
Modern radiotherapy techniques involve routine use of volumetric arc therapy (VMAT) and intensity modulated radiotherapy (IMRT) with jaw-tracking - dynamic motion of the secondary collimators (jaws) in tandem with multi-leaf collimators (MLCs). These modalities require accurate dose calculations for the purposes of treatment planning and dose verification. Monte Carlo (MC) methods for radiotherapy dose calculation are widely accepted as capable of achieving high accuracy. This paper presents an efficiency-enhancement method for secondary collimator modeling, presented in the context of a tool for MC-based dose second checks...
May 9, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29739713/volumetric-modulated-arc-therapy-of-head-and-neck-cancer-on-a-fast-rotating-o-ring-linac-plan-quality-and-delivery-time-comparison-with-a-c-arm-linac
#11
Steven Michiels, Kenneth Poels, Wouter Crijns, Laurence Delombaerde, Robin De Roover, Bianca Vanstraelen, Karin Haustermans, Sandra Nuyts, Tom Depuydt
BACKGROUND AND PURPOSE: Linac improvements in gantry speed, leaf speed and dose rate may increase the time-efficiency of volumetric modulated arc therapy (VMAT) delivery. The plan quality achievable with faster VMAT however remains to be investigated. In this study, a fast-rotating O-ring linac with fast-moving leaves is compared with a C-arm linac in terms of plan quality and delivery time for VMAT of head-and-neck cancer (HNC). MATERIAL AND METHODS: For 30 patients with HNC, treatment planning was performed using dual-arc (HA2) and triple-arc (HA3) VMAT on a Halcyon fast-rotating O-ring linac and using dual-arc VMAT on a TrueBeam C-arm linac (TB2)...
May 5, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29739431/optimal-collimator-rotation-based-on-the-outline-of-multiple-brain-targets-in-vmat
#12
Jung-In Kim, Beom Seok Ahn, Chang Heon Choi, Jong Min Park, So-Yeon Park
BACKGROUND: The aim of this study was to investigate the dosimetric quality in volumetric modulated arc therapy (VMAT) plans with optimal collimator angles that can represent the outline of multiple brain targets. METHODS: Twenty patients with multiple target volumes in the brain cases were selected retrospectively. To better represent the outline of the multiple brain targets, four conformal arc plans were generated for each patient using one full arc with four collimator settings...
May 9, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29730280/impact-of-database-quality-in-knowledge-based-treatment-planning-for-prostate-cancer
#13
Phillip D H Wall, Robert L Carver, Jonas D Fontenot
PURPOSE: This article investigates dose-volume prediction improvements in a common knowledge-based planning (KBP) method using a Pareto plan database compared with using a conventional, clinical plan database. METHODS AND MATERIALS: Two plan databases were created using retrospective, anonymized data of 124 volumetric modulated arc therapy (VMAT) prostate cancer patients. The clinical plan database (CPD) contained planning data from each patient's clinically treated VMAT plan, which were manually optimized by various planners...
March 13, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29728230/log-file-based-patient-dose-calculations-of-double-arc-vmat-for-head-and-neck-radiotherapy
#14
Yoshiyuki Katsuta, Noriyuki Kadoya, Yukio Fujita, Eiji Shimizu, Kazuhiro Majima, Haruo Matsushita, Ken Takeda, Keiichi Jingu
PURPOSE: The log file-based method cannot display dosimetric changes due to linac component miscalibration because of the insensitivity of log files to linac component miscalibration. The purpose of this study was to supply dosimetric changes in log file-based patient dose calculations for double-arc volumetric-modulated arc therapy (VMAT) in head-and-neck cases. METHODS AND MATERIALS: Fifteen head-and-neck cases participated in this study. For each case, treatment planning system (TPS) doses were produced by double-arc and single-arc VMAT...
April 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29728225/plan-quality-and-robustness-in-field-junction-region-for-craniospinal-irradiation-with-vmat
#15
Keqiang Wang, Huipeng Meng, Jie Chen, Wenxue Zhang, Yuanming Feng
PURPOSE: To propose a "staggered overlap" technique in volumetric modulated arc therapy (VMAT) for craniospinal irradiation (CSI) and compare the dose distribution and plan robustness with "overlap" technique and "gradient optimization" approach. METHODS AND MATERIALS: 6 patients previously treated in our clinic were retrospectively selected. 9 VMAT plans of each patient were optimized with "staggered overlap", "overlap" and "gradient optimization" in overlapping region of 3 cm, 6 cm, and 9 cm separately...
