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Mathieu Pinelli, Sonia Pellissier, Clémentine Bry
We tested a field-adapted priming procedure (a technique used to subtly activate mental representations and guide behavior) on a ski slope, with the goal of reducing risk behavior in winter sports. At cableway stations, skiers were initially exposed eight times to a prevention poster displaying a logo and a "slow down" message. The "slow down" concept was activated on the ski slope by exposing skiers (or not) 10 times to the logo featured on the poster. We used a radar device to measure the skiers' speed data just before a slope intersection...
August 17, 2018: Journal of Primary Prevention
Clémentine Brun, Nicolas Giorgi, Anne-Marie Pinard, Martin Gagné, Candida S McCabe, Catherine Mercier
Chronic pain is often accompanied by patient reported distorted body perception and an altered kinesthesia (referring to the senses of limb position and limb movement), but the association between these deficits is unknown. OBJECTIVES: 1- to assess body perception, and the senses of limb position and limb movement in Complex Regional Pain Syndrome (CRPS); 2- to test whether these variables are related to each other and to pain intensity. Thirteen upper limb CRPS (mean pain intensity: 4...
August 9, 2018: Journal of Pain: Official Journal of the American Pain Society
Kun Wang, Chun-Zhi Tang, Xiao-Ting Tian, Ming-Zhu Li, Xin-Sheng Lai
OBJECTIVE: To analyze the regularity of acupoint selection, main acupoints and theoretical basis in acupuncture treatment of urticaria. METHODS: Papers collected from the time of establishment of each database to September of 2017 were retrieved from databases CNKI, CBM, VIP and WF by using keywords of "acupuncture" "moxibustion" "blood-letting therapy" "autohemotherapy" "cupping" "acupoint catgut embedding" "auricular points" "acupoint injection" "fire-needle" (or red-hot needle), "dermal needle" "needle-embedding" "urticaria" in both Chinese and English...
June 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
Antoine Sanon, Ilboudo Zakaria, Dabire-Binso Clémentine L, Ba Malick Niango, Nébié Roger Charles Honora
Cowpea is an essential food legume in the tropics and particularly for sub-Saharan African populations. Postharvest grain storage, however, is a major constraint for crop expansion and year-round availability due to the cowpea weevil, Callosobruchus maculatus F., the main storage pest of cowpeas in West Africa. The use of chemicals for cowpea storage is a common practice which represents, however, a risk for consumers, environment, and could also exacerbate pest control. In Burkina Faso, since the early 2000s, several scientific investigations have focused on the control of C maculatus using botanicals considered as promising and safe alternatives to chemicals...
2018: International Journal of Insect Science
Clémentine Riault, Mathurin Fumery, Jean-Philippe Le Mouel
No abstract text is available yet for this article.
August 3, 2018: Clinical Gastroenterology and Hepatology
Hedi Chabanol, Olivier Huillard, Lucie Prin, Clémentine Villeminey, Aurélie Rondeau, Pascaline Boudou-Rouquette, Florence Astorg, Beatrice Musenghesi, Catherine Du Mortier, Jerome Alexandre, Francois Goldwasser
BACKGROUND: Docetaxel is frequently used for the treatment of metastatic prostate cancer patients. Nail toxicity is a commonly described side effect, but no precise recommendation exists concerning its management. We experimented the integration of a podiatrist in routine cancer care. METHODS: Patients having received docetaxel for a metastatic prostate cancer since the arrival of the podiatrist were studied. RESULTS: Fifty-six patients were included, half had docetaxel-induced nail toxicity and 18 were referred to the podiatrist...
August 2, 2018: Bulletin du Cancer
Massimo Federico, María Dolores Caballero Barrigón, Luigi Marcheselli, Vittoria Tarantino, Martina Manni, Clementine Sarkozy, Sara Alonso-Álvarez, Marielle Wondergem, Guillaume Cartron, Armando Lopez-Guillermo, Djamila Issa, Franck Morschhauser, Miguel Alcoceba, Eva Kimby, Chiara Rusconi, Martine Chamuleau, Harald Holte, Sandra Lockmer, Silvia Montoto, Maria Gomes da Silva, Igor Aurer, Emanuele Zucca, Ewa Paszkiewicz-Kozik, Carla Minoia, Tetiana Skrypets, Yngvild Nuvin Blaker, Gilles Salles, Bertrand Coiffier
BACKGROUND: Histological transformation of follicular lymphoma to aggressive lymphoma is a serious event with a substantial effect on patient outcome. The aim of the Aristotle study was to assess the effect of rituximab on the risk of histological transformation and its outcome. METHODS: 11 cooperative groups or institutions across Europe contributed data to this study. Eligible patients (≥18 years) had histologically confirmed follicular lymphoma grade 1, 2, or 3a, diagnosed between Jan 2, 1997, and Dec 20, 2013...
