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https://www.readbyqxmd.com/read/30544571/10-hda-a-major-fatty-acid-of-royal-jelly-exhibits-ph-dependent-growth-inhibitory-activity-against-different-strains-of-paenibacillus-larvae
#1
Mária Šedivá, Maroš Laho, Lenka Kohútová, Andrea Mojžišová, Juraj Majtán, Jaroslav Klaudiny
Paenibacillus larvae ( P. larvae ) is a bacterial pathogen causing American foulbrood (AFB), the most serious disease of honeybee larvae. The food of young larvae could play an important role in the resistance of larvae against AFB. It contains antibacterial substances produced by honeybees that may inhibit the propagation of the pathogen in larval midguts. In this study, we identified and investigated the antibacterial effects of one of these substances, trans -10-hydroxy-2-decenoic acid (10-HDA), against P...
December 7, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/30537781/-use-of-negative-pressure-wound-therapy-with-instillation-and-dwell-time-for-wound-treatment-results-of-an-expert-consensus-conference
#2
Raymund E Horch, Chris Braumann, Joachim Dissemond, Burkhard Lehner, Christoph Hirche, Guido Woeste, Gernot Wozniak, Walter Wetzel-Roth, Christian Willy
Rinsing wounds with wound cleansing solutions has long been a recognised cornerstone in wound management as a means of removing cell debris and surface pathogens in wound exudates. In combination with surgical debridement and topical negative pressure wound therapy (NPWT), this can facilitate the intended progression from the inflammatory to the proliferative phase of wound healing. Procedures of topical negative pressure wound therapy with instillation and a defined exposure/dwell-time of topical solutions under cyclic compression and decompression with foam dressings (NPWTi-d) can remove cellular remnants and debris that may inhibit the healing process...
December 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/30537318/nomenklatur-der-kutanen-vaskulitiden-deutschsprachige-definitionen-des-dermatologischen-anhanges-zur-chapel-hill-consensus-conference
#3
REVIEW
Cord Sunderkötter, Peter Lamprecht, Alfred Mahr, Dieter Metze, Bernhard Zelger
No abstract text is available yet for this article.
December 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/30537317/nomenclature-of-cutaneous-vasculitides-german-translation-of-the-dermatologic-addendum-to-the-2012-revised-international-chapel-hill-consensus-conference-nomenclature-of-vasculitides
#4
REVIEW
Cord Sunderkötter, Peter Lamprecht, Alfred Mahr, Dieter Metze, Bernhard Zelger
The nomenclature system agreed upon by the Chapel Hill Consensus Conference (CHCC) with respect to the terminology and precise definition of the various types of vasculitis has gained widespread interdisciplinary and international acceptance. As the revised version from 2012 (CHCC 2012) does not address the special features of vasculitis of the skin, it has recently been supplemented with an addendum containing the nomenclature of cutaneous vasculitides (D-CHCC). The present article provides the German translation of the terms and defintions of the D-CHCC as well as additional explanatory comments...
December 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/30527996/pulmonary-hypertension-associated-with-left-heart-disease-updated-recommendations-of-the-cologne-consensus-conference-2018
#5
Stephan Rosenkranz, Irene M Lang, Rüdiger Blindt, Diana Bonderman, Leonhard Bruch, Gerhard P Diller, Ralf Felgendreher, Christian Gerges, Wolfgang Hohenforst-Schmidt, Stephan Holt, Christian Jung, Ingrid Kindermann, Tilmann Kramer, Wolfgang M Kübler, Veselin Mitrovic, Andreas Riedel, Andreas Rieth, Alexander Schmeisser, Rolf Wachter, Joachim Weil, Christian F Opitz
In the summer of 2016, delegates from the German Society of Cardiology (DGK), the German Respiratory Society (DGP), and the German Society of Pediatric Cardiology (DGPK) met in Cologne, Germany, to define consensus-based practice recommendations for the management of patients with pulmonary hypertension (PH). These recommendations were built on the 2015 European Pulmonary Hypertension guidelines, aiming at their practical implementation, considering country-specific issues, and including new evidence, where available...
August 27, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/30526896/introduction-epidemiology-and-classification-of-vasculitis
#6
REVIEW
Richard A Watts, Joanna Robson
Classification of the vasculitides has been traditionally based on vessel size. The American College of Rheumatology (ACR) criteria were developed in the 1980s and published in 1990 before the development of ANCA testing and modern imaging techniques such as MRI and PET scanning, and therefore, these criteria are not fit for use in 2010s. The Chapel Hill Consensus Conference provided a framework for defining various types of vasculitis. In the next two years, new classification criteria will be published from the DCVAS study, which will provide a modern system for the classification of vasculitis for clinical studies...
