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https://www.readbyqxmd.com/read/30334066/dosimetric-and-volumetric-effects-in-clinical-target-volume-and-organs-at-risk-during-postprostatectomy-radiotherapy
#1
Ahmed Gawish, Ahmed Ali Chughtai, Michael J Eble
PURPOSE: To assess the reproducibility of the dose-volume distribution of the initial simulation CT, generated using volumetric modulated arc therapy (VMAT) planning, during the radiotherapy of the prostatic bed based on weekly cone beam CTs (CBCT). METHODS: Twenty-three patients, after radical prostatectomy were treated with adjuvant or salvage radiotherapy between July and December 2016 and considered for this evaluation. Weekly CBCT scans (n = 138) were imported into the treatment planning system, and the clinical tumor volume (CTV), the rectum and the bladder were contoured...
October 17, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/30333277/an-interesting-case-of-hepatic-adrenocortical-carcinoma
#2
Hikmat Permana, Guntur Darmawan, Ervita Ritonga, Maya Kusumawati, Miftahurachman Miftahurachman, Nanny Natalia Soetedjo
Adrenocortical carcinoma (ACC) is a rare solid tumor with an incidence of 0.5 to 2 cases per million per year. It affects women more commonly than men with a ratio of 1.5:1. Ectopic ACC are considered to be extremely rare with no exact incidence data yet. We report an interesting case of hepatic ACC in a young woman with clinical signs of virilization.A-21-year old Sundanese woman visited our endocrine clinic with progressive hirsutism over the face, body, and extremities starting 14 years previously. She had irregular, heavy periods when she was 7 years old...
July 2018: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/30328624/multi-region-segmentation-of-bladder-cancer-structures-in-mri-with-progressive-dilated-convolutional-networks
#3
Jose Dolz, Xiaopan Xu, Jérôme Rony, Jing Yuan, Yang Liu, Eric Granger, Christian Desrosiers, Xi Zhang, Ismail Ben Ayed, Hongbing Lu
PURPOSE: Precise segmentation of bladder walls and tumor regions is an essential step towards non-invasive identification of tumor stage and grade, which is critical for treatment decision and prognosis of patients with bladder cancer (BC). However, the automatic delineation of bladder walls and tumor in magnetic resonance images (MRI) is a challenging task, due to important bladder shape variations, strong intensity inhomogeneity in urine and very high variability across population, particularly on tumors appearance...
October 17, 2018: Medical Physics
https://www.readbyqxmd.com/read/30325819/imaging-characteristics-of-a-bladder-wall-paraganglioma
#4
Andrew John Bosserman, Dong Dai, Yang Lu
A 65-year-old man with a history of hypertension and nephrolithiasis presented with flank pain. Urographic CT demonstrated a 1.7-cm nodule arising from the bladder wall. The patient was referred for cystourethroscopy. During the procedure, the patient became hypertensive while under general anesthesia. No biopsy or resection was performed. To work up for possible bladder paraganglioma, a I-MIBG scan was ordered, and the patient was referred to endocrinology. On SPECT/CT images, the bladder nodule demonstrates marked uptake of MIBG radiotracer, confirming the diagnosis of a genitourinary paraganglioma arising from the bladder wall...
October 15, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/30325783/accuracy-of-bladder-scanner-for-the-assessment-of-postvoid-residual-volumes-in-women-with-pelvic-organ-prolapse
#5
Danielle Lynn Taylor, Tania Sierra, Omar Felipe Duenas-Garcia, Youngwu Kim, Katherine Leung, Cynthia Hall, Michael K Flynn
OBJECTIVES: The aim of the study was to evaluate the accuracy of the bladder scanner in assessing postvoid residual (PVR) volumes in patients with pelvic organ prolapse (POP). METHODS: We performed a prospective parallel cohort study evaluating the accuracy of the BVI 3000 bladder scanner in patients with POP. Patients with POP to the hymen were offered inclusion. Primary outcome was the absolute difference between bladder scanner and catheterization PVR. We also investigated the effect of prolapse stage on bladder scanner accuracy...
