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https://www.readbyqxmd.com/read/30544437/minimally-invasive-surgery-for-inflammatory-myofibroblastic-tumor-of-the-urinary-bladder-three-case-reports
#1
He Xu, Ben He, Xiang Tu, Yige Bao, Lu Yang, Hui Zhuo, Qiang Wei
RATIONALE: Inflammatory myofibroblastic tumors of the urinary bladder (IMTUB) is exceptionally rare. Currently, no standardized treatment has been established for IMTUBs. PATIENT CONCERNS: Herein we report three cases presenting with hematuria and anemia. A 25-year-old man experienced painless gross hematuria for 2 days and the hemoglobin level continuously dropped to 88 g/L; a 72-year-old man complaining of gross hematuria for seven days; and a 33-year-old woman presenting with gross hematuria, urgency, and frequency for the duration of 20 days, with a hemoglobin level of 61 g/L...
December 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30543050/first-in-human-radiation-dosimetry-of-the-gastrin-releasing-peptide-grp-receptor-antagonist-68-ga-nodaga-mj9
#2
Silvano Gnesin, Francesco Cicone, Periklis Mitsakis, Axel Van der Gucht, Sébastien Baechler, Raymond Miralbell, Valentina Garibotto, Thomas Zilli, John O Prior
BACKGROUND: Gastrin-releasing peptide receptor antagonists have promise in theranostics of several highly incident tumours, including prostate and breast. This study presents the first human dosimetry of 68 Ga-NODAGA-MJ9 in the first five consecutive patients with recurrent prostate cancer included in a dual-tracer positron emission tomography (PET) protocol. Five male patients with biochemical relapse of prostate adenocarcinoma underwent four whole-body time-of-flight PET/CT scans within 2 h after tracer injection...
December 12, 2018: EJNMMI Research
https://www.readbyqxmd.com/read/30527482/availability-of-common-pediatric-radiology-studies-are-rural-patients-at-a-disadvantage
#3
Jorge A Whitley, Shruthie Gnaneswaran, Molly Thach, Amy C Taylor, Paul A Merguerian, Kathleen Kieran
BACKGROUND: Many families wish to have radiologic tests performed locally, especially when obtaining these tests in specialized pediatric centers would require long-distance travel with associated costs and inconveniences. The differential availability of specialized and common pediatric uroradiographic tests in rural and urban areas has not been described. We undertook this study to describe the availability of common radiographic tests ordered by pediatric urologists, and to identify disparities in the availability of radiographic tests between urban and rural locations...
February 2019: Journal of Surgical Research
https://www.readbyqxmd.com/read/30523435/biodistribution-pharmacokinetics-and-organ-level-dosimetry-for-188-re-ahdd-lipiodol-radioembolization-based-on-quantitative-post-treatment-spect-ct-scans
#4
Pedro L Esquinas, Ajit Shinto, Koramadai K Kamaleshwaran, Jephy Joseph, Anna Celler
BACKGROUND: Rhenium-188-labelled-Lipiodol radioembolization is a safe and cost-effective treatment for primary liver cancer. In order to determine correlations between treatment doses and patient response to therapy, accurate patient-specific dosimetry is required. Up to date, the reported dosimetry of 188 Re-Lipiodol has been based on whole-body (WB) planar imaging only, which has limited quantitative accuracy. The aim of the present study is to determine the in vivo pharmacokinetics, bio-distribution, and organ-level dosimetry of 188 Re-AHDD-Lipiodol radioembolization using a combination of post-treatment planar and quantitative SPECT/CT images...
December 7, 2018: EJNMMI Physics
https://www.readbyqxmd.com/read/30510852/-68-ga-psma-11-pet-ct-in-prostate-cancer-local-recurrence-impact-of-early-images-and-parametric-analysis
#5
Christos Sachpekidis, Leyun Pan, Boris A Hadaschik, Klaus Kopka, Uwe Haberkorn, Antonia Dimitrakopoulou-Strauss
68 Ga-PSMA-11 PET/CT performed 60 min post tracer injection (p.i.) can underestimate prostate cancer (PC) local recurrence, due to high 68 Ga-PSMA-11 urinary bladder accumulation. Aim of this analysis is to evaluate the complementary role of early dynamic and parametric PET imaging in patients with PC local recurrence. Sixteen patients with PC biochemical relapse attributed to local recurrence underwent dynamic 68 Ga-PSMA-11 PET/CT scanning of the pelvis and whole-body PET/CT. Data analysis was based on visual analysis of the PET/CT scans, SUV calculations, quantitative analysis based on two-tissue compartment and Patlak models as well as parametric imaging based on Patlak analysis...
