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Functional pain

Shirdhya Joypaul, Fiona S Kelly, Michelle A King
Objective: To measure the impact of the multidisciplinary Turning Pain Into Gain program in people experiencing chronic pain of any etiology. Methods: A mixed-methods observational study of 252 participants was used to explore the impact of Turning Pain Into Gain on medication use; quality of life and functioning, as measured by the Pain Self-Efficacy Questionnaire; and self-reported hospitalizations between 2015 and 2016. Results: Responses from 178 participants showed an increased alignment with Australian pain medication guidelines (e...
December 12, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Graham Seow-Hng Goh, Ming Han Lincoln Liow, William Yeo, Zhixing Marcus Ling, Guo Chang Ming, Wai Mun Yue, Seang Beng Tan, Li Tat John Chen
STUDY DESIGN: Retrospective study using prospectively collected registry data. OBJECTIVES: The authors examine the influence of preoperative mental health on outcomes after anterior cervical discectomy and fusion (ACDF) and determine the impact of ACDF on postoperative mental health. SUMMARY OF BACKGROUND DATA: While studies have reported a negative correlation between preoperative mental health and outcomes following lumbar spine surgery, the influence on outcomes following cervical spine surgery remains relatively understudied...
December 11, 2018: Spine
Amy Witkoski Stimpfel, Mattia J Gilmartin
BACKGROUND: Registered nurses are often underprepared with the knowledge and skills to care for hospitalized older adult patients. One strategy to bridge this gap is for hospitals to adopt the Nurses Improving Care for Healthsystem Elders (NICHE) program: A nurse-led interdisciplinary organizational intervention to improve care of hospitalized older adults. OBJECTIVES: This study aimed to identify the market, organizational and managerial, and sociotechnical factors associated with the adoption of NICHE among U...
January 2019: Nursing Research
Michael T Busch, Crystal A Perkins, Brian T Nickel, Daniel J Blizzard, Samuel Clifton Willimon
INTRODUCTION: The insertion of 2 elastic stable intramedullary nails (ESINs) is a common treatment for pediatric femur fractures. However, the use of this technique in length-unstable or metadiaphyseal fractures has historically been associated with higher complication rates. To improve stability, the addition of a third ESIN has been assessed biomechanically and clinically, but the addition of a fourth nail has only been evaluated biomechanically. The purpose of this study is to report our surgical technique and radiographic outcomes using a quartet of ESINs in pediatric femur fractures...
January 2019: Journal of Pediatric Orthopedics
Jeungchan Lee, Ishtiaq Mawla, Jieun Kim, Marco L Loggia, Ana Ortiz, Changjin Jung, Suk-Tak Chan, Jessica Gerber, Vincent J Schmithorst, Robert R Edwards, Ajay D Wasan, Chantal Berna, Jian Kong, Ted J Kaptchuk, Randy L Gollub, Bruce R Rosen, Vitaly Napadow
Although self-report pain ratings are the gold standard in clinical pain assessment, they are inherently subjective in nature and significantly influenced by multidimensional contextual variables. Although objective biomarkers for pain could substantially aid pain diagnosis and development of novel therapies, reliable markers for clinical pain have been elusive. In this study, individualized physical maneuvers were used to exacerbate clinical pain in patients with chronic low back pain (N = 53), thereby experimentally producing lower and higher pain states...
October 17, 2018: Pain
Antonio Matos Rocha, Maurício Mendes de Albuquerque, Eduardo Miguel Schmidt, Cristiano Denoni Freitas, João Paulo Farias, Fernanda Bedin
BACKGROUND: Deep infiltrating colorectal endometriosis may severely affect the quality of life and fertility of patients. Although segmental resection is a therapeutic option that provides positive outcomes in the management of symptoms, its functional effects are still unproven. AIM: Assess the late impact of the laparoscopic approach in treating deep infiltrating endometriosis with segmental colorectal resection. METHODS: Prospective case series of 46 patients submitted to laparoscopic treatment of deep infiltrating endometriosis with segmental colorectal resection between 2013 and 2016...
