keyword
MENU ▼
Read by QxMD icon Read
search

Ampicillin/sulbactam, prolonged infusion

keyword
https://www.readbyqxmd.com/read/19760927/the-efficacy-of-prophylactic-administration-of-sbt-abpc-for-preventing-surgical-site-infection-in-elderly-patients-undergoing-colorectal-surgery
#1
Soichi Tsutsumi, Satoru Yamaguchi, Kaori Tsuboi, Takaharu Fukasawa, Sayaka Yamaki, Takayuki Asao, Hiroyuki Kuwano
BACKGROUND/AIMS: Colorectal surgery presents a high risk of surgical site infections (SSI). SSI and prolonged hospital stay were associated with being aged 75 yrs or older. The present study investigated the efficacy of sulbactam sodium/ampicillin sodium (SBT/ABPC), which is a combination drug of ampicillin and beta-lactamase inhibitor, as a prophylactic drug against SSI in elderly patient underwent colorectal surgery. METHODOLOGY: From July 2003 to November 2005, a total of 181 patients underwent colorectal surgery...
July 2009: Hepato-gastroenterology
https://www.readbyqxmd.com/read/19621674/the-efficacy-of-prophylactic-administration-of-sbt-abpc-for-preventing-surgical-site-infection-in-elderly-patients-undergoing-colorectal-surgery
#2
Soichi Tsutsumi, Satoru Yamaguchi, Kaori Tsuboi, Takaharu Fukasawa, Sayaka Yamaki, Takayuki Asao, Hiroyuki Kuwano
BACKGROUND/AIMS: Colorectal surgery presents a high risk of surgical site infections (SSI). SSI and prolonged hospital stay were associated with being aged 75 years or older. We investigated the efficacy of sulbactam sodium/ampicillin sodium (SBT/ABPC), which is a combination drug of ampicillin and beta-lactamase inhibitor, as a prophylactic drug against SSI in elderly patients undergoing colorectal surgery. METHODOLOGY: From July 2003 to November 2005, a total of 181 patients underwent colorectal surgery...
May 2009: Hepato-gastroenterology
https://www.readbyqxmd.com/read/16258323/treatment-of-multidrug-resistant-acinetobacter
#3
REVIEW
Clinton K Murray, Duane R Hospenthal
PURPOSE OF REVIEW: Acinetobacter baumannii-calcoaceticus complex has become a serious nosocomial pathogen due to its persistence in the hospital environment and its broad antimicrobial resistance patterns. This review summarizes the most recent literature pertaining to the clinical management of infections with this bacteria emphasizing in-vitro antimicrobial resistance patterns and antimicrobial efficacy in animals and humans. RECENT FINDINGS: Although this pathogen can be associated with an elevated crude mortality, it only contributes to this mortality in a subset of high-risk patients...
December 2005: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/12824971/antibiotic-therapy-in-preterm-premature-rupture-of-membranes-are-seven-days-necessary-a-preliminary-randomized-clinical-trial
#4
RANDOMIZED CONTROLLED TRIAL
David F Lewis, C David Adair, Alfred G Robichaux, Ronald K Jaekle, Jodi A Moore, Arthur T Evans, M Todd Fontenot
OBJECTIVE: The purpose of this study was to determine whether 3 days of broad-spectrum antibiotic therapy, which is intended to prolong latency in patients with preterm premature rupture of membranes, is comparable to 7 days of therapy. STUDY DESIGN: Patients with preterm premature rupture of membranes at three separate study sites were asked to participate in this intent-to-treat, prospective, randomized trial. They were assigned randomly to either 3 or 7 days of ampicillin-sulbactam (3 g intravenously every 6 hours)...
June 2003: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/8840374/qtc-interval-prolongation-associated-with-slow-intravenous-erythromycin-lactobionate-infusions-in-critically-ill-patients-a-prospective-evaluation-and-review-of-the-literature
#5
REVIEW
S J Tschida, D R Guay, R J Straka, L L Hoey, R Johanning, K Vance-Bryan
Intravenous erythromycin has recently been associated with significant QTc interval prolongation, torsades de pointes, and sudden cardiac death. The prolonged the QTc interval attributed to erythromycin typically is associated with rapid infusion rates in excess of 10 mg/minute. We prospectively assessed the relationship between QTc interval prolongation and erythromycin administration by slow intravenous infusion (mean rate 8.9 +/- 3.5 mg/minute, range 3.9-16.7 mg/minute). Electrocardiographic (ECG) rhythm strips were prospectively obtained in 44 critically ill patients receiving intravenous antibiotics (22 received erythromycin and 22 ceftazidime, cefuroxime, cefotaxime, ceftriaxone, or ampicillin-sulbactam as controls)...
July 1996: Pharmacotherapy
https://www.readbyqxmd.com/read/1759832/pharmacokinetics-of-ampicillin-sulbactam-in-healthy-elderly-and-young-volunteers
#6
COMPARATIVE STUDY
B R Meyers, P Wilkinson, M H Mendelson, S Walsh, C Bournazos, S Z Hirschman
The pharmacokinetics of ampicillin-sulbactam in elderly subjects (65 to 85 years; group 3, n = 8), compared with those in middle-aged (41 to 64 years; group 2, n = 8) and younger (20 to 40 years; group 1, n = 8) subjects, were investigated. A single 2-g dose of ampicillin combined with 1 g of sulbactam in 60 ml of intravenous solution was administered to each subject over a 30-min period. Blood and urine samples were taken at baseline and serially over an 8.5-h period following the infusion. Ampicillin and sulbactam concentrations were assayed by high-performance liquid chromatography on a reversed-phase C-8 column...
October 1991: Antimicrobial Agents and Chemotherapy
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"