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https://www.readbyqxmd.com/read/27925212/sucrose-replacement-in-high-ratio-white-layer-cakes
#1
Rebecca A Miller, Orelia E Dann, Amanda R Oakley, Megan E Angermayer, Katherine H Brackebusch
BACKGROUND: Several commercially available alternative sweeteners have potential in reducing the caloric content of baked products. Sugar alcohols and natural sweeteners have similar bulk as sucrose and can replace sucrose directly. High intensity sweeteners have high potency but light weight so bulking agents are often added. This study determined alternative sweeteners and combinations of alternative sweetener and a bulking agent that produced good quality white layer cakes. RESULTS: Cakes made with maltitol were acceptable but erythritol and fructose produced undesirable cakes...
December 7, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27909849/monitoring-contaminants-of-emerging-concern-from-tertiary-wastewater-treatment-plants-using-passive-sampling-modelled-with-performance-reference-compounds
#2
Tamanna Sultana, Craig Murray, M Ehsanul Hoque, Chris D Metcalfe
The Lake Simcoe watershed in Ontario, Canada is an important recreational area and a recharge zone for groundwater resources. Lake Simcoe is a relatively shallow lotic system that has been impacted by urban development, recreation, industry and agriculture. As part of a watershed management plan, six wastewater treatment plants (WWTPs) located in this catchment basin were selected to measure the inputs of contaminants of emerging concern (CECs) of wastewater origin. These WWTPs were recently upgraded to tertiary treatment for phosphorus removal...
December 2016: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27896590/improvement-in-thermal-stability-of-sucralose-by-%C3%AE-cyclodextrin-metal-organic-frameworks
#3
Nana Lv, Tao Guo, Botao Liu, Caifen Wang, Vikaramjeet Singh, Xiaonan Xu, Xue Li, Dawei Chen, Ruxandra Gref, Jiwen Zhang
PURPOSE: To explain thermal stability enhancement of an organic compound, sucralose, with cyclodextrin based metal organic frameworks. METHODS: Micron and nanometer sized basic CD-MOFs were successfully synthesized by a modified vapor diffusion method and further neutralized with glacial acetic acid. Sucralose was loaded into CD-MOFs by incubating CD-MOFs with sucralose ethanol solutions. Thermal stabilities of sucralose-loaded basic CD-MOFs and neutralized CD-MOFs were investigated using thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and high performance liquid chromatography with evaporative light-scattering detection (HPLC-ELSD)...
November 28, 2016: Pharmaceutical Research
https://www.readbyqxmd.com/read/27877104/sweet-taste-receptor-serves-to-activate-glucose-and-leptin-responsive-neurons-in-the-hypothalamic-arcuate-nucleus-and-participates-in-glucose-responsiveness
#4
Daisuke Kohno, Miho Koike, Yuzo Ninomiya, Itaru Kojima, Tadahiro Kitamura, Toshihiko Yada
The hypothalamic feeding center plays an important role in energy homeostasis. In the feeding center, whole-body energy signals including hormones and nutrients are sensed, processed, and integrated. As a result, food intake and energy expenditure are regulated. Two types of glucose-sensing neurons exist in the hypothalamic arcuate nucleus (ARC): glucose-excited neurons and glucose-inhibited neurons. While some molecules are known to be related to glucose sensing in the hypothalamus, the mechanisms underlying glucose sensing in the hypothalamus are not fully understood...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27848976/tea-induced-calmness-sugar-sweetened-tea-calms-consumers-exposed-to-acute-stressor
#5
Shilpa S Samant, Katherine Wilkes, Zephania Odek, Han-Seok Seo
The food and beverage industry has been increasingly replacing sugar with non-nutritive sweeteners in their sweetened products to control or reduce total calories. Research comparing the effect of nutritive and non-nutritive sweeteners on emotional state of participants exposed to acute stressors is still limited. This study aimed to determine the effect of drinking tea sweetened with either a nutritive sweetener (sugar) or a non-nutritive sweetener (sucralose or stevia) on emotional state, in terms of calmness and pleasantness, of participants exposed to an acute stressor...