December 6, 2018: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
David S Tulsky, Pamela A Kisala, Aaron J Boulton, Alan M Jette, David Thissen, Pengsheng Ni, Darren A DeWalt, I-Chan Huang, Yang Liu, M J Mulcahey, Mary Slavin, Brooke Magnus, Holly Crump, Robin Hanks, Susan Charlifue, Bryce B Reeve
PURPOSE: Having independent versions of the PROMIS® scales (for Pediatric and Adults) is problematic as scores cannot be evaluated longitudinally as individuals move from childhood into adulthood. The primary aim of this research project is to use item response theory (IRT) to develop a transitional scoring link (or "crosswalk") between the PROMIS adult and pediatric physical health measures. SETTING: Sample 1 was collected at 6 rehabilitation hospitals in the U...
December 11, 2018: Quality of Life Research
Nina Kampka, Nicole Frommann, Uwe Henning, Robert Schwark, Wolfgang Wölwer, Reinhard Pietrowsky, Christian Luckhaus
The neuropeptide oxytocin (OT) is known to be an important modulator of social cognition. It has been shown that lower OT plasma concentrations are linked to impairments in social cognition. Studies have also shown that intranasal OT may enhance social-cognitive abilities in healthy subjects. We hypothesize that, besides baseline OT concentrations, the reactivity of the OT system may have an important role in social-cognitive functioning of individuals. In the present study, we explored if an emotional challenge paradigm is suitable to elicit OT release into plasma to make the reactivity of the OT system measurable...
December 11, 2018: Journal of Neural Transmission
Fuzhen Yuan, Zewen Sun, Haijun Wang, Yourong Chen, Jiakuo Yu
PURPOSE: A cutting guide technique for patella resurfacing in total knee arthroplasty was expected to result in less patellofemoral syndromes. The aim of this study was to identify differences in the patellofemoral function, clinical outcomes, and radiographic parameters between the freehand and cutting guide patellar resection techniques in patients undergoing total knee arthroplasty. METHODS: A prospective randomized controlled trial was conducted. The study was registered in a public trials registry (International Standard Randomized Trial No...
December 11, 2018: International Orthopaedics
Philip P Roessler, Max Jaenisch, Manuel Kuhlmann, Miriam Wacker, P Johannes Wagenhäuser, Sascha Gravius, Dieter C Wirtz
PURPOSE: Acetabular revision of failed total hip arthroplasty (THA) is often associated with severe bone loss. Therefore, a variety of revision implant systems has been developed during recent years, with the augment-and-modular-cage system being one of the newest additions to this portfolio. Together with biologic downsizing by means of impaction bone grafting, this uncemented system promises a high modularity and versatility to treat all acetabular defects up to Paprosky types IIIa and IIIb without pelvic discontinuity...
December 11, 2018: International Orthopaedics
Frank S Fröschen, Nadine Gravius, Jan-Frederic Lau, Thomas Martin Randau, Eva Kaup, Max J Friedrich, Sascha Gravius
PURPOSE: The contact allergens nickel, cobalt, and chromium are often discussed as possible triggers of allergic reactions to orthopedic implants. Additionally, acrylates and polymerization additives in bone cement (e.g., benzoyl peroxide (BPO)) have been implicated as triggers of eczema, wound healing disorders, and aseptic implant loosening. We report about six patients with aseptic loosening after total knee arthroplasty (TKA), who underwent revision surgery after testing positive for BPO hypersensitivity...
December 11, 2018: International Orthopaedics
M Rossi, G Bruno, M Chiusalupi, A Ciaramella
Poor emotional awareness (EA) seems to play an important role in the aetiology of functional somatic complaints featuring pain as a form of somatisation. The aim of this study was to shed more light on this relationship by investigating the links between pain, somatisation, and emotional awareness in a nonclinical population of 445 children aged 6-10. Assessing pain through the Children's Somatisation Inventory (CSI), a very high percentage of the entire sample complained of experiencing pain at least one site (84...
2018: Pain Research and Treatment
Marcos F DosSantos, Aleli T Oliveira, Natália R Ferreira, Antônio C P Carvalho, Paulo Henrique Rosado de Castro
Chronic pain is an important public health issue. Moreover, its adequate management is still considered a major clinical problem, mainly due to its incredible complexity and still poorly understood pathophysiology. Recent scientific evidence coming from neuroimaging research, particularly functional magnetic resonance (fMRI) and positron emission tomography (PET) studies, indicates that chronic pain is associated with structural and functional changes in several brain structures that integrate antinociceptive pathways and endogenous modulatory systems...
