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https://www.readbyqxmd.com/read/27929514/evaluation-of-kidney-motion-and-target-localization-in-abdominal-sbrt-patients
#1
Marcus Sonier, William Chu, Nafisha Lalani, Darby Erler, Patrick Cheung, Renee Korol
The purpose of this study was to evaluate bilateral kidney and target translational/rotational intrafraction motion during stereotactic body radiation therapy treatment delivery of primary renal cell carcinoma and oligometastatic adrenal lesions for patients immobilized in the Elekta BodyFIX system. Bilateral kidney motion was assessed at midplane for 30 patients immobilized in a full-body dual-vacuum-cushion system with two patients immobilized via abdominal compression. Intrafraction motion was assessed for 15 patients using kilovoltage cone-beam computed tomography (kV-CBCT) datasets (n = 151) correlated to the planning CT...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929512/a-survey-on-table-tolerances-and-couch-overrides-in-radiotherapy
#2
Bonnie Chinsky, Rakesh Patel, Joshua Panfil, Murat Surucu, John C Roeske
The purpose of this study was to survey current departmental policies on treatment couch overrides and the values of table tolerances used clinically. A 25-question electronic survey on couch overrides and tolerances was sent to full members of the American Association of Physicists in Medicine (AAPM). The first part of the survey asked participants if table overrides were allowed at their institution, who was allowed to perform these overrides, and if imaging was required with overrides. The second part of the survey asked individuals to provide table tolerance data for the following treatment sites: brain/head and neck (H&N), lung, breast, abdo-men/pelvis and prostate...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929504/gafchromic-ebt-xd-film-dosimetry-characterization-in-high-dose-volumetric-modulated-arc-therapy
#3
Hideharu Miura, Shuichi Ozawa, Fumika Hosono, Naoki Sumida, Toshiya Okazue, Kiyoshi Yamada, Yasushi Nagata
Radiochromic films are important tools for assessing complex dose distributions. Gafchromic EBT-XD films have been designed for optimal performance in the 40-4,000 cGy dose range. We investigated the dosimetric characteristics of these films, including their dose-response, postexposure density growth, and dependence on scanner orientation, beam energy, and dose rate with applications to high-dose volumetric-modulated arc therapy (VMAT) verification. A 10 MV beam from a TrueBeam STx linear accelerator was used to irradiate the films with doses in the 0-4,000 cGy range...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929501/volumetric-modulated-arc-therapy-using-multicriteria-optimization-for-body-and-extremity-sarcoma
#4
Michael R Young, David L Craft, Caroline M Colbert, Kyla Remillard, Liam Vanbenthuysen, Yi Wang
This study evaluates the implementation of volumetric-modulated arc therapy (VMAT) using multicriteria optimization (MCO) in the RayStation treatment planning system (TPS) for complex sites, namely extremity and body sarcoma. The VMAT-MCO algorithm implemented in RayStation is newly developed and requires an integrated, comprehensive analysis of plan generation, delivery, and treatment efficiency. Ten patients previously treated by intensity-modulated radiation therapy (IMRT) with MCO were randomly selected and replanned using VMAT-MCO...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929499/development-and-evaluation-of-a-clinical-model-for-lung-cancer-patients-using-stereotactic-body-radiotherapy-sbrt-within-a-knowledge-based-algorithm-for-treatment-planning
#5
Karen Chin Snyder, Jinkoo Kim, Anne Reding, Corey Fraser, James Gordon, Munther Ajlouni, Benjamin Movsas, Indrin J Chetty
The purpose of this study was to describe the development of a clinical model for lung cancer patients treated with stereotactic body radiotherapy (SBRT) within a knowledge-based algorithm for treatment planning, and to evaluate the model performance and applicability to different planning techniques, tumor locations, and beam arrangements. 105 SBRT plans for lung cancer patients previously treated at our institution were included in the development of the knowledge-based model (KBM). The KBM was trained with a combination of IMRT, VMAT, and 3D CRT techniques...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929498/dosimetric-comparison-of-intensity-modulated-radiotherapy-and-volumetric-modulated-arc-radiotherapy-in-patients-with-prostate-cancer-a-meta-analysis
#6
Wenting Ren, Chao Sun, Ningning Lu, Yingjie Xu, Fei Han, Yue Ping Liu, Jianrong Dai
Intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) are two main radiotherapy techniques. The aim of this study is to explore which is the preferred technique in prostate treatment through the related publica-tions and meta-analysis. Two authors independently identified all relevant articles available regarding eligibility criteria on PubMed, Embase, and Cochrane Library databases until December 2015. Publication bias was evaluated with funnel plot, and statistical analyses were performed with Stata software...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929493/application-programming-in-c-environment-with-recorded-user-software-interactions-and-its-application-in-autopilot-of-vmat-imrt-treatment-planning
#7
Henry Wang, Lei Xing
An autopilot scheme of volumetric-modulated arc therapy (VMAT)/intensity-modulated radiation therapy (IMRT) planning with the guidance of prior knowl-edge is established with recorded interactions between a planner and a commercial treatment planning system (TPS). Microsoft (MS) Visual Studio Coded UI is applied to record some common planner-TPS interactions as subroutines. The TPS used in this study is a Windows-based Eclipse system. The interactions of our application program with Eclipse TPS are realized through a series of subrou-tines obtained by prerecording the mouse clicks or keyboard strokes of a planner in operating the TPS...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929490/rounded-leaf-end-modeling-in-pinnacle-vmat-treatment-planning-for-fixed-jaw-linacs
#8
Lori A Young, Fei Yang, Ning Cao, Juergen Meyer
During volume-modulated arc therapies (VMAT), dosimetric errors are introduced by multiple open dynamic leaf gaps that are present in fixed diaphragm linear accelerators. The purpose of this work was to develop a methodology for adjusting the rounded leaf end modeling parameters to improve out-of-field dose agreement in SmartArc VMAT treatment plans delivered by fixed jaw linacs where leaf gap dose is not negligible. Leaf gap doses were measured for an Elekta beam modulator linac with 0.4 cm micro-multileaf collimators (MLC) using an A16 micro-ionization chamber, a MatriXX ion chamber detector array, and Kodak EDR2 film dosimetry in a solid water phantom...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929483/a-dosimetric-evaluation-of-knowledge-based-vmat-planning-with-simultaneous-integrated-boosting-for-rectal-cancer-patients
#9
Hao Wu, Fan Jiang, Haizhen Yue, Sha Li, Yibao Zhang
RapidPlan, a commercial knowledge-based optimizer, has been tested on head and neck, lung, esophageal, breast, liver, and prostate cancer patients. To appraise its performance on VMAT planning with simultaneous integrated boosting (SIB) for rectal cancer, this study configured a DVH (dose-volume histogram) estimation model consisting 80 best-effort manual cases of this type. Using the model-generated objectives, the MLC (multileaf collimator) sequences of other 70 clinically approved plans were reoptimized, while the remaining parameters, such as field geometry and photon energy, were maintained...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27919621/a-comparative-study-of-standard-intensity-modulated-radiotherapy-and-rapidarc-planning-techniques-for-ipsilateral-and-bilateral-head-and-neck-irradiation
#10
Jennifer Pursley, Antonio L Damato, Maria A Czerminska, Danielle N Margalit, David J Sher, Roy B Tishler
The purpose of this study was to investigate class solutions using RapidArc volumetric-modulated arc therapy (VMAT) planning for ipsilateral and bilateral head and neck (H&N) irradiation, and to compare dosimetric results with intensity-modulated radiotherapy (IMRT) plans. A total of 14 patients who received ipsilateral and 10 patients who received bilateral head and neck irradiation were retrospectively replanned with several volumetric-modulated arc therapy techniques. For ipsilateral neck irradiation, the volumetric-modulated arc therapy techniques included two 360° arcs, two 360° arcs with avoidance sectors around the contralateral parotid, two 260° or 270° arcs, and two 210° arcs...
December 2, 2016: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/27914680/comparison-of-toxicity-and-outcome-in-advanced-stage-non-small-cell-lung-cancer-patients-treated-with-intensity-modulated-chemo-radiotherapy-using-imrt-or-vmat
#11
Robin Wijsman, Frank Dankers, Esther G C Troost, Aswin L Hoffmann, Erik H F M van der Heijden, Lioe-Fee de Geus-Oei, Johan Bussink
Retrospective evaluation of 188 advanced stage non-small cell lung cancer patients treated with IMRT or VMAT revealed a limited increase of moderate to severe acute esophageal toxicity after VMAT. Acute pulmonary toxicity and severe late toxicity were low. Overall survival did not differ between the IMRT and VMAT groups.