November 16, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27822576/a-database-on-the-stability-of-silver-and-gold-nanostructures-for-applications-in-biology-and-biomolecular-sciences
#6
Hasitha de Alwis Weerasekera, María Jazmín Silvero, Daliane Regis Correa da Silva, Juan C Scaiano
Colloidal stability of nanoparticles in biological media is an important consideration when trying to ensure reliable data interpretation of in vitro and in vivo systems. We have developed a detailed colloidal stability library of newly synthesized gold, silver and gold-core silver-shell plasmonic nanoparticles, stabilized with aspartame, glucosamine and sucralose, in various biologically relevant buffers and bacterial and mammalian cell culture media. The stabilizer selection reflects the preference for molecules that are non-toxic, inexpensive, readily available, water soluble and easy-to-replace if that is the end-user preference...
November 8, 2016: Biomaterials Science
https://www.readbyqxmd.com/read/27800650/supplementation-of-oligofructose-but-not-sucralose-decreases-high-fat-diet-induced-body-weight-gain-in-mice-independent-of-gustducin-mediated-gut-hormone-release
#7
Sandra Steensels, Leen Cools, Bert Avau, Laurien Vancleef, Ricard Farré, Kristin Verbeke, Inge Depoortere
SCOPE: Enteroendocrine cells sense nutrients through taste receptors similar to those on the tongue. Sweet and fatty acid taste receptors (FFAR) coupled to the gustatory G-protein, gustducin, on enteroendocrine cells play a role in gut hormone release. We studied if supplementation of artificial (sucralose) or prebiotic (oligofructose; OFS) sweeteners target gustducin-mediated signaling pathways to alter gut hormone release and reduce obesity-associated disorders. METHODS AND RESULTS: Wild-type (WT) and α-gustducin knockout (α-gust(-/-) ) mice were fed a high-fat diet and gavaged once daily (8 wk) with water or equisweet concentrations of sweeteners...
October 31, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27777606/hormonal-responses-to-non-nutritive-sweeteners-in-water-and-diet-soda
#8
Allison C Sylvetsky, Rebecca J Brown, Jenny E Blau, Mary Walter, Kristina I Rother
BACKGROUND: Non-nutritive sweeteners (NNS), especially in form of diet soda, have been linked to metabolic derangements (e.g. obesity and diabetes) in epidemiologic studies. We aimed to test acute metabolic effects of NNS in isolation (water or seltzer) and in diet sodas. METHODS: We conducted a four-period, cross-over study at the National Institutes of Health Clinical Center (Bethesda, Maryland). Thirty healthy adults consumed 355 mL water with 0 mg, 68 mg, 170 mg, and 250 mg sucralose, and 31 individuals consumed 355 mL caffeine-free Diet Rite Cola™, Diet Mountain Dew™ (18 mg sucralose, 18 mg acesulfame-potassium, 57 mg aspartame), and seltzer water with NNS (68 mg sucralose and 41 mg acesulfame-potassium, equivalent to Diet Rite Cola™) in randomized order, prior to oral glucose tolerance tests...
2016: Nutrition & Metabolism
https://www.readbyqxmd.com/read/27765786/psychophysical-evaluation-of-sweetness-functions-across-multiple-sweeteners
#9
Julia Y Q Low, Robert L McBride, Kathleen E Lacy, Russell S J Keast
Sweetness is one of the 5 prototypical tastes and is activated by sugars and non-nutritive sweeteners (NNS). The aim of this study was to investigate measures of sweet taste function [detection threshold (DT), recognition threshold (RT), and suprathreshold intensity ratings] across multiple sweeteners. Sixty participants, 18-52 years of age (mean age in years = 26, SD = ±7.8), were recruited to participate in the study. DT and RT were collected for caloric sweeteners (glucose, fructose, sucrose, erythritol) and NNS (sucralose, rebaudioside A)...
October 20, 2016: Chemical Senses
https://www.readbyqxmd.com/read/27753624/biological-fate-of-low-calorie-sweeteners
#10
REVIEW
Bernadene A Magnuson, Michael C Carakostas, Nadia H Moore, Sylvia P Poulos, Andrew G Renwick
With continued efforts to find solutions to rising rates of obesity and diabetes, there is increased interest in the potential health benefits of the use of low- and no-calorie sweeteners (LNCSs). Concerns about safety often deter the use of LNCSs as a tool in helping control caloric intake, even though the safety of LNCS use has been affirmed by regulatory agencies worldwide. In many cases, an understanding of the biological fate of the different LNSCs can help health professionals to address safety concerns...