October 15, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/30324464/imaging-study-of-pseudo-ct-images-of-superposed-ultrasound-deformation-fields-acquired-in-radiotherapy-based-on-step-by-step-local-registration
#6
Hongfei Sun, Tao Lin, Kai Xie, Liugang Gao, Jianfeng Sui, Xinye Ni
The purpose of this study is to create a new pseudo-computed tomography (CT) imaging approach under superposed ultrasound (US) deformation fields based on step-by-step local registration. Scanned CT and US 3D image datasets of three patients with postoperative cervical carcinoma were selected, including CT (CTsim) and US images (USsim) acquired during simulated positioning process and cone beam CT (CBCT) and US images for positioning verification (USpv) acquired after treatment for 10 times. Regions of interest such as urinary bladders were segmented out and accepted local registration to obtain different deformation fields...
October 15, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/30323939/guillain-barr%C3%A3-syndrome-associated-with-bladder-instillation-of-bacille-calmette-gu%C3%A3-rin-bcg
#7
Karmel Webb, Pradhib Venkatesan
Introduction: Guillain Barré Syndrome (GBS) has rarely been associated with tuberculosis and has been previously reported after Bacille Calmette Guérin (BCG) vaccination, but we report an association of GBS with intra-vesical BCG instillations followed by the clinical picture of disseminated BCGosis. Case presentation: A 68-year-old man with bladder carcinoma had a transurethral tumour resection followed by repeated BCG instillations. Catheterization for his eighth dose was traumatic, causing frank haematuria...
August 2018: JMM Case Reports
https://www.readbyqxmd.com/read/30323935/a-case-of-hepato-biliary-infection-secondary-to-cryptosporidium-in-a-patient-on-tacrolimus
#8
Sajal Gupta, Alison Johnson, Simon Meyrick, Angharad P Davies, R Chalmers
Introduction: Cryptosporidium infection is known to cause hepato-biliary involvement, mainly in association with T-cell immune deficiency. Hepato-biliary involvement in association with milder immunosuppression is less well described. We describe the first case, to our knowledge, of Cryptosporidium hominis hepato-biliary infection associated with tacrolimus in a patient with nephrotic syndrome. Case presentation: A 14 year old girl who had been on tacrolimus for nephrotic syndrome presented with diarrhea due to C...
August 2018: JMM Case Reports
https://www.readbyqxmd.com/read/30318333/-french-ccafu-guidelines-update-2018-2020-upper-tract-urothelial-carcinoma
#9
M Rouprêt, E Xylinas, P Colin, N Houédé, E Compérat, F Audenet, S Larré, A Masson-Lecomte, G Pignot, S Brunelle, M Roumiguié, Y Neuzillet, A Méjean
INTRODUCTION: To propose an update of the French guidelines from the national committee ccAFU on upper tract urothelial carcinomas (UTUC). METHODS: A systematic Medline search was performed between 2016 and 2018, with regards to the diagnosis, the options of treatment and the follow-up of UTUC, to evaluate the different studies with levels of evidence. RESULTS: The diagnosis of this rare disease is based on CT-scan acquisition during excretion and ureteroscopy with histological biopsies...
October 11, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/30317855/colonic-malignant-melanoma-18-f-fdg-pet-ct-findings
#10
Eser Kaya, Tamer Aksoy, Ahmet Levent Güner, Hakan Temiz, Erkan Vardareli
Primary malignant melanoma occurs most often in the skin and much less frequently in the choroid layer of the eyes, in the leptomeninges, oral cavity, nasal mucosa, pharynx, esophagus, bronchus, under the nail and vaginal or anorectal mucosa. Primary melanoma of the gastrointestinal tract has been confirmed for lesions occurring in the esophagus, stomach, small bowel, and anorectum through several published reports, as these are the areas where melanocytes normally exist. The occurrence of primary malignant melanoma in the colon is relatively rare, because melanocytes are embryologically absent in the large bowel...