2018: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/30509988/noninvasive-diagnostic-imaging-using-machine-learning-analysis-of-nanoresolution-images-of-cell-surfaces-detection-of-bladder-cancer
#6
I Sokolov, M E Dokukin, V Kalaparthi, M Miljkovic, A Wang, J D Seigne, P Grivas, E Demidenko
We report an approach in diagnostic imaging based on nanoscale-resolution scanning of surfaces of cells collected from body fluids using a recent modality of atomic force microscopy (AFM), subresonance tapping, and machine-leaning analysis. The surface parameters, which are typically used in engineering to describe surfaces, are used to classify cells. The method is applied to the detection of bladder cancer, which is one of the most common human malignancies and the most expensive cancer to treat. The frequent visual examinations of bladder (cytoscopy) required for follow-up are not only uncomfortable for the patient but a serious cost for the health care system...
December 3, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/30488269/validation-study-of-ultrasound-bladder-wall-thickness-measurements
#7
Victoria Asfour, Kayleigh Gibbs, Ana Sophia DaSilva, Ruwan Fernando, Guiseppe Alessandro Digesu, Vik Khullar
INTRODUCTION AND HYPOTHESIS: The aim was to validate ultrasound bladder wall thickness measurements. We scanned at three frequencies (5 MHz, 7 MHz and 9 MHz), using two techniques described in clinical practice and compared them with direct micrometre calliper measurements. METHODS: Bladder dome cadaver specimens were dissected from male and female cadavers. The direct micrometre calliper measurement under direct vision was used as the gold standard. We imaged using a Voluson E8 ultrasound scanner at three frequencies, using three probes: AB27D (2-7 MHz), RAB25D (2-5 MHz) and RIC50D (5-9 MHz)...
November 28, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/30487042/diagnosis-and-treatment-of-inguinal-hernia-of-the-bladder-a-systematic-review-of-the-past-10-years
#8
REVIEW
Benjamin Branchu, Yohann Renard, Stephane Larre, Priscilla Leon
OBJECTIVE: Inguinoscrotal hernia (ISH) of the bladder is a rare condition involved in less than 4% of inguinal hernias. In most cases, it occurs to men older than 50 years who are overweight. Little is known about the subject and mainly based on case reports. When undiagnosed, it may be associated with bladder injuries during hernia repair. There is also no consensus on the ideal repair technique to use. The aim of the study is to evaluate the particularity of the management of the inguinal herniation of the bladder in term of diagnosis, choice and results of treatments...
September 2018: Turkish Journal of Urology
https://www.readbyqxmd.com/read/30484768/utility-of-mitrofanoff-as-bladder-draining-tool-a-single-center-experience-in-pediatric-patients
#9
Nadeem Iqbal, Omar Zia Syed, Amna Haider Bukhari, Abdul Ahad Ehsan Sheikh, Umair Syed Mahmud, Faheemullah Khan, Ijaz Hussain, Saeed Akhter
OBJECTIVE: Mitrofanoff procedure has been employed commonly as bladder draining tool in patients unable to do clean intermittent self catheterization through native urethera. Single centre experience of pediatric age group patients undergoing Mitrofanoff procedure has been presented here. MATERIAL AND METHODS: It was a retrospective study of 29 children who underwent continent catheterizable conduit (CCC), from January 2009 till March 2017. Charts were reviewed for age, gender, presenting complaints, need for augmentation cystoplasty, Mitrofanoff channel source such as appendix or ileal patch, duration of surgery in minutes, hospital stay in days, per operative and postoperative complications...
November 26, 2018: Turkish Journal of Urology
https://www.readbyqxmd.com/read/30465543/autosegmentation-of-prostate-anatomy-for-radiation-treatment-planning-using-deep-decision-forests-of-radiomic-features
#10
Meghan W Macomber, Mark Phillips, Ivan Tarapov, Rajesh Jena, Aditya Nori, David Carter, Loic Le Folgoc, Antonio Criminisi, Matthew J Nyflot
Machine learning for image segmentation could provide expedited clinic workflow and better standardization of contour delineation. We evaluated a new model using deep decision forests of image features in order to contour pelvic anatomy on treatment planning CTs. 193 CT scans from one UK and two US institutions for patients undergoing radiotherapy treatment for prostate cancer from 2012-2016 were anonymized. A decision forest autosegmentation model was trained on a random selection of 94 images from Institution 1 and tested on 99 scans from Institution 1, 2, and 3...