2018: Pain Research & Management: the Journal of the Canadian Pain Society
Sung Hae Chang, Yun-Kyung Song, Seong-Su Nah
Background: Gumiganghwal-tang (GMGHT) is a traditional herbal medicine consisting of nine different herbs. GMGHT inhibits the mRNA expression and production of inflammatory cytokines tumor necrosis factor- α (TNF- α ), interleukin-6 (IL-6), and TNF- β on lipopolysaccharide- (LPS-) stimulated peritoneal macrophages in a dose-dependent manner. It is empirically used for the treatment of inflammatory disease, but there are few reports of clinical trials that investigate its efficacy and safety...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Nguyen Truong Giang, Nguyen Van Nam, Nguyen Ngoc Trung, Le Viet Anh, Nguyen Manh Cuong, Ngo Van Dinh, Dinh Cong Pho, Phillip Geiger, Nguyen Trung Kien
Background: Paravertebral block has been proven to be an efficient method to provide post-thoracotomy pain management. This study aimed to compare patient-controlled paravertebral analgesia (PCPA) and intravenous patient-controlled analgesia (IVPCA) in terms of analgesic efficiency, respiratory function, and adverse effects after video-assisted thoracoscopic surgery (VATS) lobectomy. Patients and methods: The prospective randomized trial study was carried out on 60 patients who underwent VATS lobectomy (randomly allocated 30 patients in each group)...
2018: Local and Regional Anesthesia
Nada Lukkahatai, Brian Walitt, Enrique J Deandrés-Galiana, Juan Luis Fernández-Martínez, Leorey N Saligan
Objectives: Fibromyalgia syndrome (FMS) is a chronic and often debilitating condition that is characterized by persistent fatigue, pain, bowel abnormalities, and sleep disturbances. Currently, there are no definitive prognostic or diagnostic biomarkers for FMS. This study attempted to utilize a novel predictive algorithm to identify a group of genes whose differential expression discriminated individuals with FMS diagnosis from healthy controls. Methods: Secondary analysis of gene expression data from 28 women with FMS and 19 age-and race-matched healthy women...
2018: Journal of Pain Research
Pierce D Nunley, Timothy R Deer, Ramsin M Benyamin, Peter S Staats, Jon E Block
Background: Lumbar spinal stenosis (LSS) causes significant pain and functional impairment, and medical management has increasingly included the prescription of opioid-based analgesics. Interspinous process decompression (IPD) provides a minimally-invasive treatment option for LSS. Methods: This study estimated the type, dosage, and duration of opioid medications through 5 years of follow-up after IPD with the Superion Indirect Decompression System (Vertiflex Inc...
2018: Journal of Pain Research
David J DiBenedetto, Kelly M Wawrzyniak, Michael E Schatman, Ronald J Kulich, Matthew Finkelman
Objective: To evaluate clinical outcomes and health care utilization at 12 months post spinal cord stimulator (SCS) implantation compared with baseline and a matched sample of patients receiving conventional medical management (CMM) for the treatment of low back and lower extremity pain. Patients: A retrospective study of patients with at least 24 months of active treatment at an interdisciplinary community pain center between December 1, 2014 and December 31, 2017...
2018: Journal of Pain Research
Surender Dabas, Karan Gupta, Yogendra Singh Bhakuni, Reetesh Ranjan, Himanshu Shukla, Ashwani Sharma
The aim of this observational prospective study was to determine the technical feasibility, safety, and adequacy of robotic hemithyroidectomy. From April 2015 to May 2016, 16 patients with solitary thyroid lesion underwent robotic hemithyroidectomy using the Da Vinci® Si Surgical system. Patients were observed and data were recorded on surgical time, blood loss, complications, and functional outcome of the patients. A total of 16 patients (3 males and 13 females; mean age 39.9 years) underwent robotic hemithyroidectomy after evaluation for solitary thyroid nodule with a mean nodule size of 2...
December 2018: Indian Journal of Surgical Oncology
Emad Khazneh, Alaa Shamlawi, Kamel Jebrin, Zakaria Hamdan, Osama Sawalmeh
BACKGROUND: Baclofen is a centrally acting GABAB receptor agonist and it is used widely for the treatment of spasticity, persistent hiccups and multiple sclerosis. The renal system is the main route of excretion, thus people with suboptimal renal function are prone to baclofen intoxication. Multiple doses of baclofen have been associated with toxicity, but it is very unusual that single dose can do so. CASE PRESENTATION: A 47 year old female patient with end stage renal disease (ESRD) presented with a sudden onset of altered mental status and state of unconsciousness after the ingestion of one tablet of baclofen 25 mg...
December 11, 2018: BMC Nephrology
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