August 2018: Lancet Haematology
Nicolas Clementy, Bruno Garcia, Clémentine André, Arnaud Bisson, Nazih Benhenda, Bertrand Pierre, Anne Bernard, Laurent Fauchier, Eric Piver, Dominique Babuty
INTRODUCTION: Mechanisms of maintenance of both atrial fibrillation and structural left ventricular disease are known to include fibrosis. Galectin-3, a biomarker of fibrosis, is elevated both in patients with heart failure and persistent atrial fibrillation. We sought to find whether galectin-3 has a prognostic value in patients with heart failure and a reduced left ventricular ejection fraction undergoing ablation of persistent atrial fibrillation. METHODS: Serum concentrations of galectin-3 were determined in a consecutive series of patients with an ejection fraction ≤40%, addressed for ablation of persistent atrial fibrillation...
2018: PloS One
Enida Gjoni, Clémentine Aguet, Daniela A Sahlender, Graham Knott, Ralf Schneggenburger
KEY POINTS: Neurons of the Lateral Superior Olive (LSO) in the brainstem receive powerful glycinergic inhibition that originates from the contralateral ear, and that plays an important role in sound localization. We investigated the ultrastructural basis for strong inhibition of LSO neurons by using serial block face scanning electron microscopy (SBEM). The soma and the proximal dendrite of an LSO neuron are surrounded by a high density of inhibitory axons, whereas excitatory axons are much sparser...
July 28, 2018: Journal of Physiology
T Quyen Nguyen, Magali Aumont-Niçaise, Jessica Andreani, Christophe Velours, Mélanie Chenon, Fernando Vilela, Clémentine Geneste, Paloma Fernández Varela, Paola Llinas, Julie Menetrey
JIP1 was first identified as scaffold protein for the MAP kinase JNK and is a cargo protein for the kinesin1 molecular motor. JIP1 plays significant and broad roles in neurons, mainly as a regulator of kinesin1-dependent transport, and is associated with human pathologies such as cancer and Alzheimer disease. JIP1 is specifically recruited by the kinesin-light chain 1 (KLC1) of kinesin1, but the details of this interaction are not yet fully elucidated. Here, using calorimetry, we extensively biochemically characterized the interaction between KLC1 and JIP1...
July 19, 2018: Journal of Biological Chemistry
Valerie T Ramirez, Wesley E P A van Oeffelen, Cristina Torres-Fuentes, Barbara Chruścicka, Clementine Druelle, Anna V Golubeva, Marcel van de Wouw, Timothy G Dinan, John F Cryan, Harriët Schellekens
The ghrelin receptor [growth hormone secretagogue receptor (GHSR)-1a] represents a promising pharmacologic target for the treatment of metabolic disorders, including obesity and cachexia, via central appetite modulation. The GHSR-1a has a complex pharmacology, highlighted by G-protein-dependent and -independent downstream signaling pathways and high basal constitutive activity. The functional selectivity and signaling bias of many GHSR-1a-specific ligands has not been fully characterized. In this study, we investigated the pharmacologic properties of ghrelin, MK-0677, L692,585, and [d-Lys3]-growth hormone-releasing peptide-6 (Dlys), JMV2959, and [d-Arg(1),d-Phe(5),d-Trp(7, 9),Leu(11)]-substance P (SP-analog)...
July 18, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Debora Trichez, Clément Auriol, Audrey Baylac, Romain Irague, Clémentine Dressaire, Marc Carnicer-Heras, Stéphanie Heux, Jean Marie François, Thomas Walther
BACKGROUND: Malate is a C4-dicarboxylic acid widely used as an acidulant in the food and beverage industry. Rational engineering has been performed in the past for the development of microbial strains capable of efficient production of this metabolite. However, as malate can be a precursor for specialty chemicals, such as 2,4-dihydroxybutyric acid, that require additional cofactors NADP(H) and ATP, we set out to reengineer Escherichia coli for Krebs cycle-dependent production of malic acid that can satisfy these requirements...
July 16, 2018: Microbial Cell Factories
Clementine J Edwards, Matteo Cella, Richard Emsley, Nicholas Tarrier, Til H M Wykes
BACKGROUND: It has been hypothesised that a reduction in anticipatory pleasure contributes to reduced levels of functioning in people with schizophrenia. Previous research on anticipatory pleasure, however, reports mixed findings and has not yet examined the link between anticipatory pleasure and activity. The aim of this study is to examine how pleasure anticipation is related to difficulties engaging in activity in people with schizophrenia. METHOD: A healthy control group (n = 44) and a group of individuals with schizophrenia (n = 36) completed an experience sampling study using portable devices...
