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Abdominal pain children

Marco Daniel Gulewitsch, Aiste Jusyte, Katja Weimer, Michael Schönenberg
Objective: Functional abdominal pain (AP) is a prevalent issue in childhood and adolescence. The contribution of psychosocial factors in the development and maintenance of this health problem is rather unclear, and experimental studies about underlying mechanisms are lacking. This study investigates whether experimentally induced social exclusion decreases sensory and pain thresholds in children suffering from AP. Subjects: Twenty children/adolescents with AP and 22 healthy controls...
December 13, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
M Rossi, G Bruno, M Chiusalupi, A Ciaramella
Poor emotional awareness (EA) seems to play an important role in the aetiology of functional somatic complaints featuring pain as a form of somatisation. The aim of this study was to shed more light on this relationship by investigating the links between pain, somatisation, and emotional awareness in a nonclinical population of 445 children aged 6-10. Assessing pain through the Children's Somatisation Inventory (CSI), a very high percentage of the entire sample complained of experiencing pain at least one site (84...
2018: Pain Research and Treatment
Mark C Kendall, Lucas J Castro Alves, Edward I Suh, Zachary L McCormick, Gildasio S De Oliveira
Regional anesthesia is becoming increasingly popular among anesthesiologists in the management of postoperative analgesia following pediatric surgery. The main objective of this review was to systematically evaluate the last 5 years of randomized controlled trials on the role of regional anesthesia techniques in alleviating postoperative pain associated with various pediatric surgical procedures. Forty studies on 2,408 pediatric patients were evaluated. The majority of the articles published from 2013 to 2017 reported that the use of regional anesthesia minimized postoperative pain and reduced opioid consumption...
2018: Local and Regional Anesthesia
Yao Xu, Jing Jing Wang, Fei Fei Liu, Yue Wu, Yang Fang Wu, Sama Samadli, Huang Huang Luo, Dong Dong Zhang, Peng Hu
Henoch-Schönlein purpura (HSP) is a common autoimmune vasculitis in childhood. The detailed pathogenesis of HSP is still unclear, whereas several types of predisposing factors have been proved to be the initial step. The objectives of present study were to analyze the distribution of predisposing factors, association of the predisposing factors with clinical manifestations and HSP relapse/recurrence. 1200 children with HSP were recruited between January 2015 and December 2017. We reviewed their laboratory tests and medical histories associated with HSP onset...
December 6, 2018: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
Margot Latimer, Sharon Rudderham, Lynn Lethbridge, Emily MacLeod, Katherine Harman, John R Sylliboy, Corey Filiaggi, G Allen Finley
BACKGROUND: Indigenous youth have higher rates of chronic health conditions interfering with healthy development, including high rates of ear, dental, chest and musculoskeletal pain, as well as headache, arthritis and mental health issues. This study explores differences in pain-related diagnoses in First Nations and non-First Nations children. METHODS: Data from a study population of age- and sex-matched First Nations and non-First Nations children and youth were accessed from a specific region of Atlantic Canada...
December 10, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
Lan-Jie Cheng, Shu-Cheng Zhang
BACKGROUND: Abdominal ascites is a common problem in general surgery. The causes include parasitic diseases, tuberculosis, malignancies, hypoalbuminemia, abdominal inflammatory diseases, and peritonitis. Eosinophilic gastroenteritis (EG) has also been reported to be an infrequent cause. To our knowledge, most instances of abdominal ascites from EG have occurred in adults and been reported by physicians or gastroenterologists. Herein, we report a small series of children who presented with eosinophilic ascites from a surgeon's perspective...
December 5, 2018: Clinics and Research in Hepatology and Gastroenterology
E Valavi, A Nickavar, A Aeene
BACKGROUND: Hematuria, either macroscopic or microscopic, is an incidental finding of multiple nephrologic or urologic disorders. Disturbances of urine inhibitors or promotors have been suggested as the potential causes of isolated idiopathic hematuria in children and its recurrence. Meanwhile, appropriate treatment of these risk factors might improve secondary asymptomatic or macroscopic hematuria. OBJECTIVES: The aim of this study was to identify contribution of urinary biochemical abnormalities in children with isolated idiopathic hematuria...