October 9, 2018: Molecular Imaging and Radionuclide Therapy
https://www.readbyqxmd.com/read/30310640/thoracic-spinal-cord-injury-without-radiologic-abnormality-in-a-pediatric-patient-case-report
#11
Juan Iaconis Campbell, Federico Coppola, Emilio Volpe, Eduardo Salas Lopez
Spinal Cord Injury Without Radiologic Abnormality (SCIWORA) accounts for up to 19% of spinal cord related lesions in pediatric population, mostly comprising the cervical spine. A 2-year-old patient is presented, who suffered a motor-vehicle accident. After being admitted, neither X-Ray nor spinal TC scan showed any structural abnormalities. Neurological examination showed complete sensory and motor loss under T7 as well as bladder and bowel dysfunction. Magnetic resonance imaging (MRI) showed spinal cord lesion extending from T7 to T10...
October 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/30309215/assessment-of-inter-and-intra-fractional-volume-of-bladder-and-body-contour-by-mega-voltage-computed-tomography-in-helical-tomotherapy-for-pelvic-malignancy
#12
Sunghyun Kim, Sei Hwan You, Young Ju Eum
PURPOSE: We describe the daily bladder volume change observed by mega-voltage computed tomography (MVCT) during pelvic radiotherapy with potential predictors of increased bladder volume variations. Materials and METHODS: For 41 patients who received pelvic area irradiation, the volumes of bladder and pelvic body contour were measured twice a day with pre- and post-irradiation MVCT from the 1st to the 10th fraction. The median prescription dose was 20 Gy (range, 18 to 30 Gy) up to a 10th fraction...
September 2018: Radiation Oncology Journal
https://www.readbyqxmd.com/read/30303415/the-effect-of-air-pockets-in-the-urinary-bladder-on-the-temperature-distribution-during-loco-regional-hyperthermia-treatment-of-bladder-cancer-patients
#13
G Schooneveldt, H P Kok, A Bakker, E D Geijsen, M C C M Hulshof, T M de Reijke, J Crezee
PURPOSE: Loco-regional hyperthermia combined with mitomycin C is used for treatment of nonmuscle invasive bladder cancer (NMIBC). Air pockets may be present in the bladder during treatment. The aim of this study is to quantify the effect of air pockets on the thermal dose of the bladder. METHODS: We analysed 16 patients treated for NMIBC. Loco-regional hyperthermia was performed with the in-house developed 70 MHz AMC-4 hyperthermia device. We simulated treatments with the clinically applied device settings using Plan2Heat (developed in-house) including the air pockets delineated on CT scans made following treatment, and with the same volume filled with urine...
October 10, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/30300028/predictive-value-of-simulated-sar-and-temperature-for-changes-in-measured-temperature-after-phase-amplitude-steering-during-locoregional-hyperthermia-treatments
#14
H P Kok, G Schooneveldt, A Bakker, R de Kroon-Oldenhof, L Korshuize-van Straten, C E de Jong, E Steggerda-Carvalho, E D Geijsen, L J A Stalpers, J Crezee
INTRODUCTION: On-line adaptive hyperthermia treatment planning can be useful to suppress treatment limiting hot spots and improve tumor temperatures during locoregional hyperthermia. This requires adequate prediction of changes in heating patterns after phase-amplitude steering. We investigated the predictive value of simulated SAR and temperature for changes in measured temperature after phase-amplitude steering during locoregional hyperthermia. METHODS: All treatment sessions of 75 patients with pelvic malignancies treated between September 2013 and March 2018 were evaluated...
October 9, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/30298195/the-clinical-features-and-outcome-of-scan-negative-and-scan-positive-cases-in-suspected-cauda-equina-syndrome-a-retrospective-study-of-276-patients
#15
Ingrid Hoeritzauer, Savva Pronin, Alan Carson, Patrick Statham, Andreas K Demetriades, Jon Stone
BACKGROUND: The majority of patients presenting with suspected clinical cauda equina syndrome (CES) have no identifiable structural cause for their symptoms ('scan-negative' CES). Understanding these patients aids clinical differentiation and management in CES. METHODS: A retrospective electronic note review was undertaken of patients presenting with suspected CES, defined as ≥ 1 of acute bladder, bowel, sexual dysfunction or saddle numbness, to a regional neurosciences centre...
