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https://www.readbyqxmd.com/read/30114713/acute-effect-of-mitral-valve-repair-on-mitral-valve-geometry
#1
Thilo Noack, Kathleen Wittgen, Philipp Kiefer, Fabian Emrich, Matthias Raschpichler, Sarah Eibel, David Holzhey, Martin Misfeld, Friedrich-Wilhelm Mohr, Michael Borger, Joerg Ender, Joerg Seeburger
BACKGROUND:  The aim of this study was to quantify acute mitral valve (MV) geometry dynamic changes throughout the cardiac cycle using three-dimensional transesophageal echocardiography (3D TEE) in patients undergoing surgical MV repair (MVR) with ring annuloplasty and optional neochord implantation. METHODS:  Twenty-nine patients (63 ± 10 years) with severe primary mitral regurgitation underwent surgical MVR using ring annuloplasty with or without neochord implantation...
August 16, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/30114651/micro-tomographic-analyses-of-specific-interfacial-area-inside-unconsolidated-porous-media-with-differing-particle-characteristics-from-microscopic-to-macroscopic-scale
#2
Anindityo Patmonoaji, Kento Tsuji, Mushlih Muharrik, Tetsuya Suekane
HYPOTHESIS: In capillary trapping in an unconsolidated porous medium, the interphase area is influenced by the distribution of the trapped phase clusters. These attributes, in turn, are affected by particle characteristics, indicating that the interphase area is affected by the particle characteristics. EXPERIMENTS: A micro-tomography technique was used to observe capillary trapping of a nitrogen-water system. The effect of particle characteristics on micro- to macroscopic properties was measured, respectively: pore size distribution (PSD) and porosity, bubble size distribution (BSD) and saturation, and bubble surface area and specific interfacial area...
August 10, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/30114508/post-stroke-losartan-and-captopril-treatments-arrest-hemorrhagic-expansion-in-shrsp-without-lowering-blood-pressure
#3
John S Smeda, Danielle Watson, Jennifer Stuckless, Amit Neghandi
We assessed the ability of poststroke losartan and captopril treatment to attenuate hematoma expansion and plasma extravasation after intracerebral hemorrhagic stroke in Kyoto-Wistar stroke-prone hypertensive rats (SHRsp). Cerebrum volume, herniation and surface areas exhibiting new and old hemorrhages and albumin extravasation were measured prior to and after stroke and following 30 and 60 days of post-stroke losartan or captopril treatment in Evans Blue dye perfused brains. Lesion morphology was studied in serial sections...
August 13, 2018: Vascular Pharmacology
https://www.readbyqxmd.com/read/30114229/determinants-of-bone-damage-an-ex-vivo-study-on-porcine-vertebrae
#4
Mohammad J Mirzaali, Flavia Libonati, Davide Ferrario, Luca Rinaudo, Carmelo Messina, Fabio M Ulivieri, Bruno M Cesana, Matteo Strano, Laura Vergani
Bone's resistance to fracture depends on several factors, such as bone mass, microarchitecture, and tissue material properties. The clinical assessment of bone strength is generally performed by Dual-X Ray Photon Absorptiometry (DXA), measuring bone mineral density (BMD) and trabecular bone score (TBS). Although it is considered the major predictor of bone strength, BMD only accounts for about 70% of fragility fractures, while the remaining 30% could be described by bone "quality" impairment parameters, mainly related to tissue microarchitecture...
2018: PloS One
https://www.readbyqxmd.com/read/30113608/evaluation-of-health-or-pathology-of-bilateral-maxillary-sinuses-in-patients-referred-for-cone-beam-computed-tomography-using-a-low-dose-protocol
#5
Michael M Bornstein, Andy Wai Kan Yeung, Ray Tanaka, Thomas von Arx, Reinhilde Jacobs, Pek-Lan Khong
The aim of this study was to evaluate the health or pathology of bilateral maxillary sinuses using cone beam computed tomography (CBCT) with a low-dose protocol, and to analyze potential influencing factors. The study included only CBCT scans with complete visualization of bilateral maxillary sinuses. The scans were taken using a medium to large field of view and a low-dose protocol, as indicated by the manufacturer. CBCT images were analyzed with regard to the morphology of the sinus membrane and surrounding bone twice by one observer...