November 22, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/30455826/-collection-in-the-thigh-revealing-bladder-fistula-after-radiotherapy-for-prostate-cancer
#11
Soufiane Ennaciri, Toufik Michel Bitard
Urinary fistulas are a rare late complication after radiotherapy for prostate cancer. We here report the case of a 76-year old patient who had undergone radical prostatectomy 4 years before followed by external beam radiotherapy for prostate cancer. The patient presented with recurrent thigh swelling . Clinical examination showed renitent and painless mass at the level of the medial compartment of the right thigh. Ultrasound followed by CT scan showed big homogeneous fluid collection in the inner thigh exercising a slight compression on femoral vessels...
2018: Pan African Medical Journal
https://www.readbyqxmd.com/read/30448821/-emphysematous-cystitis-in-a-patient-with-type-1diabetes-mellitus-diagnostic-difficulties
#12
Małgorzata Hadzik-Błaszczyk, Tadeusz M Zielonka, Renata Krupa, Tomasz Rusinowicz, Katarzyna Życińska
A case report of 28 year old female with medical history of bed controlled type 1 diabetes mellitus complicated by autonomic neuropathy in the form of gastroparesis, suffered by emphysematous cystitis caused by Escherichia coli was described. Emphysematous cystitis is a rare urinary tract infection connected with the presence of gas in the bladder lumen or/and within the bladder wall, which occurs mainly in women, in older age, suffering from type 2 diabetes, complicated by microangiopathy, neuropathy, with urinary tract obstruction and weakness of immunity system...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/30431591/ureteral-inflammatory-myofibroblastic-tumor-a-case-report-and-literature-review
#13
Faping Li, Hui Guo, Heping Qiu, Yuchuan Hou
RATIONALE: Inflammatory myofibroblastic tumor (IMT) is a rare soft-tissue neoplasm which has been described in a variety of locations. In the urogenital system, IMT predominantly occurs in the bladder and the kidney. IMT arising from the ureter is exceedingly rare and has been sporadically reported before. PATIENT CONCERNS: We reported an extremely exceptional case of IMT arising from the ureteral submucosa in a 54-year-old man. The patient was hospitalized with the main complaint of intermittent and moderate left abdominal pain for 2 months...
November 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30428857/rare-case-of-neglected-large-sacral-chordoma-in-a-young-female-treated-by-wide-en-bloc-resection-and-sacrectomy
#14
Zi Hao Phang, Xue Yi Saw, Noreen Fadzlina Binti Mat Nor, Zolqarnain Bin Ahmad, Sa'adon Bin Ibrahim
BACKGROUND: Sacral chordoma is a locally aggressive malignant tumour originating from ectopic notochordal cells. The natural history of sacral chordoma is a slow growing tumour arising at the midline of the lower sacrum that can invade the sacrum and progressively increase in size expanding cranially and anteriorly. Metastasis is very rare even when the tumour is large. Sacral chordoma affects males more than females and is more commonly found in middle age and elderly patients. CASE PRESENTATION: A 25 years old female had neglected an extremely large midline sacral mass for 2 years...
November 14, 2018: BMC Cancer
https://www.readbyqxmd.com/read/30427778/learning-from-tragedy-the-julia-berg-story
#15
Mark L Graber, Dan Berg, Welcome Jerde, Phillip Kibort, Andrew P J Olson, Vinita Parkash
This is a case report involving diagnostic errors that resulted in the death of a 15-year-old girl, and commentaries on the case from her parents and involved providers. Julia Berg presented with fatigue, fevers, sore throat and right sided flank pain. Based on a computed tomography (CT) scan that identified an abnormal-appearing gall bladder, and markedly elevated bilirubin and "liver function tests", she was hospitalized and ultimately underwent surgery for suspected cholecystitis and/or cholangitis...