October 8, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/30284370/evaluation-of-offline-adaptive-planning-techniques-in-image-guided-brachytherapy-of-cervical-cancer
#16
Han Liu, James Kinard, Jacqueline Maurer, Qingyang Shang, Caroline Vanderstraeten, Lane Hayes, Benjamin Sintay, David Wiant
Modern three-dimensional image-guided intracavitary high dose rate (HDR) brachytherapy is often used in combination with external beam radiotherapy (EBRT) to manage cervical cancer. Intrafraction motion of critical organs relative to the HDR applicator in the time between the planning CT and treatment delivery can cause marked deviations between the planned and delivered doses. This study examines offline adaptive planning techniques that may reduce intrafraction uncertainties by shortening the time between the planning CT and treatment delivery...
October 3, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/30283204/sonographic-diagnosis-of-a-colovesical-fistula-due-to-sigmoid-colon-cancer
#17
Dal Mo Yang, Hyun Cheol Kim, Sang Won Kim, Sung Jig Lim, Ji Su Kim
Based on sonographic findings, colovesical fistula was diagnosed in a 71-year-old man with sigmoid colon cancer. Gray-scale sonography revealed an irregular thickening of the sigmoid colon wall abutting the urinary bladder which also showed thickening in the region of contact. Color Doppler sonography showed a twinkling artifact within the thickened bladder wall. Contrast-enhanced computed tomography scan showed luminal communication between the sigmoid colon and the bladder in the region of thickening.
July 2018: Journal of Medical Ultrasound
https://www.readbyqxmd.com/read/30280699/prevascularized-bladder-acellular-matrix-hydrogel-silk-fibroin-composite-scaffolds-promote-the-regeneration-of-urethra-in-a-rabbit-model
#18
Nailong Cao, Lu-Jie Song, Wenjing Liu, Suna Fan, Dan Jiang, Jiagui Mu, Baojun Gu, Yuemin Xu, YaoPeng Zhang, Jianwen Huang
To evaluate the effects of urethral regeneration with prevascularized bladder acellular matrix hydrogel (BAMH)/silk fibroin (SF) composite scaffolds in a rabbit model.
 Materials and methods: BAMH/SF and collagen TypeⅠhydrogel /SF (CH/SF) scaffold were prepared and the structure of the scaffolds was assessed using scanning electron microscopy. BAMH/SF, CH/SF and SF scaffold were incubated in the omentum of male rabbits for 2 weeks and then harvested for repairing autologous urethral defects. Histological analysis of the incubated scaffolds was performed to evaluate the neovascularization capacity, and the outcomes of urethroplasty were evaluated at one and three months post-operatively...
October 3, 2018: Biomedical Materials
https://www.readbyqxmd.com/read/30276560/long-term-clinical-radiological-and-histological-follow-up-after-complex-ventral-incisional-hernia-repair-using-urinary-bladder-matrix-graft-reinforcement-a-retrospective-cohort-study
#19
K C Sasse, J-H Lambin, J Gevorkian, C Elliott, R Afshar, A Gardner, A Mehta, R Lambin, L Peraza
BACKGROUND: Complex ventral incisional hernia repair represents a challenging clinical condition in which biologically derived graft reinforcement is often utilized, but little long-term data inform that decision. Urinary bladder matrix (UBM) has shown effectiveness in diverse clinical settings as durable reinforcement graft material, but it has not been studied over a long term in ventral incisional hernia repair. This study evaluates the clinical, radiographic, and histological outcome of complex incisional hernia repair using UBM reinforcement with 12-70 months of follow-up...
October 1, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/30270701/value-and-necessity-of-pelvic-ct-in-gastric-cancer-staging-an-observational-study
#20
Jing Li, Yang Tan, Die Zhang, Jiawei Li, Shuang Shen, Yebin Jiang, Jianlin Wu
BACKGROUND: The value and necessity of pelvic computed tomography (CT) examination in gastric cancer (GC) staging is unknown and the recommendations are unclear in guidelines. The objective of this study was to evaluate the value and necessity of pelvic CT in routine GC staging. METHODS: We reviewed the medical records of GC patients proved by endoscopic biopsy who received abdominopelvic CT examination before treatments at our institution from January 2013 through July 2017...
September 29, 2018: Scandinavian Journal of Gastroenterology
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