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Experimental burn

F Mashayeky Rad, S Spinicci, S Silvergren, U Nilsson, R Westerholm
In the present study, a methodology involving hydrophilic interaction liquid chromatography (HILIC) and electrospray (ESI) tandem mass spectrometry (MS/MS) was developed for measurement of anhydrous monosaccharides as markers for wood burning in atmospheric aerosols, PM10 . No extensive sample preparation, other than ultrasound-assisted solvent extraction and evaporation, was applied. A pentahydroxysilica column enabled separation of levoglucosan from mannosan and galactosan within 5 min and the quantitative performance was validated using the standard reference materials (SRM) 1649a and 1649b...
August 1, 2018: Chemosphere
Mustafa Onur Oztan, Fatma Demet Arslan, Sule Oztan, Gulden Diniz, Gokhan Koyluoglu
BACKGROUND: Caustic esophageal burn is still an important health problem in pediatric surgery. Although there are a number of experimental and clinical studies to increase the recovery of the esophagus and reduce the stenosis rate, there is no consensus on the treatment protocol. Platelet-rich plasma (PRP) is an autologous blood product, which has positive effects on wound healing, reepithelization and scar prevention. The aim of our study was to investigate the effects of PRP on stricture formation and oxidative status after caustic esophageal injury in rats...
August 1, 2018: Journal of Pediatric Surgery
Kitti Rusznák, Kata Csekő, Zsófia Varga, Dávid Csabai, Ágnes Bóna, Mátyás Mayer, Zsolt Kozma, Zsuzsanna Helyes, Boldizsár Czéh
Marijuana is a widely used recreational drug with increasing legalization worldwide for medical purposes. Most experimental studies use either synthetic or plant-derived cannabinoids to investigate the effect of cannabinoids on anxiety and cognitive functions. The aim of this study was to mimic real life situations where young people smoke cannabis regularly to relax from everyday stress. Therefore, we exposed young adult male NMRI mice to daily stress and concomitant marijuana smoke for 2 months and investigated the consequences on physiology, behavior and adult hippocampal neurogenesis...
2018: Frontiers in Pharmacology
Hannah B Vander Zanden, Abigail Reid, Todd Katzner, David M Nelson
RATIONALE: Stable hydrogen isotope (δ2 H) ratios of animal tissues are useful for assessing movement and geographic origin of mobile organisms. However, it is uncertain whether heat and singeing affects feather δ2 H values and thus subsequent geographic assignments. This is relevant for birds of conservation interest that are burned and killed at concentrating solar-energy facilities that reflect sunlight to a receiving tower and generate a solar flux field. METHODS: We used a controlled experiment to test the effect of known heat loads (exposure to 200, 250 or 300 °C for one minute) on the morphology and δ2 H values of feathers from two songbird species...
August 3, 2018: Rapid Communications in Mass Spectrometry: RCM
Sima Bakht Azad, Iraj Nikokar, Sobhan Faezi, Soheila Rasooly, Mehdi Mahdavi
Considering the increased antibiotic resistance of Pseudomonas aeruginosa, the evaluation of immune response against the antigens of this bacterium seems necessary. In this study, the protective efficacy and immunological properties of P. aeruginosa recombinant PilQ (r-PilQ) and type b-flagellin (FLB) proteins was evaluated in the burn mouse model of infection. The inbred BALB/c mice were immunized with r-PilQ and FLB antigens. To investigate the type of induced immune response, sera were analyzed by ELISA for total IgG, IgG1, and IgG2a isotypes...
July 31, 2018: Microbial Pathogenesis
P Cui, H M Xin, Q Zhan, Z P Tang, C J Deng, X H Li, Y H Lai, R S Li, A N Chen, Y L Tong
Objective: To explore mechanism of lung injury of rats induced by inhalation of white smoke from burning smoke pot. Methods: Forty-eight Sprague Dawley rats were divided into control group ( n =12) and injury group ( n =36) according to the random number table. Rats in injury group were placed in smoke-induced injury experimental equipment fulled with white smoke from burning smoke pot for 5 minutes to make lung injury, and rats in control group were placed in smoke-induced injury experimental equipment fulled with air for 5 minutes to make sham injury...
July 20, 2018: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
Y S Huang, G X Xiao, S L Wang, Y Z Peng
Burn medicine of China started in 1958. Great progress has been achieved in discipline construction, scientific research, clinical treatment level, and talent team construction in 60 years. A large number of severely burned patients have been successfully treated, and plans for treatment of burn patients with Chinese characteristics have been established with world-leading treatment level. At the same time, in the continuous improvement of clinical treatment level, extensive experimental researches for the key scientific problems in clinical treatment of burn patients have been conducted, and a large number of innovative research results have been achieved by Chinese burn medicine workers...