September 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/30113573/-the-electrically-evoked-potentials-of-the-auditory-cortex
#6
G A Tavartkiladze
The problems concerning the registration of late latency auditory responses to electric stimulation in the patients wearing cochlear implants are considered. The renewed interest to this class of evoked potentials is due to unexplained differences in the results of cochlear implantation in the patients with the similar audiological data, etiology, age and the history of deafness as well as cochlear implant surgery in children of first years of life and the extended possibilities for speech processor programming...
2018: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/30113523/augmented-anabolic-responses-following-8-weeks-cycling-with-blood-flow-restriction
#7
Miguel S Conceição, Edson M M Junior, Guilherme D Telles, Cleiton A Libardi, Alex Castro, André L L Andrade, Patrícia C Brum, Úrsula Urias, Mirian Ayumi Kurauti, José Maria Costa Júnior, Antonio Carlos Boschero, Cláudia R Cavaglieri, Donny M Camera, Mara P T Chacon-Mikahil
INTRODUCTION: Low-intensity endurance training performed with blood flow restriction (ET-BFR) can improve muscle strength, cross-sectional area (CSA) and cardiorespiratory capacity. Whether muscle strength and CSA as well as cardiorespiratory capacity (i.e.:V˙O2max) and underlying molecular processes regulating such respective muscle adaptations are comparable to resistance and endurance training is unknown. PURPOSE: To determine the respective chronic (i.e.: 8 weeks) functional, morphological and molecular responses of ET-BFR training compared to conventional, unrestricted resistance training (RT) and endurance training (ET)...
August 15, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/30113329/noninvasive-measures-in-atopic-dermatitis
#8
Joachim W Fluhr, Torsten Zuberbier, Razvigor Darlenski
PURPOSE OF REVIEW: To summarize the current knowledge on the morphology, functionality and biochemical composition of the skin in allergic reactions. We address novel noninvasive techniques that promise to disclose intimate mechanisms of skin allergy in vivo. Epidermal barrier is not just a static wrap of the organism but rather a dynamic field for immunological, biophysical and biochemical processes and serves as a bio-sensor for exogenous danger signals. RECENT FINDINGS: Classical biophysical methods are amended by novel in-vivo techniques, such as Raman spectroscopy, analysing the skin microcomposition and develop epidermal profiles...
August 14, 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/30112684/development-growth-and-biomass-simulations-of-two-common-wetland-tree-species-in-texas
#9
Su Min Kim, Jaehak Jeong, Dan Keesee, James R Kiniry
Monitoring the health and condition of wetlands using biological assessments can serve as an effective tool for environmental managers to better evaluate and monitor the status and trends of their wetland ecosystems. Woody species can be used as conspicuous biological assessment tools due to their direct response to environmental change, such as hydrologic alteration. The purpose of this study is to use field-measured morphological measurement indices to develop and optimize tree growth parameters and growth curves using multi-model combination approach to improve tree biomass estimations...
August 15, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/30112501/effects-of-the-vertical-malocclusion-types-on-the-dimension-of-the-mandibular-condyle
#10
Merve Göymen, Ayşegül Güleç
Objective: This study aimed to find the relationship between mandibular condyle morphology and dental malocclusion in patients with anterior open bite, deep bite, and normal overbite. Methods: Eighty patients were included in this retrospective study. All patients had skeletal Class II pattern. The initial panoramic radiographs of patients were digitized using a software program, and groups were compared in terms of condylar height, width, area, and perimeter. In addition, changes in the condyle surface shape were detected using the same panoramic radiographs...