November 2016: Nutrition Reviews
https://www.readbyqxmd.com/read/27744200/toxicological-hazard-induced-by-sucralose-to-environmentally-relevant-concentrations-in-common-carp-cyprinus-carpio
#11
Karinne Saucedo-Vence, Armando Elizalde-Velázquez, Octavio Dublán-García, Marcela Galar-Martínez, Hariz Islas-Flores, Nely SanJuan-Reyes, Sandra García-Medina, María Dolores Hernández-Navarro, Leobardo Manuel Gómez-Oliván
Sucralose (SUC) is an artificial sweetener that is now widely used in North American and Europe; it has been detected in a wide variety of aquatic environments. It is considered safe for human consumption but its effects in the ecosystem have not yet been studied in depth, since limited ecotoxicological data are available in the peer-reviewed literature. This study aimed to evaluate potential SUC-induced toxicological hazard in the blood, brain, gill, liver and muscle of Cyprinus carpio using oxidative stress biomarkers...
October 13, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27742692/lipid-lowering-pharmaceutical-clofibrate-inhibits-human-sweet-taste
#12
Matthew Kochem, Paul A S Breslin
T1R2-T1R3 is a heteromeric receptor that binds sugars, high potency sweeteners, and sweet taste blockers. In rodents, T1R2-T1R3 is largely responsible for transducing sweet taste perception. T1R2-T1R3 is also expressed in non-taste tissues, and a growing body of evidence suggests that it helps regulate glucose and lipid metabolism. It was previously shown that clofibric acid, a blood lipid-lowering drug, binds T1R2-T1R3 and inhibits its activity in vitro The purpose of this study was to determine whether clofibric acid inhibits sweetness perception in humans and is, therefore, a T1R2-T1R3 antagonist in vivo Fourteen participants rated the sweetness intensity of 4 sweeteners (sucrose, sucralose, Na cyclamate, acesulfame K) across a broad range of concentrations...
October 14, 2016: Chemical Senses
https://www.readbyqxmd.com/read/27699780/diet-and-headache-part-1
#13
Vincent T Martin, Brinder Vij
BACKGROUND: The role of diet in the management of the headache patient is a controversial topic in the headache field. OBJECTIVES: To review the evidence supporting the hypothesis that specific foods or ingredients within foods and beverages trigger attacks of headache and/or migraine and to discuss the use of elimination diets in the prevention of headache disorders METHODS: This represents part 1 of a narrative review of the role of diet in the prevention of migraine and other headache disorders...
October 2016: Headache
https://www.readbyqxmd.com/read/27664681/influence-of-hydrogenated-oil-as-cocoa-butter-replacers-in-the-development-of-sugar-free-compound-chocolates-use-of-inulin-as-stabilizing-agent
#14
Laura T Rodriguez Furlán, Yanina Baracco, Javier Lecot, Noemi Zaritzky, Mercedes E Campderrós
The effect of the addition of inulin as a surfactant or stability agent on white compound chocolate sweetened with sucralose and Stevia was studied. Samples were stored at 7, 15 and 30°C during 100days and the influence of inulin on rheological properties, sensorial attributes, shelf-life, physical properties such as melting, crystallization and blooming were analyzed. The shelf-life of the compound chocolate with the incorporation of inulin was higher than the control sample without replacement. Compound chocolate with inulin at 10%w/w showed a dense matrix structure, reducing the size and number of fat crystals formed during storage; furthermore they presented higher values of brightness and WI...
February 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27637500/miracle-fruit-an-alternative-sugar-substitute-in-sour-beverages
#15
Jéssica Ferreira Rodrigues, Rafaela da Silva Andrade, Sabrina Carvalho Bastos, Sandra Bragança Coelho, Ana Carla Marques Pinheiro
High sugar consumption has been related to several chronic diseases and thus, many alternative sweeteners have been extensively researched. However, there is still controversy regarding the harmful effects of their consumption, mainly regarding the use of artificial sweeteners, controversy which increases the demand for natural sweeteners, such as miracle fruit. This tropical plant grows in West Africa is named for its unique ability of changing a sour taste into sweet. Therefore, this study aimed to characterize the temporal profile of miracle fruit and assess its sugar substitute power in sour beverages through time-intensity and temporal dominance of sensations tests...