July 20, 2018: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
Anju Yadav, Saurabh Verma, Gaurav K Keshri, Asheesh Gupta
Burn wound is a complex multi-factorial pathophysiology producing excruciating pain and psychological discomfort among patients, which imposes a major burden on the healthcare system. Multi-target therapy focuses on augmented healing by regulating different phases of tissue repair. Recently, photobiomodulation (PBM)-induced wound healing has achieved profound impetus as a non-invasive, drug-free biophysical therapeutic approach. On the other hand, medicinal honey known to possess antibacterial and immunomodulatory properties and is being used as an effective treatment option for infected wounds...
September 2018: Journal of Photochemistry and Photobiology. B, Biology
Caroline Bodi Winn, Stephen C Artim, Morgan S Jamiel, Monika A Burns, Jennifer L Haupt, James G Fox, Sureshkumar Muthupalani
A 6-y-old, intact, pair-housed male common marmoset (Callithrix jacchus) presented with acute onset dyspnea and tachypnea immediately after sedation with alfaxalone; a history of gradual weight loss initiated the examination under sedation. Thoracic radiographs revealed significant right-lung consolidation, with a vesicular gas pattern in the right caudodorsal lung field, pleural effusion, and dorsal displacement of the heart. The marmoset was euthanized due to his unstable condition and poor prognosis. At necropsy, the cranial and middle lobes of the right lung were homogenously dark red-brown, enlarged, edematous, and twisted around the longitudinal axis at the hilus...
July 16, 2018: Comparative Medicine
Leonie S Taams, Kathryn J A Steel, Ushani Srenathan, Lachrissa A Burns, Bruce W Kirkham
Spondyloarthritis (SpA) is a term that refers to a group of inflammatory diseases that includes psoriatic arthritis, axial SpA and nonradiographic axial SpA, reactive arthritis, enteropathic arthritis and undifferentiated SpA. The disease subtypes share clinical and immunological features, including joint inflammation (peripheral and axial skeleton); skin, gut and eye manifestations; and the absence of diagnostic autoantibodies (seronegative). The diseases also share genetic factors. The aetiology of SpA is still the subject of research by many groups worldwide...
July 13, 2018: Nature Reviews. Rheumatology
Katherine Kral, Ryan Limb, Amy Ganguli, Torre Hovick, Kevin Sedivec
Global biodiversity is threatened by invasive plant species. Without a thorough understanding of effective management strategies, minimizing their impacts while improving native species diversity will be challenging. Burning in fire-prone landscapes has been successful for managing invasive species and increasing native biodiversity, but it is unclear how specific fire regimes improve restoration practices in novel ecosystems where invasive plants have a similar growth phenology to native plants. We investigated fire as a restoration practice in the Northern Great Plains to decrease the cover of Kentucky bluegrass Poa pratensis (bluegrass), a perennial cool-season invasive grass phenologically similar to dominant native cool-season grasses, by 1) evaluating season of burn (early-growing season, late-growing season, and dormant season) in a field experiment to test differences in plant community composition and 2) manipulating fine fuels (3000-5000 kg ha-1 ) in an experimental approach to determine the effects of fire on plant survivability of selected native grasses and bluegrass...
October 1, 2018: Journal of Environmental Management
Edivaldo L Thomaz
Areas subjected to fire have a two-layer system (i.e., ash and soil), which brings enormous complexities to hydrogeomorphic processes. In addition, the combinations of variables from the ash and the soil characteristics result in several possible two-layer system contexts. Here, the interactions among ash and microaggregates (i.e., ash placed over fine soil microaggregates) and their effects on hydro-erosional processes are explored. The ash was produced by an experimental fire and collected from a field managed by a slash-and-burn agricultural system...
June 1, 2018: Science of the Total Environment
Ruby Peters, Juliette Griffié, Garth L Burn, David J Williamson, Dylan M Owen
Single molecule localization microscopy (SMLM) methods produce data in the form of a spatial point pattern (SPP) of all localized emitters. Whilst numerous tools exist to quantify molecular clustering in SPP data, the analysis of fibrous structures has remained understudied. Taking the SMLM localization coordinates as input, we present an algorithm capable of tracing fibrous structures in data generated by SMLM. Based upon a density parameter tracing routine, the algorithm outputs several fibre descriptors, such as number of fibres, length of fibres, area of enclosed regions and locations and angles of fibre branch points...
July 10, 2018: Scientific Reports
Mojgan Lotfi, Akram Ghahremaneian, Ahmad Aghazadeh, Fatemeh Jamshidi
Introduction: Many physical, psychological, social and economic complications have been reported after discharge, which have a negative impact on the quality of life of burn patients. The present research examines the effect of pre-discharge training program on the life quality of patients with burns. Methods: This is a pre and post-experimental study with control group that was conducted in 2015 in teaching hospital Sina. The control group received the typical instructions upon being discharged from hospital while the experimental group received in-person training in the form of question-answer, pamphlets and a researcher-made instruction booklet...