November 30, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27908453/volumetric-modulated-arc-therapy-with-dynamic-collimator-rotation-for-improved-multileaf-collimator-tracking-of-the-prostate
#12
Ghulam Murtaza, Jakob Toftegaard, Ehsan Ullah Khan, Per Rugaard Poulsen
PURPOSE: To improve MLC tracking of prostate VMAT plans by dynamic rotation of the collimator to align the MLC leaves with the dominant prostate motion direction. METHODS: For 22 prostate cancer patients, two dual arc VMAT plans were made with (1) fixed collimators (45° and 315°) and (2) a rotating collimator that aligned the MLC leaves with the dominant prostate motion direction (population-based first principal component). The fixed and rotating collimator plan quality was compared using selected dose-volume indices...
November 28, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27903198/dosimetric-characterization-of-hypofractionated-gamma-knife-radiosurgery-of-large-or-complex-brain-tumors-versus-linear-accelerator-based-treatments
#13
Peng Dong, Angélica Pérez-Andújar, Dilini Pinnaduwage, Steve Braunstein, Philip Theodosopoulos, Michael McDermott, Penny Sneed, Lijun Ma
OBJECTIVE Noninvasive Gamma Knife (GK) platforms, such as the relocatable frame and on-board imaging, have enabled hypofractionated GK radiosurgery of large or complex brain lesions. This study aimed to characterize the dosimetric quality of such treatments against linear accelerator-based delivery systems that include the CyberKnife (CK) and volumetric modulated arc therapy (VMAT). METHODS Ten patients treated with VMAT at the authors' institution for large brain tumors (> 3 cm in maximum diameter) were selected for the study...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27885857/dosimetric-trade-offs-in-breast-treatment-with-vmat-technique
#14
Antonella Fogliata, Jan Seppälä, Giacomo Reggiori, Francesca Lobefalo, Valentina Palumbo, Fiorenza De Rose, Davide Franceschini, Marta Scorsetti, Luca Cozzi
OBJECTIVES: Breast planning with volumetric modulated arc therapy (VMAT) has been explored, especially for left sided breast treatments, with the primary intent of lowering the heart dose and improving target dose homogeneity. As a trade-off, larger healthy tissue volumes would receive low dose levels, with the potential risk of increasing late toxicities and secondary cancer induction, although no clinical data are today available to confirm the risk level. Scope of this work is to explore the dosimetric trade-offs using two different VMAT planning...
November 25, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27885855/frameless-stereotactic-volumetric-modulated-arc-radiotherapy-of-brachial-plexus-tumours-in-dogs-10-cases
#15
Mario Dolera, Luca Malfassi, Cristina Bianchi, Nancy Carrara, Sara Finesso, Silvia Marcarini, Giovanni Mazza, Simone Pavesi, Massimo Sala, Gaetano Urso
OBJECTIVES: Treatment of canine peripheral nerve sheath tumours (PNSTs) is challenging, and prognosis after surgical resection is considered poor. The aim of this study was to evaluate the feasibility and the effectiveness of stereotactic radiotherapy of these tumours. METHODS: Ten dogs with clinical symptoms and MRI findings consistent with PNSTs of the brachial plexus, branches and nerve roots were treated with LINAC-based volumetric modulated arc radiotherapy (VMAT) with a dose of 35 Gy/5 fractions...
November 25, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27881285/conventionally-fractionationed-volumetric-arc-therapy-versus-hypofractionated-stereotactic-body-radiotherapy-quality-of-life-side-effects-and-prostate-specific-antigen-kinetics-in-localized-prostate-cancer
#16
Makbule Tambas, Fulya Agaoglu, Ayca Iribas, Murat Guveli, Yavuz Dizdar, Murat Okutan, Dilek Sahin, Nuri Tenekeci, Emin Darendeliler
OBJECTIVES: To compare conventionally fractionationed volumetric arc therapy (VMAT) and hypofractionated stereotactic body radiotherapy (SBRT) modalities in terms of prostate-specific antigen (PSA) kinetics, toxicity, and quality of life (QOL) in patients with localized prostate cancer. METHODS: Patients received radical radiotherapy as either 33.5 Gy/5 fr for SBRT or 75.6 Gy/35 fr for VMAT. International Prostate Symptom Score (IPSS) and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Prostate Cancer Module (QLQ-PR25) forms were used to assess QOL...