December 2017: Turk J Orthod
https://www.readbyqxmd.com/read/30111557/corticosterone-implants-make-stress-hyporesponsive-birds
#11
Fernando Torres-Medina, Sonia Cabezas, Tracy A Marchant, Martin Wikelski, L Michael Romero, Michaela Hau, Martina Carrete, José L Tella, Julio Blas
In birds, the use of corticosterone (Cort) implants is a frequent tool aimed at simulating systemic elevations of this hormone and studying effects on biological traits (e.g. physiology, morphology, behavior). This manipulation may alter adrenocortical function, potentially changing both baseline (BAS-Cort) and stress-induced (STRESS-Cort) plasma Cort levels. However, implant effects on the latter trait are rarely measured, disregarding downstream consequences of potentially altered stress responses. Here we analyzed the effects of Cort implants on both BAS-Cort and STRESS-Cort in nestling and adult European white storks Ciconia ciconia In addition, we performed a review of 50 studies using Cort implants in birds during the last two decades to contextualize stork results, assess researchers' patterns of use and infer current study biases...
August 15, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/30111405/-autophagy-and-expression-of-uch-l3-induced-by-rapamycin-in-hl-60-cells
#12
Dan Zhao, Hong Yuan
OBJECTIVE: The aim of this study was to explore whether rapamycin can induce the autophagy of HL-60 cells and UCH-L3 expression. METHODS: Cell proliferation activity of HL-60 cells treated with rapamycin was measured by CCK-8 assay. After the cells were treated with rapamycin for different time, the fluorescent microscopy was used to detect the cells' modality, the morphology of autophagosomes was observed by transmission electron microscopy, the mRNA levels of autophagy-related genes LC3-II and UCH-L3 were detected by real-time PCR, and the Western blot was employed to detect the expression level of UCH-L3...
August 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/30111393/-effect-of-daunorubicin-on-release-and-procoagulant-activity-of-microparticles-derived-from-acute-promyelocytic-leukemia-cells
#13
Hai-Tao Li, Shu-Yan Zhao, Zhi-Yu Liu, Jin-Xiao Hou, Ying-Mei Zhang, Dong-Guang Yang, Ping Wang
OBJECTIVE: To investigate the effect of daunorubicin on the number and procoagulant activity of Microparticles derived from acute promyelocytic leukemia(APL) cells. METHODS: APL cells were isolated from bone Marrow of 5 newly diagnosed APL patients, the bone marrow mononuclear cells were collected from 5 patients with iron deficiency anemia as control.APL cells were treated with different concentration of daunorubicin(0.1,0.5,1.0 and 2.0µmol/L) for 24 h. Microparticles were extracted from the cell culture medium for qualitative anaysis of the extracted microparticles...
August 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/30111048/-morphological-microscopic-multiple-component-assay-and-fingerprinting-based-systematic-research-on-quality-evaluation-of-moutan-cortex-paeonia-suffruticosa
#14
Zhi-Qiang Wang, Yong Chen, Shuang-Shuang Liu, Hong-Xiang Li, Wei-Wen Li, Ling Dong, Chun-Nian He, Fei-Hu Chen, Pei-Gen Xiao
The purpose of this study was to combine morphological, microscopic, UHPLC multiple-component assay and fingerprinting studies in order to evaluate the quality of Moutan Cortex (MC) systematically. The root system of Paeonia suffruticosa was measured to compare the morphological variation and the chemical composition of different grades of MC was discussed according to previous studies. The difference between the main microscopic features of MC powder and the xylem powder is dramatic, the MC powder contains great amount of starch granules and clusters of calcium oxalate, while the xylem powder displays considerable vessels...
July 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/30111031/-mechanism-of-nephrotoxicity-of-rhubarb-in-rats
#15
Nuo Deng, Yan Yi, Ai-Hua Liang, Chun-Ying Li, Yong Zhao, Chen Pan, Yu-Shi Zhang, Lian-Mei Wang, Jia-Yin Han, Su-Yan Liu, Jing-Zhuo Tian, Gui-Qin Li, Jing Liu
The aim of this study was to investigate the renal toxicity of rhubarb and its mechanism. The SD rats were randomly divided into three groups: normal group and two rhubarb extract groups (16, 2 g·kg⁻¹). According to the dose conversion method between human and animal, rhubarb 16 g·kg⁻¹ and 2 g·kg⁻¹ were equivalent to 10 times and 1.25 times of human clinical dose respectively. Rhubarb extract was administered by a gastric gavage to rats once daily for 30 days. Serum urea nitrogen (BUN), creatinine (CRE) and urine KIM-1, NGAL and renal morphology were analyzed...