July 6, 2018: Schizophrenia Research
Nicolas Clementy, Ambroise Fourquet, Clémentine Andre, Arnaud Bisson, Bertrand Pierre, Laurent Fauchier, Dominique Babuty, Denis Angoulvant
Palpitations are a frequent symptom in the general population, and if cardiac arrhythmias are the most frequent etiology, their diagnosis may be uncertain. We sought to see whether a specialized management of palpitations is associated with a high diagnostic accuracy in patients presenting with palpitations.Consecutive patients addressed for isolated palpitations in our outpatient cardiac unit were prospectively included in this observational cohort study. The initial management was standardized: 12-lead electrocardiogram (ECG) as early as possible, ECG monitoring, potentially followed by an individualized management...
July 2018: Medicine (Baltimore)
Jacques Avelino, Clémentine Allinne, Rolando Cerda, Laetitia Willocquet, Serge Savary
Assessment of crop loss due to multiple diseases and pests (D&P) is a necessary step in designing sustainable crop management systems. Understanding the drivers of D&P development and yield loss helps identify leverage points for crop health management. Crop loss assessment is also necessary for the quantification of D&P regulation service to identify promising systems where ecosystem service provision is optimized. In perennial crops, assessment of crop losses due to D&P is difficult, as injuries can affect yield over years...
July 11, 2018: Annual Review of Phytopathology
Benjamin Leuschel, Agnieszka Gwiazda, Wajdi Heni, Frédéric Diot, Shang-Yu Yu, Clémentine Bidaud, Laurent Vonna, Arnaud Ponche, Hamidou Haidara, Olivier Soppera
Deep-UV (DUV) laser patterning has been widely used in recent years for micro- and nanopatterning, taking advantage of the specific properties of irradiation with high-energy photons. In this paper, we show the usefulness of DUV laser patterning for preparing surfaces with controlled chemical properties at the micro- and nanoscale. Our motivation was to develop a simple and versatile method for chemical patterning at multiscales (from mm to nm) over relatively wide areas (mm2 to cm2 ). The chemical properties were provided by self-assembled monolayers (SAMs), prepared on glass or silicon wafers...
July 11, 2018: Scientific Reports
Helene Karcher, Shuai Fu, Jie Meng, Mikkel Zöllner Ankarfeldt, Orestis Efthimiou, Mark Belger, Josep Maria Haro, Lucien Abenhaim, Clementine Nordon
BACKGROUND: Phase III randomized controlled trials (RCT) typically exclude certain patient subgroups, thereby potentially jeopardizing estimation of a drug's effects when prescribed to wider populations and under routine care ("effectiveness"). Conversely, enrolling heterogeneous populations in RCTs can increase endpoint variability and compromise detection of a drug's effect. We developed the "RCT augmentation" method to quantitatively support RCT design in the identification of exclusion criteria to relax to address both of these considerations...
July 6, 2018: BMC Medical Research Methodology
Laurence Dumeige, Livie Chatelais, Claire Bouvattier, Marc De Kerdanet, Hyon Capucine, Blandine Esteva, Dinane Samara-Boustani, Delphine Zénaty, Marc Nicolino, Sabine Baron, Chantal Metz, Naud-Saudreau Catherine, Clementine Dupuis, Juliane Leger, Jean-Pierre Siffroi, Bruno Donadille, Sophie Christin-Maitre, Jean-Claude Carel, Regis Coutant, Laetitia Martinerie
OBJECTIVE: Few studies of patients with a 45,X/46,XY mosaicism have considered those with normal male phenotype. The purpose of this study was to evaluate the clinical outcome of 45,X/46,XY boys born with normal or minor abnormalities of external genitalia, notably in terms of growth and pubertal development. METHODS: Retrospective longitudinal study of 40 patients followed between 1982 and 2017 in France. RESULTS: Twenty patients had a prenatal diagnosis whereas 20 patients had a postnatal diagnosis, mainly for short stature...
July 4, 2018: European Journal of Endocrinology
Sihui Jiao, Bin Lu
CHENG Dan -an experience was summarized regarding the rules on the combination of acupuncture and herbal medicine for taiyan diseases. Through collecting the materials on the treatment for taiyang diseases with TCM by CHENG Dan -an, the acupoint prescriptions in medical cases were extracted. Using Excel 2010 software, the prescription database was set up. SPSS 23.0 software and Clementine 12.0 software were adopted for the frequency analysis, association rule analysis and cluster analysis. The top 3 high-frequency used acupoints are Zusanli (ST 36), Hegu (LI 4) and Jianshi (PC 5)...
June 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Marina As Daniele, Rasmané Ganaba, Sophie Sarrassat, Simon Cousens, Clémentine Rossier, Seydou Drabo, Djeneba Ouedraogo, Veronique Filippi
Objective: To determine whether an intervention to involve the male partners of pregnant women in maternity care influenced care-seeking, healthy breastfeeding and contraceptive practices after childbirth in urban Burkina Faso. Methods: In a non-blinded, multicentre, parallel-group, superiority trial, 1144 women were assigned by simple randomization to two study arms: 583 entered the intervention arm and 561 entered the control arm. All women were cohabiting with a male partner and had a low-risk pregnancy...
July 1, 2018: Bulletin of the World Health Organization
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