April 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29715081/estimation-of-risk-of-normal-tissue-toxicity-following-gastric-cancer-radiotherapy-with-photon-or-scanned-proton-beams
#16
Gracinda Mondlane, Ana Ureba, Michael Gubanski, Pehr A Lind, Albert Siegbahn
BACKGROUND/AIM: Gastric cancer (GC) radiotherapy involves irradiation of large tumour volumes located in the proximities of critical structures. The advantageous dose distributions produced by scanned-proton beams could reduce the irradiated volumes of the organs at risk (OARs). However, treatment-induced side-effects may still appear. The aim of this study was to estimate the normal tissue complication probability (NTCP) following proton therapy of GC, compared to photon radiotherapy...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29714714/a-novel-approach-to-epid-based-3d-volumetric-dosimetry-for-imrt-and-vmat-qa
#17
Abdulaziz Alhazmi, Chiara Gianoli, Sebastian Neppl, Juliana Martins, Stella Veloza, Mark Podesta, Frank Verhaegen, Michael Reiner, Claus Belka, Katia Parodi
Intensity Modulated Radiation Therapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) are relatively complex treatment delivery techniques and require Quality Assurance (QA) procedures. Pre-treatment dosimetric verification represents a fundamental QA rocedure in daily clinical routine in radiation therapy. The purpose of this study is to develop an EPID-based approach to reconstruct a 3D dose distribution as imparted to a virtual cylindrical water phantom to be used for plan-specific pre-treatment dosimetric verification for IMRT and VMAT plans...
May 1, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29708544/radiation-planning-assistant-a-streamlined-fully-automated-radiotherapy-treatment-planning-system
#18
Laurence E Court, Kelly Kisling, Rachel McCarroll, Lifei Zhang, Jinzhong Yang, Hannah Simonds, Monique du Toit, Chris Trauernicht, Hester Burger, Jeannette Parkes, Mike Mejia, Maureen Bojador, Peter Balter, Daniela Branco, Angela Steinmann, Garrett Baltz, Skylar Gay, Brian Anderson, Carlos Cardenas, Anuja Jhingran, Simona Shaitelman, Oliver Bogler, Kathleen Schmeller, David Followill, Rebecca Howell, Christopher Nelson, Christine Peterson, Beth Beadle
The Radiation Planning Assistant (RPA) is a system developed for the fully automated creation of radiotherapy treatment plans, including volume-modulated arc therapy (VMAT) plans for patients with head/neck cancer and 4-field box plans for patients with cervical cancer. It is a combination of specially developed in-house software that uses an application programming interface to communicate with a commercial radiotherapy treatment planning system. It also interfaces with a commercial secondary dose verification software...
April 11, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29703705/integration-of-radiobiological-modeling-and-indices-in-comparative-plan-evaluation-a-study-comparing-vmat-and-3d-crt-in-patients-with-nsclc
#19
Soumyajit Roy, Iulian Badragan, Sheikh Nisar Ahmed, Michael Sia, Jorawur Singh, Gaurav Bahl
PURPOSE: The purpose of this article was to generate an algorithm to calculate radiobiological endpoints and composite indices and use them to compare volumetric modulated arc therapy (VMAT) and 3-dimensional conformal radiation therapy (3D-CRT) techniques in patients with locally advanced non-small cell lung cancer. METHODS AND MATERIALS: The study included 25 patients with locally advanced non-small cell lung cancer treated with 3D-CRT at our center between January 1, 2010, and December 31, 2014...
March 1, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29698060/dosimetric-comparison-of-five-different-techniques-for-craniospinal-irradiation-across-15-european-centers-analysis-on-behalf-of-the-siop-e-btg-radiotherapy-working-group
#20
Enrica Seravalli, Mirjam Bosman, Yasmin Lassen-Ramshad, Anne Vestergaard, Foppe Oldenburger, Jorrit Visser, Efi Koutsouveli, Chryssa Paraskevopoulou, Gail Horan, Thankamma Ajithkumar, Beate Timmermann, Carolina-Sofia Fuentes, Gillian Whitfield, Thomas Marchant, Laetitia Padovani, Eloise Garnier, Lorenza Gandola, Silvia Meroni, Bianca A W Hoeben, Martijn Kusters, Claire Alapetite, Sandra Losa, Farid Goudjil, Henriette Magelssen, Morten Egeberg Evensen, Frank Saran, Gregory Smyth, Barbara Rombi, Roberto Righetto, Rolf-Dieter Kortmann, Geert O Janssens
PURPOSE: Conventional techniques (3D-CRT) for craniospinal irradiation (CSI) are still widely used. Modern techniques (IMRT, VMAT, TomoTherapy® , proton pencil beam scanning [PBS]) are applied in a limited number of centers. For a 14-year-old patient, we aimed to compare dose distributions of five CSI techniques applied across Europe and generated according to the participating institute protocols, therefore representing daily practice. MATERIAL AND METHODS: A multicenter (n = 15) dosimetric analysis of five different techniques for CSI (3D-CRT, IMRT, VMAT, TomoTherapy® , PBS; 3 centers per technique) was performed using the same patient data, set of delineations and dose prescription (36...
April 26, 2018: Acta Oncologica
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