November 27, 2018: Diagnosis
https://www.readbyqxmd.com/read/30427132/trus-guided-drainage-of-the-ectopic-ureter-entering-the-prostatic-urethra-and-trus-guided-transurethral-neo-orifice-formation-using-holmium-laser
#16
Waldemar Białek, Ewa Mey, Piotr Kawecki, Roman Styliński, Sławomir Rudzki
A fifty-nine year-old male was hospitalized for exacerbation of chronic pancreatitis. As a gigantic cyst of the pancreatic tail was identified, it was fused with the jejunal loop. Due to persistent fever and severe symptoms in the storage and voiding phases, the patient was referred to a urologist. Because transrectal ultrasound examination revealed a fluid collection resembling the left seminal vesicle filled with purulent material, a transrectal puncture procedure was performed. The analysis of computed tomography scans led to the diagnosis of duplicated collecting system of the left kidney with the enormous ureter of the upper moiety that entered the prostate gland...
2018: Journal of Ultrasonography
https://www.readbyqxmd.com/read/30426863/evaluation-of-the-bioactivity-about-anti-sca-1-basic-fibroblast-growth-factor-urinary-bladder-matrix-scaffold-for-pelvic-reconstruction
#17
Jiankui Li, Xi Chen, Kaijian Ling, Zhiqing Liang, Huicheng Xu
Introduction and hypothesis: Pelvic support structure injury is the major cause of pelvic organ prolapse. At present, polypropylene-based filler material has been suggested as a common method to treat pelvic organ prolapse. However, it cannot functionally rehabilitate the pelvic support structure. In addition to its poor long-term efficiency, the urinary bladder matrix was the most suitable biological scaffold material for pelvic floor repair. Here, we hypothesize that anti-sca-1 monoclonal antibody and basic fibroblast growth factor were cross-linked to urinary bladder matrix to construct a two-factor bioscaffold for pelvic reconstruction...
November 14, 2018: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/30426074/clear-cell-renal-cell-carcinoma-with-a-ureteral-thrombus
#18
Jeff John, Alessandro P Aldera, Sunil Sinha, John Lazarus
Introduction: Cancers of the kidney, arising from either the renal parenchymal tissue or the renal pelvis, is among the 13 commonest types of malignancy globally, accounting for between 3% and 4% of all newly diagnosed cancers. Renal cell carcinoma (RCC) accounts for 85% of all malignant renal neoplasms. We present a rare case of an RCC directly extending into the renal pelvicalyceal system and with a thrombus within the ureter. Case Presentation: A 39-year-old woman presented with a long-standing history of worsening left flank pain, intermittent visible hematuria, and a fullness in the left flank...
2018: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/30424999/diagnostic-accuracy-of-ct-for-prediction-of-bladder-cancer-treatment-response-with-and-without-computerized-decision-support
#19
Kenny H Cha, Lubomir M Hadjiiski PhD, Richard H Cohan Md, Heang-Ping Chan PhD, Elaine M Caoili Md, Matthew Davenport Md, Ravi K Samala PhD, Alon Z Weizer Md, Ajjai Alva Md, Galina Kirova-Nedyalkova Md PhD, Kimberly Shampain Md, Nathaniel Meyer Md, Daniel Barkmeier Md PhD, Sean Woolen Md, Prasad R Shankar Md, Isaac R Francis Md, Phillip Palmbos Md
RATIONALE AND OBJECTIVES: To evaluate whether a computed tomography (CT)-based computerized decision-support system for muscle-invasive bladder cancer treatment response assessment (CDSS-T) can improve identification of patients who have responded completely to neoadjuvant chemotherapy. MATERIALS AND METHODS: Following Institutional Review Board approval, pre-chemotherapy and post-chemotherapy CT scans of 123 subjects with 157 muscle-invasive bladder cancer foci were collected retrospectively...
November 10, 2018: Academic Radiology
https://www.readbyqxmd.com/read/30417050/hyperthermic-intravesical-chemotherapy-for-bcg-unresponsive-non-muscle-invasive-bladder-cancer-patients
#20
Joep J de Jong, Kees Hendricksen, Marloes Rosier, Hugh Mostafid, Joost L Boormans
Background: Adjuvant intravesical instillations with bacillus Calmette-Guérin (BCG) is the recommended treatment option for patients with intermediate-and high-risk non-muscle invasive bladder cancer (NMIBC). Despite adequate BCG treatment, a large proportion of patients experience a recurrence. Although radical cystectomy is the gold standard for BCG unresponsive NMIBC, some patients are unfit or unwilling to consider this option. Objective: To assess the effectiveness of Hyperthermic IntraVEsical Chemotherapy (HIVEC® ) in BCG unresponsive NMIBC patients...
October 29, 2018: Bladder Cancer
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