February 2018: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/30526419/extended-antibiotic-course-prior-to-interval-appendectomy-in-children-with-complicated-appendicitis-offers-no-significant-advantage
#7
Faidah Badru, Nicholas Piening, Jose Greenspon, Kaveer Chatoorgoon, Colleen Fitzpatrick, Gustavo A Villalona
BACKGROUND: No consensus exists regarding duration of antibiotic therapy for complicated appendicitis treated with interval appendectomy. We hypothesized that more than two weeks of antibiotic therapy does not decrease complication rates in asymptomatic patients. PATIENTS AND METHODS: A retrospective review of all patients with complicated appendicitis treated with interval appendectomy from 2010-2015 was performed. We divided the patients in two groups (group 1, ≤2 weeks of antibiotics; group 2: >2 weeks of antibiotics)...
December 11, 2018: Surgical Infections
https://www.readbyqxmd.com/read/30516605/multimodality-monitoring-in-the-neurocritical-care-unit
#8
Lucia Rivera Lara, Hans Adrian Püttgen
PURPOSE OF REVIEW: This article focuses on the multiple neuromonitoring devices that can be used to collect bedside data in the neurocritical care unit and the methodology to integrate them into a multimodality monitoring system. The article describes how to apply the collected data to appreciate the physiologic changes and develop therapeutic approaches to prevent secondary injury. RECENT FINDINGS: The neurologic examination has served as the primary monitor for secondary brain injury in patients admitted to the neurocritical care unit...
December 2018: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/30515610/the-use-of-3d-laparoscopic-imaging-systems-in-surgery-eaes-consensus-development-conference-2018
#9
Alberto Arezzo, Nereo Vettoretto, Nader K Francis, Marco Augusto Bonino, Nathan J Curtis, Daniele Amparore, Simone Arolfo, Manuel Barberio, Luigi Boni, Ronit Brodie, Nicole Bouvy, Elisa Cassinotti, Thomas Carus, Enrico Checcucci, Petra Custers, Michele Diana, Marilou Jansen, Joris Jaspers, Gadi Marom, Kota Momose, Beat P Müller-Stich, Kyokazu Nakajima, Felix Nickel, Silvana Perretta, Francesco Porpiglia, Francisco Sánchez-Margallo, Juan A Sánchez-Margallo, Marlies Schijven, Gianfranco Silecchia, Roberto Passera, Yoav Mintz
BACKGROUND: The use of 3D laparoscopic systems is expanding. The European Association of Endoscopic Surgery (EAES) initiated a consensus development conference with the aim of creating evidence-based statements and recommendations for the surgical community. METHODS: Systematic reviews of the PubMed and Embase libraries were performed to identify evidence on potential benefits of 3D on clinical practice and patient outcomes. Statements and recommendations were prepared and unanimously agreed by an international surgical and engineering expert panel which were presented and voted at the EAES annual congress, London, May 2018...
December 4, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/30515514/individualized-patient-vocal-priorities-for-tailored-therapy
#10
Ingo R Titze, Tobias Riede, Anil Palaparthi, Linda S Hynan, Amy Hamilton, Laura Toles, Ted Mau
Purpose: The purposes of this study are to introduce the concept of vocal priorities based on acoustic correlates, to develop an instrument to determine these vocal priorities, and to analyze the pattern of vocal priorities in patients with voice disorders. Method: Questions probing the importance of 5 vocal attributes (vocal clarity, loudness, mean speaking pitch, pitch range, vocal endurance) were generated from consensus conference involving speech-language pathologists, laryngologists, and voice scientists, as well as patient feedback...
December 4, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/30511109/-training-in-clinical-acute-and-emergency-medicine-supraspeciality-in-germany-a-concept-for-nationwide-implementation
#11
REVIEW
A Gries, A Seekamp, C Wrede, C Dodt
At the 121st German Physicians Conference 2018 in Erfurt a resolution to accept the full amendment of the (draft) further training regulations (MWBO) was adopted and the State Medical Councils were requested to include them in their respective areas of responsibility. Therefore, the nationwide implementation of the supraspeciality (ZWB) for clinical acute and emergency medicine has been officially finalized. After consultation with the German Medical Council (BÄK) concerning the format, both the new MWBO 2018 and now the content of the ZWB are available as of 15 November 2018...