September 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27881187/class-solutions-for-sabr-vmat-for-high-risk-prostate-cancer-with-and-without-elective-nodal-irradiation
#17
Sarah O S Osman, Prakash Jeevanandam, Nithya Kanakavelu, Denise M Irvine, Ciara A Lyons, Suneil Jain, Alan R Hounsell, Conor K McGarry
BACKGROUND: The purpose of this study is to find the optimal planning settings for prostate SABR-VMAT for high-risk prostate cancer patients irradiated to prostate only (PO) or prostate and pelvic lymph nodes (PPLN). METHODS: For 10 patients, plans using 6MV flattened, flattening-filter-free (FFF) 6MV (6 F) and FFF 10MV (10 F) photon beams with full and partial arc arrangements were generated and compared. The prescribed dose was 40Gy to the prostate with 25Gy to the PLN in 5 fractions...
November 24, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27875568/gated-volumetric-modulated-arc-therapy-vs-tumor-tracking-cyberknife-radiotherapy-as-stereotactic-body-radiotherapy-for-hepatocellular-carcinoma-a-dosimetric-comparison-study-focused-on-the-impact-of-respiratory-motion-managements
#18
KyoungJun Yoon, Jungwon Kwak, Byungchul Cho, Jin-Hong Park, Sang Min Yoon, Sang-Wook Lee, Jong Hoon Kim
PURPOSE: To assess the potential dosimetric benefits associated with the CyberKnife (CK) tumor tracking capability, wherein an extra margin for respiratory tumor motion is not required, when compared to respiratory-gated volumetric-modulated arc therapy (VMAT) for hepatocellular carcinoma (HCC). METHODS: Twenty-nine HCC patients previously treated with double-arc VMAT were enrolled. In each VMAT plan, the individual internal target volume (ITV) margin around the tumor was determined by measuring its motion over 30-70% of respiratory phases using four-dimensional computed tomography, followed by a 5-mm isotropic margin for the planning target volume (PTV)...
2016: PloS One
https://www.readbyqxmd.com/read/27870878/3d-vmat-verification-based-on-monte-carlo-log-file-simulation-with-experimental-feedback-from-film-dosimetry
#19
A R Barbeiro, A Ureba, J A Baeza, R Linares, M Perucha, E Jiménez-Ortega, S Velázquez, J C Mateos, A Leal
A model based on a specific phantom, called QuAArC, has been designed for the evaluation of planning and verification systems of complex radiotherapy treatments, such as volumetric modulated arc therapy (VMAT). This model uses the high accuracy provided by the Monte Carlo (MC) simulation of log files and allows the experimental feedback from the high spatial resolution of films hosted in QuAArC. This cylindrical phantom was specifically designed to host films rolled at different radial distances able to take into account the entrance fluence and the 3D dose distribution...
2016: PloS One
https://www.readbyqxmd.com/read/27867173/evaluation-of-in-vivo-volumetric-dosimetry-for-prostate-cancer-using-electronic-portal-imaging-device
#20
Toshikazu Imae, Shigeharu Takenaka, Yuuichi Watanabe, Yukari Okano, Makoto Nedu, Shigeki Saegusa, Yukihiro Takeuchi, Keiichi Yano, Akihiro Haga, Kenshirou Shiraishi, Hideomi Yamashita, Keiichi Nakagawa
PURPOSE: Volumetric modulated arc therapy (VMAT) is capable of acquiring projection images using electronic portal imaging device (EPID). Commercial EPID-based dosimetry software, dosimetry check (DC), allows in vivo dosimetry using projection images. The purpose of this study was to evaluate in vivo dosimetry for prostate cancer using VMAT. METHOD: VMAT plans were generated for eight patients with prostate cancer using treatment planning system (TPS), and patient quality assurances (QAs) were carried out with phantom...
2016: Nihon Hoshasen Gijutsu Gakkai Zasshi
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