December 1, 2016: Appetite
https://www.readbyqxmd.com/read/27613866/positive-allosteric-modulation-of-the-calcium-sensing-receptor-by-physiological-concentrations-of-glucose
#16
Johan Medina, Yuko Nakagawa, Masahiro Nagasawa, Anny Fernandez, Kazushige Sakaguchi, Tetsuya Kitaguchi, Itaru Kojima
The calcium-sensing receptor (CaSR) is activated by various cations, cationic compounds, and amino acids. In the present study we investigated the effect of glucose on CaSR in HEK293 cells stably expressing human CaSR (HEK-CaSR cells). When glucose concentration in the buffer was raised from 3 to 25 mm, a rapid elevation of cytoplasmic Ca(2+) concentration ([Ca(2+)]c) was observed. This elevation was immediate and transient and was followed by a sustained decrease in [Ca(2+)]c The effect of glucose was detected at a concentration of 4 mm and reached its maximum at 5 mm 3-O-Methylglucose, a non-metabolizable analogue of glucose, reproduced the effect of glucose...
October 28, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27567550/cross-over-studies-underestimate-energy-compensation-the-example-of-sucrose-versus-sucralose-containing-drinks
#17
Nouf S Gadah, Jeffrey M Brunstrom, Peter J Rogers
The vast majority of preload-test-meal studies that have investigated the effects on energy intake of disguised nutrient or other food/drink ingredient manipulations have used a cross-over design. We argue that this design may underestimate the effect of the manipulation due to carry-over effects. To test this we conducted comparable cross-over (n = 69) and parallel-groups (n = 48) studies testing the effects of sucrose versus low-calorie sweetener (sucralose) in a drink preload on test-meal energy intake...
December 1, 2016: Appetite
https://www.readbyqxmd.com/read/27553043/humans-can-taste-glucose-oligomers-independent-of-the-ht1r2-ht1r3-sweet-taste-receptor
#18
Trina J Lapis, Michael H Penner, Juyun Lim
It is widely accepted that humans can taste mono- and disaccharides as sweet substances, but they cannot taste longer chain oligo- and polysaccharides. From the evolutionary standpoint, the ability to taste starch or its oligomeric hydrolysis products would be highly adaptive, given their nutritional value. Here, we report that humans can taste glucose oligomer preparations (average degree of polymerization 7 and 14) without any other sensorial cues. The same human subjects could not taste the corresponding glucose polymer preparation (average degree of polymerization 44)...
August 23, 2016: Chemical Senses
https://www.readbyqxmd.com/read/27543946/a-national-reconnaissance-of-trace-organic-compounds-tocs-in-united-states-lotic-ecosystems
#19
Melody J Bernot, Jesse C Becker, Jason Doll, Thomas E Lauer
We collaborated with 26 groups from universities across the United States to sample 42 sites for 33 trace organic compounds (TOCs) in water and sediments of lotic ecosystems. Our goals were 1) to further develop a national database of TOC abundance in United States lotic ecosystems that can be a foundation for future research and management, and 2) to identify factors related to compound abundance. Trace organic compounds were found in 93% of water samples and 56% of sediment samples. Dissolved concentrations were 10-1000× higher relative to sediment concentrations...
August 17, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27507005/pubertal-status-pre-meal-drink-composition-and-later-meal-timing-interact-in-determining-children-s-appetite-and-food-intake
#20
Barkha P Patel, Jill K Hamilton, Shirley Vien, Scott G Thomas, G Harvey Anderson
Puberty is a period of development that alters energy intake patterns. However, few studies have examined appetite and food intake (FI) regulation during development of puberty in children and adolescents. Therefore, the objective was to measure the effect of pubertal status on FI and subjective appetite after pre-meal glucose and whey protein drinks in 9- to 14-year-old boys and girls. In a within-subject, randomized, repeated-measures design, children (21 pre-early pubertal, 15 mid-late pubertal) received equally sweetened drinks containing Sucralose (control), glucose, or whey protein (0...
September 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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