June 2018: Journal of Caring Sciences
Jing Liu, Lingling Peng, Yale Liu, Kunyi Wu, Sijia Wang, Xuening Wang, Qilu Liu, Yumin Xia, Weihui Zeng
The interaction of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor fibroblast growth factor inducible 14 (Fn14) participates in inflammatory responses, fibrosis, and tissue remodeling, which are central in the repair processes of wounds. Fn14 is expressed in main skin cells including dermal fibroblasts. This study was designed to explore the therapeutic effect of TWEAK on experimental burn wounds and the relevant mechanism underlying such function. Third-degree burns were introduced in two BALB/c mouse strains...
2018: Frontiers in Pharmacology
Paola M Tricarico, Luisa Zupin, Giulia Ottaviani, Sabrina Pacor, Francette Jean-Louis, Michele Boniotto, Sergio Crovella
Mutations in NCSTN gene (encoding for nicastrin protein) are associated with hidradenitis suppurativa (HS), a chronic inflammatory disease involving hair follicles. HS is clinically handled with drugs but the most severe cases are treated with surgery. Photobiomodulation (PBM) therapy, already used in the treatment of skin diseases such as acne, herpes virus lesions, ultraviolet damage, vitiligo, hypertrophic scar, keloid, burn, psoriasis and diabetic chronic wounds, could be beneficial as an adjuvant supportive treatment to promote and foster the healing process after skin excision in HS...
July 2, 2018: Journal of Biophotonics
Xiao Peng, Fengnan Guo, Xuan Zhang, Ning Shi, Yan Wu
In the aim of BTEX leakage emergency, monolithic carbon foam (MCF) was designed and prepared via a simple method. Rice husk char (RHC) was chosen as raw material, polyurethane sponge (PUS) was used as sacrificed template to form inner channel, and corn starch and ZnO were employed as binder and reinforcing filler, respectively. The optimized preparation parameter was determined by adopting of Taguchi experimental design method. Both MCF-RHC and MCF-CAC were made from RHC and commercial activated carbon (CAC) under the same condition, and three reported monolithic carbon adsorbents were selected for comparative study with MCFs...
July 3, 2018: Environmental Science and Pollution Research International
Cheng-Miao Jin, Min Cui, Yong Han, Ying-Jun Chen, Jiao Tang, Jun Li, Gan Zhang
Forest vegetation burning is an important source of atmospheric particulates. In this study, 22 kinds of typical tropical trees in Southeast Asia, which can be divided into evergreen trees, deciduous trees, and shrubs, were selected for experimentation. The emission characteristics of dehydrated sugar, acephenanthrylene, aceanthrylene, and retene were analyzed. The trend of the average emission factor for total sugar was evergreen trees (1.56 g·kg-1 ±1.01 g·kg-1 ) < shrubs (1.99 g·kg-1 ±0.64 g·kg-1 ) < deciduous trees (5...
June 8, 2018: Huan Jing Ke Xue= Huanjing Kexue
Motoki Kida, Daisuke Shimoyama, Toshiaki Ikeda, Ryo Sekiya, Takeharu Haino, Takayuki Ebata, Christophe Jouvet, Yoshiya Inokuchi
We observe UV spectra of protonated dibenzylamine (dBAMH+) and its complexes with 15-crown-5 (dBAMH+-15C5), 18-crown-6 (dBAMH+-18C6), and 24-crown-8 (dBAMH+-24C8) under cold (∼10 K) gas-phase conditions by UV photodissociation (UVPD) and UV-UV hole-burning (HB) spectroscopy. The UVPD spectrum of the dBAMH+-15C5 complex shows an extensive low-frequency progression, which originates from a unique conformation of the dBAMH+ part with benzene rings facing closely to each other, while UVPD and calculation results suggest open conformations of the dBAMH+ part for dBAMH+-18C6 and dBAMH+-24C8...
July 11, 2018: Physical Chemistry Chemical Physics: PCCP
Mustafa Onur Oztan, Sule Oztan, Neslihan Duzenli, Murat Olukman, Gokhan Koyluoglu
BACKGROUND: Besides stricture formation, diminished esophageal motility after caustic esophageal burns also plays a role in the deterioration of the clinical course. In this study, we aimed to investigate the effect of caustic burn on the esophageal contractions and the effect of platelet-rich plasma (PRP) on these changes. METHODS: Twenty-one Wistar albino rats were divided into three groups [Sham operation (n = 8), caustic esophageal burn with NaOH (n = 6), PRP treatment after caustic burn (n = 7)]...
July 2018: Esophagus: Official Journal of the Japan Esophageal Society
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