December 3, 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/30509283/analysis-of-a-real-time-group-consensus-peer-review-process-in-radiation-oncology-an-evaluation-of-effectiveness-and-feasibility
#12
Ashley A Albert, William N Duggar, Rahul P Bhandari, Toms Vengaloor Thomas, Satyaseelan Packianathan, Robert M Allbright, Madhava R Kanakamedala, Divyang Mehta, Chunli Claus Yang, Srinivasan Vijayakumar
BACKGROUND: Peer review systems within radiation oncology are important to ensure quality radiation care. Several individualized methods for radiation oncology peer review have been described. However, despite the importance of peer review in radiation oncology barriers may exist to its effective implementation in practice. The purpose of this study was to quantify the rate of plan changes based on our group peer review process as well as the quantify amount of time and resources needed for this process...
December 3, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/30506632/report-from-the-american-society-of-transplantation-on-frailty-in-solid-organ-transplantation
#13
Jon Kobashigawa, Darshana Dadhania, Sangeeta Bhorade, Deborah Adey, Joseph Berger, Geetha Bhat, Marie Budev, Andres Duarte-Rojo, Michael Dunn, Shelley Hall, Meera N Harhay, Kirsten L Johansen, Susan Joseph, Cassie C Kennedy, Evan Kransdorf, Krista L Lentine, Raymond J Lynch, Mara McAdams-DeMarco, Shunji Nagai, Michael Olymbios, Jignesh Patel, Sean Pinney, Joanna Schaenman, Dorry L Segev, Palak Shah, Lianne G Singer, Jonathan P Singer, Christopher Sonnenday, Puneeta Tandon, Elliot Tapper, Stefan G Tullius, Michael Wilson, Martin Zamora, Jennifer C Lai
A consensus conference on frailty in kidney, liver, heart and lung transplantation, sponsored by the American Society of Transplantation (AST) and endorsed by the American Society of Nephrology (ASN), the American Society of Transplant Surgeons (ASTS) and the Canadian Society of Transplantation (CST), took place on February 11, 2018 in Phoenix, Arizona. Input from the transplant community through scheduled conference calls enabled wide discussion of current concepts in frailty, exploration of best practices for frailty risk assessment of transplant candidates and for management after transplant, and development of ideas for future research...
December 1, 2018: American Journal of Transplantation
https://www.readbyqxmd.com/read/30506111/second-international-consensus-conference-on-lesions-of-uncertain-malignant-potential-in-the-breast-b3-lesions
#14
REVIEW
Christoph J Rageth, Elizabeth A M O'Flynn, Katja Pinker, Rahel A Kubik-Huch, Alexander Mundinger, Thomas Decker, Christoph Tausch, Florian Dammann, Pascal A Baltzer, Eva Maria Fallenberg, Maria P Foschini, Sophie Dellas, Michael Knauer, Caroline Malhaire, Martin Sonnenschein, Andreas Boos, Elisabeth Morris, Zsuzsanna Varga
PURPOSE: The second International Consensus Conference on B3 lesions was held in Zurich, Switzerland, in March 2018, organized by the International Breast Ultrasound School to re-evaluate the consensus recommendations. METHODS: This study (1) evaluated how management recommendations of the first Zurich Consensus Conference of 2016 on B3 lesions had influenced daily practice and (2) reviewed current literature towards recommendations to biopsy. RESULTS: In 2018, the consensus recommendations for management of B3 lesions remained almost unchanged: For flat epithelial atypia (FEA), classical lobular neoplasia (LN), papillary lesions (PL) and radial scars (RS) diagnosed on core-needle biopsy (CNB) or vacuum-assisted biopsy (VAB), excision by VAB in preference to open surgery, and for atypical ductal hyperplasia (ADH) and phyllodes tumors (PT) diagnosed at VAB or CNB, first-line open surgical excision (OE) with follow-up surveillance imaging for 5 years...
November 30, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/30502871/use-of-oral-anticoagulants-in-complex-clinical-situations-with-atrial-fibrillation
#15
Alejandra Gullón, Demetrio Sánchez Fuentes, Esteban López-de-Sá, Julio Martí-Almor, Gonzalo Barón-Esquivias, Jesús Jiménez López, María Del Mar Contreras Muruaga, Carmen Suárez Fernández
The present article provides an update on anticoagulant treatment in patients with atrial fibrillation in distinct clinical scenarios requiring particular considerations, such as ischaemic heart disease, electrical cardioversion, pulmonary vein ablation, the presence of valvular disease with or without prosthetic valves, and renal insufficiency, as well as old age and frailty. In patients with non-valvular atrial fibrillation, the presence of renal insufficiency increases both thrombotic and haemorrhagic risk...