November 10, 2018: Journal of Pediatric Urology
Ralph Antonio Xavier Ferreira, Claire Fernandes Kubelka, Luis Guillermo Coca Velarde, Jorge Paulo Strogoff de Matos, Laura Cunha Ferreira, Mariana Mancebo Reid, Sérgio Setúbal, Solange Artimos de Oliveira
INTRODUCTION: Dengue is one of the most important mosquito-borne infections. Severe cases are more frequently observed in adults. However, in 2008, the State of Rio de Janeiro, Brazil, experienced a severe dengue epidemic that primarily affected children and caused many cases of dengue hemorrhagic fever (DHF) and death. METHODS: A cross-sectional analytical study was conducted to examine laboratory diagnosis and clinical epidemiologic factors for confirmed dengue cases in patients aged less than 16 years, from January to June 2008, at a municipal hospital in the City of Rio de Janeiro, Brazil...
November 2018: Revista da Sociedade Brasileira de Medicina Tropical
Carmine Noviello, Mercedes Romano, Alfonso Papparella, Andrea Ciavattini, Ascanio Martino, Giovanni Cobellis
Isolated tubal torsion (ITT) is a rare cause of acute abdominal pain. Preoperative diagnosis is difficult because of a lack of specific signs. Surgery is recommended to preserve the integrity of the tube. Seven patients of median age of 13 years (range 9 to 15) came to our observation for worsening abdominal pain, nausea and vomiting. On admission, all girls had blood tests and ultrasound. Laparoscopy was performed for diagnosis in all cases. The girls had one-month and one-year ultrasound and clinic follow up...
December 4, 2018: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
Rabia Miray Kisla Ekinci, Sibel Balci, Atil Bisgin, Bahriye Atmis, Dilek Dogruel, Derya Ufuk Altintas, Mustafa Yilmaz
OBJECTIVES: Henoch Schönlein Purpura (HSP) is characterized by non-thrombocytopenic palpable purpura, abdominal pain and arthralgia/arthritis. We aimed to describe the clinical presentations of children with HSP in a single center and compare the prevalence of each manifestations between patients with MEFV variants, particularly in exon 10 and those without. METHODS: This cohort retrospectively included 144 HSP (59 females, 85 males) patients without FMF symptoms and followed for at least 6 months...
December 4, 2018: Postgraduate Medicine
Fanhui Zhang, Lihua Chen, Shiqiang Shang, Kewen Jiang
RATIONALE: The presence of purpura is a compulsory criteria for the diagnosis of Henoch-Schönlein purpura (HSP). Typical purpura of HSP is distributed symmetrically over the extensor surfaces of the lower limbs, buttocks, and forearms with the occasional involvement of trunk and face in children. It occurs only involving the bottom of the feet has never been reported. PATIENT CONCERNS: A 7-year-old girl was admitted to the hospital with abdominal pain, vomiting, and fever...
November 2018: Medicine (Baltimore)
Burton I Korelitz, Bernard Partiula, Kelly Teagle, Arun Swaminath, Judy Schneider, Martin Ellington, Guillaume Stoffels
Objective: To seek the habits of pediatricians by which anorectal skin tags (AST) of Crohn's disease might be overlooked. Methods: Questionnaires were sent to pediatricians affiliated with the Northwell Health System. Results: Based on the responses, the majority of pediatricians did feel the abdomen of children presenting with abdominal pain or diarrhea but did not spread the buttocks to seek the presence of AST unless there was rectal pain, rectal bleeding, or, in some cases, loose stools...
November 2018: Inflammatory Intestinal Diseases
Maria Lalouni, Brjánn Ljótsson, Marianne Bonnert, Richard Ssegonja, Marc Benninga, Johan Bjureberg, Jens Högström, Hanna Sahlin, Magnus Simrén, Inna Feldman, Erik Hedman-Lagerlöf, Eva Serlachius, Ola Olén
BACKGROUND & AIMS: Scalable and effective treatments are needed for children with functional abdominal pain disorders (FAPDs). We performed a randomized controlled trial of the efficacy and cost effectiveness of cognitive behavioral therapy delivered online (internet CBT) compared to usual therapy. METHODS: We studied children (8-12 years old) diagnosed with FAPDs, based on the Rome IV criteria, in Sweden from September 2016 through April 2017. The patients were randomly assigned to groups that received 10 weeks of therapist-guided, internet-delivered cognitive behavioral therapy (internet CBT, n=46) or usual treatment (treatments within the healthcare and school systems, including medications and visits to doctors and other healthcare professionals; n=44)...
November 28, 2018: Clinical Gastroenterology and Hepatology
Anna Pärtty, Samuli Rautava, Marko Kalliomäki
The potential association between gut microbiota perturbations and childhood functional gastrointestinal disturbances opens interesting therapeutic and preventive possibilities with probiotics. The aim of this review was to evaluate current evidence on the efficacy of probiotics for the management of pediatric functional abdominal pain disorders, functional constipation and infantile colic. Thus far, no single strain, combination of strains or synbiotics can be recommended for the management of irritable bowel syndrome, functional abdominal pain or functional constipation in children...