July 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/30110986/development-of-mose%C3%A2-nano-urchins-as-a-sensing-platform-for-a-selective-bio-capturing-of-escherichia-coli-shiga-toxin-dna
#16
Jagriti Narang, Annu Mishra, Roberto Pilloton, Alekhya Vv, Shikha Wadhwa, Chandra Shekhar Pundir, Manika Khanuja
The present study was aimed to develop "fluorine doped" tin oxide glass electrode with a MoSe2 nano-urchin based electrochemical biosensor for detection of Escherichia. coli Shiga toxin DNA. The study comprises two conductive electrodes, and the working electrodes were drop deposited using MoSe2 nano-urchin, and DNA sequences specific to Shiga toxin Escherichia. coli. Morphological characterizations were performed using Fourier transforms infrared spectrophotometer; X-ray diffraction technique and scanning electron microscopy...
August 14, 2018: Biosensors
https://www.readbyqxmd.com/read/30110837/growth-and-shape-of-a-laboratory-alluvial-fan
#17
P Delorme, O Devauchelle, L Barrier, F Métivier
Using laboratory experiments, we investigate the influence of water and sediment discharges on the morphology of an alluvial fan. In our flume, a single-thread laminar river deposits corundum sand into a conical fan. We record the fan progradation with top-view images and measure its shape using the deformation of a Moiré pattern. The fan remains virtually self-affine as it grows, with a nearly constant slope. We find that, when the sediment discharge is small, the longitudinal slope of the fan remains close to that of a river at the threshold for sediment transport...
July 2018: Physical Review. E
https://www.readbyqxmd.com/read/30110004/-three-dimensional-morphological-features-of-temporomandibular-joint-in-skeletal-malocclusion-class-iii-patients-with-different-vertical-skeletal-facial-types
#18
Jie Chen, Yufeng Duan, Jingqiu Tu, Yunyi Yuan, Yonghua Lei
To investigate three-dimensional morphological features of temporomandibular joint in skeletal malocclusion Class III with different vertical skeletal facial types.
 Methods: A total of 46 adults with skeletal malocclusion Class III were enrolled and allocated into a normal-angle, a high-angle and a low-angle groups. All patients were undergone cone beam computed tomography (CBCT). Images of temporomandibular joint were reconstructed and analyzed by Invivo 5. Nine measurements relevant to the positions and forms of condyle as well as joint spaces were performed...
June 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/30109597/striato-nigro-striatal-tract-dispersion-abnormalities-in-patients-with-chronic-schizophrenia
#19
Ana María Rivas-Grajales, Peter Savadjiev, Marek Kubicki, Paul G Nestor, Margaret Niznikiewicz, Robert W McCarley, Carl-Fredrik Westin, Martha E Shenton, James J Levitt
The white matter connections between the midbrain dopamine neurons and the striatum are part of a neural system involved in reward-based learning, a process that is impaired in patients with schizophrenia. The striato-nigro-striatal (SNS) tract, which participates in this process, has not as yet been explored. The present study aimed to use diffusion MRI (dMRI) to delineate the SNS tract, and to compare the application of two dMRI measures, Tract Dispersion (TD), an index of white matter morphology, and Fractional Anisotropy (FA), an index of white matter integrity, to detect group differences between patients with chronic schizophrenia (CSZ) and healthy controls (HC)...
August 14, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/30109470/the-5-ht4-receptor-agonist-prucalopride-stimulates-mucosal-growth-and-enhances-carbohydrate-absorption-in-the-ileum-of-the-mouse
#20
Christine J Park, Sarah J Armenia, Lucy Zhang, Robert A Cowles
BACKGROUND: Enteric serotonin may function as a mucosal growth factor. Previous work demonstrated increased crypt cell proliferation and intestinal mucosal surface area with potentiation of serotonin. While an indirect mechanism was postulated to explain these effects, the presence of 5-HT4 receptors on enterocytes raises the possibility of a direct action of serotonin. We hypothesized that a 5-HT4 specific agonist, prucalopride, would stimulate intestinal mucosal growth and enhance absorptive function in the murine small intestine...
August 14, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
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