June 2018: Medicina Clínica
https://www.readbyqxmd.com/read/30498971/validation-of-a-new-wind-classification-compared-to-icc-classification-for-weaning-outcome
#16
Byeong-Ho Jeong, Kyeong Yoon Lee, Jimyoung Nam, Myeong Gyun Ko, Soo Jin Na, Gee Young Suh, Kyeongman Jeon
BACKGROUND: Although the WIND (Weaning according to a New Definition) classification based on duration of ventilation after the first separation attempt has been proposed, this new classification has not been tested in clinical practice. The objective of this cohort study was to evaluate the clinical relevance of WIND classification and its association with hospital mortality compared to the International Consensus Conference (ICC) classification. METHODS: All consecutive medical ICU patients who were mechanically ventilated for more than 24 h between July 2010 and September 2013 were prospectively registered...
November 29, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/30498820/international-clinical-practice-guidelines-for-sarcopenia-icfsr-screening-diagnosis-and-management
#17
E Dent, J E Morley, A J Cruz-Jentoft, H Arai, S B Kritchevsky, J Guralnik, J M Bauer, M Pahor, B C Clark, M Cesari, J Ruiz, C C Sieber, M Aubertin-Leheudre, D L Waters, R Visvanathan, F Landi, D T Villareal, R Fielding, C W Won, O Theou, F C Martin, B Dong, J Woo, L Flicker, L Ferrucci, R A Merchant, L Cao, T Cederholm, S M L Ribeiro, L Rodríguez-Mañas, S D Anker, J Lundy, L M Gutiérrez Robledo, I Bautmans, I Aprahamian, J M G A Schols, M Izquierdo, B Vellas
OBJECTIVES: Sarcopenia, defined as an age-associated loss of skeletal muscle function and muscle mass, occurs in approximately 6 - 22 % of older adults. This paper presents evidence-based clinical practice guidelines for screening, diagnosis and management of sarcopenia from the task force of the International Conference on Sarcopenia and Frailty Research (ICSFR). METHODS: To develop the guidelines, we drew upon the best available evidence from two systematic reviews paired with consensus statements by international working groups on sarcopenia...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/30498513/good-clinical-approach-delphi-consensus-for-the-use-of-betahistine-in-meni%C3%A3-re-s-disease
#18
Augusto Pietro Casani, Elena Navari, Giorgio Guidetti, Michel Lacour
Menière's disease is a disorder of the inner ear that causes vertigo, tinnitus, fullness, and hearing loss. Several pharmacological treatments are available, but none of them has shown significant results. Betahistine has been largely used but its effect on the main symptoms of Menière's disease remains unclear. In order to improve clinical appropriateness and to reduce the heterogeneity of the therapeutic approaches for Menière's disease, we proposed a European Consensus Conference on Betahistine's prescription...
2018: International Journal of Otolaryngology
https://www.readbyqxmd.com/read/30498275/report-from-a-consensus-conference-on-the-treatment-of-m%C3%A3-ni%C3%A3-re-s-disease-with-betahistine-rationale-methodology-and-results
#19
A P Casani, G Guidetti, R Schoenhuber
Ménière's disease is a disorder of the inner ear that causes vertigo, tinnitus, fullness and hearing loss. Although several treatments are available, the success rate is reported to be around 70%, similar to placebo. Betahistine, a weak H1 receptor agonist and an effective H3 receptor antagonist, is frequently prescribed for Ménière's disease, especially to reduce recurrent vertigo attacks. The effects of this drug on hearing and other audiological symptoms remains unclear. Given the inconclusive reports in the literature, we proposed a consensus conference on the use of betahistine in Ménière's disease...
October 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/30498170/toothbrushing-should-we-advise-mechanical-or-power-brushes-results-of-an-international-delphi-conference
#20
Crawford Bain, Arwa Al Sayed, Eleftherios G Kaklamanos, Hizbullah Aa Kazi
BACKGROUND AND AIM: To develop evidence-based answers to a series of questions in relation to toothbrushing using a modified Delphi consensus approach. Oral hygiene and especially toothbrushing have been a fundamental part of the efforts to prevent caries and gingivitis. The questions discussed involved the frequency and duration of brushing, the effectiveness and safety of powered brushes and the recommendations for children and orthodontic patients. REVIEW RESULTS: The Delphi panel agreed that twice daily brushing for 2 minutes and a systematic pattern is advised...
October 1, 2018: Journal of Contemporary Dental Practice
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