November 29, 2018: Nutrients
Peter L Lu, Puck J J Blom, Qian Qian, Carlos A Velasco-Benítez, Marc A Benninga, Miguel Saps
Our objective is to compare coping methods, stress responses, and resilience in children with and without functional gastrointestinal disorders (FGIDs) in response to common sources of stress. We performed a case-control study. Children meeting criteria for FGIDs and matched controls completed measures of response to stress (Peer Stress, Family Stress, Academic Problems, and Recurrent Abdominal Pain versions of the Response to Stress Questionnaire) and resilience (Connor-Davidson Resilience Scale 10). We included 134 children with a FGID (57 with functional constipation and 74 with an abdominal pain-predominant FGID) and 135 controls...
November 27, 2018: Journal of Pediatric Gastroenterology and Nutrition
Marjolijn E W Timmerman, Monika Trzpis, Paul M A Broens
Introduction: Many children with acute abdominal pain and suspicion of appendicitis are diagnosed with constipation. Nevertheless, it can be difficult to differentiate between acute constipation and acute appendicitis because of similar symptoms and lack of diagnostic criteria. Consequently, constipation is often missed despite repeated consultations at the emergency department. We hypothesise that the diagnostic process can be improved and adequate treatment accelerated by supporting faecal evacuation in children with acute abdominal pain...
2018: BMJ Paediatrics Open
Rami Arrouk, Rachel E Herdes, Aryn C Karpinski, Paul E Hyman
Background: Oral serum-derived bovine immunoglobulin (SBI)/protein isolate is a medical food intended to manage chronic diarrhea. It has been shown to improve pain and diarrhea in adults with diarrhea-predominant irritable bowel syndrome (d-IBS). Aim: To determine if SBI can improve symptoms in children with d-IBS. Methods: We performed a randomized, double-blind, placebo-controlled, pilot study (NCT02609529) to evaluate the effectiveness of SBI in children 8-18 years with d-IBS...
2018: Pediatric Health, Medicine and Therapeutics
Brian Veauthier, Jaime R Hornecker
Crohn's disease is a chronic inflammatory condition that affects the gastrointestinal tract. It can cause lesions from mouth to anus and may result in extraintestinal complications. The prevalence of Crohn's disease is increasing in adults and children. Genetic predispositions to Crohn's disease have been identified, and specific environmental factors have been associated with its development. Common presenting symptoms include diarrhea, abdominal pain, rectal bleeding, fever, weight loss, and fatigue. Physical examination should identify unstable patients requiring immediate care, include an anorectal examination, and look for extraintestinal complications...
December 1, 2018: American Family Physician
Thomas Jaschinski, Christoph G Mosch, Michaela Eikermann, Edmund Am Neugebauer, Stefan Sauerland
BACKGROUND: The removal of the acute appendix is one of the most frequently performed surgical procedures. Open surgery associated with therapeutic efficacy has been the treatment of choice for acute appendicitis. However, in consequence of the evolution of endoscopic surgery, the operation can also be performed with minimally invasive surgery. Due to smaller incisions, the laparoscopic approach may be associated with reduced postoperative pain, reduced wound infection rate, and shorter time until return to normal activity...
November 28, 2018: Cochrane Database of Systematic Reviews
Benjamin O Wolthers, Thomas L Frandsen, Chirag J Patel, Rachid Abaji, Andishe Attarbaschi, Shlomit Barzilai, Antonella Colombini, Gabriele Escherich, Marie Grosjean, Maja Krajinovic, Eric Larsen, Der-Cherng Liang, Anja Möricke, Kirsten K Rasmussen, Sujith Samarasinghe, Lewis B Silverman, Inge M van der Sluis, Martin Stanulla, Morten Tulstrup, Rachita Yadav, Wenjian Yang, Ester Zapotocka, Ramneek Gupta, Kjeld Schmiegelow
Asparaginase-associated pancreatitis is a life-threatening toxicity to childhood acute lymphoblastic leukemia treatment. To elucidate genetic predisposition and asparaginase-associated pancreatitis pathogenesis, ten acute lymphoblastic leukemia trial groups contributed remission samples from patients aged 1.0-17.9 years and treated from 2000-2016. Cases were defined (n=244) by at least two of the following criteria: i) abdominal pain, ii) pancreatic enzymes >3 x upper normal limit, iii) imaging compatible with asparaginase-associated pancreatitis...
November 22, 2018: Haematologica
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